LOCUS       NM_001048217             742 bp    mRNA    linear   ROD 27-FEB-2025
DEFINITION  Mus musculus serine peptidase inhibitor, Kazal type 11 (Spink11),
            mRNA.
ACCESSION   NM_001048217 XM_484760 XM_910662 XM_989858
VERSION     NM_001048217.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Jalkanen,J., Kotimaki,M., Huhtaniemi,I. and Poutanen,M.
  TITLE     Novel epididymal protease inhibitors with Kazal or WAP family
            domain
  JOURNAL   Biochem Biophys Res Commun 349 (1), 245-254 (2006)
   PUBMED   16930550
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124181.3.
            
            On Mar 13, 2019 this sequence version replaced NM_001048217.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ437331.1, AK136741.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                AC124181.3         169266-169333       c
            69-139              AC124181.3         168797-168867       c
            140-183             AC124181.3         165746-165789       c
            184-296             AC124181.3         164764-164876       c
            297-742             AC124181.3         163205-163650       c
FEATURES             Location/Qualifiers
     source          1..742
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 23.74 cM"
     gene            1..742
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /note="serine peptidase inhibitor, Kazal type 11"
                     /db_xref="GeneID:433181"
                     /db_xref="MGI:MGI:3588289"
     exon            1..68
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            69..139
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..345
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /note="serine protease inhibitor Kazal-type 11"
                     /codon_start=1
                     /product="serine protease inhibitor Kazal-type 11
                     precursor"
                     /protein_id="NP_001041682.3"
                     /db_xref="GeneID:433181"
                     /db_xref="MGI:MGI:3588289"
                     /translation="MSSTWIKFLFILTLVLLPYFVAESAVASPESLRKVPNCTLYKSE
                     SDCSRTLIPVCADNQMTYYNACYFCLEQLVSPIKYKYHGICTKE"
     exon            140..183
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            184..296
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            297..742
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      720..725
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      742
                     /gene="Spink11"
                     /gene_synonym="9230112K01Rik"
                     /note="major polyA site"
ORIGIN      
        1 atgtgtaacg aggtagaaga acaaacagta agcacagagt gctggtacat cttcatttct
       61 gttttcagat ttgataaaat gtcctcaaca tggatcaaat ttctttttat tctgactttg
      121 gtacttcttc cttattttgt tgcagagtct gctgttgcaa gtccagagag tcttagaaaa
      181 gtgccaaatt gtaccttgta taagagtgaa tctgactgct ccagaacgct gatcccagtt
      241 tgtgcagata atcaaatgac atattacaat gcatgttact tctgcctaga acaattagta
      301 tcaccaatta aatataaata ccatggtatt tgtactaaag aataatggtt tcatggtggt
      361 tcatgcaatc aagtggaatg ttctcaactg gtggcttaaa ttcctaatca acaaatgaat
      421 tcgtctatga ttcataatgt ggcgtagaga agattaaaga atctttccaa tgtgaacctg
      481 agattaaata atattgaatg agagttgaac aagaaacatt ttctcaggtt gccaaatgtt
      541 tagttaagaa attgaaccta caggaagaaa catatattca cactaaaaga taattttcct
      601 ctgttatata tacatgttag gcctgtttta ttttcaatga tttgatggtg atataaatac
      661 ctattaattt ttgtattata ctacataaac tgtgagtttt aatcatagat gttctaatca
      721 ataaaatgtt taataatttc aa
//
