LOCUS       NM_172468               7507 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus sorting nexin family member 30 (Snx30), mRNA.
ACCESSION   NM_172468
VERSION     NM_172468.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7507)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   2  (bases 1 to 7507)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147437.1, BB645079.1 and AL831738.4.
            
            On Jan 11, 2006 this sequence version replaced NM_172468.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147437.1, AK029012.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-453               AK147437.1         3-455
            454-576             BB645079.1         265-387
            577-4341            AK147437.1         579-4343
            4342-7507           AL831738.4         98705-101870
FEATURES             Location/Qualifiers
     source          1..7507
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 32.81 cM"
     gene            1..7507
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /note="sorting nexin family member 30"
                     /db_xref="GeneID:209131"
                     /db_xref="MGI:MGI:2443882"
     exon            1..576
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             421..1734
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /note="novel PX domain containing protein"
                     /codon_start=1
                     /product="sorting nexin-30"
                     /protein_id="NP_766056.1"
                     /db_xref="CCDS:CCDS18226.1"
                     /db_xref="GeneID:209131"
                     /db_xref="MGI:MGI:2443882"
                     /translation="MAGGPPKALPSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLL
                     MARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDIDGEARDLFVTVDDPKKHV
                     CTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFV
                     VKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIAL
                     LSRVGESVKHVTGGYKLRSRPLEFAAISDYLDTFALKLGTIDRIAQRIIKEEIEYLVE
                     LREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYVLYS
                     DSMKGVLKKRDQVQAEYEAKLEAVALRKEERPKVPADVEKCQDRMECFNADLKADMER
                     WQSNKRHDFRQLLVGLADKNIQYYEKCLMAWESIIPLLQEKQETK"
     exon            577..768
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            769..879
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1038
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1234
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1434
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1521
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1674
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1675..7507
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      7199
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /note="major polyA site"
     regulatory      7473..7478
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      7507
                     /gene="Snx30"
                     /gene_synonym="4732481H14Rik; C030041J06Rik"
                     /note="major polyA site"
ORIGIN      
        1 tttctgcgtg tgcagtgtgg ctggaagatc ctaactcaca ctgatgcttt ctgagccccc
       61 agcgaagctg ccagtgggcg cacttcctgc cgggaggtgg gcggggcggg ccgcctcctc
      121 cttcaagctc cgccccaccc tgcgtcccgc cctccctccc ggcgggcaga ggctccgcgg
      181 gggcggggct gagagccgtg ggcggcgtgg cgctgctagc agggcgcagg gtcggaggtg
      241 ctggggtttg gcgcggctta gcccacggag ctgtggtgta acgctcggga aagctcagcc
      301 tcgcgggcag gagaagcatc gggcggaggc tgccaccacc agctagtgca gggcctcggg
      361 ccgagtgggg cggagagctg cgggagtaag cggcggcccg ggtcccgagc gctgcgcgcc
      421 atggcgggcg ggccccccaa ggccctgccg tccacggggc cccagtcctt gcgcgacatg
      481 ccgcacccgc tagccggctc cagcagcgag gaggccgtgg gaggcgacag cacgcccagc
      541 ccggacctac tgatggcccg cagcttcggt gacaaggatc tcatcttgcc caacggtggt
      601 actccagcag gcactgccag cccagcttct tcatcttccc ttctgaacag acttcagctt
      661 gatgatgaca ttgatggtga agccagagat ctctttgtca cagttgatga tcctaagaag
      721 cacgtctgca caatggagac ctacatcaca tacaggatca ccaccaaaag cacacgggtg
      781 gagtttgact tgccagaata ttctgttcgt cggcgatacc aggatttcga ctggctgagg
      841 aacaaactgg aagagtcgca gcccactcat ctcattcccc cgcttcctga gaagtttgtg
      901 gtgaagggtg ttgtggatcg cttctcagaa gagtttgtgg agaccagaag aaaagcgctg
      961 gacaaattcc taaaaaggat tacagatcac cccgtgctct ctttcaatga acacttcaat
     1021 gtgttcctca ctgctaagga cctgaatgcc tacaagaagc aagggatagc attgctgagc
     1081 agagtgggtg agtcagtcaa gcacgtcacc ggaggctata agctgaggag tcggcctctg
     1141 gagtttgcgg ccatcagcga ctacttagac acttttgcac tcaaactggg aaccatcgat
     1201 cggatagccc agcggatcat caaggaagaa atagagtacc tggtagagct gagggagtac
     1261 gggcctgtgt attccacctg gagcgccttg gaaggcgagc tggccgagcc cctggaggga
     1321 gtgtcagcct gcattgggaa ctgctccaca gccttggaag agctgacaga tgacataaca
     1381 gaagagtttc tgcctgtgct cagggaatac gttctgtact ctgactccat gaagggtgta
     1441 ttgaagaaga gggaccaagt tcaagcagag tacgaagcca aactggaagc tgtggctctg
     1501 aggaaggaag agcgtcccaa ggtgccagca gatgtggaga agtgccagga taggatggag
     1561 tgcttcaacg ctgacctgaa ggctgatatg gagaggtggc agagcaacaa gcggcacgac
     1621 ttccggcagc tgctcgtggg cttggctgac aagaatatcc agtattatga gaagtgcctc
     1681 atggcgtggg agtccattat tccactactg caagagaagc aagagactaa gtaggttttg
     1741 gaacagagac tcttctgcct ccacagggca tggaaccctg aaccagaatg tccctgcagt
     1801 gccggagagg tcgccgtggg aaaacagcac aacagcacct cttgtgtgtg tactttctac
     1861 ccccgccccc agttgttttc agttagtatt tattccttgg agtctatgag actgtaatca
     1921 tctctcagca gcatacctcc gtattgtgaa ggaacctctt aaatggaaca ctaaaagact
     1981 tgaaactgag gggcaagata acccccacat gacacgtgac atcactttgg ggacagccca
     2041 gttgccattg tgggacagaa ccccagtcct gcgtttcagg gacatgggga gacatgaaga
     2101 aggcagctgc agcttgctgt ggagaccccg tggctctgca ctttacccgt gagggcatta
     2161 acctgaccca gcatggaagg aggtgtgggt accttctcag aaagtcctta atttacagtg
     2221 gcctgtagcc tgtggccgtg gccgtggctg tggcctgctg cctgctcatg atgagtggcc
     2281 tctgttgact tgtttctggt tcacgtgggg ccacctgaat ccgtgtctgt gagcattgac
     2341 gcttgagtga gcacgccagc gtccttgtcc ttatgggatg cctcaggatc ttgtttctga
     2401 caccagaatg caacagatga gaagcttttt ggtgtgaact ggaaaaaaaa aaaaggtgca
     2461 tttttctccg tgaaggtctt agtgtatgtg ttttgcttgt taactgtcat cgtggttggg
     2521 attagacctg tttggaaaca gctgctgtca gtgatgctcc ggtgtgccaa gccccagctc
     2581 cgatgtctgc tttgtgcaat ttgcctttac ctcaccaaaa atgtctagtt taatcttcct
     2641 gccgtgcccg ctgactgtct gggcagcctt gcagtggggg ctgatgtgct gtcttatttt
     2701 tgctgtcaca atttgtaaac tcagtgtgac ttctatatga gtgttttaac cctcagcatt
     2761 ctgtggtcag gaagataaaa gcatctgcag gtccctccaa gacgagaaga gcaacatcat
     2821 gctctttgct tctgtctatg tggaaatctc cgtttgcagc caaaatctgg gggctgccac
     2881 tgtacttaac atcttcattt gaagcctttc agatttccat aaagccagca atcagaaagg
     2941 atctctcttc cataccactg ttcttgctaa aaggaagctg catatttgtg ttctttcatc
     3001 tgtggctctt tgctaaaaat ccgtagatct gagctgcagg taaacggaag gggcgtcgtt
     3061 gtctttaagg tgaggcggcc aagcactgct ccgtatataa gttaatttgt aaatccggag
     3121 cagacggcat gctaagtcct gtaattccct ctaacattga gtcagataca tcatgggaca
     3181 tcatgggatg gcagctagat agcatgaaac aatttatctt ctcatatttg acaaatttgt
     3241 gatagaaata ataattccca catctaccgg tacttgccta aaccctgact gtgccatccc
     3301 aaaggccttg atgtgaattt tctttggtac aaataggaat ggcccactga ggcagaggag
     3361 taagagtggt ccatacaccc aaatgccagc aaattggcat ctcattctac ctctaaacca
     3421 ctgggttggt atgggtatga atgctcagag ctcacccgag catgctggta gagtcagggt
     3481 gtgtatttag tcaccaaccg gcctccattg tgtgtatcag caaacaccag actcgctcag
     3541 aggtgatgtc catctttgag aaacatgaag ctttgctttg tggattgtat gcctgatatg
     3601 atgaatagtc atgtgatgat acatgggaag aactatagaa agaattatcc agaagctaag
     3661 atttgatggc cagctggttg ccaaaacctc aagtcaatcc tgtgtgctgg ttagttatgc
     3721 aagaagaaag ccccgtagaa acagcctcca gctgcactgg gagacgtagg gagggaagca
     3781 gggtccacag ccattccctc atgagaggtg gctctcatgg catcttgcaa tgtttgtctt
     3841 gttttgttca tttggccagt aaggaatgtc cctgggcttt gagtttccag aaagagatgg
     3901 aataatggag actttctttc cctggggacc agtgtcagtg gcagagccag ggacacccat
     3961 gcacaaggag gcatgcttgc ccttctcctt gggatggcag ctggtgagct gaggaggctg
     4021 gcctagagga aaaaaggcag cagacagtga agaggccttc ctccctccct gctccacagg
     4081 ccccctcagt ccctgggaaa gtatgcacaa aagagactcc ctacatagct cagagactac
     4141 agtgccaaaa tgccccagag aggctccatt acttctggag cctacaaagc tgttccctga
     4201 tgtcacaggt ccctccgact cattttccag gagactttgc cttgagggtg ccacaggtgg
     4261 agagataaag atagcttttg aagcttgaac acatgccagt gagatgaaag ttggccttag
     4321 caactgccca ggtcctgaga aatggagggc ttgttcatgg ggttagaaac ctgcaaaggc
     4381 agccgggcgt ggtggcgcat gcctttaatc ccagcactcg ggaggcagag gcaagcggat
     4441 ttctgagttt gaggccaacc tggtctacaa agtgagttcc aggacagcca gggctacaca
     4501 gagaaacttc gtctcgcaaa accaaaacca aaaccaccac caacaacaaa aaacaaaagt
     4561 ccaaaaaacc aaaaaaccta caaaggcaaa agaggtttga gagccgtggt tgtttaggac
     4621 agttgtggtt tgtagcagga aaggacactc ctgatgttgg gaatttgcaa gaagaatctg
     4681 ggctgagctg cttcaaacaa ggaggctttg ctctggagtg aggagggagt gacccctcag
     4741 cctgtgtagg gtccagtttt atgctctcgg aaggctcagc agtgattgct gccgagtggg
     4801 aagtagcttc tcccagctgt tcctcacctc accagatatt ttcccaaagc cgaaacaaga
     4861 aaagtcagca tgcctggggc tagaagcgga atgtaagata cgtctctatg ccaaatggag
     4921 ttgtagaatg taccctctca gcccataaac aggaggaaac catatgtgaa cactacagcc
     4981 tctggcgagg gctctgtgga gattttaatt ttagaagggg gcatgatggc agtgtttctc
     5041 ttttaggaca acacccacgg aacactcaaa ggctgtgtga cttgtcctgt cctgtggcac
     5101 cgaagcccta ggtagctggc tgttttgatg aggtcatttg aatcatggga gtgtccttac
     5161 actacactat cctgagctgg ttggggtggg tagaagaagg caaggactgc ctgagaggct
     5221 gcgttgaccc tactgatgtg ggtcttggga tgggctggaa cagggttcct gcctgagtag
     5281 gtggaactgg caaccttgaa gggtgattcc cccccacccc cagaggatca gctgcctgtg
     5341 gttgggacag ggcacaccac cttccctcag acggtcttgc taagtatatg actgggagag
     5401 tttggtcatt tttgtgtacc ctatggtggg aatgtggggt tgcctttcaa aagccttcag
     5461 gatggcaaca gattggatgt gctatctcag tgcctgcagg tctctctgct cgaggcagca
     5521 gggggcgctt tgcagtatag ttgaggaaaa tgaccgctcc ttgaccaaac tgagatgcac
     5581 ttggtgtgtg ggaactgatt gcttcctccc tgtttataat tcagtgaata atcacgggcc
     5641 caatatttta ctaacccact ctgtaggttg tcagtgttcc attttgaaag tgtccccgtg
     5701 gttgcacact tcagaggaca gggactctgt gtgtctaaga aggctgggat gagggctctg
     5761 ttacagggca gactgttctc tcatagtctt atctgtttga atattcctgg gtatgacttt
     5821 atgtgtggca aaaacccaca ttaccaaagt agtttttaac tactgtaatt tgtaaataag
     5881 tgttgtggca ggtgggaacc tttaaaagat cagtaagatg tttctcatat ttatgaactt
     5941 agcacttgaa aaccaacaca ctcagaaaaa gccacagatt gttaaaagcc taattgtagt
     6001 tcgtaacaat ttgtcagtac gtactaattg ccttattctt cagctagtgg tttataaaga
     6061 ggctgcatag aaagttttac acatggaagc agctgatgta gagacttcat ataggcagct
     6121 gcagtcctaa agtctcaagc tagagggtgg gggccacgga aggaaggcag cctttcaggt
     6181 agcaagatta aatattgctg ttgccaaata gtatttgaaa taataccaga aaacggggac
     6241 cacagtactg ttcgatgttt tcaagtgaga aagaggaatg tagtatgctt tggcatagtt
     6301 tgggagtgga gaatacagac attatcagca gtgacaaatc acatagcttc aaaaactcct
     6361 ccagtttgtg acaacatgac aggtgtgaca gcatgacagg tttgctctgc ttctgcagag
     6421 tgggccccag aggtcactta ggactgagat gctccaaagt ttgaagtgcc aaataacatg
     6481 aaacgtgctc tgtcgactca atattaaagc cagggtgaag agttgcaaac ccctctgtcc
     6541 ctgcagtact gcctgagtgt gtggtgattc tgggctctcc acaaccagct caaagcagct
     6601 agcacccgtg ctcactgttg ttggacgggc tggtccacag cctcagaccc acgctctgcc
     6661 gagatactgg acgggaggaa ggatttttcc tagactgcgg attggcgtga caaagcaatg
     6721 gctgtgtcag ctgggccttc atccaggaac agaccaacat aaaccagcat cttctaccag
     6781 ttagcactgt cctcctggac catgctgagg gttgggcctc tccctcagag tcctttctca
     6841 ctgtagttct gtgtgcctgt tcccttcatg cctgagtcag gaatacatgg agagacagcc
     6901 tacatctgac agactcccac aaaacaaact gccagcaaac tttctaactc attttaaccg
     6961 ttcaagcggg gaattaaaac aaacttttgg actatttttt tttaattgtt ctttatgttt
     7021 aaaacttgca gagatagaag caggcttctg aggtacgggg tcttgctgtg tgctctctct
     7081 ccgtgctgcc gttaagccaa aacaaaagct gtgaacatag gtgcttgaga gaatgcgtgt
     7141 tgacaggaaa gtgactgatt tacagaccca agtctttgtc tcatgaaact accaaaaaag
     7201 aatgtcacct tttttctttg ttgtggaacc agagattata aaaaggaaaa aaaaggaaaa
     7261 aaaaaagttg tcttgttgta tttttgatgc tggcacaagg ttcttgtcca ctttggtttt
     7321 tcttatctct gtatgtaaga aattctgttt gttgtttact atggaattag tattacattt
     7381 tgaggtaaac aaagaatttg tattgcttga taaactatta gcttgtaaat taaaattttt
     7441 ttctttacct cagttaactt aagtaatgga ccaataaacc tatcaaagct gcttcatttc
     7501 ttccgga
//
