LOCUS       NM_009235               1156 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus SRY (sex determining region Y)-box 15 (Sox15), mRNA.
ACCESSION   NM_009235
VERSION     NM_009235.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Planells,B., Gomez-Redondo,I., Pericuesta,E., Lonergan,P. and
            Gutierrez-Adan,A.
  TITLE     Differential isoform expression and alternative splicing in sex
            determination in mice
  JOURNAL   BMC Genomics 20 (1), 202 (2019)
   PUBMED   30871468
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1156)
  AUTHORS   Paul,A., Crow,M., Raudales,R., He,M., Gillis,J. and Huang,Z.J.
  TITLE     Transcriptional Architecture of Synaptic Communication Delineates
            GABAergic Neuron Identity
  JOURNAL   Cell 171 (3), 522-539 (2017)
   PUBMED   28942923
REFERENCE   3  (bases 1 to 1156)
  AUTHORS   Ng,C.K., Li,N.X., Chee,S., Prabhakar,S., Kolatkar,P.R. and Jauch,R.
  TITLE     Deciphering the Sox-Oct partner code by quantitative cooperativity
            measurements
  JOURNAL   Nucleic Acids Res 40 (11), 4933-4941 (2012)
   PUBMED   22344693
REFERENCE   4  (bases 1 to 1156)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   5  (bases 1 to 1156)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 1156)
  AUTHORS   Yamada,K., Kanda,H., Aihara,T., Takamatsu,N., Shiba,T. and Ito,M.
  TITLE     Mammalian Sox15 gene: promoter analysis and implications for
            placental evolution
  JOURNAL   Zoolog Sci 25 (3), 313-320 (2008)
   PUBMED   18393569
  REMARK    GeneRIF: These results suggest that the region from -297 to -8 of
            the Sox15 gene contains three distinct cis-elements, and that these
            sequences were conserved among eutherian mammals during vertebrate
            evolution.
REFERENCE   7  (bases 1 to 1156)
  AUTHORS   Miyashita,A., Shimizu,N., Endo,N., Hanyuu,T., Ishii,N., Ito,K.,
            Itoh,Y., Shirai,M., Nakajima,T., Odani,S. and Kuwano,R.
  TITLE     Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are
            clustered in a 40 kb region of mouse chromosome 11
  JOURNAL   Gene 237 (1), 53-60 (1999)
   PUBMED   10524236
REFERENCE   8  (bases 1 to 1156)
  AUTHORS   Hiraoka,Y., Ogawa,M., Sakai,Y., Taniguchi,K., Fujii,T., Umezawa,A.,
            Hata,J. and Aiso,S.
  TITLE     Isolation and expression of a human SRY-related cDNA hSOX20
  JOURNAL   Biochim Biophys Acta 1396 (2), 132-137 (1998)
   PUBMED   9540826
REFERENCE   9  (bases 1 to 1156)
  AUTHORS   Stock,D.W., Buchanan,A.V., Zhao,Z. and Weiss,K.M.
  TITLE     Numerous members of the Sox family of HMG box-containing genes are
            expressed in developing mouse teeth
  JOURNAL   Genomics 37 (2), 234-237 (1996)
   PUBMED   8921394
REFERENCE   10 (bases 1 to 1156)
  AUTHORS   van de Wetering,M. and Clevers,H.
  TITLE     Sox 15, a novel member of the murine Sox family of HMG box
            transcription factors
  JOURNAL   Nucleic Acids Res 21 (7), 1669 (1993)
   PUBMED   8479922
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK131957.1 and BU758023.1.
            
            On Jun 8, 2011 this sequence version replaced NM_009235.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU758023.1, AK131957.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1094              AK131957.1         3-1096
            1095-1156           BU758023.1         1-62                c
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11"
     gene            1..1156
                     /gene="Sox15"
                     /gene_synonym="Sox16"
                     /note="SRY (sex determining region Y)-box 15"
                     /db_xref="GeneID:20670"
                     /db_xref="MGI:MGI:98363"
     exon            1..863
                     /gene="Sox15"
                     /gene_synonym="Sox16"
                     /inference="alignment:Splign:2.1.0"
     CDS             337..1032
                     /gene="Sox15"
                     /gene_synonym="Sox16"
                     /note="protein SOX-15; SRY-box containing gene 15; SRY
                     (sex determining region Y)-box 16; protein SOX-16; SRY-box
                     containing gene 16; SRY-box transcription factor 15"
                     /codon_start=1
                     /product="transcription factor SOX-15"
                     /protein_id="NP_033261.1"
                     /db_xref="CCDS:CCDS24902.1"
                     /db_xref="GeneID:20670"
                     /db_xref="MGI:MGI:98363"
                     /translation="MALTSSSQAETWSLHPRASTASLPLGPQEQEAGGSPGASGGLPL
                     EKVKRPMNAFMVWSSVQRRQMAQQNPKMHNSEISKRLGAQWKLLGDEEKRPFVEEAKR
                     LRARHLRDYPDYKYRPRRKSKNSSTGSVPFSQEGGGLACGGSHWGPGYTTTQGSRGFG
                     YQPPNYSTAYLPGSYTSSHCRPEAPLPCTFPQSDPRLQGELRPSFSPYLSPDSSTPYN
                     TSLAGAPMPVTHL"
     exon            864..1138
                     /gene="Sox15"
                     /gene_synonym="Sox16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1117..1122
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sox15"
                     /gene_synonym="Sox16"
                     /note="hexamer: ATTAAA"
     polyA_site      1123
                     /gene="Sox15"
                     /gene_synonym="Sox16"
                     /note="major polyA site"
ORIGIN      
        1 gtagcacctg ggtgcactcc tggcagctgt tgggactttg tggagaccaa gagctgcacg
       61 cttgaaactg cagtttcaac agaagaaccc tgtctcgctg aagcagaggg tagaaagagc
      121 gactggtaga cctgagagaa cactacctct ccggtaaagg gctccagaca aggattctaa
      181 attcagcttc ccagaggtga caatcgatcg ctgggagcaa agtttggatt caagcgctct
      241 ggaagatact taagtaccca aatattccta gtccagtctt cgctctggga gaagggcatt
      301 caagacgccc tctcaaagag gcttcacctc caacccatgg cgctgaccag ctcctcacaa
      361 gcagagactt ggagcctgca tcctcgggct tccacggcct ctttgccttt aggaccccag
      421 gagcaggagg ccggcgggag ccctggagcg tctgggggac ttccgctgga gaaggtgaag
      481 cggcccatga acgccttcat ggtgtggagc tctgttcagc gccgccagat ggcgcagcag
      541 aaccccaaga tgcacaactc tgagatctcc aagcgcttgg gcgctcagtg gaagctgctg
      601 ggcgatgaag agaagcgacc cttcgtggag gaggctaagc gtcttcgtgc ccgccacctc
      661 cgcgactatc ccgactacaa gtaccgaccc cggcgtaaga gcaaaaactc gagcaccggg
      721 tctgtcccct ttagccaaga aggaggtggc ctggcatgtg gtggctcaca ctgggggcca
      781 gggtacacaa ctacccaagg gagcagaggc tttgggtacc agccccccaa ctattcgaca
      841 gcctacctgc ctggcagtta cacctcttcc cactgcagac cggaggcccc cttaccatgc
      901 accttccctc agagtgatcc caggctccag ggggagctaa gaccctcttt ctccccttac
      961 ctatccccag actcttccac tccatataat acttcccttg ctggagcccc catgccagta
     1021 acccaccttt aactggcagg gacgcccagg gccaacccca cagaccccta cagatctcca
     1081 aggaaccaga atgcacacta aacacaattt tgtacaatta aaaccatgtt tcggagtcaa
     1141 aaaaaaaaaa aaaaaa
//
