LOCUS       NM_001408818            6115 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus sorting nexin 13 (Snx13), transcript variant 5, mRNA.
ACCESSION   NM_001408818
VERSION     NM_001408818.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6115)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6115)
  AUTHORS   Zheng,B., Tang,T., Tang,N., Kudlicka,K., Ohtsubo,K., Ma,P.,
            Marth,J.D., Farquhar,M.G. and Lehtonen,E.
  TITLE     Essential role of RGS-PX1/sorting nexin 13 in mouse development and
            regulation of endocytosis dynamics
  JOURNAL   Proc Natl Acad Sci U S A 103 (45), 16776-16781 (2006)
   PUBMED   17077144
  REMARK    GeneRIF: Snx13-null embryos are defective in nutrient uptake and
            transport, which may contribute to the other developmental
            abnormalities observed.
REFERENCE   3  (bases 1 to 6115)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140376.3 and AC122314.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784644.148834.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849375,
                                           SAMN00849380 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               AC140376.3         76638-76857         c
            221-333             AC140376.3         45037-45149         c
            334-436             AC140376.3         41078-41180         c
            437-526             AC140376.3         38021-38110         c
            527-648             AC140376.3         37065-37186         c
            649-770             AC140376.3         32565-32686         c
            771-872             AC140376.3         32379-32480         c
            873-961             AC140376.3         31136-31224         c
            962-1045            AC140376.3         25736-25819         c
            1046-1184           AC140376.3         23372-23510         c
            1185-1273           AC140376.3         22940-23028         c
            1274-1373           AC140376.3         20909-21008         c
            1374-1567           AC140376.3         18749-18942         c
            1568-1672           AC140376.3         17232-17336         c
            1673-1805           AC140376.3         16493-16625         c
            1806-1843           AC140376.3         13388-13425         c
            1844-1913           AC140376.3         11545-11614         c
            1914-2053           AC140376.3         4144-4283           c
            2054-2161           AC140376.3         1024-1131           c
            2162-2323           AC122314.4         142551-142712       c
            2324-2395           AC122314.4         141353-141424       c
            2396-2541           AC122314.4         136562-136707       c
            2542-2610           AC122314.4         136265-136333       c
            2611-2723           AC122314.4         134453-134565       c
            2724-6115           AC122314.4         127253-130644       c
FEATURES             Location/Qualifiers
     source          1..6115
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 15.67 cM"
     gene            1..6115
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="sorting nexin 13"
                     /db_xref="GeneID:217463"
                     /db_xref="MGI:MGI:2661416"
     exon            1..220
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..2971
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="isoform 5 is encoded by transcript variant 5"
                     /codon_start=1
                     /product="sorting nexin-13 isoform 5"
                     /protein_id="NP_001395747.1"
                     /db_xref="GeneID:217463"
                     /db_xref="MGI:MGI:2661416"
                     /translation="MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLAFYILCFVGGGL
                     VVTLLYGKTNSEKYLEQCEHSFLPPTSSGVPKCLEEMKREARTIKIDRRLTGANIIDE
                     PLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTR
                     IVDDFGTHLRVFRKAQQRVTEKDDQVKGTAEDLVETFFEVEVEMEKDVCRDLVCTSPK
                     DEEGFLRDLCEVLLYLLLPPGDFQSKIMRYFVREILARGILLPLINQLSDPDYINQYV
                     IWMIRDSNCNYEAFMNIIKLSDNIGELEAVRDKAAEELQYLRSLDTAGDDINTIKNQI
                     NSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMDYMQ
                     QTGGQAHLFFWMTVEGYRVTAQQQLEVLSGRQRDGKQQTNQTKGLLRAAAVGIYEQYL
                     SEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNAL
                     YVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDLSSVTSDDSVQLHAYIS
                     DTGVCNDHGKTYALYAITVHRRNLNTEEMWKTYRRYSDFHDFHMRITEQFENLSSILK
                     LPGKKTFNNMDRDFLEKRKKDLNAYLQMDTFVNPLRNSMRNVSNAVKSLPDSLAEGVT
                     KMSDNVGRMSERLGQDIKQSFFKVPPLITKTDSDPEHCRVSAQLDDNVDDNIPLRVML
                     LLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVK
                     RFRDAFWPNGILAETVPCRDKAIRMRTRIAGKTKLFAIMPDELKHIIGAETTRKGILR
                     VFEMFQHNQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQSTQA
                     PSLQKR"
     exon            221..333
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            334..436
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            437..526
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            527..648
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..770
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            771..872
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            873..961
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1045
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1184
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1273
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1373
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1567
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..1672
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1805
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1843
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1844..1913
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2053
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2054..2161
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2323
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2324..2395
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2396..2541
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2542..2610
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2611..2723
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..6115
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4075..4080
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="hexamer: AATAAA"
     polyA_site      4094
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="major polyA site"
     regulatory      6094..6099
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
                     /note="hexamer: AATAAA"
     polyA_site      6115
                     /gene="Snx13"
                     /gene_synonym="mKIAA0713; Rgs-px1"
ORIGIN      
        1 gcggacgtcg ctcttccaag atggcggcgc gtccgtcgcg agcagccggg ccggggggaa
       61 gccagcgaag ccgagtaaag ccgccgcccg ggacaggact gaagcagcag ttgccgccgt
      121 tggcggcggc ccgggcagtt tccgctgctg ctacggctat tgccatgcgg cgaggctagg
      181 gaggacctca ctcccccggg gtgtaatgat gttaacagag gccagtctat ccatatgggg
      241 atggggaagc cttggcattg tcctttttct aataaccttt ggaccctttg taatatttta
      301 tttggcattt tatatcctct gctttgtggg agggggttta gtggttactc ttctgtatgg
      361 gaaaactaac tcagaaaaat acctagaaca gtgtgaacac tcatttcttc ctccaacatc
      421 atctggggtt cctaagtgct tagaagaaat gaaacgcgaa gccaggacta taaagattga
      481 cagaagattg acgggtgcca atataattga tgagcctctc cagcaagtta tccagttttc
      541 cttgagggat tatgtccagt actggtatta tacattaagt gatgatgagt catttcttct
      601 tgaaattagg caaactcttc aaaatgcgct cattcagttt gctactaggt caaaagaaat
      661 agactggcag ccttatttta ctacacgcat tgtagatgat tttggcactc acctacgagt
      721 attcagaaag gcccaacaga gagtaacaga gaaagacgat caagtaaaag gtacagcaga
      781 ggatctggta gaaacctttt ttgaagttga agttgaaatg gagaaggatg tttgccggga
      841 tctagtgtgc acttctccca aagatgaaga aggattccta agggatttgt gtgaggtttt
      901 attatattta ttgctacctc ctggagattt ccagagcaag atcatgcgat actttgtcag
      961 ggaaatcctt gcacgaggaa ttcttcttcc attaataaat caactcagtg atcctgatta
     1021 tattaatcaa tatgtcatat ggatgatccg tgattcaaat tgcaactatg aggcctttat
     1081 gaacattatt aaattaagtg acaatattgg agagttagag gcagtcagag ataaggcagc
     1141 agaagagcta cagtatctta gatccttaga tacagccggt gatgatatca acactatcaa
     1201 aaatcaaata aatagcttat tatttgtaaa gaaagtatgt gattcaagaa tacagcggtt
     1261 acagtcaggc aaagaaataa atactgtgaa gctagcagca aactttggga aactttgtac
     1321 agtccccttg gacagcattc ttgtagacaa tgttgcacta caatttttta tggattatat
     1381 gcagcaaact ggaggccaag cacatctctt cttctggatg acagtggaag ggtaccgggt
     1441 tacagcccag caacagctcg aggttctctc aggtcgccag agagatggca aacagcagac
     1501 caaccaaacc aaaggtcttt taagagcagc agctgttgga atttatgagc agtatttatc
     1561 tgaaaaggca tctccaagag ttactgttga tgactattta gtggcaaaac tagcagatac
     1621 tttgaatcat gaagacccaa ctccagaaat ctttgatgac attcaaagaa aggtatatga
     1681 actgatgcta cgagatgaaa gattttatcc ttcctttagg cagaatgcgc tctatgtgcg
     1741 aatgctagct gagcttgaca tgttaaaaga tcctagtttc agaggatcag atgatgggga
     1801 tggagaatct tttaatgggt ctcctacagg aagcataaat ttgtctttag atgacctttc
     1861 aagtgtgact tctgatgatt ctgtacaact tcatgcctac atttcagaca ctggcgtttg
     1921 taatgatcat ggcaagacat atgcactata tgccatcact gtacaccggc gcaacctaaa
     1981 cactgaggag atgtggaaaa cctatcggcg ttatagtgac ttccatgact tccacatgag
     2041 aatcactgag cagtttgaaa atctgtcaag catattgaag cttcctggta aaaagacgtt
     2101 taacaatatg gatagagatt ttttagaaaa gaggaaaaag gatttaaatg cctacttgca
     2161 gatggacact ttcgtaaatc cgcttcgcaa ctctatgagg aatgtttcaa atgcagtcaa
     2221 atcccttcct gatagcttgg cagaaggagt gacaaaaatg tcggacaacg tgggcagaat
     2281 gtcagagaga ttagggcaag acataaagca gtcatttttt aaggtccctc ctttaattac
     2341 gaagactgat tcagatcctg aacattgtcg agtctcagct cagcttgatg ataatgtgga
     2401 tgacaatatt ccacttaggg taatgctgct tctaatggat gaggtgtttg acttaaaaga
     2461 gagaaaccag tggttgagaa ggaatatcaa gaatttactc cagcagctta ttagagctac
     2521 atatggtgat actattaaca gaaaaatagt tgaccatgtt gactggatga cctcaccgga
     2581 acaagtagct gactcggtga agcgtttcag agatgcattt tggcccaatg gcattttagc
     2641 agagactgtc ccatgcagag ataaagctat tcgaatgaga acaagaattg caggaaaaac
     2701 aaaattattt gcaattatgc cagatgaact gaagcacatt attggagcgg agacaacacg
     2761 gaaaggtatt cttcgcgtgt ttgaaatgtt tcagcacaac cagctaaata ggagaatggt
     2821 gtatgtcttc ttagaaggct ttttagaaac cttatttcca cagtataaat ttcgtgaact
     2881 tttcaacaaa cttcattcaa ggtcaaagca aatgcagaaa tataaacaaa aacttcaaag
     2941 tactcaagcg ccttctttac aaaaaaggtg acactccaac gtgtgaagct ggtgttcatt
     3001 ttgtctagga ctaatggtgt ggacagatct cctggggtgt aactcccgta ctgttgtgtc
     3061 tataccagtc tttccatgtc tgaaaacaga atcctagtac atcgtaagac tggttctcct
     3121 tttcaactgt aatccaccaa taccaagaga gtcctgtgtc ttacatggtt tgctgcgtta
     3181 tttgcaacat cgagaggatc ctgccccgtc tcgttcaaga atggagtcgg tctcttctgt
     3241 tccagactaa tcagcattct ctcccagtgc cagagtgcca gagtgtgtgt gtgggagctg
     3301 agggaagcac aaagcaatgg gtcacaggta acttagctaa ctagtgtggt ggctgcagag
     3361 cgcagctcag agttggagag atttgtctcc ctcaaggatc ttgtggggca tcagcatttt
     3421 gctatcatgt gggttagcag gtgagtgatc ttcagaacaa ttgtccagtt gtttccaggt
     3481 agcctgggca aagtgaggga aagaatgccc ttagtgcagg aaatcaccct tcccaaatta
     3541 ccgtcctgtg taaagcattt taatataaag ccaatcaaaa ctagcatttg attggattta
     3601 ttattcaccg atggaaatgt tggttgattc tctttggtga tgtgctgtat gggctcggcc
     3661 ttgctcttag ggccctcacc tctccacctc tcctttggca ttctgtgcag aagaagcatg
     3721 tggtagctct cttaggagtt cacatttttt aatcttttaa cagattactg attatataga
     3781 agggaaatta tttattgtaa gaactgccaa atacattgtc cttctaaaaa ttggaaatta
     3841 aagcagtact ctattgaaag ttaccatatg ataactttaa attgtatgat ctagacatgc
     3901 cttaggtaac taccaatata gcaaatcaaa ggattaatga gcttctagtc ctatgtaaac
     3961 atacaaatgc ctaattctac tatgtgtaca tatataaaaa taaataatga aaacagaact
     4021 gtactatttt taaaaatatg cttttattta tatttcgcat aatgtaaaat tctaaataaa
     4081 gctagtacac aaaacccttt ggtgtataca tttaactccc taatatttta tatcagtgaa
     4141 acaaatacct tttccagttg tgaagccttt gcatttccta gtgttctctc cattttgtcc
     4201 attaggaagt cttcatatcc catacatgca ggatttctgt acttttaaat acttccagtg
     4261 actaagggtt tggatatatc agctcttttt gttttaaaaa tatttaacac taaaacctta
     4321 aaatagtgaa actacttttc agaccactga gccagtatcc tgatatctaa agaacgtttg
     4381 ggtgcttgtt gtaaagggac agagtattga taacccagct ctttgggagc ttggagcctg
     4441 gaatgggatt tgtcttgctg tctttcagat ccttcttacc cagtgaagcc tagtaataag
     4501 agggaagcct tcctgtaagg ctctccaatg ctcaccagtg ctgtgtgcat atgtggagta
     4561 tgcacacact cagcatgcgt tgcatgtctt tcagaattac ataagtaaag cccctttcaa
     4621 aacttgcaag tgaggaaaga ttctgtttgt ctggcagaag aaatgtttcc tatactcata
     4681 tgctcctgcc ctgccggccc ttcctcggcc ccaggcttaa aattggatgc atcaggtctg
     4741 tgggaagcct cagcatggcc acaagtgcaa taatttcata cacagcctcc tgtctcagtt
     4801 atattcttac atgagtacat ttaagtgcat acagaaggat tcatgcaaga gcctagtgtg
     4861 tacatgtgaa aataaagtga gaaaactgtc aaccagggga aaaagaggtc atacaaaatg
     4921 cagattcttc ttctaacagc cctgcaagac aactgcaacc tcaccaaaac aaaacaaaga
     4981 gcaaaatcag aactgttcga ggaagtggtc tttaaaggaa cctcggctga gaagctttta
     5041 tatttcagga gcagaaatgt caaatggcca cgtgtctgtg cacgtctgtg tcttacaaca
     5101 gagtgtggtc gttggcccta ggcttggtcc agctgtgtag agtgtttaac cgatgagtag
     5161 agtacagtat tctctggtta ataaaattat tctatttagt gcacttgttg cacagatgaa
     5221 catagacaca aagaggctat atgtcttctg ctgaacactt ttaagtcagt agtggtgcct
     5281 ttaggcaaaa ccgtcaaaat taatcattct tttgggtttt ctgatatttt ttttttcagg
     5341 tagtgtaaaa ctacaaaaaa cccatcacag cttattcacc taaaatttga ttgtatgact
     5401 taaatgtcac acttagatga gcatttccta tagctcaagt gtcccatgca gttgctggaa
     5461 acagttgtgc cattgaccag tggatgcact ttgttagcct taatttaaac aacaacaaca
     5521 acaaaatttc ttgaatatat cagtttgatc actacaagtt tgctgcaggt gtttggggaa
     5581 aaaagagtta agtgcaatga aagtgtacct ttttttttag aaaaaaatta agaacataat
     5641 tttcacaatc tacagtttta attttgtgca atattttcat ttaatgcatg tttgagtaat
     5701 tgtataataa ctacattttt aatgttttga gatctaattt aactgtctta ttaacccaac
     5761 aacttcattc cgttgttgct gcaccttaat taaggacttg ttttaaaagt ctttttgtca
     5821 ctccttgtaa aattcttttc ttagtagaaa attttgctta tgggagcatg gctcctgtat
     5881 tataagggaa aactaaagag cacattttag ggttttaatt gttaaaaact accttgtgca
     5941 tatctctgta tataagcgtc gatcgtgcct accgctctat caatgctctc ctctaaccaa
     6001 ggggaaagaa tcagaatgtc agttactttt attaacgaca gaaattaaaa tttttatttg
     6061 gtttgtgtta tgttctgtct gttagaaaat actaataaag tattaacaaa cagtt
//
