LOCUS       NM_001024560            1695 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus sorting nexin 32 (Snx32), transcript variant 1, mRNA.
ACCESSION   NM_001024560
VERSION     NM_001024560.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1695)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB597960.1, BC048922.1 and AI846187.1.
            
            On Mar 31, 2018 this sequence version replaced NM_001024560.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048922.1, SRR1660821.152917.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                BB597960.1         2-29
            29-1678             BC048922.1         1-1650
            1679-1695           AI846187.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1695
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.34 cM"
     gene            1..1695
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /note="sorting nexin 32"
                     /db_xref="GeneID:225861"
                     /db_xref="MGI:MGI:2444704"
     exon            1..185
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..1361
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /note="isoform 1 is encoded by transcript variant 1;
                     sortin nexin-6B; sorting nexin-6B"
                     /codon_start=1
                     /product="sorting nexin-32 isoform 1"
                     /protein_id="NP_001019731.1"
                     /db_xref="CCDS:CCDS29468.1"
                     /db_xref="GeneID:225861"
                     /db_xref="MGI:MGI:2444704"
                     /translation="MEEQHQEAGNESKPSSTSVDLQGDSPLQVEISDAVSERDKVKFT
                     VQTKSGLPHFAQSEFSVVRQHEEFIWLHDTYVENEEYAGLIIPPAPPRPDFEASREKL
                     QKLGEGNSSITREEFSKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFSV
                     FLEYSQDLSVREKNRKEVLGGLLRSIVRSADEVLITGISGLKEVDDFFEHERTFLVEY
                     HTRIRDTCQRADRVMHSHKCLADNYIPISAALSSLGTQEVNQLKRSFLKLAELFERLR
                     KLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNRE
                     VRPAESRQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLL
                     LQNTLVALKGEP"
     exon            186..290
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            291..401
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            402..523
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            524..647
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            648..752
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            753..858
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            859..934
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            935..974
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1061
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1221
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1307
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..1682
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1657..1662
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /note="hexamer: AATAAA"
     polyA_site      1682
                     /gene="Snx32"
                     /gene_synonym="B930037P14Rik; Snx6b"
                     /note="major polyA site"
ORIGIN      
        1 gtgggcaatg ggacccaccc agggaggccg cagctagtgt caatgtcagc tgatagcatc
       61 cctacaaggt tccctcaccc aagctcttgg aacgcgcagg ccgtggcttg tcgtaggatt
      121 cctgtatatc ccagctaagg agcaccatgg aggagcaaca tcaggaagct ggaaatgaga
      181 gtaagccttc ctccacgtca gtggatctgc agggggacag tcccttacag gtggagattt
      241 ctgatgcagt gagtgagcgg gacaaggtga agttcactgt tcaaaccaag agtggcctcc
      301 ctcactttgc ccagtctgag ttctcagtgg ttcgccagca cgaagagttc atctggctac
      361 atgacaccta tgtggaaaac gaagagtacg ccggcctcat cattccccca gcccctccca
      421 ggccagactt tgaggcttca agggaaaagc tgcagaagtt gggtgagggc aacagctcca
      481 tcacccggga agaattctcc aagatgaagc aggagctaga agcggaatac ttggccatct
      541 ttaagaagac tgttgcgatg catgaagtct tcctgcagcg cctggcagcc catcccaccc
      601 tgcgtcggga ccacaacttc tccgtcttct tggaatacag ccaggatctg agtgttcgag
      661 agaagaacag gaaggaggtc ttgggagggc tcctgaggag catcgtcagg tctgcagatg
      721 aagtcctcat caccggcata tcagggctca aggaggtaga tgacttcttt gagcacgaga
      781 ggaccttcct agtagaatac cacacccgaa tccgagacac ctgccagagg gccgaccgtg
      841 ttatgcactc ccacaagtgc ctggcagaca actatatccc tatctctgct gcactgagca
      901 gtctcggaac ccaggaagtc aaccaactca agaggagctt cctgaagctg gcagagctct
      961 ttgaacggct gagaaaactg gaaggccggg tagcctctga tgaggacctg aagctgtctg
     1021 acatgctgag atattacatg cgagactcac aggcagccaa ggacctgttg taccggcggc
     1081 ttcgggcact ggctgactac gagaatgcta acaaggcact ggacaaagct cggactagga
     1141 accgagaagt acggccagca gagagccgcc aacagctgtg ctgccagcgc ttcgagcgcc
     1201 tctctgactc cgccaaacaa gagctcatgg acttcaagtc tcgcagggtc tcctctttcc
     1261 gtaagaatct cattgagctg gccgaactgg agctcaagca cgccaaggcc agcaccctgc
     1321 ttctccagaa cacccttgtt gcccttaagg gagagcctta gtgaaaccag acacttcact
     1381 gacagctgtc ctgtctcctg ccttctccct ataaagacgc tctcctttcc taccatgggg
     1441 gccacttgcc acacccttac tcttgcttgg gcaaacccag gcccaaaagc agttggctct
     1501 gcctgacagg gaagtatggg gggaccatag gtaagcagag ttctagggac cctagccctc
     1561 tttacagcag gctgtctgtc aaagctccag accgccatcc tgccactggc tttagaagag
     1621 ttcgttggca ccccaccccc acacctgctc ctcacaaata aacagccggt ttactgccac
     1681 aaaaaaaaaa aaaaa
//
