LOCUS       NM_011446               3266 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Mus musculus SRY (sex determining region Y)-box 7 (Sox7), mRNA.
ACCESSION   NM_011446
VERSION     NM_011446.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3266)
  AUTHORS   Feng,W., Hong,N., Wu,Y., Huang,J., Zhang,Q., Liu,G., Qian,Z.,
            Chen,Y., Jin,L., Ding,X., Zhao,P., Chen,A.F. and Yu,Y.
  TITLE     Deficiency of Sox7 leads to congenital aortic stenosis via abnormal
            valve remodeling
  JOURNAL   J Mol Cell Cardiol 199, 81-94 (2025)
   PUBMED   39746830
REFERENCE   2  (bases 1 to 3266)
  AUTHORS   Trinh,L.T., Finnel,R.R., Osipovich,A.B., Musselman,J.R.,
            Sampson,L.L., Wright,C.V.E. and Magnuson,M.A.
  TITLE     Positive autoregulation of Sox17 is necessary for gallbladder and
            extrahepatic bile duct formation
  JOURNAL   Development 152 (2) (2025)
   PUBMED   39745200
REFERENCE   3  (bases 1 to 3266)
  AUTHORS   Weberling,A., Siriwardena,D., Penfold,C., Christodoulou,N.,
            Boroviak,T.E. and Zernicka-Goetz,M.
  TITLE     Primitive to visceral endoderm maturation is essential for mouse
            epiblast survival beyond implantation
  JOURNAL   iScience 28 (1), 111671 (2024)
   PUBMED   39868030
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3266)
  AUTHORS   Blucher,R.O., Lim,R.S., Ritchie,M.E. and Western,P.S.
  TITLE     VEGF-dependent testicular vascularisation involves MEK1/2
            signalling and the essential angiogenesis factors, SOX7 and SOX17
  JOURNAL   BMC Biol 22 (1), 222 (2024)
   PUBMED   39354506
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3266)
  AUTHORS   Liu,Y., Wang,X., Wang,Z., Gao,X., Xu,H., Gao,Y. and Niu,J.
  TITLE     System analysis based on weighted gene co-expression analysis
            identifies SOX7 as a novel regulator of hepatic stellate cell
            activation and liver fibrosis
  JOURNAL   FASEB J 38 (15), e23495 (2024)
   PUBMED   39126242
  REMARK    GeneRIF: System analysis based on weighted gene co-expression
            analysis identifies SOX7 as a novel regulator of hepatic stellate
            cell activation and liver fibrosis.
REFERENCE   6  (bases 1 to 3266)
  AUTHORS   Takash,W., Canizares,J., Bonneaud,N., Poulat,F., Mattei,M.G.,
            Jay,P. and Berta,P.
  TITLE     SOX7 transcription factor: sequence, chromosomal localisation,
            expression, transactivation and interference with Wnt signalling
  JOURNAL   Nucleic Acids Res 29 (21), 4274-4283 (2001)
   PUBMED   11691915
  REMARK    GeneRIF: comparison with human gene, chromosome mapping, gene
            expression, transactivation domain
REFERENCE   7  (bases 1 to 3266)
  AUTHORS   Taniguchi,K., Hiraoka,Y., Ogawa,M., Sakai,Y., Kido,S. and Aiso,S.
  TITLE     Isolation and characterization of a mouse SRY-related cDNA, mSox7
  JOURNAL   Biochim Biophys Acta 1445 (2), 225-231 (1999)
   PUBMED   10320775
REFERENCE   8  (bases 1 to 3266)
  AUTHORS   Stock,D.W., Buchanan,A.V., Zhao,Z. and Weiss,K.M.
  TITLE     Numerous members of the Sox family of HMG box-containing genes are
            expressed in developing mouse teeth
  JOURNAL   Genomics 37 (2), 234-237 (1996)
   PUBMED   8921394
REFERENCE   9  (bases 1 to 3266)
  AUTHORS   Wright,E.M., Snopek,B. and Koopman,P.
  TITLE     Seven new members of the Sox gene family expressed during mouse
            development
  JOURNAL   Nucleic Acids Res 21 (3), 744 (1993)
   PUBMED   8441686
REFERENCE   10 (bases 1 to 3266)
  AUTHORS   Denny,P., Swift,S., Brand,N., Dabhade,N., Barton,P. and Ashworth,A.
  TITLE     A conserved family of genes related to the testis determining gene,
            SRY
  JOURNAL   Nucleic Acids Res 20 (11), 2887 (1992)
   PUBMED   1614875
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB023419.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB023419.1, AK156497.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3266
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 33.34 cM"
     gene            1..3266
                     /gene="Sox7"
                     /note="SRY (sex determining region Y)-box 7"
                     /db_xref="GeneID:20680"
                     /db_xref="MGI:MGI:98369"
     exon            1..288
                     /gene="Sox7"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..1193
                     /gene="Sox7"
                     /note="mSOX7; SRY-box containing gene 7"
                     /codon_start=1
                     /product="transcription factor SOX-7"
                     /protein_id="NP_035576.1"
                     /db_xref="CCDS:CCDS27206.1"
                     /db_xref="GeneID:20680"
                     /db_xref="MGI:MGI:98369"
                     /translation="MASLLGAYPWTEGLECPALEAELSDGLSPPAVPRPSGDKSSESR
                     IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLR
                     LQHMQDYPNYKYRPRRKKQGKRLCKRVDPGFLLSSLSRDQNTLPEKNGIGRGEKEDRG
                     EYSPGATLPGLHSCYREGAAAAPGSVDTYPYGLPTPPEMSPLDALEPEQTFFSSSCQE
                     EHGHPHHLPHLPGPPYSPEFTPSPLHCSHPLGSLALGQSPGVSMMSSVSGCPPSPAYY
                     SHATYHPLHPNLQAHLGQLSPPPEHPGFDTLDQLSQVELLGDMDRNEFDQYLNTPGHP
                     DSAAGVGTLTGHVPLSQGTPTGPTETSLISVLADATATYYNSYSVS"
     exon            289..3266
                     /gene="Sox7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggtcagcg ccggccccac gaggcgaagc caagtgaccc gcgttcggcc atggcctcgc
       61 tgctgggcgc ctatccgtgg accgagggac tggagtgtcc cgccctggaa gccgagctgt
      121 cggatgggct gtcgccgccc gccgtccccc gaccttcagg ggacaagagt tcggaaagcc
      181 ggatccggcg gcccatgaat gccttcatgg tgtgggccaa ggatgagagg aaacgtctgg
      241 cagtgcagaa cccggacctg cacaacgcgg agctcagcaa gatgctggga aagtcatgga
      301 aggcgctgac actgtcccag aagagaccct atgtggatga ggcagagcgg ctgcgcctgc
      361 agcacatgca ggattacccc aactacaagt accggccccg caggaagaaa caaggcaagc
      421 gcctctgcaa gcgcgtggac cctggcttcc tcctcagctc cctctctcgt gaccagaaca
      481 cgctgcctga gaaaaacggc attggcaggg gggagaagga ggacaggggt gagtactccc
      541 caggggccac cttgcctgga ctgcacagct gctaccgcga aggtgcagct gctgcccctg
      601 gcagtgtgga cacgtatccc tacgggctgc ccacacctcc ggagatgtcg cccctggatg
      661 cgctggagcc agagcagacc ttcttctcgt cctcatgtca ggaggagcat ggtcaccccc
      721 atcacctccc ccatctacca gggccccctt actcaccgga gttcacacct agtcccctcc
      781 actgcagcca ccctctaggt tctttagccc ttggccaatc cccaggggtt tctatgatgt
      841 cctctgtttc tggatgtccc ccatctccag cctattactc ccatgccacc taccaccctc
      901 tccaccccaa cctccaggcc cacctgggcc agctgtcccc acctccggag caccctggct
      961 ttgacacctt ggatcagcta agccaggtgg aacttctggg agacatggat cgcaatgaat
     1021 ttgatcagta tttgaacact cccggccacc ctgactctgc tgcaggggtt ggaaccctca
     1081 ctgggcatgt cccgctctcc caggggactc ccacaggccc tacagagacc agcctcatct
     1141 cagtcctggc tgatgccacg gccacgtatt acaacagcta cagtgtgtca tagagctgga
     1201 ggaatggagc ctggcccagc cctgccatcc cctcctccct atgaagcact gagctgagca
     1261 gaaactgtgg cgatgccact ccttggtggc aagaggtcaa aactgctgtt ccagagcctt
     1321 ccggtcaaaa gccaggatcc agcgctcctt ctgtcccttt aaatgtgttt tgtcggcttc
     1381 atcaaggaag cacagccttg ggagctgttt gcagtaggat ttcctagccg ctctacacca
     1441 tcagtgtagc tgatgggaag aagcccagtg cattggagct cctgcttttg gtgtagctac
     1501 ttctgatctg tggtgctccc agtaagatgg accctgggcc tggggtccat ctcagttcag
     1561 tctctaactg gcaaaacccc actctggctt gaccagccct gactattctc tcctgtacag
     1621 tgagggttgg cttcatagcc aagccctcgc tctatggatc tccaagttac agccctctca
     1681 aggccaagga aagtatgaat gaatgactgc ccaaggaccc aggttttctg ctttcctata
     1741 atactgtcca cagccaccct agaattccaa agaaactcct tcagtcgaga aaaatattca
     1801 cctttggtct ggcaagatgg tgtgggatgt ctcagtgggt aagactgcct gctgccaagt
     1861 ctgatgacct acgttctata tccggagcct acatggtgga agaagagaac tgactcctgc
     1921 aagttgtatt ctgacttcca aatgcacgtg tgcccctgca ttatatgtgt gcttgagcat
     1981 gctcacatgc acacacacac acacacacac actaaatgta atttttttaa aggaaaagat
     2041 ctaccctggt tcggaaaatt aatgagtatg ttcaactgca tcactgaaag caaaatcaga
     2101 ttagaacttg ttttgttttg ttttgttttg ttttgttttg ttttgttttg ttttgttctg
     2161 agacagggtt tctctgtgta accctggctg ccctggaact cactgtgtag accaggctgg
     2221 cctcaacctc aaaagtaagc ctgcctctgc ctcctgggta ctgggattaa aggtgagtgg
     2281 caccacaccc agcctggatt tttttttaat atatacttta gatacattat ttttgttaca
     2341 tacatctcag gcgactacag tgtgagaaat gaccttatgc aggcatgcct attcccaaca
     2401 ctgtgcccca ggtgtgtacc ctgatttaga ttcttctcaa ctgtgacaat gtctcatccc
     2461 ctcatcacag aatgaaccag agagctagaa acctaaaacg tctgtccaca aaagtgttgg
     2521 ggtgtgctga tttctagagc agagctgtag catactctta tctacagatg caaaagatga
     2581 ctctctgccc aatgtctgct gccccttgct cccaggaggg cttttctctc ttctctgtta
     2641 ctctccctcc aaactggccc ctaattcaaa gggcccctcg cttggaatcc caggcaccat
     2701 tcccctgggc gtgaagggaa cttggttctt gtttctcaag tggatacatc agaacaatca
     2761 cctatcccac agtcctttgg ctgtcccaaa caaacaccct gtgacaccca aagatgtttc
     2821 tgagctttgg tcgcacccca gacatttcca ttctctaaac ctcctttgaa ggaacatacc
     2881 aaacactgag ctaacagact cttgtctgcc cttggacacg tgtatattat tgcctttatg
     2941 aaatgtgttt ttatattctg ctattatgtc caccttatat tttgtattgt tgacagatcc
     3001 ccaagaagtc ttattataat atcacttata agatatactt aatctttatg ctattactgt
     3061 atataccatt tggtaacaaa tagtgaattg ttgatgatgt aattgactgg tgcccagtcc
     3121 cggatggata ttaataatct cgtgaaacac tatcacaggc attaagctac tctgttccat
     3181 tttttcaaga aaactaaata tgcatggaac agttatgaaa ttgatttttc aaaatgttta
     3241 atttaaataa atttttttgt accttc
//
