LOCUS       NM_178753               4176 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus spindlin family, member 4 (Spin4), mRNA.
ACCESSION   NM_178753
VERSION     NM_178753.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4176)
  AUTHORS   Lui,J.C., Wagner,J., Zhou,E., Dong,L., Barnes,K.M., Jee,Y.H. and
            Baron,J.
  TITLE     Loss-of-function variant in SPIN4 causes an X-linked overgrowth
            syndrome
  JOURNAL   JCI Insight 8 (9), e167074 (2023)
   PUBMED   36927955
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK036158.1, AK147852.1 and BB059605.1.
            
            On Nov 2, 2007 this sequence version replaced NM_178753.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK036158.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2010              AK036158.1         2-2011
            2011-3884           AK147852.1         1978-3851
            3885-4173           AK036158.1         3894-4182
            4174-4176           BB059605.1         230-232
FEATURES             Location/Qualifiers
     source          1..4176
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 41.83 cM"
     gene            1..4176
                     /gene="Spin4"
                     /gene_synonym="9630042H07Rik"
                     /note="spindlin family, member 4"
                     /db_xref="GeneID:270624"
                     /db_xref="MGI:MGI:2444925"
     exon            1..4176
                     /gene="Spin4"
                     /gene_synonym="9630042H07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             489..1238
                     /gene="Spin4"
                     /gene_synonym="9630042H07Rik"
                     /note="novel Spin/Ssty repeat containing protein"
                     /codon_start=1
                     /product="spindlin-4"
                     /protein_id="NP_848868.1"
                     /db_xref="CCDS:CCDS30282.1"
                     /db_xref="GeneID:270624"
                     /db_xref="MGI:MGI:2444925"
                     /translation="MSPPTVPPTGVDGVSAYLMKKRHTHKKQRRKPTFLTHRNIVGCR
                     IQHGWKEGNEPVEQWKGTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILP
                     ERVPSPRIDSRLADSLVGKAVGHVFEGEHGKKDEWKGMVLARAPIMDTWFYITYEKDP
                     VLYMYTLLDDYKDGDLRIIPDSNYYFPAAEQEPGEVLDSLVGKQVEHAKDDGSKRTGI
                     FIHQVVAKPSVYFIKFDDDIHIYVYGLVKTP"
     regulatory      4144..4149
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spin4"
                     /gene_synonym="9630042H07Rik"
     regulatory      4159..4164
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spin4"
                     /gene_synonym="9630042H07Rik"
     polyA_site      4176
                     /gene="Spin4"
                     /gene_synonym="9630042H07Rik"
ORIGIN      
        1 aagctgacaa gcgctgccaa gaccaggccg cgcaaagcgc aaactgctgg gagacgtgct
       61 actgcctgca ctttcgtggc cgcgaaacat ccctgttatc tccggtccag gttaacagtc
      121 cacttcttct ctgttgccgt tctgcgaccg cagcagcgtt gacaacagct aagtggcgga
      181 ttctggctgg gacgtgggct tgggagtccg ggaaggcgcc aggggcggac agaacgaacc
      241 cgggagcccg ccatctctct ggagccatca ctattgcagt cacccctccc tgaaggagga
      301 aaaaagcact agtgagcggc actctctgtc tcagttccca gtcagttagc tcttttctga
      361 caaaatctga aaagaggact gatacagtct ctcggatcgc gaaaaatatc tgccgttgga
      421 cactgctgac tgttagtcag cttgttaagc aaagagcagc tttactttgg ccaccgaagc
      481 ctcgagccat gtctcctccg actgtgcctc ctactggggt ggatggtgtg tccgcgtacc
      541 tgatgaagaa aaggcacact cacaagaagc agcgccgtaa gcccactttc ctcactcata
      601 ggaacatcgt gggctgccgc attcaacacg gctggaaaga aggcaatgag cccgtggagc
      661 aatggaaagg tactgtgctc gagcaggtct ccgtgaagcc cactctgtat atcatcaaat
      721 atgatggcaa agacagtgtg tacggactgg aactgcacag agataagaga gttttagcgc
      781 tggagattct tcctgagaga gttccttctc ctcgcattga ctctcgcctg gccgattccc
      841 tggttgggaa ggcagtggga catgtgttcg aaggtgagca tggcaagaaa gatgagtgga
      901 agggtatggt gttggcgcga gcccccatca tggatacttg gttttacatc acctacgaga
      961 aagatccggt cctctatatg tacaccctgc tggacgacta caaagatggt gacctgcgta
     1021 tcattccaga ttccaactac tacttccctg cagctgaaca ggagcctggg gaggtgctcg
     1081 acagccttgt gggcaagcag gtggaacacg ccaaagacga cgggtccaag agaactggga
     1141 tctttattca tcaggtggta gccaagccat ctgtctactt cattaagttt gatgatgata
     1201 ttcacattta tgtctatggc ttggtgaaaa ccccgtaagt ttatagacct ctttgcgaaa
     1261 cgtgtggaac tatcagagga taaatatttt atgttctcaa aattaagttt ttctgaggtc
     1321 aattttgagg tcaaaagttc tggacagtgg ctaaatctta ttgtgcctcc atatcttata
     1381 ttgactgttt tccagttctg actcaagtat atgttggtac ttttgttctt tgttttataa
     1441 ttgaaatttt aaattggctg ctaagaaaaa aagagaagtg tttggattca ccgaaacaac
     1501 tcaaaagtag ataaactgtg caacgtggct tctgctccct tccccctctt tctaattctt
     1561 ccccttagtt tgagaatttg gcatttttct tgggatgttt tccctgctct caagcagaaa
     1621 cttcaatgta acttttgtaa aactgacttc catatgatat ggtttttgat aaatggcaca
     1681 gtcagtctct gtccgtcact ctcatacttc ctctcaccag tgttcacagt ccatacagat
     1741 gtgccaaaaa gtatccattc tggtattggt gggcatttat ttcctttttt actcataatg
     1801 atgttttatt gtattaaggt gctcttattt ctatagaagt gttatgtagg tgtatattta
     1861 gttttaagaa ctattgcaag gttgccatcc actggtcttt gatgtttgca acgctgacag
     1921 gtagaacgtt ccatgggttc ctgattattt gatgtttacc tgactcaatg agacttattt
     1981 ttttctactt gggatatttc tctttttttg ttttgctaat tcctattctt tgtttcttgt
     2041 ctatatatac atatatatat tcagttgata ttttccatgt aaagttatag gaatttctac
     2101 aatgaaagta catttaatct tttttatttc atgtgttaat gaactttata ttgttattaa
     2161 tctttattgt tcactttaca attttaaaaa cttaatttta taatttttaa atgtttatgt
     2221 cttttataaa tttttagttt cctatcttct tcagacaggt gtccctaacc taggtcatac
     2281 caatattcac ttggtttttc ttttataatc tttattatat ttaaattttt atctacctga
     2341 aattcatttt tgcatatgct aatacatagg gactcaactc taaatatttt gcattacata
     2401 ttctactgta gaaattactt tttaaaaaat cactcttttt caaatttctg agtgaaagtt
     2461 aattttaaac ataataccag accatgagtt tcagaaactg gaataacaaa ttccctttca
     2521 atagttgttt ttctttctta ttataattta tcctcaacat tcatcctttc aagagaaaaa
     2581 aaaacaatgc attttattga tattttgaaa gggtctgata cttatcagaa ttgcatcaat
     2641 tttctgtatt cttatataca agaataaaat taatagtgat attcttacca cacaagagat
     2701 ttggtagatc attgaaatat ttttatcttg ttttcataac attttttcat ataggtcatt
     2761 catatcaaat ggaatttatt tttgcagtta tcaaattttg taataagttg aatatttttc
     2821 catcttataa gtaacttttt atttttatca ataaagcaaa tctacagatt ttatattttt
     2881 atcttttatc caatgagttt atttaatcct atatgttaca ttggatgtta aattagaaac
     2941 ttggattttc ttgatatata caatcatttt gtatgtaaat acagataatt ttatttcttc
     3001 taatgcttat acttattagt ataacattag ctggattttc cagagcagtg ttatgtgatg
     3061 atgatggcag acatgccttt ttctatttct aatttttatg agaatgactt tattgtttca
     3121 tgtgtgactt tgttgttgat tgttggtaag tagttattca tgtttagaaa ttccttctgt
     3181 tcttgttttt atatagtatt actattagaa atgtctcctt gattttatca atgtcttttc
     3241 aatatccatt attaaacata tagttttttt aatttgttga tgcatgattt attagaaagc
     3301 taggtactta gtattacaac aaacctttat ttctggaata aatcctactt ggttatggta
     3361 aaatagccat ttattatttt gtcgtatttt atttaccaat aatgcactta tacttgattt
     3421 gcattccaaa gtaaaattac agttttagat tactctttgt atttttaatt gaattaacag
     3481 acaacaggtt gtgtcttttt ttcataagct gtctctatga agctttgtca ttaaaattct
     3541 attagcttaa aaaatgactg agtaaaatag cactagaagt tttttttttt ttaagttacc
     3601 tgagactaag ctataaaaca ttgaaatcct gggaatgaat tttattaggt atctttaatg
     3661 cattccctga tattttctca gtggcaattg gctttttcag actttttgtt actacagaat
     3721 atatattttt ctgtcattta cagaatatat attctctgtc aattacacac gaagttgaaa
     3781 gctgcttata ttataaaatt tgctgattat ttttatgtgc tgtatgtcat tatgtattag
     3841 cccagttcag aaaatgtaat aaattcatca gctataatgg tagtataatt atctttgtat
     3901 tcttttattt actagaaaaa tgaggaaaaa attaaaaaaa atgaaagatg tgaaaacatt
     3961 tgtttacctc ccctccaaat tagcagatat ctatactttg acatgtttac tttaaatgca
     4021 gatttatatt gcaattggtc agtattaatg gctaataaat tcatttgcaa ctaccacacc
     4081 acctcttctg cagaggcgaa cactgtcatg aatttggtgc tcatgtttta tatatttact
     4141 aaaaataaat tatgtacaaa taaaactata accaat
//
