LOCUS       NM_001395754            1113 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus sperm acrosome developmental regulator (Spacdr), mRNA.
ACCESSION   NM_001395754
VERSION     NM_001395754.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1113)
  AUTHORS   Wu,Y., Zhang,Z., He,C. and Deng,Q.
  TITLE     Testis-Specific Gene C7orf61 Is Involved in Mouse Sperm-Egg Fusion
  JOURNAL   Urol J 21 (5), 348-355 (2024)
   PUBMED   38863317
  REMARK    GeneRIF: Testis-Specific Gene C7orf61 Is Involved in Mouse
            Sperm-Egg Fusion.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1113)
  AUTHORS   Ekim Ustunel,B., Friedrich,K., Maida,A., Wang,X., Krones-Herzig,A.,
            Seibert,O., Sommerfeld,A., Jones,A., Sijmonsma,T.P., Sticht,C.,
            Gretz,N., Fleming,T., Nawroth,P.P., Stremmel,W., Rose,A.J.,
            Berriel-Diaz,M., Bluher,M. and Herzig,S.
  TITLE     Control of diabetic hyperglycaemia and insulin resistance through
            TSC22D4
  JOURNAL   Nat Commun 7, 13267 (2016)
   PUBMED   27827363
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1113)
  AUTHORS   Canterini,S., Carletti,V., Nusca,S., Mangia,F. and Fiorenza,M.T.
  TITLE     Multiple TSC22D4 iso-/phospho-glycoforms display idiosyncratic
            subcellular localizations and interacting protein partners
  JOURNAL   FEBS J 280 (5), 1320-1329 (2013)
   PUBMED   23305244
REFERENCE   4  (bases 1 to 1113)
  AUTHORS   Jones,A., Friedrich,K., Rohm,M., Schafer,M., Algire,C., Kulozik,P.,
            Seibert,O., Muller-Decker,K., Sijmonsma,T., Strzoda,D., Sticht,C.,
            Gretz,N., Dallinga-Thie,G.M., Leuchs,B., Kogl,M., Stremmel,W.,
            Diaz,M.B. and Herzig,S.
  TITLE     TSC22D4 is a molecular output of hepatic wasting metabolism
  JOURNAL   EMBO Mol Med 5 (2), 294-308 (2013)
   PUBMED   23307490
  REMARK    Erratum:[EMBO Mol Med. 2013 Jun;5(6):965]
REFERENCE   5  (bases 1 to 1113)
  AUTHORS   Canterini,S., Bosco,A., Carletti,V., Fuso,A., Curci,A., Mangia,F.
            and Fiorenza,M.T.
  TITLE     Subcellular TSC22D4 localization in cerebellum granule neurons of
            the mouse depends on development and differentiation
  JOURNAL   Cerebellum 11 (1), 28-40 (2012)
   PUBMED   20878296
REFERENCE   6  (bases 1 to 1113)
  AUTHORS   Canterini,S., Bosco,A., De Matteis,V., Mangia,F. and Fiorenza,M.T.
  TITLE     THG-1pit moves to nucleus at the onset of cerebellar granule
            neurons apoptosis
  JOURNAL   Mol Cell Neurosci 40 (2), 249-257 (2009)
   PUBMED   19084601
REFERENCE   7  (bases 1 to 1113)
  AUTHORS   Fiol,D.F., Mak,S.K. and Kultz,D.
  TITLE     Specific TSC22 domain transcripts are hypertonically induced and
            alternatively spliced to protect mouse kidney cells during osmotic
            stress
  JOURNAL   FEBS J 274 (1), 109-124 (2007)
   PUBMED   17147695
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125063.4.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-287               AC125063.4         124021-124307       c
            288-620             AC125063.4         123300-123632       c
            621-1113            AC125063.4         117555-118047       c
FEATURES             Location/Qualifiers
     source          1..1113
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
     gene            1..1113
                     /gene="Spacdr"
                     /note="sperm acrosome developmental regulator"
                     /db_xref="GeneID:122152370"
                     /db_xref="MGI:MGI:7523879"
     exon            1..287
                     /gene="Spacdr"
                     /inference="alignment:Splign:2.1.0"
     CDS             231..863
                     /gene="Spacdr"
                     /codon_start=1
                     /product="sperm acrosome developmental regulator"
                     /protein_id="NP_001382683.1"
                     /db_xref="GeneID:122152370"
                     /db_xref="MGI:MGI:7523879"
                     /translation="MVMRFLRWIRQIWRKVPSWVPFWKHLGKPGTSEQHEKRPLTGPE
                     KASMDSDTVKLVKPHKEAMVADLDAGPGMLEPCVLPSAKERSPVRDQESRSNRDSRDS
                     RSLMTLVHSVSMFMFSMLQSGWRLCRWKSSMSAGSVSSHTRTRSALGTSEAEMLREVY
                     LVLWVIRKQLRELARRQERRRRRRMWSHPSHTSRHSEPVQGLKHDARSPL"
     exon            288..620
                     /gene="Spacdr"
                     /inference="alignment:Splign:2.1.0"
     exon            621..1113
                     /gene="Spacdr"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1089..1094
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spacdr"
                     /note="hexamer: AATAAA"
     polyA_site      1113
                     /gene="Spacdr"
                     /note="major polyA site"
ORIGIN      
        1 ctacttgact cctctccctg tcccagggag gggaggaagg gcctgtcatg agtcattggg
       61 gggtacgccc cttttggatt tcgtatttct tccttcgata ctgtgcttga agcgtcgcag
      121 tacccatagt cctctctggt ggtggcactg gctcatagcc tttcccctcc tacgcctcaa
      181 atgctcgctt tgtgccaaac tttggacttg tggtgtcaag agagattgcc atggtcatga
      241 ggttcttgag atggatcagg caaatttggc gaaaggtgcc cagttgggtc ccgttctgga
      301 aacacctagg caagccaggc acgtccgagc agcacgagaa gcgtccattg acaggaccgg
      361 agaaggcttc catggactct gacactgtaa agttggtcaa gccccacaaa gaggccatgg
      421 tcgccgacct ggatgcgggc ccagggatgc tcgaaccctg tgtgctgccc tcagccaagg
      481 aaagatctcc tgtgcgtgat caagagagcc gttcgaatcg tgacagccgt gacagccgtt
      541 ctctgatgac cctagttcac tcagtctcta tgttcatgtt ctccatgcta cagtccggct
      601 ggcgactatg taggtggaag tcttctatga gtgctggctc agtttcctcc cacacgagga
      661 ccaggtcggc attggggacg tcagaggctg agatgctgcg ggaagtgtac ctggtgctct
      721 gggtcatccg caaacaacta agagagctgg cccgcaggca ggagaggcga agacggcgcc
      781 gtatgtggtc tcatccctcc catacttccc gtcactctga accagtgcag ggcctcaaac
      841 atgatgcccg aagtcctctt taggcagggg agccccagat cctttgaaag cccccacctc
      901 actcttacgg aagattgaca ggaagggttc aatggccatc aggccagagc tactggtgag
      961 gagacattcg accatactgc cacatctcac tggagcccca agaccaggcc tggggtcgaa
     1021 cacactcccc ttctctgtgt ttattcaatt tgtaaaaaaa aaaaaaaaaa aaaaaattaa
     1081 tattgagaaa taaataccgg atatttctga gta
//
