LOCUS       XM_006541012            2441 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus sphingosine kinase 2 (Sphk2), transcript
            variant X2, mRNA.
ACCESSION   XM_006541012
VERSION     XM_006541012.5
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000073.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006541012.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2441
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="7"
     gene            1..2441
                     /gene="Sphk2"
                     /gene_synonym="Sk2; Spk2"
                     /note="sphingosine kinase 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 6
                     mRNAs, 6 ESTs, 346 long SRA reads, 10 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 30 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:56632"
                     /db_xref="MGI:MGI:1861380"
     CDS             124..1977
                     /gene="Sphk2"
                     /gene_synonym="Sk2; Spk2"
                     /codon_start=1
                     /product="sphingosine kinase 2 isoform X1"
                     /protein_id="XP_006541075.1"
                     /db_xref="GeneID:56632"
                     /db_xref="MGI:MGI:1861380"
                     /translation="MAPPPLLPVAASTPILHGEFGSYPANGPRFALTLTTQALHIQRL
                     RPKPEARPRDGLVSLDEVSGCGTLQSRSPEDTAAYFCIYTYPRGRRGGRRRATRTFRA
                     DGATTYEENRAEAQRWATALTCLLRGVPLSGDQEITPELLPRKPRLLILVNPFGGRGL
                     AWQRCMDHVVPMISEAGLSFNLIQTERQNHARELVQGLSLSEWEGIVTVSGDGLLYEV
                     LNGLLDRPDWEDAVRMPIGVLPCGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRG
                     GSHPLDLLSVTLASGSRCFSFLSVAWGFLSDVDIHSERFRALGSARFTLGAVLGLASL
                     HTYRGRLSYLPATTEPALPIPGHSLPRAKSELVLAPAPAPAATHSPLHRSVSDLPLPL
                     PQPALVSPGSPEPLPDLSLNGGGPELTGDWGGAGDAPLSPDPLLPSSPNALKTAQLSP
                     IAEGPPEMPASSGFLPPTHSAPEASTWGPVDHLLPPLGSPLPQDWVTIEGEFVLMLGI
                     LPSHLCADLMAAPHARFDDGVVHLCWVRSGISRAALLRILLAMEHGNHFSLGCPHLGY
                     AAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVHPGLATLLTGPAGQKPQA"
ORIGIN      
        1 gaggggcgga cactcaggcc tggtgcgaag tactgggaga aatctgggaa cggcaaccag
       61 aggctggtcc aggagctgac cacaagccaa gagcctagga gtgcttggga ctgaaccagg
      121 gtcatggccc caccaccact actgccagtg gctgccagca ctccaatcct gcacggcgag
      181 tttggttcct acccggccaa cggcccacgg tttgccctca ccctcacaac acaagcccta
      241 cacatacagc gactacgccc aaagccagaa gcccggcccc gagatggtct agtctctctg
      301 gatgaggtct cgggctgtgg caccctgcag agccgtagcc ccgaggacac tgcagcctac
      361 ttctgcatct acacctaccc acgtggccgt cgagggggcc ggcgcagagc tacgcggacc
      421 ttccgggcgg atggggccac cacttatgag gagaatcgtg cagaggccca gcgctgggcc
      481 actgccctca cgtgtctcct ccgaggagtg cctctgtcag gggaccagga aatcacccct
      541 gaattgctgc cccggaagcc caggctgctc atattggtca atccctttgg ggggcggggc
      601 ctggcctggc agcgctgtat ggaccacgtg gtgccaatga tctctgaagc tgggctgtcc
      661 ttcaacctca tacagacaga acgacagaac catgcccgtg agctggtgca ggggttaagc
      721 ctgagtgagt gggaaggcat tgtcactgtg tctggagacg ggctgcttta cgaggtgctg
      781 aatgggctcc ttgatcggcc agactgggag gatgccgtgc ggatgcccat tggtgtcctc
      841 ccctgtggat cgggcaatgc gctagctggg gcggtgaacc atcatggcgg gtttgagcag
      901 gttgtcggtg ttgacctgtt gctcaactgc tcgcttcttc tctgccgtgg tggcagccat
      961 cctctggacc tgctctctgt gacgctagcc tcgggatccc gctgtttttc cttcctgtca
     1021 gtggcctggg gattcttgtc agatgtggac attcacagtg agcgcttcag ggccctgggc
     1081 agcgctcgat tcacactggg tgcagtgcta ggcctggcct cgttgcatac ctaccgtgga
     1141 cgcctctcct acctccccgc taccacagaa ccagccttgc ccatcccagg ccacagtctg
     1201 cctcgagcca agtcagaact agtcttggct ccagccccag cccccgccgc cacccactcg
     1261 cctctacatc gatctgtgtc tgacctgccc ctgccccttc cccagcctgc cttggtctcc
     1321 cctggctccc ctgagcccct gcctgacctg tccctcaatg gtggtggtcc agagctgact
     1381 ggagactggg gaggagctgg ggatgcacct ctgtccccag acccactgct gccttcatcc
     1441 cccaacgctc tcaaaacagc tcagctttca cccatcgctg aagggccccc agaaatgcca
     1501 gcatcttcgg ggttcctgcc tcccacccac agtgccccag aagcctctac ctggggccca
     1561 gtggaccacc tcctccctcc cctgggctct ccactgcccc aagactgggt gacaatagag
     1621 ggggagtttg tactcatgtt gggcatcttg ccgagccacc tctgcgcaga cctgatggca
     1681 gccccacatg cacgctttga tgatggcgtt gtgcacctgt gttgggtgcg gagcggcatc
     1741 tcacgggctg cacttctacg cattttgctg gccatggagc atggaaacca cttcagcctg
     1801 ggctgccccc atctgggcta tgctgcagca cgtgccttcc gccttgaacc actcacgcct
     1861 cgtggcctgc tcactgtaga tggggagtta gtggagtatg ggccaataca ggcgcaggtg
     1921 cacccaggtc tcgccacgct gctcactggg cctgcaggtc aaaagccaca agcctgaacg
     1981 agcctaaaag catggcgagt tggtggaacc agcgccccat aggctaagat ctatcattta
     2041 caggtagaag tggggcccgc actcagaact gtgaggaggg tggagagtgg tcctgaccct
     2101 cagttcccag aggacctaga ggctcgaggg tggggcctgc ctttcttgat gtccaatgat
     2161 ggggcctgga atgtatgagc tagcaaggct tcttcagctt attgaccagc cagggtttct
     2221 tcttgcctac tccggtgcct ctacttgact ggccaatcag cccttgaggg gcaggttccc
     2281 ccaggtggtc cccagatttg cactaatgtt cctcccctgg ccagttaggg atgggatgtt
     2341 ctgtgtcttg tgtgtccctc tccctagtct aaaaagcaat tgaaaaggtc tatgcaataa
     2401 aggttgttgc ttccctctag gccttcaccc cttccacccg a
//
