LOCUS       XM_036153276            2840 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus sphingosine kinase 2 (Sphk2), transcript
            variant X1, mRNA.
ACCESSION   XM_036153276
VERSION     XM_036153276.1
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000073.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2840
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="7"
     gene            1..2840
                     /gene="Sphk2"
                     /gene_synonym="Sk2; Spk2"
                     /note="sphingosine kinase 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 8
                     mRNAs, 12 ESTs, 364 long SRA reads, 10 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 20 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:56632"
                     /db_xref="MGI:MGI:1861380"
     CDS             528..2381
                     /gene="Sphk2"
                     /gene_synonym="Sk2; Spk2"
                     /codon_start=1
                     /product="sphingosine kinase 2 isoform X1"
                     /protein_id="XP_036009169.1"
                     /db_xref="GeneID:56632"
                     /db_xref="MGI:MGI:1861380"
                     /translation="MAPPPLLPVAASTPILHGEFGSYPANGPRFALTLTTQALHIQRL
                     RPKPEARPRDGLVSLDEVSGCGTLQSRSPEDTAAYFCIYTYPRGRRGGRRRATRTFRA
                     DGATTYEENRAEAQRWATALTCLLRGVPLSGDQEITPELLPRKPRLLILVNPFGGRGL
                     AWQRCMDHVVPMISEAGLSFNLIQTERQNHARELVQGLSLSEWEGIVTVSGDGLLYEV
                     LNGLLDRPDWEDAVRMPIGVLPCGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRG
                     GSHPLDLLSVTLASGSRCFSFLSVAWGFLSDVDIHSERFRALGSARFTLGAVLGLASL
                     HTYRGRLSYLPATTEPALPIPGHSLPRAKSELVLAPAPAPAATHSPLHRSVSDLPLPL
                     PQPALVSPGSPEPLPDLSLNGGGPELTGDWGGAGDAPLSPDPLLPSSPNALKTAQLSP
                     IAEGPPEMPASSGFLPPTHSAPEASTWGPVDHLLPPLGSPLPQDWVTIEGEFVLMLGI
                     LPSHLCADLMAAPHARFDDGVVHLCWVRSGISRAALLRILLAMEHGNHFSLGCPHLGY
                     AAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVHPGLATLLTGPAGQKPQA"
ORIGIN      
        1 tgtgggagga ccgagtaaac cgaggcttcc agaaccaaag agaagtcagc ctgaggaaag
       61 ggctgggacc cggagcctct ctggcctttc cccgtccctg ctctaacact ctccaggggt
      121 aaagggaccg gagaatcaga gacatgatcg gagcttgctg gacgagtcgc gtggtgactc
      181 tctggccgca cgccgaccgc ttctcggtgg ctcgcggagg acccggtggg ctgtgtgtcg
      241 gagactggtt gaactggccc aacattttcg atgtacatat tgatgtgcag agaaggcacg
      301 cagaactccc ggtttggaaa gcgggtagat aacaagctcc agagagactg aaatagagac
      361 catgacggtg gttggaggtg tggaggcccg aggcctccga agtagctggg atcaccgtct
      421 ttcaacactt ggcctggctc tgccatttaa agttgtgatc ttggaggctg gtccaggagc
      481 tgaccacaag ccaagagcct aggagtgctt gggactgaac cagggtcatg gccccaccac
      541 cactactgcc agtggctgcc agcactccaa tcctgcacgg cgagtttggt tcctacccgg
      601 ccaacggccc acggtttgcc ctcaccctca caacacaagc cctacacata cagcgactac
      661 gcccaaagcc agaagcccgg ccccgagatg gtctagtctc tctggatgag gtctcgggct
      721 gtggcaccct gcagagccgt agccccgagg acactgcagc ctacttctgc atctacacct
      781 acccacgtgg ccgtcgaggg ggccggcgca gagctacgcg gaccttccgg gcggatgggg
      841 ccaccactta tgaggagaat cgtgcagagg cccagcgctg ggccactgcc ctcacgtgtc
      901 tcctccgagg agtgcctctg tcaggggacc aggaaatcac ccctgaattg ctgccccgga
      961 agcccaggct gctcatattg gtcaatccct ttggggggcg gggcctggcc tggcagcgct
     1021 gtatggacca cgtggtgcca atgatctctg aagctgggct gtccttcaac ctcatacaga
     1081 cagaacgaca gaaccatgcc cgtgagctgg tgcaggggtt aagcctgagt gagtgggaag
     1141 gcattgtcac tgtgtctgga gacgggctgc tttacgaggt gctgaatggg ctccttgatc
     1201 ggccagactg ggaggatgcc gtgcggatgc ccattggtgt cctcccctgt ggatcgggca
     1261 atgcgctagc tggggcggtg aaccatcatg gcgggtttga gcaggttgtc ggtgttgacc
     1321 tgttgctcaa ctgctcgctt cttctctgcc gtggtggcag ccatcctctg gacctgctct
     1381 ctgtgacgct agcctcggga tcccgctgtt tttccttcct gtcagtggcc tggggattct
     1441 tgtcagatgt ggacattcac agtgagcgct tcagggccct gggcagcgct cgattcacac
     1501 tgggtgcagt gctaggcctg gcctcgttgc atacctaccg tggacgcctc tcctacctcc
     1561 ccgctaccac agaaccagcc ttgcccatcc caggccacag tctgcctcga gccaagtcag
     1621 aactagtctt ggctccagcc ccagcccccg ccgccaccca ctcgcctcta catcgatctg
     1681 tgtctgacct gcccctgccc cttccccagc ctgccttggt ctcccctggc tcccctgagc
     1741 ccctgcctga cctgtccctc aatggtggtg gtccagagct gactggagac tggggaggag
     1801 ctggggatgc acctctgtcc ccagacccac tgctgccttc atcccccaac gctctcaaaa
     1861 cagctcagct ttcacccatc gctgaagggc ccccagaaat gccagcatct tcggggttcc
     1921 tgcctcccac ccacagtgcc ccagaagcct ctacctgggg cccagtggac cacctcctcc
     1981 ctcccctggg ctctccactg ccccaagact gggtgacaat agagggggag tttgtactca
     2041 tgttgggcat cttgccgagc cacctctgcg cagacctgat ggcagcccca catgcacgct
     2101 ttgatgatgg cgttgtgcac ctgtgttggg tgcggagcgg catctcacgg gctgcacttc
     2161 tacgcatttt gctggccatg gagcatggaa accacttcag cctgggctgc ccccatctgg
     2221 gctatgctgc agcacgtgcc ttccgccttg aaccactcac gcctcgtggc ctgctcactg
     2281 tagatgggga gttagtggag tatgggccaa tacaggcgca ggtgcaccca ggtctcgcca
     2341 cgctgctcac tgggcctgca ggtcaaaagc cacaagcctg aacgagccta aaagcatggc
     2401 gagttggtgg aaccagcgcc ccataggcta agatctatca tttacaggta gaagtggggc
     2461 ccgcactcag aactgtgagg agggtggaga gtggtcctga ccctcagttc ccagaggacc
     2521 tagaggctcg agggtggggc ctgcctttct tgatgtccaa tgatggggcc tggaatgtat
     2581 gagctagcaa ggcttcttca gcttattgac cagccagggt ttcttcttgc ctactccggt
     2641 gcctctactt gactggccaa tcagcccttg aggggcaggt tcccccaggt ggtccccaga
     2701 tttgcactaa tgttcctccc ctggccagtt agggatggga tgttctgtgt cttgtgtgtc
     2761 cctctcccta gtctaaaaag caattgaaaa ggtctatgca ataaaggttg ttgcttccct
     2821 ctaggccttc accccttcca
//
