LOCUS       NM_001409583            3680 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus trans-acting transcription factor 9 (Sp9), transcript
            variant 2, mRNA.
ACCESSION   NM_001409583 XM_036162341
VERSION     NM_001409583.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3680)
  AUTHORS   Cheffer,A., Garcia-Miralles,M., Maier,E., Akol,I., Franz,H.,
            Srinivasan,V.S.V. and Vogel,T.
  TITLE     DOT1L deletion impairs the development of cortical
            parvalbumin-expressing interneurons
  JOURNAL   Cereb Cortex 33 (19), 10272-10285 (2023)
   PUBMED   37566909
REFERENCE   2  (bases 1 to 3680)
  AUTHORS   Govek,K.W., Chen,S., Sgourdou,P., Yao,Y., Woodhouse,S., Chen,T.,
            Fuccillo,M.V., Epstein,D.J. and Camara,P.G.
  TITLE     Developmental trajectories of thalamic progenitors revealed by
            single-cell transcriptome profiling and Shh perturbation
  JOURNAL   Cell Rep 41 (10), 111768 (2022)
   PUBMED   36476860
REFERENCE   3  (bases 1 to 3680)
  AUTHORS   Shang,Z., Yang,L., Wang,Z., Tian,Y., Gao,Y., Su,Z., Guo,R., Li,W.,
            Liu,G., Li,X., Yang,Z., Li,Z. and Zhang,Z.
  TITLE     The transcription factor Zfp503 promotes the D1 MSN identity and
            represses the D2 MSN identity
  JOURNAL   Front Cell Dev Biol 10, 948331 (2022)
   PUBMED   36081908
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3680)
  AUTHORS   Li,Z., Shang,Z., Sun,M., Jiang,X., Tian,Y., Yang,L., Wang,Z.,
            Su,Z., Liu,G., Li,X., You,Y., Yang,Z., Xu,Z. and Zhang,Z.
  TITLE     Transcription factor Sp9 is a negative regulator of D1-type MSN
            development
  JOURNAL   Cell Death Discov 8 (1), 301 (2022)
   PUBMED   35773249
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3680)
  AUTHORS   Su-Feher,L., Rubin,A.N., Silberberg,S.N., Catta-Preta,R., Lim,K.J.,
            Ypsilanti,A.R., Zdilar,I., McGinnis,C.S., McKinsey,G.L.,
            Rubino,T.E. Jr., Hawrylycz,M.J., Thompson,C., Gartner,Z.J.,
            Puelles,L., Zeng,H., Rubenstein,J.L.R. and Nord,A.S.
  TITLE     Single cell enhancer activity distinguishes GABAergic and
            cholinergic lineages in embryonic mouse basal ganglia
  JOURNAL   Proc Natl Acad Sci U S A 119 (15), e2108760119 (2022)
   PUBMED   35377797
REFERENCE   6  (bases 1 to 3680)
  AUTHORS   Sahara,S., Kawakami,Y., Izpisua Belmonte,J.C. and O'Leary,D.D.
  TITLE     Sp8 exhibits reciprocal induction with Fgf8 but has an opposing
            effect on anterior-posterior cortical area patterning
  JOURNAL   Neural Dev 2, 10 (2007)
   PUBMED   17509151
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 3680)
  AUTHORS   Zembrzycki,A., Griesel,G., Stoykova,A. and Mansouri,A.
  TITLE     Genetic interplay between the transcription factors Sp8 and Emx2 in
            the patterning of the forebrain
  JOURNAL   Neural Dev 2, 8 (2007)
   PUBMED   17470284
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 3680)
  AUTHORS   Long,J.E., Garel,S., Alvarez-Dolado,M., Yoshikawa,K., Osumi,N.,
            Alvarez-Buylla,A. and Rubenstein,J.L.
  TITLE     Dlx-dependent and -independent regulation of olfactory bulb
            interneuron differentiation
  JOURNAL   J Neurosci 27 (12), 3230-3243 (2007)
   PUBMED   17376983
REFERENCE   9  (bases 1 to 3680)
  AUTHORS   Suske,G., Bruford,E. and Philipsen,S.
  TITLE     Mammalian SP/KLF transcription factors: bring in the family
  JOURNAL   Genomics 85 (5), 551-556 (2005)
   PUBMED   15820306
REFERENCE   10 (bases 1 to 3680)
  AUTHORS   Kawakami,Y., Esteban,C.R., Matsui,T., Rodriguez-Leon,J., Kato,S.
            and Izpisua Belmonte,J.C.
  TITLE     Sp8 and Sp9, two closely related buttonhead-like transcription
            factors, regulate Fgf8 expression and limb outgrowth in vertebrate
            embryos
  JOURNAL   Development 131 (19), 4763-4774 (2004)
   PUBMED   15358670
  REMARK    GeneRIF: Sp8 and Sp9, via Fgf8, are involved in mediating the
            actions of Fgf10 and Wnt/beta-catenin signaling during vertebrate
            limb outgrowth.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL954713.11.
            
            On Jul 20, 2022 this sequence version replaced XM_036162341.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10662774.1663896.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-695               AL954713.11        6474-7168
            696-1033            AL954713.11        13763-14100
            1034-3680           AL954713.11        15134-17780
FEATURES             Location/Qualifiers
     source          1..3680
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 43.52 cM"
     gene            1..3680
                     /gene="Sp9"
                     /note="trans-acting transcription factor 9"
                     /db_xref="GeneID:381373"
                     /db_xref="MGI:MGI:3574660"
     exon            1..695
                     /gene="Sp9"
                     /inference="alignment:Splign:2.1.0"
     exon            696..1033
                     /gene="Sp9"
                     /inference="alignment:Splign:2.1.0"
     CDS             1013..2467
                     /gene="Sp9"
                     /note="buttonhead-like zinc finger transcription factor
                     Sp9"
                     /codon_start=1
                     /product="transcription factor Sp9"
                     /protein_id="NP_001396512.1"
                     /db_xref="GeneID:381373"
                     /db_xref="MGI:MGI:3574660"
                     /translation="MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAK
                     GGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGSLAGGSGAANSAFCLASTSPTSSAFS
                     SDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYK
                     SGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLG
                     TYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAA
                     AAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSC
                     HIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRF
                     ACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGV
                     SAARAAAAAAAAAAAAAAAASAGGKEAATGPNDS"
     exon            1034..3680
                     /gene="Sp9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3389..3394
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sp9"
                     /note="hexamer: ATTAAA"
     polyA_site      3408
                     /gene="Sp9"
     regulatory      3661..3666
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sp9"
                     /note="hexamer: ATTAAA"
     polyA_site      3680
                     /gene="Sp9"
                     /note="major polyA site"
ORIGIN      
        1 gacactctgt acggtccagt gaaggatgct gagccgggtg ccaagaggtg gagaggccca
       61 gcccttactg ccacaagcca tccggctaga ccttctagag ggtttttgga gagatctaag
      121 cgtctgggac cgaaactgca ggggtgtttc tgaagctctg agtctgactc tctacgttgt
      181 cacctgcctt aaggccatcc tgcttgactg atgcctggtt ggaaactaga atgggcgtcc
      241 ctggcatgtg ctcggcgagt gtgtccgtgt cagcaagtca gcaagagtat cttttgctac
      301 ggtactagga aggagggaag aagcaagatg ccggtgccta aagcgagtgg agcctctctc
      361 tacccccatg ccattcaata ccagggagaa agtgagactc aagcgcctct cactgagctc
      421 taaggacaca ggatgtacag tgggtggtga aacagaaggc cggcccacca ggattgggct
      481 ctagactggc tggaatccag aagcatggat ttgtctgggc aatgtcacag gggcacttga
      541 gtcctcacag ggaatctcat ggcctacaca atcagcctcc ctcctccccc ttctctgcct
      601 cttggagttg caggtccttg agaagagatt ccaggcagga gaggactgaa ggaactactg
      661 agagaactca gcagggtgcc atctggagaa ataagcccgc ccccctccca cccacgcccg
      721 cagacttgac tggcacgcgc caggagcccg ggctcgggcc cctcggagcg tctgattggc
      781 tgcggggcag ctcccgtctg ctctgcctgc gccctcattg ggcgagaggc gcagccagcg
      841 gcacttcaaa gcgggtgctc ctcgcactta ggctgagttt tgccggcggg agcccagagt
      901 ccgctcggcg cgagcgcggg acgcgggagc cgcgcgggac ctgaatcgtg attcccagca
      961 gccgccaggc ttaacaccgc tccgggcctc gccgcgcagc ccaaaacctg ctatggccac
     1021 gtctatactt ggggaagagc cacgcttcgg aacgaccccg ttggccatgc tggcggcgac
     1081 ctgcaacaag atcggcaaca cgagccccct gacgaccctg cccgagtcca gcgccttcgc
     1141 caaaggcggc ttccacccct ggaagcgctc ctcgtccagc tgcaacctcg gctccagtct
     1201 ctccggcttc gctgtggcca cgggcggccg cggctcgggc agcctggcgg gtggctcggg
     1261 agccgccaac agcgccttct gcctggcctc cacgtccccc acgtcgtccg ccttcagcag
     1321 cgactatggc ggccttttct ccaactcggc ggcggcggcg gccgcggcgg ccggcgtgtc
     1381 cccgcaggag gcgggcggcc agtcggcctt catctccaag gtgcacacga cggcggccga
     1441 cggtctgtac ccgcgcgtgg gcatggcgca cccgtacgag tcgtggtaca agtcgggctt
     1501 ccactcgacc ctagcggcgg gcgaggtgac caacggcgcg gcgtcatcgt ggtgggacgt
     1561 gcacagcagc cctgggtcct ggctggaggt gcagaacccc gccggggggc tgcagagctc
     1621 gctgcactcg ggcgcccccc aggcctcgct gcactctcag ctgggcacct acaaccccga
     1681 cttcagctcg ctcacgcact cggccttcag ctccaccggc ctcggctcgt cggccgccgc
     1741 cgcttcgcac ctgctctcca ccagccagca cctgctggcc caggacggct tcaagccggt
     1801 gctgccctct tactcggact ccagcgcagc ggtggccgcg gcggccgcca gcgctatgat
     1861 ttcgggcgca gcggcggccg ccgccggggg cagctcggcg cgctccgccc gtcgctactc
     1921 gggccgcgcc acctgcgact gccccaactg ccaggaggcc gagcggctgg gtccggccgg
     1981 ggcgagccta cgccgcaagg ggctgcacag ctgtcacatc ccgggctgtg gcaaggtgta
     2041 cggcaagacg tcgcacctga aggcgcacct gcgctggcac acgggcgagc ggcccttcgt
     2101 gtgcaactgg ctcttctgcg gcaagcgctt cacgcgctcg gacgagctgc agcggcacct
     2161 gcggactcac acgggcgaga agcgcttcgc ctgccctgtg tgcaacaagc gtttcatgcg
     2221 cagcgaccac ctgagcaaac acattaagac gcacaacggg ggcggcgggg gcaaaaaggg
     2281 cagcgacagt gacacggacg ccagcaacct ggagacaccc cgttccgagt ccccggacct
     2341 catcctgcac gattccggcg tcagtgcagc ccgggcggct gcggcggcgg cagcggcggc
     2401 ggcggcagcg gcagcggcgg cttcggcggg aggcaaggaa gctgcgaccg gtcccaacga
     2461 ctcctagagg ttggcggaga ggcgcgagcg agcaagtaga gacacccaga gcgagcgagc
     2521 gagaggttcg gagggcgagc gagtgggcgc acgggagggc aggggctcca gagaagcccc
     2581 cggagcccag gctgggagcg aggtggagca gcgcggaacc ccgggcggtg gcttgctggc
     2641 ggcgccggag ttgccctcaa cccgttgcgc ccagatgaga atcgatctcg aggtccagaa
     2701 acaaaagcga gccatcctcc gacataagtg caggttcaaa actacacaca cacacacaca
     2761 cacacacaca cacacacacc accccggagt cccacaaacg caagaacgca cactcccgcg
     2821 cgcgcactca caggcaccca ctcgaacaaa cttctccaga gaagagcaat acacagaaat
     2881 gtcccctccc cccactgccc actcccccca ccatcctctg tccttttctc aaaaacaaaa
     2941 aacaaaaact agctaccact cagcaaagga ctgtcagaac tttcgaatga aaacaaacga
     3001 gacctataaa aacagaccct ttgtgtggat tatattatat ataaaatctc caagtcctgc
     3061 ttgatgtcta cttacaatga gacttttttt tttttttcta aaaaaaggaa gcatcaaaaa
     3121 aggcttaagg tgagatattc aactggaagt ctagcaacag tttctctgta tttcataaca
     3181 tctgtataaa tagggttcaa aggattgtgt tctcttttat tttcttgtaa atgttcattc
     3241 gaatagtttt tttgtgaatt cctgaaattc agggagtttc tttttaattt tctgatgcac
     3301 tttgtgaaag tcagtatata tgtaaaagat atttaaaatg ttgagttacc atttcactca
     3361 aacacgtaag ttaaggtcat ctaaagaaat taaatgcgtt tatctgtatg aagagaatct
     3421 tgacatcata ttttcatttt ggtgttatta aaggactcta aacaacactc ctcctttaaa
     3481 aaaatatcct gtttccccct caataatctt taatgtggaa tcaactattt ttttttgttg
     3541 ggaaacaaat tcccttaatg ttagttgtag gcaatgaagt ttatgtgggt tgcaaaagcc
     3601 atagcacaca tacatttttt tgagaagtca aaattattta tttgtatatc aacagcaaaa
     3661 attaaatcgg gttataagaa
//
