LOCUS       NM_001033139            3151 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus spindlin interactor and repressor of chromatin binding
            (Spindoc), transcript variant 1, mRNA.
ACCESSION   NM_001033139 XM_129071 XM_896185 XM_896195 XM_896204 XM_896213
            XM_896219 XM_896224 XM_912777 XM_922495 XM_922500 XM_922504
            XM_922508 XM_922513 XM_922518
VERSION     NM_001033139.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3151)
  AUTHORS   Yang,F., Chen,J., Liu,B., Gao,G., Sebastian,M., Jeter,C., Shen,J.,
            Person,M.D. and Bedford,M.T.
  TITLE     SPINDOC binds PARP1 to facilitate PARylation
  JOURNAL   Nat Commun 12 (1), 6362 (2021)
   PUBMED   34737271
  REMARK    GeneRIF: SPINDOC binds PARP1 to facilitate PARylation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3151)
  AUTHORS   Jiang,X., Zhu,X., Cheng,Y., Azhar,M., Xing,X., Li,W., Cao,Y.,
            Shi,Q. and Bao,J.
  TITLE     The Spin1 interactor, Spindoc, is dispensable for meiotic division,
            but essential for haploid spermatid development in mice
  JOURNAL   Reprod Biol Endocrinol 19 (1), 144 (2021)
   PUBMED   34526015
  REMARK    GeneRIF: The Spin1 interactor, Spindoc, is dispensable for meiotic
            division, but essential for haploid spermatid development in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3151)
  AUTHORS   Bae,N., Gao,M., Li,X., Premkumar,T., Sbardella,G., Chen,J. and
            Bedford,M.T.
  TITLE     A transcriptional coregulator, SPIN.DOC, attenuates the coactivator
            activity of Spindlin1
  JOURNAL   J Biol Chem 292 (51), 20808-20817 (2017)
   PUBMED   29061846
REFERENCE   4  (bases 1 to 3151)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129188.3.
            
            On Jan 12, 2022 this sequence version replaced NM_001033139.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK166227.1, AK090385.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-322               AC129188.3         96160-96481         c
            323-652             AC129188.3         88009-88338         c
            653-802             AC129188.3         87784-87933         c
            803-928             AC129188.3         87510-87635         c
            929-1126            AC129188.3         87145-87342         c
            1127-3151           AC129188.3         69951-71975         c
FEATURES             Location/Qualifiers
     source          1..3151
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 5.32 cM"
     gene            1..3151
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /note="spindlin interactor and repressor of chromatin
                     binding"
                     /db_xref="GeneID:68229"
                     /db_xref="MGI:MGI:2147611"
     exon            1..322
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..1338
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C11orf84 homolog; SPIN1-docking
                     protein; spindlin interactor and repressor of
                     chromatin-binding protein"
                     /codon_start=1
                     /product="spindlin interactor and repressor of
                     chromatin-binding protein isoform 1"
                     /protein_id="NP_001028311.2"
                     /db_xref="CCDS:CCDS29523.1"
                     /db_xref="GeneID:68229"
                     /db_xref="MGI:MGI:2147611"
                     /translation="MALKAKGAAALDCFEVTLKCEEGDDDDEAVVVAVIPRPEPMLRV
                     TQQEKTPPPRPNLLEAGVEGCEELKQQVSWEQEFLVGNSPGGSGRALCMVCGAEIRSP
                     SADTARAHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDIQADQPSLPSLESGQDGQ
                     PDPISNPDPVRMPAEIVVLLDSEDNPSLPKRLRPRGLRPLELPVTPVIEQGNKKPRGQ
                     RWKESPENEPARKKRSRHMTKILDPDPDPPSPESPTETFAAPAEVRHFTDGSFPPGFV
                     LQLFSHTQLRTTDCKDSSKDSRAAEGLPQPQNPSSASPPGLRGTLDLQVIRVRMEEPP
                     AVSLLQDWSKHPQGTKGVGTGDKPDWPTVLSESSATVKGQPKAGSGV"
     exon            323..652
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /inference="alignment:Splign:2.1.0"
     exon            653..802
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /inference="alignment:Splign:2.1.0"
     exon            803..928
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1126
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..3151
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1903..1908
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /note="hexamer: AATAAA"
     polyA_site      1928
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /note="major polyA site"
     regulatory      3131..3136
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
                     /note="hexamer: AATAAA"
     polyA_site      3151
                     /gene="Spindoc"
                     /gene_synonym="1700105P06Rik; SPIN-DOC"
ORIGIN      
        1 ggatcgaacc ctccccgccc ggggtcgtga cgcgttgaag cccgtggctg gcggggcggc
       61 cgggcgagcg gcgggtgagc taggcgagcc gcgggcccgg ggtggtccgg ggcaggaggc
      121 ggccgccaca ggcggtgcgc cgaggtctgt gcgaacgtcc tcggctatcc ggtcgccctt
      181 cttcgcctcg ccatggccct gaaagccaag ggcgccgcgg ctctggattg cttcgaggtg
      241 acgctcaagt gtgaggaagg ggatgatgac gacgaggccg tggtggtggc cgtgatcccg
      301 cggcccgagc cgatgctccg agtaacccaa caggaaaaga cgccgccacc tcggcctaac
      361 ctgctggaag caggtgttga aggctgtgag gagctcaagc agcaagtgtc atgggagcag
      421 gagttcctgg tggggaacag cccaggaggc agtggacggg cgctgtgcat ggtgtgtggg
      481 gctgagatcc ggtccccatc agcagacact gctcgcgcac acatcctgga gcagcatcct
      541 cacaccctgg acctgagccc ctctgagaag agcaacatct tagaagcctg gagtgaaggg
      601 gttgcccttc tgcaagacat ccaagctgac cagccatccc tgcccagcct agagtcaggc
      661 caggatggcc agccagaccc catctccaac ccggatcctg tcaggatgcc agcagagata
      721 gtggtcctct tggattccga ggacaaccca tcccttccta agaggctccg gcccagagga
      781 ctccgccccc ttgagctgcc cgttacccct gtcatagagc aagggaataa aaagccccgt
      841 ggtcagagat ggaaagagtc ccctgagaat gaacctgcta gaaagaagag aagcaggcat
      901 atgaccaaaa tcttggaccc tgacccagac cccccgtctc ctgagtcacc cacagagaca
      961 ttcgcagcac cagctgaagt ccgacacttc actgatggca gcttccctcc tggcttcgtc
     1021 ctccagctct tctcccacac tcagctcagg accactgact gtaaggactc ttctaaggac
     1081 agcagagcag cagagggcct gccccagcca caaaacccct cttcagcctc ccctccgggg
     1141 ctccgtggga cactggatct ccaggttatc cgtgttcgga tggaggaacc accagccgtc
     1201 agcctcttac aggactggtc caagcacccc cagggcacca agggggtggg aacaggtgac
     1261 aagccagact ggcccacagt tctgtcagaa tccagtgcca ctgttaaggg acaaccaaag
     1321 gcagggagtg gagtataagt tttcagtttt ctagagaggg aggggcggga agaaggaaag
     1381 gtgggcggga ggaggtagtt atcccccatt ggcttaaatc tcagatctgc ctagcttggc
     1441 cacctgatgg agatttttta aaaccaggtg ccaggacaat gtggagggag gaggggtggc
     1501 atcactgtca catcgggcta ctggaaaatg cctgctcttg gccaagccgg aggtaggcag
     1561 aggcggctta ggttgttggg tggtaggtaa ggcattgggc ctgtggagaa caccttccct
     1621 aatccttcgc tgacctaccc tctggcccca tatctcctcc tccctctcag ctccccacca
     1681 ttctcccctg gcacagtgcc ttatgcagag gtggtcatga tggggttgga actgagtccc
     1741 actacctcgg gggacacctt tcctccccca cttctggctc ctacagcagg aggcctccat
     1801 tacctcttac cgccttgtcc ctgccgaggg ctcccgttac aaccccttta cctgttgtcc
     1861 tgttgcatct attgtcctgt tgtatatatt gcctttgttg acaataaatt attttttttt
     1921 tattaaaagt tctgtgtggg ctatcattgg gaaaggggca tattcttaga gcagattgag
     1981 gggcaggaaa ccgaaaagtg gtcctgagtg ggagccagag acccctgcca gggcagagca
     2041 gcagtgagcc cagaacagag gttgcttgga cctcagggtc tgttttaact taatgtcagt
     2101 cgcctgagag acccattttc tttacttgac ctactgaccc acctggtagg cctctgtcca
     2161 agcaaagcta ctatggggct agggacactc ctacccaagg agctaagagt tagtgggccc
     2221 tgaacttggc cagcctgcac tgacatttcc tctgatgtga aggtggtaca tccctgcatt
     2281 ctcaaagggc tgtgcactcc actatacact tcacccctgt tcctcagcct caatccaagt
     2341 ctgcctgggg tctgcagatt ttaggcatcc tgagctatcg ctgcatagac ctaatctgtg
     2401 gggttttgca cttggggtga aaatgaatgt cccagattgc ttactctcaa atcctaggag
     2461 gtgaggccac cccacactgc tgactgttcc tggtatatta tggagacttg gggaaaggta
     2521 aaatgaagcc tcgcctccat caggaagagt cagggtatgc tgtgtgcttg cttaagctac
     2581 tgttcccaga ccagagatct catactggac ccaggctgag aattggccct gctaagccat
     2641 ctgtattctc aggaggagcc caagaaggta gaaggtcctt gtccaggaga agaggagacc
     2701 gaaatgaagt agatgcagga gttaaaggtt caaggtccat catgtccaga atgtcccagc
     2761 cattgtctgg gccacaggac acctgggtct gtatctgttt ctgtaggtta gcacagtttg
     2821 tatgctccct aaaaataatt tagatgtaga ctgtctctga aagcactgtg ttgaaattgc
     2881 aggtggtttc tgtccctaca actgtgtgac tttacattta tgtcaacttg tttttaaaac
     2941 attgtatttt tcacaaagta ttgaggaaac tcataaaaga ttgtgttgta aaatgattat
     3001 ccaaacgctt gcccctttgt ggttgtatga acctgatttg tcttagactg tgaactctgt
     3061 ggggcaggga ccagactgca ttaacttggt atttctggtg tcctgcatag ggctcggcac
     3121 ataagtactc aataaatgtc tgtcaaatgc c
//
