LOCUS       NM_028855               1060 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus spermatid maturation 1 (Spem1), mRNA.
ACCESSION   NM_028855
VERSION     NM_028855.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Bao,J., Wu,Q., Song,R., Jie,Z., Zheng,H., Xu,C. and Yan,W.
  TITLE     RANBP17 is localized to the XY body of spermatocytes and interacts
            with SPEM1 on the manchette of elongating spermatids
  JOURNAL   Mol Cell Endocrinol 333 (2), 134-142 (2011)
   PUBMED   21184802
  REMARK    GeneRIF: Interactions between RANBP17 and SPEM1, for the first
            time, point to a potential function of SPEM1 in the
            RANBP17-mediated nucleocytoplasmic transport.
REFERENCE   2  (bases 1 to 1060)
  AUTHORS   Bao,J., Zhang,J., Zheng,H., Xu,C. and Yan,W.
  TITLE     UBQLN1 interacts with SPEM1 and participates in spermiogenesis
  JOURNAL   Mol Cell Endocrinol 327 (1-2), 89-97 (2010)
   PUBMED   20558241
  REMARK    GeneRIF: Interactions between UBQLN1 and SPEM1 suggest a role in
            the regulation of protein ubiquitination during spermiogenesis.
REFERENCE   3  (bases 1 to 1060)
  AUTHORS   Zheng,H., Stratton,C.J., Morozumi,K., Jin,J., Yanagimachi,R. and
            Yan,W.
  TITLE     Lack of Spem1 causes aberrant cytoplasm removal, sperm deformation,
            and male infertility
  JOURNAL   Proc Natl Acad Sci U S A 104 (16), 6852-6857 (2007)
   PUBMED   17426145
  REMARK    GeneRIF: Proper cytoplasm removal is a genetically regulated
            process requiring the participation of Spem1, a protein exclusively
            expressed in the cytoplasm of elongated (steps 14-16) spermatids in
            the mouse testis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EF120626.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048760.1, EF120626.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.89 cM"
     gene            1..1060
                     /gene="Spem1"
                     /gene_synonym="1700095G12Rik"
                     /note="spermatid maturation 1"
                     /db_xref="GeneID:74288"
                     /db_xref="MGI:MGI:1921538"
     exon            1..209
                     /gene="Spem1"
                     /gene_synonym="1700095G12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..998
                     /gene="Spem1"
                     /gene_synonym="1700095G12Rik"
                     /note="sperm maturation 1"
                     /codon_start=1
                     /product="spermatid maturation protein 1"
                     /protein_id="NP_083131.1"
                     /db_xref="CCDS:CCDS36199.1"
                     /db_xref="GeneID:74288"
                     /db_xref="MGI:MGI:1921538"
                     /translation="MAMAERPRPGWASYQNPNINNCQDMGNSILLLLGLIVCINIGIN
                     LVTLLWSRIRILLHRMFHIICEKETSTSLGKLVQPLRKQTYPKVHLRCTMDPVKMTVT
                     PPPTRRRYRHRAPPSRRARCPIAWAPDTDDEKPPHQHPAICSRHWNDSKDWEGFQSMQ
                     EVWEPWTQDGLEQPPQTIRFQPAVEARPLKSEIRSDQGLEAYVYTVNPPPPSPEALSH
                     KNNAAGSGGCVEGEQAQGQPVSPSFLGPANVPEIPRRHSSGRIVYDARDVRRRLRELT
                     QEVEALSHCYPLVSGSSAAEGTGKDWVYRPLKGR"
     exon            210..267
                     /gene="Spem1"
                     /gene_synonym="1700095G12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            268..1031
                     /gene="Spem1"
                     /gene_synonym="1700095G12Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1012..1017
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spem1"
                     /gene_synonym="1700095G12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1031
                     /gene="Spem1"
                     /gene_synonym="1700095G12Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggctagtgg gcattagggg tagtgggctg ggggcctaag ggccctggtg gccctaggga
       61 ccaccatggc catggctgag cggcctcggc ctgggtgggc ctcgtatcaa aaccccaaca
      121 tcaacaactg ccaggacatg ggaaactcca ttctgctgct cttgggtctt atcgtctgta
      181 ttaacattgg catcaatttg gtgaccctgc tctggagccg aatccgcatc ctcttacacc
      241 gaatgttcca tatcatttgt gaaaaagaaa ccagtacttc acttgggaag ctggtccagc
      301 ccttgaggaa gcagacctac cccaaagtcc atcttcgatg taccatggac cctgtgaaga
      361 tgactgtgac ccccccaccc actcgtcgtc gttaccgcca tcgagcgcct ccatctcgcc
      421 gtgcccgctg ccccatagct tgggcccctg atactgatga tgagaaacct ccacatcagc
      481 accctgcaat ctgttcccgc cactggaatg actctaagga ttgggaaggc tttcaatcta
      541 tgcaggaggt gtgggaacct tggactcagg atggtctaga gcaacctccc cagaccatcc
      601 gcttccagcc agcagtagag gccaggcctc tcaaatcgga aatccggtca gaccagggcc
      661 tagaggccta tgtgtatact gtaaatcctc cacctcccag tccagaggct ttgagccata
      721 aaaacaatgc ggcagggtca gggggatgtg ttgagggtga gcaagcacag ggccagcctg
      781 tctcaccatc ctttctgggt ccagcaaatg tccctgaaat accccggcgc cattcatcag
      841 gccgaatagt ctatgatgcc cgagatgtga ggagaaggtt acgagaactc acccaggagg
      901 tggaggctct gtcccactgt taccccttgg tctctggatc cagcgcagct gaggggacag
      961 gcaaagattg ggtgtatcgt cccctgaagg gaaggtgact ggggacaaaa aaataaaaaa
     1021 taaaaaagag aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
