LOCUS       NM_029068               2669 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus sorting nexin 16 (Snx16), transcript variant 1, mRNA.
ACCESSION   NM_029068
VERSION     NM_029068.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2669)
  AUTHORS   Hanson,B.J. and Hong,W.
  TITLE     Evidence for a role of SNX16 in regulating traffic between the
            early and later endosomal compartments
  JOURNAL   J Biol Chem 278 (36), 34617-34630 (2003)
   PUBMED   12813048
REFERENCE   2  (bases 1 to 2669)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY009391.1, AC125006.9, AK032055.1 and AI117577.1.
            
            On Nov 27, 2013 this sequence version replaced NM_029068.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032055.1, AK015872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                BY009391.1         1-21
            22-22               AC125006.9         46778-46778         c
            23-43               BY009391.1         23-43
            44-88               AK032055.1         1-45
            89-89               AC125006.9         46711-46711         c
            90-855              AK032055.1         47-812
            856-856             AC125006.9         41097-41097         c
            857-2328            AK032055.1         814-2285
            2329-2495           AC125006.9         24651-24817         c
            2496-2669           AI117577.1         1-174               c
FEATURES             Location/Qualifiers
     source          1..2669
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 2.66 cM"
     gene            1..2669
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /note="sorting nexin 16"
                     /db_xref="GeneID:74718"
                     /db_xref="MGI:MGI:1921968"
     exon            1..216
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            217..690
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             316..1350
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="sorting nexin-16 isoform a"
                     /protein_id="NP_083344.3"
                     /db_xref="CCDS:CCDS17244.1"
                     /db_xref="GeneID:74718"
                     /db_xref="MGI:MGI:1921968"
                     /translation="MATPYVPVPMPIGNSASSFTNNRNQRSSSFGSVSTSSTSSKGQL
                     EDSAVGSLKQTNVQDQMDSASSMCGSPLIRTKFTGTDSSIEYSARPREAEEQHPEAVN
                     WEDRPSTPTILGYEVMEERAKFTVYKILVKKSPEESWVVFRRYTDFSRLNDKLKEMFP
                     GFRLALPPKRWFKDNYNAEFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPG
                     PFDSLEESRAFCETLEETNYHLQRELLEKQKEVESLKKLLGEKQLHIDALETRIRTLS
                     LEPGASLYVSRAEGGQILRVEPSVLQVNRDVLDEESRADHKPHFNSREAGSVIAGIEV
                     AQLAYNAEDD"
     exon            691..777
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            778..926
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            927..996
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1133
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1253
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..2660
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2307..2312
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2331
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /note="major polyA site"
     regulatory      2629..2634
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2660
                     /gene="Snx16"
                     /gene_synonym="4930522N22Rik"
ORIGIN      
        1 ttcctggagc ggcatacctc cccctcccac tcgaggccgt cccttccctc ggttcgcggg
       61 aacctggctg ggtggctgtg cccaggcacc gagcggctgc tccggggcgg agggtcacgt
      121 gaggagtccg agtgcccggg caggacgcga cccgccgcag tccaacagga gccgccttcc
      181 ttcccctgac ggcgtggggt cgcggagcgc gccgagatag tgaattccta agaagaaagc
      241 aatgaactgc atattggttg ttctttaagt gtttggactc aaaggtgtac aagtttgttg
      301 ccaaggccaa agaagatggc aaccccgtat gtcccagttc caatgccaat aggaaactcc
      361 gcttccagct ttacaaacaa cagaaatcaa aggagttctt cttttggcag tgtttccaca
      421 agctcaacct cttccaaagg ccagttagag gactcagctg tgggcagtct taagcagacg
      481 aatgtccagg atcagatgga cagtgcatca tcaatgtgtg gtagtcctct cattaggact
      541 aaatttacag ggacagattc atccattgag tattctgcta gaccaagaga ggctgaagag
      601 cagcatcctg aggcagtgaa ctgggaagac agaccttcaa cacctacaat tctaggttac
      661 gaggttatgg aagagcgggc caaattcact gtatataaaa tcctagtaaa gaaaagccca
      721 gaagaaagct gggtagtttt ccgaagatac actgacttct ccaggcttaa tgacaaatta
      781 aaagagatgt ttccaggctt tcgattagca cttcctccaa aacgctggtt taaagataat
      841 tataatgcgg aatttctaga agatagacaa ttaggactac aagcatttct tcagaaccta
      901 gtagctcaca aggacattgc taactgcctt gcagtgagag aatttctttg tctggatgat
      961 ccaccaggtc catttgatag cctagaagaa agcagggctt tctgtgagac tttagaagag
     1021 actaactacc atttacaaag agaactgcta gagaagcaaa aagaggtgga atccctgaag
     1081 aaactgctcg gggaaaagca acttcacata gatgctttag agaccagaat cagaacattg
     1141 tccttagaac ctggagcatc actgtatgtg tcaagagcag aaggtggaca gatcctaagg
     1201 gtggagccct ctgtacttca agtcaatcgg gatgtcttgg atgaagaatc tagagctgat
     1261 cataagccac acttcaactc tagagaagcc ggaagtgtga tagcaggcat agaagtcgca
     1321 cagttggcat ataatgctga agatgactaa cacactggtg actcttcctc cacttctcat
     1381 ttcagcagag tagcaactgc catcctaata gactgaaaca caagagaaca ggaatgcacg
     1441 tgtataaagt ttacataaag tttttttaag ttattggaat aggaactata gtcactgctg
     1501 ctttcaatgt cttttatcca gcattgtatt tactacattg aaaaaaaaaa aaaaaaaccc
     1561 agttagaatt gttatcaggg cccatattct taaagacttt acataaatta ttatagtgtc
     1621 ttgcctgtat attgctccag actagtgtgt ttgtgtgtgt atatgtgtgc ttgctttgtc
     1681 ttaaatcacc acttacatag gtgaaaatga attgcatgtt agaatctgga taatgtctct
     1741 atctcagaca ggatataggt taaaccagtg aacacccagg aaagaaaaat aagaatccaa
     1801 cttgaaatgt taatatgtct catcatctct agatacaaat tgcttatttg aaatgttgat
     1861 actatttaaa agatgacttt ctagaaccaa agataatgtg ttttgaagag ttataattag
     1921 ataagcaaag tgataaaata gccttgattc aagtgatgat taattaatgt caagatactt
     1981 actgtcctgg tttattaata tattatactg ggatattttc tgcataatct tcaactcaat
     2041 tttctaccca taaattcact ggggtttgcc tcattcagaa cactacctct ttttgctaat
     2101 caaggcatat tcttttcaaa atatattaca gtttttaggg aagtgaatta cagaaaacga
     2161 aaaaaataaa taaccatgta tactgcaaag ttcccaagta gcttgactcc tggtgttcca
     2221 tatgtacttc tgtgtatgtg aggatgttat gctgtactat ggctgatttt gtttatatat
     2281 ttagccaact gatgcacttt atgataatta aactcatttg tgccaagttc agttgggtga
     2341 gtttctttag taaatagagt tagctggaag gatggtaacc gagccttcac tgttactgag
     2401 aagtctccca gggtctgtga gtcactcttg tgaagcgttt gtcctatttc agctctctgt
     2461 acagttgtga aatgccttgt ctcttcttga tactatcaac tgcatgtttt ctatttctgc
     2521 tgtttgcata ttagtcttag tgtgcattgt aatcacagta acatcttgaa gttcaagttg
     2581 gcattggact acataagctt tctaaaatct gaaagaacct ccttgagaaa taaaatacca
     2641 tctttatttc tcctttgcaa aaaaaaaaa
//
