LOCUS       NM_009237               2074 bp    mRNA    linear   ROD 17-DEC-2024
DEFINITION  Mus musculus SRY (sex determining region Y)-box 3 (Sox3), mRNA.
ACCESSION   NM_009237 XM_988206
VERSION     NM_009237.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2074)
  AUTHORS   Omura,S., Ogawa,R., Kawachi,T., Ogawa,A., Arai,Y., Takayama,N.,
            Masui,A., Kondo,K., Sugimoto,H., Shinohara,H.M., Takahashi,T.,
            Maeda,H. and Ohyama,K.
  TITLE     Olig2+/NG2+/BLBP+ astrocyte progenitors: a novel component of the
            neurovascular unit in the developing mouse hippocampus
  JOURNAL   Front Cell Neurosci 18, 1464402 (2024)
   PUBMED   39484182
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2074)
  AUTHORS   Rupprecht,J., Reiprich,S., Baroti,T., Christoph,C., Sock,E.,
            Frob,F. and Wegner,M.
  TITLE     Transcription Factors Sox2 and Sox3 Directly Regulate the
            Expression of Genes Involved in the Onset of Oligodendrocyte
            Differentiation
  JOURNAL   Cells 13 (11), 935 (2024)
   PUBMED   38891067
  REMARK    GeneRIF: Transcription Factors Sox2 and Sox3 Directly Regulate the
            Expression of Genes Involved in the Onset of Oligodendrocyte
            Differentiation.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2074)
  AUTHORS   Song,H. and Morrow,B.E.
  TITLE     Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle
            for inner ear development
  JOURNAL   Dev Biol 494, 71-84 (2023)
   PUBMED   36521641
REFERENCE   4  (bases 1 to 2074)
  AUTHORS   Li,B., Brusman,L., Dahlka,J. and Niswander,L.A.
  TITLE     TMEM132A ensures mouse caudal neural tube closure and regulates
            integrin-based mesodermal migration
  JOURNAL   Development 149 (17) (2022)
   PUBMED   35950911
REFERENCE   5  (bases 1 to 2074)
  AUTHORS   Sun,Y., Wang,L., Zhu,T., Wu,B., Wang,G., Luo,Z., Li,C., Wei,W. and
            Liu,Z.
  TITLE     Single-cell transcriptomic landscapes of the otic neuronal lineage
            at multiple early embryonic ages
  JOURNAL   Cell Rep 38 (12), 110542 (2022)
   PUBMED   35320729
REFERENCE   6  (bases 1 to 2074)
  AUTHORS   Collignon,J., Sockanathan,S., Hacker,A., Cohen-Tannoudji,M.,
            Norris,D., Rastan,S., Stevanovic,M., Goodfellow,P.N. and
            Lovell-Badge,R.
  TITLE     A comparison of the properties of Sox-3 with Sry and two related
            genes, Sox-1 and Sox-2
  JOURNAL   Development 122 (2), 509-520 (1996)
   PUBMED   8625802
REFERENCE   7  (bases 1 to 2074)
  AUTHORS   Rex,M., Uwanogho,D., Cartwright,E., Pearl,G., Sharpe,P.T. and
            Scotting,P.J.
  TITLE     Sox gene expression during neuronal development
  JOURNAL   Biochem Soc Trans 22 (3), 252S (1994)
   PUBMED   7821514
REFERENCE   8  (bases 1 to 2074)
  AUTHORS   Behlke,M.A., Bogan,J.S., Beer-Romero,P. and Page,D.C.
  TITLE     Evidence that the SRY protein is encoded by a single exon on the
            human Y chromosome
  JOURNAL   Genomics 17 (3), 736-739 (1993)
   PUBMED   8244390
REFERENCE   9  (bases 1 to 2074)
  AUTHORS   Wright,E.M., Snopek,B. and Koopman,P.
  TITLE     Seven new members of the Sox gene family expressed during mouse
            development
  JOURNAL   Nucleic Acids Res 21 (3), 744 (1993)
   PUBMED   8441686
REFERENCE   10 (bases 1 to 2074)
  AUTHORS   Gubbay,J., Collignon,J., Koopman,P., Capel,B., Economou,A.,
            Munsterberg,A., Vivian,N., Goodfellow,P. and Lovell-Badge,R.
  TITLE     A gene mapping to the sex-determining region of the mouse Y
            chromosome is a member of a novel family of embryonically expressed
            genes
  JOURNAL   Nature 346 (6281), 245-250 (1990)
   PUBMED   2374589
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL807233.10.
            
            On Feb 3, 2022 this sequence version replaced NM_009237.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC052024.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2074              AL807233.10        127657-129730       c
FEATURES             Location/Qualifiers
     source          1..2074
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 33.66 cM"
     gene            1..2074
                     /gene="Sox3"
                     /gene_synonym="Sox-3"
                     /note="SRY (sex determining region Y)-box 3"
                     /db_xref="GeneID:20675"
                     /db_xref="MGI:MGI:98365"
     exon            1..2074
                     /gene="Sox3"
                     /gene_synonym="Sox-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..1362
                     /gene="Sox3"
                     /gene_synonym="Sox-3"
                     /note="SRY-box containing gene 3"
                     /codon_start=1
                     /product="transcription factor SOX-3"
                     /protein_id="NP_033263.2"
                     /db_xref="CCDS:CCDS30161.2"
                     /db_xref="GeneID:20675"
                     /db_xref="MGI:MGI:98365"
                     /translation="MRPARENASGERSPRVPADFARSPSASLPFPPELPARRPLSTTP
                     TESPGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGPPTPAAGTGVPAA
                     PGAAGKSGANPAGGANAGNGGSGGANGGGGGGGGGGSDQDRVKRPMNAFMVWSRGQRR
                     KMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRK
                     TKTLLKKDKYSLPGGLLPPGAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAY
                     SLVQEQLGYAQPPSMSSPPPPPALPQMHRYDMAGLQYSPMMPPGAQSYMNAAAAAAAA
                     SGYGGMAPSAAAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASH
                     SQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI
                     "
     regulatory      2055..2060
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sox3"
                     /gene_synonym="Sox-3"
                     /note="hexamer: AATAAA"
     polyA_site      2074
                     /gene="Sox3"
                     /gene_synonym="Sox-3"
                     /note="major polyA site"
ORIGIN      
        1 aagctgcgaa tgcgaccagc tcgagagaac gcatcaggtg agagaagccc gcgagttccc
       61 gccgactttg cgcggagccc ttcggctagc ctgcccttcc cgcctgagct gccggcccgc
      121 cggcccctga gcaccactcc gacggagtcc cccggccttt tcacggtggc cgctccagcc
      181 cccggagcgc cgtctcctcc cgccacgctg gcgcacctcc ttcccgcccc ggcgatgtac
      241 agcctgctgg agactgaact caagaacccc gtggggccgc ccaccccagc cgcgggcacc
      301 ggcgtccccg cagctcccgg cgctgcaggc aagagtggcg cgaacccagc cggcggagcg
      361 aacgcaggca acgggggcag cgggggcgcg aacggcggcg gtggtggtgg tggcggcggg
      421 ggcagcgacc aggaccgcgt caagcgaccc atgaacgcgt tcatggtgtg gtcccgcggg
      481 cagcggcgca agatggccct ggagaacccc aagatgcaca actccgagat cagcaagcgc
      541 ttgggcgccg actggaaact gctgaccgat gcggagaagc ggccgttcat cgacgaggcc
      601 aagcgactgc gtgcggtgca catgaaggag tacccggact acaagtaccg gccccgccgc
      661 aagaccaaga cgctgctcaa gaaggacaag tactcgctgc ccggcggcct cctgcccccg
      721 ggcgccgccg cagccgccgc cgctgccgcc gcagccgccg ccgccagcag cccggtgggc
      781 gtgggccagc gcctggacac gtacacgcac gtgaacggct gggccaacgg cgcctactcg
      841 ctcgtgcagg agcagctggg ctacgcgcag cccccgagca tgagcagccc gccgccgcca
      901 cccgcgctgc ctcagatgca ccgctacgac atggccggcc tgcagtacag ccccatgatg
      961 ccacccggcg cccagagcta catgaacgcc gccgccgccg ctgccgccgc ctcgggctac
     1021 gggggcatgg cgccctccgc cgcggccgcc gccgccgccg cctacgggca gcagcccgcc
     1081 accgctgccg ccgcggccgc cgccgccgcc gccatgagcc tgggccccat gggctccgtg
     1141 gtgaagtcgg agcccagctc tccgccgccc gccatcgctt cgcactcgca gcgcgcgtgc
     1201 ctcggcgacc tgcgcgacat gatcagcatg tacctgccac ctggcgggga cgcggccgac
     1261 gccgcttctc cgctcccagg cggccggctg cacggcgtgc accagcacta ccagggcgcc
     1321 gggactgcgg tcaatggaac ggtgccgctg acccacatct gagctccggc ccgcgctccc
     1381 agctcttcgc ccccaccccg ccccacaccc cccacgttgg gacgccttgc tgtttagctt
     1441 tgctcgcctg ggaccgttgc cttgtaccga agatgaggag gaccgaaagt ttggccgtaa
     1501 ctgtcggggt tttgtacaaa agcgagaagt cccgagcagc ggaaatggga cttgctagag
     1561 ccgctggctt ctgaccactg cccctccctc cccctctggc tgggaatcgc tgtggtgttt
     1621 gcggagaaac cgcggcccct tcctcttccc ggattcctag gttcttctgt tgcagttgaa
     1681 aatgtcttgt tagtttgcta ttaatcgaga actgagtgag gttgcccgcc cccaagaact
     1741 gcaatgcctc cacccccagt cgtattgctt ctgttttcct ctggcttttt tttggggggg
     1801 gggtgctggc cgcgccaatt ggcgcgacag ctaaagccaa tgttaattta tagccaggtg
     1861 tgcgtgtgtt tcccgccttg ccgcccctgg ccgcgggaca gctctgtcca gtgcgcgttt
     1921 aggctgttga gtttgtgatt tctgcagtga tctatttgct atttcgtgta cgcatttcgt
     1981 tcgggtggtg gggaaggggt tattttgttc caggtttttt caaagttttg ttcttaattg
     2041 ctaagtgaga gatcaataaa ttttataacc aata
//
