LOCUS       NM_029485                721 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus spermatogenesis associated 24 (Spata24), transcript
            variant 2, mRNA.
ACCESSION   NM_029485
VERSION     NM_029485.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 721)
  AUTHORS   Sun,J., Lu,Y., Nozawa,K., Xu,Z., Morohoshi,A., Castaneda,J.M.,
            Noda,T., Miyata,H., Abbasi,F., Shawki,H.H., Takahashi,S.,
            Devlin,D.J., Yu,Z., Matzuk,R.M., Garcia,T.X., Matzuk,M.M. and
            Ikawa,M.
  TITLE     CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or
            epididymis-enriched genes individually dispensable for male
            reproductiondagger
  JOURNAL   Biol Reprod 103 (2), 183-194 (2020)
   PUBMED   32588039
REFERENCE   3  (bases 1 to 721)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 721)
  AUTHORS   Pitulescu,M.E., Teichmann,M., Luo,L. and Kessel,M.
  TITLE     TIPT2 and geminin interact with basal transcription factors to
            synergize in transcriptional regulation
  JOURNAL   BMC Biochem 10, 16 (2009)
   PUBMED   19515240
  REMARK    GeneRIF: TIPT2 synergizes with geminin and TBP in the activation of
            TATA box-containing promoters.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 721)
  AUTHORS   Brancorsini,S., Davidson,I. and Sassone-Corsi,P.
  TITLE     TIPT, a male germ cell-specific partner of TRF2, is
            chromatin-associated and interacts with HP1
  JOURNAL   Cell Cycle 7 (10), 1415-1422 (2008)
   PUBMED   18418073
  REMARK    GeneRIF: TIPT, a male germ cell-specific partner of TRF2, is
            chromatin-associated and interacts with HP1.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU961109.1, BC060950.1 and BM569619.1.
            
            On Oct 26, 2007 this sequence version replaced NM_029485.1.
            
            Transcript Variant: This variant (2) contains additional coding
            exons at the 3' end compared to transcript variant 1, and encodes a
            longer isoform (2) with a different C-terminus compared to isoform
            1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060950.1, BU962062.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                BU961109.1         4-50
            48-564              BC060950.1         1-517
            565-698             BM569619.1         7-140               c
            699-721             BC060950.1         652-674
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.2 cM"
     gene            1..721
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /note="spermatogenesis associated 24"
                     /db_xref="GeneID:71242"
                     /db_xref="MGI:MGI:1918492"
     exon            1..175
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..676
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /note="isoform 2 is encoded by transcript variant 2;
                     testis protein T6441 homolog; spermatogenesis-associated
                     protein 24; TATA-binding protein-like factor-interacting
                     protein; TLF-interacting protein; TRF2-interacting protein
                     in testis"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 24 isoform 2"
                     /protein_id="NP_083761.1"
                     /db_xref="CCDS:CCDS29146.1"
                     /db_xref="GeneID:71242"
                     /db_xref="MGI:MGI:1918492"
                     /translation="MATPLGWSQGGSGSVCLAFDQLRDVIESQEELIHQLRNVMVLQD
                     ENFVSKEEFHEIEKKLVEEKAAHAKTKALLAKEEEKLQFALGEVEVLSKQLEKEKMAF
                     EKALSSVKSRVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQ
                     NFRNHISDFRIQKQQETYMAQVLDQKRKKATGMRRARSRQCSREK"
     exon            176..241
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /inference="alignment:Splign:2.1.0"
     exon            242..372
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /inference="alignment:Splign:2.1.0"
     exon            373..443
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /inference="alignment:Splign:2.1.0"
     exon            444..546
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /inference="alignment:Splign:2.1.0"
     exon            547..702
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      672..677
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /note="hexamer: AATAAA"
     polyA_site      702
                     /gene="Spata24"
                     /gene_synonym="2700012K08Rik; 4930583E11Rik;
                     5133400G04Rik; TIPT; TIPT2"
                     /note="major polyA site"
ORIGIN      
        1 ggcgacggat gaggcgcgca gcaggaggcc atttccaacg agccagcggg ggcaaaagat
       61 ggcgacgccc cttgggtggt cgcagggggg ctctggatca gtgtgtctcg ccttcgatca
      121 actgcgggac gtgattgaat ctcaggagga acttatccac cagctgagga atgtgatggt
      181 tctccaggat gagaattttg tcagtaaaga agaattccat gaaatagaga agaaactggt
      241 ggaggagaaa gctgctcatg ccaaaaccaa agccctcctg gccaaggaag aagagaagtt
      301 acagtttgct ctgggagagg tggaggtgct gtccaagcag ctggagaaag agaagatggc
      361 ctttgaaaaa gcgctctcca gtgtcaagag cagagtcctg caggagtcca gcaagaagga
      421 ccagctcatc accaagtgca atgaaattga atcccacatt ataaagcaag aagatatact
      481 taatggcaaa gagaatgaga ttaaagagtt gcagcaggtt atcagccagc agaaacagaa
      541 tttcaggaat cacatatctg acttccggat ccaaaagcag caggagacct acatggccca
      601 ggtgctggat cagaagcgta agaaagccac aggaatgcgt cgggcccgta gccgtcagtg
      661 ttccagggag aaataaactg ctggttatct tcctgttctc taaaaaaaaa aaaaaaaaaa
      721 a
//
