LOCUS       NM_130796               4466 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus sorting nexin 18 (Snx18), mRNA.
ACCESSION   NM_130796
VERSION     NM_130796.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4466)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4466)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4466)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 4466)
  AUTHORS   Nakazawa,S., Gotoh,N., Matsumoto,H., Murayama,C., Suzuki,T. and
            Yamamoto,T.
  TITLE     Expression of sorting nexin 18 (SNX18) is dynamically regulated in
            developing spinal motor neurons
  JOURNAL   J Histochem Cytochem 59 (2), 202-213 (2011)
   PUBMED   21339182
  REMARK    GeneRIF: SNX18 may play an active role in axonal elongation
REFERENCE   5  (bases 1 to 4466)
  AUTHORS   Thornhill,P.B., Cohn,J.B., Drury,G., Stanford,W.L., Bernstein,A.
            and Desbarats,J.
  TITLE     A proteomic screen reveals novel Fas ligand interacting proteins
            within nervous system Schwann cells
  JOURNAL   FEBS Lett 581 (23), 4455-4462 (2007)
   PUBMED   17761170
REFERENCE   6  (bases 1 to 4466)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC063089.1, BC137801.1 and BP763454.1.
            
            On Jun 18, 2009 this sequence version replaced NM_130796.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC063089.1, AF408408.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                BC063089.1         1-23
            24-4146             BC137801.1         10-4132
            4147-4466           BP763454.1         27-346              c
FEATURES             Location/Qualifiers
     source          1..4466
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 64.0 cM"
     gene            1..4466
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /note="sorting nexin 18"
                     /db_xref="GeneID:170625"
                     /db_xref="MGI:MGI:2137642"
     exon            1..1763
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..2017
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /note="sorting nexin-associated Golgi protein 1; sorting
                     nexin associated golgi protein 1"
                     /codon_start=1
                     /product="sorting nexin-18"
                     /protein_id="NP_570614.2"
                     /db_xref="CCDS:CCDS36784.1"
                     /db_xref="GeneID:170625"
                     /db_xref="MGI:MGI:2137642"
                     /translation="MALRARALYDFKSENPGEISLREHEVLSLCSEQDIEGWLEGINS
                     RGDRGLFPASYVQVIRAPEPGPPADGGPGAPARYANVPPGGFEPLPAAPPAAFPPLLQ
                     PQASPGSFQPPGAGFPYGGGALQPSPQQLYGGYQASLGSDDDWDDEWDDSSTVADEPG
                     ALGSGAYPDLDGSSSAGGGAAGRYRLSTRSDLSLGSRGVSAPPAHQASGAKSSATVSR
                     NLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTK
                     QTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGR
                     FEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDE
                     MVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTG
                     FKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDP
                     VMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISF
                     ATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKYDSV"
     exon            1764..4447
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3814
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /note="major polyA site"
     polyA_site      4324
                     /gene="Snx18"
                     /gene_synonym="Snag1"
     regulatory      4422..4427
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /note="hexamer: AATAAA"
     polyA_site      4447
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /note="major polyA site"
ORIGIN      
        1 cgagttgcag tcgctgctgc gagccgagcc gagctgcacg gagggcgaga gcggagcggg
       61 gagcggaccg gtgcgctgcc ctccaggctt cccttcggcg ttcggggggg ggatcctgac
      121 tgcaggggcc ctcggaccgg cccgagctcg gggcgccggg ctcgggacca tggcgctgcg
      181 cgcccgggcg ctctacgact ttaagtccga gaaccccggt gagatctccc tgcgggagca
      241 cgaggtgctg agcctgtgca gcgagcagga catcgagggc tggctcgaag ggatcaacag
      301 ccgcggcgac cgcggcctct tcccggcctc ctacgtgcag gtgatccgtg cgccggagcc
      361 tggccctccg gccgacggcg gcccgggagc tccggcccgc tacgccaacg tgccgcccgg
      421 cggcttcgag cctctgcccg ccgcgccacc cgccgccttc ccgccgctgc tgcagccgca
      481 ggcgtcaccc ggttccttcc agccgccggg cgccggcttt ccctacggcg ggggcgccct
      541 gcagccgtcg ccccagcagc tctacggtgg ataccaggcc agcctgggca gcgacgatga
      601 ctgggacgac gagtgggacg acagctccac ggtggccgat gagccaggcg cgctgggcag
      661 cggcgcgtac ccggacctcg acggctcgtc gtcggcgggc ggcggtgcgg ccggccgcta
      721 ccgcctgtcc acccgctcgg acctgtctct gggctcccgc ggcgtctcgg cgcccccggc
      781 gcaccaagcg tctggagcca agagctcggc cacggtgagc cgcaacctca atcgcttctc
      841 caccttcgtc aagtcgggcg gggaggcctt cgtgctggga gaggcgtcag gcttcgtgaa
      901 ggatggggac aagctgtgcg tggtgctggg tccctacggc cccgagtggc aggagaaccc
      961 ctaccccttc cagtgcacca tcgacgaccc caccaagcag accaagttca agggcatgaa
     1021 gagctacatc tcttacaagc tggtgcccac gcatacccag gtgcccgtgc acaggcgcta
     1081 taagcacttc gattggctgt atgcgcgcct ggcggagaaa ttcccagtca tctcggtgcc
     1141 ccatctgcct gagaagcagg ccaccgggcg cttcgaagag gacttcatct ccaaacgcag
     1201 gaagggtctg atctggtgga tgaaccacat ggccagccac ccggtgctgg cgcagtgcga
     1261 cgtcttccag catttcctga cctgccccag cagcactgat gagaaggcct ggaaacaggg
     1321 taagcggaag gctgagaagg atgagatggt gggcgccaac ttcttcctca ctctgagcac
     1381 cccacctgcc gccgccctgg acctgcagga ggtggagagc aagatagatg gcttcaaatg
     1441 cttcaccaag aagatggacg acagtgcgtt gcagctcaac cacaccgcca acgagtttgc
     1501 gcgcaagcag gtgactggct tcaagaagga gtatcagaag gtgggccagt ccttccgggg
     1561 tctcagccaa gcctttgagc tggatcagca ggccttctcc gtgggtctga atcaggccat
     1621 tgccttcact ggagacgcct acgacgccat cggcgaactc ttcgctgagc agcccaggca
     1681 ggacctggac ccagtcatgg acctgttagc actgtatcag gggcacctgg ccaacttccc
     1741 agacatcatc catgttcaga aaggagctct taccaaagta aaggagagta ggcgacacgt
     1801 ggaagaaggg aagatggagg tccaaaaagc tgacggcatt caagaccgct gtaacactat
     1861 ttccttcgcc acgttggccg agattcatca cttccatcaa attagagtaa gagactttaa
     1921 atcacagatg caacattttt tacaacaaca aataatattt ttccaaaaag tgacccagaa
     1981 gttggaagag gcgcttcaca aatacgacag cgtctaatga ctgcacatgg gaccgcgctc
     2041 ttgttttcag ttgaacgata atttccacag cagaacaaaa cctgccttct cagagctgtt
     2101 gccaactcta ggtggtacaa ggacggcttt gtgttcagcc gaaaccggct ggatatataa
     2161 ttatgtagga aagaagcagt taatatggct atgtagcaga aacagtacca cactttgtaa
     2221 ctaaattata ctatgtatgc ctacactacc attgtaactt ttggataatg attatactat
     2281 ttgccttatt gctttttgaa gtatgggtat attagtgtat actttgtaga cctcaaaacc
     2341 catgaagagt ctcaaagaag ctggctggat aaaagcctgc tgtggatgcc tttttagtct
     2401 cagagatcga gactacctaa atccaaccta ttctctgttt acaaactcca accggagcag
     2461 ctatgcgact ttgtgccttt agtccgcttg ttttcctttc tgtcccacct gggttcgagc
     2521 ccccaacgtt tctgatggaa agagcaaagg gcgggcatgt tggtgacaag ccgatgacaa
     2581 gctcccattt ctgggggtgg tgggagaacc agtggccatc actttgcaca ggaagcatcg
     2641 cctggtaaga tgctggcagt tacagaggca ggagacgctt ctgccgtctc tggatgtgaa
     2701 gtctcgtagg ggagaaggca gtgtgccata ttccctcaca tctgtagttc acggcctcga
     2761 ctcaagggtc gcacggattg ggcctgagga tttcggcagt gccctgagca cgtggagaag
     2821 gaggaatccg atcggggata aagaacagaa acagtgggtg acaacgcact ccatcttagt
     2881 ttgggggagg gtctcctgtc ttcctttttc ttttttcttt tttcttttat agcttgaaat
     2941 tttaatgttc agctttttgt ttcggtttca aatggatcta cactgttaac tgaatgagac
     3001 tccactgtga ttcactcgtt tacttaatca aaaaaaattt cagggatgtc tgtaaatttc
     3061 agtgttgtac gcgatgagaa gtgctgttgg ttgatttaag gagggaccag aaataatttc
     3121 tactattcca gtactgaaag aaaaaaaaaa tactgattta tactgttttt aaaaactaag
     3181 tattgataaa gcccccctca gaacatttaa ccttaaaatt attttgaata tcgcctttta
     3241 ttattagaag ggagctgcaa atgactgaca aataccaaaa agatttacat gcaggcttca
     3301 tctaaaaagc acaaagaggt tctggtgtga aatgcccaaa tctcaactgt tttttgtagt
     3361 tgctgagcta aataatgtga ttcttgagtt tacagatgta agagctgtca ctgaaggctg
     3421 aggtccctgc atctgctgtc cctgtgaact acttccacca ccccggaaac cctggtcctg
     3481 acatggtaac gtgggggtac agaggccagg ctcagagggg gtgagccaca gttatccgaa
     3541 agggtcagct tgcagaaggg tcaagcaagg aaaggcgagt gggataatta cttcacagca
     3601 cattcactct ctacaaagaa atcacatatg ggttgacatt ttaagaacgg atgatgatca
     3661 ttttgacctc tggtcaaatc cttgtgcttc agaactctga ggcggacgtg gcatcctgtg
     3721 gcgctgtctt tactacaggc acgtgggact gccgccaaaa gccatgctct cttaaaaagc
     3781 aacttcctct cttggattgc aaagtacagc gagataaaga aaacgcatat atatttaaaa
     3841 attaatttta ttccagaatt ttggaggtta caatgatagc atttaagttt gaattggtgt
     3901 tgaagaagca agctctctgc gtttcagatg atttgagcgt cccatttatt tgcctctttg
     3961 ttttgatggt ggtttgattt tttttttctt ttaataaaat tactaaactt gtgcaatagt
     4021 agcaaggaca tccatcacct gaggtgtctg attgtgcttt agccagggtg gacatagctt
     4081 aaatcataaa ctaagattaa agtccagaga agtggaaagc tgatgctgcc tcctgctgag
     4141 atagcgtttg tcctccctaa ccacacagca tcatctcacc ggctcgtggg acttgacgtg
     4201 aattctgtgg gttaatgcac caggcttact agtgtccatt ttcatccaag atccttactc
     4261 tctaacgttc ttggtcctat tgaagcattt cagtatctaa gcatactgca atgttaatac
     4321 ccaagagaaa agccattacg tacgtattct ggtcacacga tcggtgtggc accgttttat
     4381 ttgttactgt tgttgtttta ttttgttgtt tctgtttttt aaataaacta tcacaccctc
     4441 caagccaaaa aaaaaaaaaa aaaaaa
//
