LOCUS       NM_001324545             988 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus sperm autoantigenic protein 17 (Spa17), transcript
            variant 2, mRNA.
ACCESSION   NM_001324545 XM_006510123
VERSION     NM_001324545.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 988)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 988)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 988)
  AUTHORS   Turner,L.M., Chuong,E.B. and Hoekstra,H.E.
  TITLE     Comparative analysis of testis protein evolution in rodents
  JOURNAL   Genetics 179 (4), 2075-2089 (2008)
   PUBMED   18689890
REFERENCE   4  (bases 1 to 988)
  AUTHORS   Zeng,M., Sun,H., Chen,S., Wang,X., Yang,Y., Liu,Y., Tao,D.,
            Yang,Z., Zhang,S. and Ma,Y.
  TITLE     Identification of target messenger RNA substrates for mouse RBMY
  JOURNAL   Mol Hum Reprod 14 (6), 331-336 (2008)
   PUBMED   18492746
  REMARK    GeneRIF: mRBMY protein can bind to the testis and sperm-specific
            spa17 mRNA.
REFERENCE   5  (bases 1 to 988)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Spa17 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
REFERENCE   6  (bases 1 to 988)
  AUTHORS   Frayne,J. and Hall,L.
  TITLE     A re-evaluation of sperm protein 17 (Sp17) indicates a regulatory
            role in an A-kinase anchoring protein complex, rather than a unique
            role in sperm-zona pellucida binding
  JOURNAL   Reproduction 124 (6), 767-774 (2002)
   PUBMED   12530914
REFERENCE   7  (bases 1 to 988)
  AUTHORS   Wen,Y., Richardson,R.T., Widgren,E.E. and O'Rand,M.G.
  TITLE     Characterization of Sp17: a ubiquitous three domain protein that
            binds heparin
  JOURNAL   Biochem J 357 (Pt 1), 25-31 (2001)
   PUBMED   11415432
REFERENCE   8  (bases 1 to 988)
  AUTHORS   Dong,G., Loukinova,E., Smith,C.W., Chen,Z. and Van Waes,C.
  TITLE     Genes differentially expressed with malignant transformation and
            metastatic tumor progression of murine squamous cell carcinoma
  JOURNAL   J Cell Biochem Suppl 28-29, 90-100 (1997)
   PUBMED   9589353
REFERENCE   9  (bases 1 to 988)
  AUTHORS   Kong,M., Richardson,R.T., Widgren,E.E. and O'Rand,M.G.
  TITLE     Sequence and localization of the mouse sperm autoantigenic protein,
            Sp17
  JOURNAL   Biol Reprod 53 (3), 579-590 (1995)
   PUBMED   7578682
  REMARK    Erratum:[Biol Reprod 1995 Nov;53(5):1239]
REFERENCE   10 (bases 1 to 988)
  AUTHORS   Richardson,R.T., Yamasaki,N. and O'Rand,M.G.
  TITLE     Sequence of a rabbit sperm zona pellucida binding protein and
            localization during the acrosome reaction
  JOURNAL   Dev Biol 165 (2), 688-701 (1994)
   PUBMED   7525387
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160125.2.
            
            On Aug 8, 2022 this sequence version replaced NM_001324545.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA463733.1, SRR14777531.1043171.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-463               AC160125.2         58014-58476         c
            464-646             AC160125.2         56590-56772         c
            647-717             AC160125.2         52371-52441         c
            718-795             AC160125.2         50547-50624         c
            796-988             AC160125.2         48048-48240         c
FEATURES             Location/Qualifiers
     source          1..988
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 20.78 cM"
     gene            1..988
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /note="sperm autoantigenic protein 17"
                     /db_xref="GeneID:20686"
                     /db_xref="MGI:MGI:1333778"
     exon            1..463
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /inference="alignment:Splign:2.1.0"
     exon            464..646
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /inference="alignment:Splign:2.1.0"
     CDS             493..942
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /note="band 34; sperm protein 17"
                     /codon_start=1
                     /product="sperm surface protein Sp17"
                     /protein_id="NP_001311474.1"
                     /db_xref="CCDS:CCDS22982.1"
                     /db_xref="GeneID:20686"
                     /db_xref="MGI:MGI:1333778"
                     /translation="MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFE
                     NLLEKREKTSFDPAEWGAKVEDRFYNNHAFKEQEQVEKCEQELAKSSGREETPVTPFE
                     ESTEEEREQEEAAALKIQSLFRGHVAREEVKKMKSDKNENLKEEADN"
     exon            647..717
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /inference="alignment:Splign:2.1.0"
     exon            718..795
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /inference="alignment:Splign:2.1.0"
     exon            796..988
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      988
                     /gene="Spa17"
                     /gene_synonym="Sp17"
                     /note="major polyA site"
ORIGIN      
        1 agtacgcgaa accatcagcg gcgcggcgcg gcgcggcgca gggcgctccc ctcccggcct
       61 ccgtagttaa aaaaaaaaga aaaaagaaaa aagaaaaaaa aaaacggtta cccagcaacg
      121 agataaaaca ctggaaccat ccgcaccagc ttgaagagaa agaagaggtg aggcagtttc
      181 ccccactccc tctccaatgt ggaggcttcg ccattttcct tcgtgccgta gtctctccgc
      241 atctccaata ctcccgcaac tcctggacca gacagagagc ctggcaagcc ctttctcgga
      301 gaatctggaa cgctaggtct ttggcgtccc gcccacggtt tgacctgctt cccctcgaca
      361 gcctgtcctc ccccgcccgg ttcagggctt tacacagctc tcaagattcg atatctaatc
      421 tgctgtttgt ggccaaaaga gagaaaggga agagactcca caggtaccat ataggcaatt
      481 ctttccgagg agatgtcgat tcctttctcc aacacccact accgaattcc acaaggattt
      541 ggaaatcttc ttgaagggct gacacgggag attctgaggg agcaaccgga caatatacca
      601 gcttttgccg cagcgtattt tgagaacctt ctagagaaaa gagagaaaac cagctttgat
      661 ccagcagaat ggggggctaa ggtagaggac cgcttctata acaaccacgc attcaaggaa
      721 caagaacaag ttgagaaatg tgaacaagaa ttagctaagt catctggaag agaagaaaca
      781 ccagtcactc ccttcgagga gtctactgag gaagaaagag aacaggagga ggcggctgct
      841 ctcaaaatcc agtccctctt ccggggacac gtggctagag aagaggtaaa gaagatgaag
      901 tcagataaga atgagaatct gaaagaagag gcagacaatt gagaccacag gttttacccc
      961 ccgaaacatg aaaagtaatc caaatcca
//
