LOCUS       NM_001408823            3679 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus sorting nexin 13 (Snx13), transcript variant 10, mRNA.
ACCESSION   NM_001408823
VERSION     NM_001408823.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3679)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3679)
  AUTHORS   Zheng,B., Tang,T., Tang,N., Kudlicka,K., Ohtsubo,K., Ma,P.,
            Marth,J.D., Farquhar,M.G. and Lehtonen,E.
  TITLE     Essential role of RGS-PX1/sorting nexin 13 in mouse development and
            regulation of endocytosis dynamics
  JOURNAL   Proc Natl Acad Sci U S A 103 (45), 16776-16781 (2006)
   PUBMED   17077144
  REMARK    GeneRIF: Snx13-null embryos are defective in nutrient uptake and
            transport, which may contribute to the other developmental
            abnormalities observed.
REFERENCE   3  (bases 1 to 3679)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140376.3 and AC122314.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC067201.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               AC140376.3         76638-76857         c
            221-333             AC140376.3         45037-45149         c
            334-436             AC140376.3         41078-41180         c
            437-526             AC140376.3         38021-38110         c
            527-648             AC140376.3         37065-37186         c
            649-770             AC140376.3         32565-32686         c
            771-872             AC140376.3         32379-32480         c
            873-961             AC140376.3         31136-31224         c
            962-1045            AC140376.3         25736-25819         c
            1046-1184           AC140376.3         23372-23510         c
            1185-1273           AC140376.3         22940-23028         c
            1274-1373           AC140376.3         20909-21008         c
            1374-1567           AC140376.3         18749-18942         c
            1568-1672           AC140376.3         17232-17336         c
            1673-1805           AC140376.3         16493-16625         c
            1806-1843           AC140376.3         13388-13425         c
            1844-1913           AC140376.3         11545-11614         c
            1914-2053           AC140376.3         4144-4283           c
            2054-2161           AC140376.3         1024-1131           c
            2162-2272           AC122314.4         150193-150303       c
            2273-2434           AC122314.4         142551-142712       c
            2435-2506           AC122314.4         141353-141424       c
            2507-3679           AC122314.4         140046-141218       c
FEATURES             Location/Qualifiers
     source          1..3679
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 15.67 cM"
     gene            1..3679
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="sorting nexin 13"
                     /db_xref="GeneID:217463"
                     /db_xref="MGI:MGI:2661416"
     exon            1..220
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..2542
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="isoform 9 is encoded by transcript variant 10"
                     /codon_start=1
                     /product="sorting nexin-13 isoform 9"
                     /protein_id="NP_001395752.1"
                     /db_xref="GeneID:217463"
                     /db_xref="MGI:MGI:2661416"
                     /translation="MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLAFYILCFVGGGL
                     VVTLLYGKTNSEKYLEQCEHSFLPPTSSGVPKCLEEMKREARTIKIDRRLTGANIIDE
                     PLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTR
                     IVDDFGTHLRVFRKAQQRVTEKDDQVKGTAEDLVETFFEVEVEMEKDVCRDLVCTSPK
                     DEEGFLRDLCEVLLYLLLPPGDFQSKIMRYFVREILARGILLPLINQLSDPDYINQYV
                     IWMIRDSNCNYEAFMNIIKLSDNIGELEAVRDKAAEELQYLRSLDTAGDDINTIKNQI
                     NSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMDYMQ
                     QTGGQAHLFFWMTVEGYRVTAQQQLEVLSGRQRDGKQQTNQTKGLLRAAAVGIYEQYL
                     SEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNAL
                     YVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDLSSVTSDDSVQLHAYIS
                     DTGVCNDHGKTYALYAITVHRRNLNTEEMWKTYRRYSDFHDFHMRITEQFENLSSILK
                     LPGKKTFNNMDRDFLEKRKKDLNAYLQLLLTPEMMKASPALAHCVYDFLENKAYSKGK
                     GDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGVTKMSDNVGRMSERLGQDIKQSF
                     FKVPPLITKTDSDPEHCRVSAQLDDNTAHVPDFNILI"
     exon            221..333
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            334..436
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            437..526
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            527..648
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..770
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            771..872
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            873..961
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1045
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1184
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1273
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1373
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1567
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..1672
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1805
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1843
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1844..1913
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2053
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2054..2161
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2272
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..2434
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2506
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2507..3679
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3525..3530
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="hexamer: AATAAA"
     polyA_site      3546
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="major polyA site"
     regulatory      3652..3657
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="hexamer: AATAAA"
     polyA_site      3679
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="major polyA site"
ORIGIN      
        1 gcggacgtcg ctcttccaag atggcggcgc gtccgtcgcg agcagccggg ccggggggaa
       61 gccagcgaag ccgagtaaag ccgccgcccg ggacaggact gaagcagcag ttgccgccgt
      121 tggcggcggc ccgggcagtt tccgctgctg ctacggctat tgccatgcgg cgaggctagg
      181 gaggacctca ctcccccggg gtgtaatgat gttaacagag gccagtctat ccatatgggg
      241 atggggaagc cttggcattg tcctttttct aataaccttt ggaccctttg taatatttta
      301 tttggcattt tatatcctct gctttgtggg agggggttta gtggttactc ttctgtatgg
      361 gaaaactaac tcagaaaaat acctagaaca gtgtgaacac tcatttcttc ctccaacatc
      421 atctggggtt cctaagtgct tagaagaaat gaaacgcgaa gccaggacta taaagattga
      481 cagaagattg acgggtgcca atataattga tgagcctctc cagcaagtta tccagttttc
      541 cttgagggat tatgtccagt actggtatta tacattaagt gatgatgagt catttcttct
      601 tgaaattagg caaactcttc aaaatgcgct cattcagttt gctactaggt caaaagaaat
      661 agactggcag ccttatttta ctacacgcat tgtagatgat tttggcactc acctacgagt
      721 attcagaaag gcccaacaga gagtaacaga gaaagacgat caagtaaaag gtacagcaga
      781 ggatctggta gaaacctttt ttgaagttga agttgaaatg gagaaggatg tttgccggga
      841 tctagtgtgc acttctccca aagatgaaga aggattccta agggatttgt gtgaggtttt
      901 attatattta ttgctacctc ctggagattt ccagagcaag atcatgcgat actttgtcag
      961 ggaaatcctt gcacgaggaa ttcttcttcc attaataaat caactcagtg atcctgatta
     1021 tattaatcaa tatgtcatat ggatgatccg tgattcaaat tgcaactatg aggcctttat
     1081 gaacattatt aaattaagtg acaatattgg agagttagag gcagtcagag ataaggcagc
     1141 agaagagcta cagtatctta gatccttaga tacagccggt gatgatatca acactatcaa
     1201 aaatcaaata aatagcttat tatttgtaaa gaaagtatgt gattcaagaa tacagcggtt
     1261 acagtcaggc aaagaaataa atactgtgaa gctagcagca aactttggga aactttgtac
     1321 agtccccttg gacagcattc ttgtagacaa tgttgcacta caatttttta tggattatat
     1381 gcagcaaact ggaggccaag cacatctctt cttctggatg acagtggaag ggtaccgggt
     1441 tacagcccag caacagctcg aggttctctc aggtcgccag agagatggca aacagcagac
     1501 caaccaaacc aaaggtcttt taagagcagc agctgttgga atttatgagc agtatttatc
     1561 tgaaaaggca tctccaagag ttactgttga tgactattta gtggcaaaac tagcagatac
     1621 tttgaatcat gaagacccaa ctccagaaat ctttgatgac attcaaagaa aggtatatga
     1681 actgatgcta cgagatgaaa gattttatcc ttcctttagg cagaatgcgc tctatgtgcg
     1741 aatgctagct gagcttgaca tgttaaaaga tcctagtttc agaggatcag atgatgggga
     1801 tggagaatct tttaatgggt ctcctacagg aagcataaat ttgtctttag atgacctttc
     1861 aagtgtgact tctgatgatt ctgtacaact tcatgcctac atttcagaca ctggcgtttg
     1921 taatgatcat ggcaagacat atgcactata tgccatcact gtacaccggc gcaacctaaa
     1981 cactgaggag atgtggaaaa cctatcggcg ttatagtgac ttccatgact tccacatgag
     2041 aatcactgag cagtttgaaa atctgtcaag catattgaag cttcctggta aaaagacgtt
     2101 taacaatatg gatagagatt ttttagaaaa gaggaaaaag gatttaaatg cctacttgca
     2161 gttactcttg actcctgaaa tgatgaaggc atccccggcg ctggctcact gtgtctatga
     2221 tttccttgag aacaaagcct acagtaaagg gaagggtgat tttgctcgaa agatggacac
     2281 tttcgtaaat ccgcttcgca actctatgag gaatgtttca aatgcagtca aatcccttcc
     2341 tgatagcttg gcagaaggag tgacaaaaat gtcggacaac gtgggcagaa tgtcagagag
     2401 attagggcaa gacataaagc agtcattttt taaggtccct cctttaatta cgaagactga
     2461 ttcagatcct gaacattgtc gagtctcagc tcagcttgat gataatactg cacatgttcc
     2521 tgacttcaac attttaattt gaacaaacaa gcaaacagtt accagggccc tagaacctac
     2581 ggtcctccct gcctgcatag cctcctctgc cgtgggcccc tctgccgtgg acttactgct
     2641 ctcctgactc ttgtcctgct ttatacttga gacttttaaa tggaactata aggatagtct
     2701 cccttatgca tgttgttttt ctttgttgtt gttcaacctt gtggcagttt ttttatgctg
     2761 taatatacta gttctttctc aatacctgta tctttgcagt atttgtattt agtcttataa
     2821 atttgtattg gattatgtac agaactctga atagttttat tcatattata gaaatgagaa
     2881 gaataaatat atattcttct acttaagagt cagaatatat ataggtctat atattctgta
     2941 gtatgtgcta cgaaataatg ttccaaaact gtatcattat tactatcaca atatgagttt
     3001 taatcttcta catctggcta gagtcagtat ttatatctct gtagattcat gtatgatagc
     3061 cattcagggt catgtcttgt gggtgtctaa atcttttcct tatttttcta ttgactcagc
     3121 tgtgtgtgtt ttttagtgtt atattaactt gggtgctgaa tattatctga gcatgaggtg
     3181 tcatatgcat gatgtatatt atgtatctct gaagtaccta ccccctgctg tctgttgctt
     3241 ttgtaactct atatgttgcc ctgtgatttt ttttttttac aatttttctt gctttgccat
     3301 ggcaacattt aaatttgcac ttcatctgat taattatatg tagagattga gtaagagctc
     3361 atctccattt cctaaaggtc catctttccc tgtttgctgt ggtcttcctt accatatatg
     3421 tgtgcttctg ttcttgaatg gttttgaatc tgggctcagg gctcttaaag agatttatct
     3481 taaacataat ttcctgtttt cagtttccag atagatttgt taataataaa gtttcatata
     3541 tgtgtatatt ttccttcttt aagatcattt taggatactt catgagtaca atgtataata
     3601 tctgtaacat ctttcactct ggattttata gttaggtttt aaaaatatat taataaactg
     3661 attttatttt atcagataa
//
