LOCUS       NM_027840               1434 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus sorting nexin 20 (Snx20), mRNA.
ACCESSION   NM_027840
VERSION     NM_027840.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1434)
  AUTHORS   Clairfeuille,T., Norwood,S.J., Qi,X., Teasdale,R.D. and
            Collins,B.M.
  TITLE     Structure and Membrane Binding Properties of the Endosomal
            Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins
            SNX20 and SNX21
  JOURNAL   J Biol Chem 290 (23), 14504-14517 (2015)
   PUBMED   25882846
  REMARK    GeneRIF: SAXS solution structures of SNX20 and SNX21 show that the
            proteins adopt a compact globular architecture; membrane
            interaction analyses indicate the presence of phosphoinositide
            -binding sites that may regulate their intracellular localization.
REFERENCE   2  (bases 1 to 1434)
  AUTHORS   Schaff,U.Y., Shih,H.H., Lorenz,M., Sako,D., Kriz,R., Milarski,K.,
            Bates,B., Tchernychev,B., Shaw,G.D. and Simon,S.I.
  TITLE     SLIC-1/sorting nexin 20: a novel sorting nexin that directs
            subcellular distribution of PSGL-1
  JOURNAL   Eur J Immunol 38 (2), 550-564 (2008)
   PUBMED   18196517
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC126054.5.
            
            On Apr 30, 2007 this sequence version replaced NM_027840.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK018632.1, AK157032.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849377,
                                           SAMN00849388 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AC126054.5         232783-232925       c
            144-282             AC126054.5         228566-228704       c
            283-434             AC126054.5         226711-226862       c
            435-1434            AC126054.5         223625-224624       c
FEATURES             Location/Qualifiers
     source          1..1434
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 43.51 cM"
     gene            1..1434
                     /gene="Snx20"
                     /gene_synonym="9130017C17Rik"
                     /note="sorting nexin 20"
                     /db_xref="GeneID:71607"
                     /db_xref="MGI:MGI:1918857"
     exon            1..143
                     /gene="Snx20"
                     /gene_synonym="9130017C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            144..282
                     /gene="Snx20"
                     /gene_synonym="9130017C17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..1103
                     /gene="Snx20"
                     /gene_synonym="9130017C17Rik"
                     /codon_start=1
                     /product="sorting nexin-20"
                     /protein_id="NP_082116.1"
                     /db_xref="CCDS:CCDS22512.1"
                     /db_xref="GeneID:71607"
                     /db_xref="MGI:MGI:1918857"
                     /translation="MASPEHPGSPGWRGPINQCRTRTRQEVLPPGPDLPCPGPEEAQD
                     GPSSNSSMTTRELQEHWQKEKSRWKHVRLLFEIASARIEERKVSKFVMYQVVVIQTGS
                     FDSDKAVVERRYSDFERLQKALLKRFGPELEDVAFPRKRLTGNLSAETICERRRELRE
                     YLRLLYAVRAVRRSREFLDFLTRPELREAFGCLRAGQYARALELLGRALPLQEKLTAH
                     CPSAAVPALCAALVCLRDLERPAEAFAVGERALRCLRTRENHRYYAPLLDAMVRLAYA
                     LGKDFAALQSRLDENQLRRPTHRDATLKELTVREYLS"
     exon            283..434
                     /gene="Snx20"
                     /gene_synonym="9130017C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            435..1434
                     /gene="Snx20"
                     /gene_synonym="9130017C17Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cactcagccc atttcctgtt ttcaaaagga gaactcagga ttgcggcaga cattcagcca
       61 tctagttgga ccttgcaaaa agagatcgga ctggggcatg tgactctcct ggaccccgaa
      121 cccacaaagc ctgaagatcc cagctcaggt agccttggag catggcaagt ccagagcatc
      181 ctgggagccc tggctggaga ggacccataa accaatgcag aacaaggacc agacaggaag
      241 tattgccccc aggcccagac ctcccatgtc caggaccaga agaagcccaa gatggcccca
      301 gctctaactc cagcatgacc acaagggaac tccaggaaca ctggcagaag gagaagagcc
      361 gctggaaaca tgtcaggctg ctctttgaga tcgcctcagc ccgcatagag gagaggaaag
      421 tctccaagtt tgtgatgtac caagtcgtgg tcatccagac cgggagcttc gacagcgaca
      481 aggcggtggt ggaacggcgc tactcggact tcgagaggct gcagaaggcc ctcctcaagc
      541 gcttcgggcc ggagctggag gacgtggcgt tcccgcggaa gcgcctgacc gggaacctgt
      601 cggccgagac catctgcgag cggcgccggg agctgcgcga gtacctgcgg ctgctttacg
      661 ccgtgcgcgc cgtgcgccgc tcgcgcgagt tcctcgactt cctcacgcgg cccgagctgc
      721 gcgaggcctt cggctgcctg cgcgccggcc agtacgcgcg cgcgctcgag ctgctgggcc
      781 gcgcgctgcc gctgcaggag aagctgacgg cgcactgccc gagcgccgcc gtgcccgcgc
      841 tttgcgccgc gctcgtctgc ttgcgcgacc tcgagcggcc ggccgaggcc ttcgcagtcg
      901 gcgagcgcgc gctgcgatgc ctgcggacgc gcgagaacca ccgctactac gcgccactgc
      961 tggacgccat ggtgcgcctg gcctacgcgc tgggcaagga cttcgcggcg ctgcagagcc
     1021 gcctggacga gaaccagctc cggaggccca cgcacaggga cgccaccctg aaggagctca
     1081 cggtgcggga gtatctgtcc tgaggcggcc cgacaggtgc cctggcatcc aggctgcgca
     1141 gacagtgtcg tgggtcgcca tcgcctgggg gctttgctgg acggctttgg acaagcctgg
     1201 cttgaggggc tcctgggacc tctggaagag ccatcttgtg acccttgagt gccaggttct
     1261 ctaaatccta agccgacaag ctcagctatc aaaactttgc aagtactatg gaccttacgt
     1321 gccatctcgg aatgggaagg acttgcctac cgcacagaat gtgttcaagg ccagcctaaa
     1381 aagtttgctg agactggctc caaataaaga ggtctgagga tgtgacttaa tggc
//
