LOCUS       NM_173384               2995 bp    mRNA    linear   ROD 21-DEC-2022
DEFINITION  Mus musculus SRY (sex determining region Y)-box 30 (Sox30), mRNA.
ACCESSION   NM_173384 XM_908145
VERSION     NM_173384.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2995)
  AUTHORS   Ho UY, Feng CA, Yeap YY, Bain AL, Wei Z, Shohayeb B, Reichelt ME,
            Homer H, Khanna KK, Bowles J and Ng DCH.
  TITLE     WDR62 is required for centriole duplication in spermatogenesis and
            manchette removal in spermiogenesis
  JOURNAL   Commun Biol 4 (1), 645 (2021)
   PUBMED   34059773
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2995)
  AUTHORS   Han F, Yin L, Jiang X, Zhang X, Zhang N, Yang JT, Ouyang WM, Hao
            XL, Liu WB, Huang YS, Chen HQ, Gao F, Li ZT, Guo QN, Cao J and Liu
            JY.
  TITLE     Identification of SRY-box 30 as an age-related essential gatekeeper
            for male germ-cell meiosis and differentiation
  JOURNAL   Aging Cell 20 (5), e13343 (2021)
   PUBMED   33721419
  REMARK    GeneRIF: Identification of SRY-box 30 as an age-related essential
            gatekeeper for male germ-cell meiosis and differentiation.
            Erratum:[Aging Cell. 2022 Nov;21(11):e13728. PMID: 36205919]
REFERENCE   3  (bases 1 to 2995)
  AUTHORS   Han F, Jiang X, Li ZM, Zhuang X, Zhang X, Ouyang WM, Liu WB, Mao
            CY, Chen Q, Huang CS, Gao F, Cui ZH, Ao L, Li YF, Cao J and Liu JY.
  TITLE     Epigenetic Inactivation of SOX30 Is Associated with Male
            Infertility and Offers a Therapy Target for Non-obstructive
            Azoospermia
  JOURNAL   Mol Ther Nucleic Acids 19, 72-83 (2020)
   PUBMED   31835093
REFERENCE   4  (bases 1 to 2995)
  AUTHORS   Planells B, Gomez-Redondo I, Pericuesta E, Lonergan P and
            Gutierrez-Adan A.
  TITLE     Differential isoform expression and alternative splicing in sex
            determination in mice
  JOURNAL   BMC Genomics 20 (1), 202 (2019)
   PUBMED   30871468
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2995)
  AUTHORS   Chen Y, Zheng Y, Gao Y, Lin Z, Yang S, Wang T, Wang Q, Xie N, Hua
            R, Liu M, Sha J, Griswold MD, Li J, Tang F and Tong MH.
  TITLE     Single-cell RNA-seq uncovers dynamic processes and critical
            regulators in mouse spermatogenesis
  JOURNAL   Cell Res 28 (9), 879-896 (2018)
   PUBMED   30061742
REFERENCE   6  (bases 1 to 2995)
  AUTHORS   Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S,
            Sachs AJ, Morrison MA, Nystuen AM, DeAngelis MM and Haider NB.
  TITLE     Genetic variations strongly influence phenotypic outcome in the
            mouse retina
  JOURNAL   PLoS One 6 (7), e21858 (2011)
   PUBMED   21779340
  REMARK    Erratum:[PLoS One. 2011;6(10).
            doi:10.1371/annotation/f375292d-9fc7-4e3c-9dc7-af0aee76fa15]
REFERENCE   7  (bases 1 to 2995)
  AUTHORS   Ballow D, Meistrich ML, Matzuk M and Rajkovic A.
  TITLE     Sohlh1 is essential for spermatogonial differentiation
  JOURNAL   Dev Biol 294 (1), 161-167 (2006)
   PUBMED   16564520
REFERENCE   8  (bases 1 to 2995)
  AUTHORS   Lioubinski O, Muller M, Wegner M and Sander M.
  TITLE     Expression of Sox transcription factors in the developing mouse
            pancreas
  JOURNAL   Dev Dyn 227 (3), 402-408 (2003)
   PUBMED   12815626
REFERENCE   9  (bases 1 to 2995)
  AUTHORS   Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic
            DB, Keck-Waggoner CL, Popescu NC and Kimura S.
  TITLE     Cloning, expression, and chromosomal localization of the mouse gene
            (Scgb3a1, alias Ugrp2) that encodes a member of the novel
            uteroglobin-related protein gene family
  JOURNAL   Cytogenet Genome Res 97 (1-2), 120-127 (2002)
   PUBMED   12438750
REFERENCE   10 (bases 1 to 2995)
  AUTHORS   Osaki E, Nishina Y, Inazawa J, Copeland NG, Gilbert DJ, Jenkins NA,
            Ohsugi M, Tezuka T, Yoshida M and Semba K.
  TITLE     Identification of a novel Sry-related gene and its germ
            cell-specific expression
  JOURNAL   Nucleic Acids Res 27 (12), 2503-2510 (1999)
   PUBMED   10359848
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY005801.1, BY716235.1 and AV255326.2.
            
            [WARNING] On Jan 11, 2024 this sequence was replaced by
            NM_173384.3.
            
            On Jun 18, 2008 this sequence version replaced NM_173384.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY005801.1, SRR7652917.1295088.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-387               AY005801.1         1-387
            388-388             BY716235.1         228-228
            389-2965            AY005801.1         389-2965
            2966-2995           AV255326.2         905-934
FEATURES             Location/Qualifiers
     source          1..2995
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 27.49 cM"
     gene            1..2995
                     /gene="Sox30"
                     /note="SRY (sex determining region Y)-box 30"
                     /db_xref="GeneID:214105"
                     /db_xref="MGI:MGI:1341157"
     exon            1..1064
                     /gene="Sox30"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..2359
                     /gene="Sox30"
                     /note="SRY-box containing gene 30"
                     /codon_start=1
                     /product="transcription factor SOX-30"
                     /protein_id="NP_775560.1"
                     /db_xref="CCDS:CCDS24570.1"
                     /db_xref="GeneID:214105"
                     /db_xref="MGI:MGI:1341157"
                     /translation="MERARPEPPPPPPPPPRQPPRPTPPRPLRPAPPAQPVEAATFRA
                     AAAERSQSPSAQATAAMAAVASSCGEAAAAGAQAAGTRRLLQVKPEQVLLLPPGGPGV
                     PPAPDEGAAAAAAAAAAAASSAQARLLQLRPELLLLPPQSAADGGPCRPELHPMQPRT
                     LLVKAEKQELGAGLDLSVGSRRTTEAGPRASRAAKLDGTGKALDGRRSDEKKAKLEAE
                     EAPRDALKGGEGKSLLAIGEGVIKTEEPDRPRDDCRLGTEATSNGLVHSSKEAILAQP
                     PSAFGPHQQDLRFPLTLHTVPPGARIQFQGPPPSELIRLSKVPLTPVPIKMQSLLEPS
                     VKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAAN
                     NAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVS
                     NVFSGTTQNIISTNPTTIYPYRSPTYSVVIPGLQNTITHPVGEAPPAIQLPTPAVQRP
                     SPITLFQPSVSSTGPVAVPPPSLTPRPSLPPQRFSGPSQTDIHRLPSGSSRSVKRSTP
                     GSLESTTRIPAGASTAHARFATSPIQPPKEYASVSTCPRSTPIPPATPIPHSHVYQPP
                     PLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLGYYE
                     DRYQKHEAIFSALNRDYPFRDYPDEHTHSEDSRSCESMDGPPYYSSHGHGGEEYLNAM
                     PTLDIGALENVFTAPASAPSGVQQVNVTDSDEEEEEKVLRNL"
     exon            1065..1304
                     /gene="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1484
                     /gene="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..1977
                     /gene="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2995
                     /gene="Sox30"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccctccccc atggagagag ccaggccgga gccaccgccg ccaccgccgc cgccgccgcg
       61 ccaaccgccg cggcccaccc ctccgcgccc gttgcgcccc gctccgcccg cgcagcccgt
      121 cgaggccgcc accttccggg ccgcggccgc agagcgctcc cagtcgccgt cggctcaggc
      181 cacggccgcc atggccgcgg tggcctcgtc gtgcggggag gccgcggcgg cgggtgcgca
      241 ggcggcaggg acgcgacgcc tgctgcaagt gaagccggaa caggtgctgc tgctgcctcc
      301 cggaggaccg ggggtgcctc cggctcccga cgagggcgca gccgccgccg ccgctgccgc
      361 tgccgccgcc gcctcgtccg cgcaggcgcg cctgctgcag ctgaggccgg agctgctgct
      421 gttgcctccg cagtccgcgg ccgacggagg cccctgcagg ccggagctgc accccatgca
      481 gccccggacg ctgctcgtca aggccgagaa gcaagagctg ggggcgggct tggacctgtc
      541 ggtgggatct cggaggacca ccgaggccgg cccgagagcc tcgagggccg ccaagttgga
      601 tggcaccggg aaggccctcg acggccgccg aagcgatgag aagaaagcca agctggaggc
      661 agaggaggct ccgagggatg cgctgaaagg cggggaaggc aagagcctgc tggccatcgg
      721 agaaggagtc atcaagacgg aggagccaga cagacccagg gacgattgta ggctgggcac
      781 ggaggccacg tccaatggcc tggtccacag cagcaaggag gccatcctgg cccagccgcc
      841 tagtgctttt gggccacacc agcaagacct aaggttccct ttgacactcc acaccgtccc
      901 acctggagcc cgtatccagt ttcaggggcc tccgccttct gagttgatac ggttgtccaa
      961 agtccccctg acaccagtgc ctattaaaat gcagtccttg ctggagcctt ctgtaaaaat
     1021 tgaaaccaaa gatgtccccc tcaccgtgct gccctcagat gcaggaatac ctgatactcc
     1081 cttcagtaag gacagaaatg gtcatgtgaa gcgacccatg aatgcattta tggtttgggc
     1141 aagaatccac cggccagcac tagccaaagc taacccagcc gccaacaatg cagaaatcag
     1201 tgtccagctc gggttagagt ggaacaaact tagtgaagaa caaaagaaac cttattatga
     1261 tgaagcacaa aagattaaag agaagcacag agaggagttt cctggttggg tttatcagcc
     1321 tcgtccaggg aagcgaaaac gcttccctct aagtgtttcc aatgtatttt ctggtaccac
     1381 acagaatatt atctctacaa atcctacaac aatttatcct tatcgctcac ctacctactc
     1441 tgtggtaatt cccggccttc agaacaccat cactcatcca gttggtgaag cccctcctgc
     1501 catccagctg cccacacctg cagtccagcg cccaagtccc atcacacttt tccagcccag
     1561 cgtctccagc actggcccag tggccgtccc gcctccaagc ctgacgcccc gcccatcact
     1621 cccacctcag cgcttttctg ggccttccca aactgacatt cataggctcc cttcgggaag
     1681 cagtcgctct gtgaagagat ccactccagg ctctctggag agcaccacca ggattccagc
     1741 tggtgcaagt actgcccatg ccagatttgc aacctcgcct atccagcctc ctaaggagta
     1801 tgccagcgtt tccacttgtc cccgaagcac tccgataccc ccggcgactc ccattccaca
     1861 ctcacacgtc tatcagcccc caccccttgg ccatccagcc acactgtttg ggacaccacc
     1921 tcggttctcc tttcatcacc cttacttcct acctggacct cattacttcc cgtcaagcac
     1981 gtgcccttat agtcggcctc cctttggcta tggaaatttt ccaagttcaa tgccagaatg
     2041 tcttggttac tatgaagaca gataccaaaa acatgaggct atcttttcag ctttaaatag
     2101 agactatcct ttcagagact atccagatga gcacacacac agtgaagact ctcggagctg
     2161 tgagagcatg gacgggcccc cttactacag cagccatggc cacggtgggg aagagtactt
     2221 gaatgccatg cccactctgg acattggagc cttggagaat gtcttcacag ccccagcctc
     2281 agccccctct ggtgtccagc aagtcaatgt cactgacagc gacgaggagg aagaagaaaa
     2341 agtgctcagg aatttatagt ttaaaatatg cgcagaaaat aaacatttct taaaatatat
     2401 tctgggtcag ttggtgtgag aaaaaaagcc tagaatgctt tgctgagtgt tttcagccat
     2461 gatctgagga gtcaggacca agtgccgttc atgtcttccc aagttctctt agtgaccctg
     2521 gactcccgat gcctcagcgt agggatctta aaatccaaag tagttacttt catggctgaa
     2581 atttgcacca acatgtgata gcattacgtt atcttggaaa attcaaaatt cagaaagctc
     2641 ctgtggcata tgaggacaca tgtgagtata tcatctgcac agcaagtgtg atatctcagg
     2701 gtacattatt ttatttttct gaaaattttt ggtgtttata tatttataga tgttgtcagt
     2761 ttttatgtaa cattttgaaa atattttgat aacttgtaga catggactag aactcagttg
     2821 ctaaatttaa tttacactaa taaccaatta taagttaaaa atgtatttta atgacaccta
     2881 gcagttcctt cagatatatt catttctgtt actgaacatt ttatcatcat tttaactatc
     2941 tttcccattt ggtatgcatt gttatattgt tgttgtaact aaataaacag atgaa
//
