LOCUS       NM_001408827            1171 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus sorting nexin 13 (Snx13), transcript variant 14, mRNA.
ACCESSION   NM_001408827
VERSION     NM_001408827.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1171)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1171)
  AUTHORS   Zheng,B., Tang,T., Tang,N., Kudlicka,K., Ohtsubo,K., Ma,P.,
            Marth,J.D., Farquhar,M.G. and Lehtonen,E.
  TITLE     Essential role of RGS-PX1/sorting nexin 13 in mouse development and
            regulation of endocytosis dynamics
  JOURNAL   Proc Natl Acad Sci U S A 103 (45), 16776-16781 (2006)
   PUBMED   17077144
  REMARK    GeneRIF: Snx13-null embryos are defective in nutrient uptake and
            transport, which may contribute to the other developmental
            abnormalities observed.
REFERENCE   3  (bases 1 to 1171)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140376.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK148157.1, SRR17253011.1360868.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               AC140376.3         76638-76857         c
            221-333             AC140376.3         45037-45149         c
            334-436             AC140376.3         41078-41180         c
            437-526             AC140376.3         38021-38110         c
            527-648             AC140376.3         37065-37186         c
            649-770             AC140376.3         32565-32686         c
            771-1171            AC140376.3         32080-32480         c
FEATURES             Location/Qualifiers
     source          1..1171
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 15.67 cM"
     gene            1..1171
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="sorting nexin 13"
                     /db_xref="GeneID:217463"
                     /db_xref="MGI:MGI:2661416"
     exon            1..220
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..916
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="isoform 13 is encoded by transcript variant 14"
                     /codon_start=1
                     /product="sorting nexin-13 isoform 13"
                     /protein_id="NP_001395756.1"
                     /db_xref="GeneID:217463"
                     /db_xref="MGI:MGI:2661416"
                     /translation="MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLAFYILCFVGGGL
                     VVTLLYGKTNSEKYLEQCEHSFLPPTSSGVPKCLEEMKREARTIKIDRRLTGANIIDE
                     PLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTR
                     IVDDFGTHLRVFRKAQQRVTEKDDQVKGTAEDLVETFFEVEVEMEKDVCRDLVCTSPK
                     DEEGFTFTITFLSPVTG"
     exon            221..333
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            334..436
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            437..526
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            527..648
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..770
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            771..1171
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1151..1156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="hexamer: AATAAA"
     polyA_site      1171
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="major polyA site"
ORIGIN      
        1 gcggacgtcg ctcttccaag atggcggcgc gtccgtcgcg agcagccggg ccggggggaa
       61 gccagcgaag ccgagtaaag ccgccgcccg ggacaggact gaagcagcag ttgccgccgt
      121 tggcggcggc ccgggcagtt tccgctgctg ctacggctat tgccatgcgg cgaggctagg
      181 gaggacctca ctcccccggg gtgtaatgat gttaacagag gccagtctat ccatatgggg
      241 atggggaagc cttggcattg tcctttttct aataaccttt ggaccctttg taatatttta
      301 tttggcattt tatatcctct gctttgtggg agggggttta gtggttactc ttctgtatgg
      361 gaaaactaac tcagaaaaat acctagaaca gtgtgaacac tcatttcttc ctccaacatc
      421 atctggggtt cctaagtgct tagaagaaat gaaacgcgaa gccaggacta taaagattga
      481 cagaagattg acgggtgcca atataattga tgagcctctc cagcaagtta tccagttttc
      541 cttgagggat tatgtccagt actggtatta tacattaagt gatgatgagt catttcttct
      601 tgaaattagg caaactcttc aaaatgcgct cattcagttt gctactaggt caaaagaaat
      661 agactggcag ccttatttta ctacacgcat tgtagatgat tttggcactc acctacgagt
      721 attcagaaag gcccaacaga gagtaacaga gaaagacgat caagtaaaag gtacagcaga
      781 ggatctggta gaaacctttt ttgaagttga agttgaaatg gagaaggatg tttgccggga
      841 tctagtgtgc acttctccca aagatgaaga aggtttcact tttactataa cttttttgag
      901 tccagtcaca ggatagagac aaggggacag agagcaattc taaggtggca tttttcttac
      961 acaggatagc tttatataga aaacactatt ttattgtaat cctttcaagt agcttctaca
     1021 ttcttttctc atcctgaagg ttatctttaa ataactgaac acttacattt taagaacaat
     1081 agttaatttt aatttactat ctctaccccg agtatacctg ttaccctaaa atcatttcta
     1141 attaatttca aataaaatgt ttaaattgtt a
//
