LOCUS       NM_025507               2257 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus SNW domain containing 1 (Snw1), mRNA.
ACCESSION   NM_025507
VERSION     NM_025507.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2257)
  AUTHORS   Liao,Z.M., Li,A.N., Cai,Y., Chen,J.J., Xu,Y., Sui,L.H., Wang,J.L.,
            Jin,P., Wang,K.S. and Yang,Z.C.
  TITLE     Skip participates in formation and lipid metabolism of beige
            adipose and might mediate the effects of SIRT1 activator BTM-0512
            on beige remodeling
  JOURNAL   Biochem Biophys Res Commun 537, 109-117 (2021)
   PUBMED   33388413
  REMARK    GeneRIF: Skip participates in formation and lipid metabolism of
            beige adipose and might mediate the effects of SIRT1 activator
            BTM-0512 on beige remodeling.
REFERENCE   2  (bases 1 to 2257)
  AUTHORS   Zhang,D., Qiao,X., Wang,L., Zhang,L., Yao,J., Wu,X., Yu,T.,
            Bostrom,K.I. and Yao,Y.
  TITLE     Skip is essential for Notch signaling to induce Sox2 in cerebral
            arteriovenous malformations
  JOURNAL   Cell Signal 68, 109537 (2020)
   PUBMED   31927035
  REMARK    GeneRIF: Skip is essential for Notch signaling to induce Sox2 in
            cerebral arteriovenous malformations.
REFERENCE   3  (bases 1 to 2257)
  AUTHORS   Rajan,S., Chu Pham Dang,H., Djambazian,H., Zuzan,H., Fedyshyn,Y.,
            Ketela,T., Moffat,J., Hudson,T.J. and Sladek,R.
  TITLE     Analysis of early C2C12 myogenesis identifies stably and
            differentially expressed transcriptional regulators whose
            knock-down inhibits myoblast differentiation
  JOURNAL   Physiol Genomics 44 (2), 183-197 (2012)
   PUBMED   22147266
REFERENCE   4  (bases 1 to 2257)
  AUTHORS   Kang,M.R., Lee,S.W., Um,E., Kang,H.T., Hwang,E.S., Kim,E.J. and
            Um,S.J.
  TITLE     Reciprocal roles of SIRT1 and SKIP in the regulation of RAR
            activity: implication in the retinoic acid-induced neuronal
            differentiation of P19 cells
  JOURNAL   Nucleic Acids Res 38 (3), 822-831 (2010)
   PUBMED   19934264
REFERENCE   5  (bases 1 to 2257)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 2257)
  AUTHORS   Pestov,N.B., Ahmad,N., Korneenko,T.V., Zhao,H., Radkov,R.,
            Schaer,D., Roy,S., Bibert,S., Geering,K. and Modyanov,N.N.
  TITLE     Evolution of Na,K-ATPase beta m-subunit into a coregulator of
            transcription in placental mammals
  JOURNAL   Proc Natl Acad Sci U S A 104 (27), 11215-11220 (2007)
   PUBMED   17592128
REFERENCE   7  (bases 1 to 2257)
  AUTHORS   Tang,J., Chang,H.Y. and Yang,X.
  TITLE     The death domain-associated protein modulates activity of the
            transcription co-factor Skip/NcoA62
  JOURNAL   FEBS Lett 579 (13), 2883-2890 (2005)
   PUBMED   15878163
REFERENCE   8  (bases 1 to 2257)
  AUTHORS   Shu,H., Chen,S., Bi,Q., Mumby,M. and Brekken,D.L.
  TITLE     Identification of phosphoproteins and their phosphorylation sites
            in the WEHI-231 B lymphoma cell line
  JOURNAL   Mol Cell Proteomics 3 (3), 279-286 (2004)
   PUBMED   14729942
REFERENCE   9  (bases 1 to 2257)
  AUTHORS   Barry,J.B., Leong,G.M., Church,W.B., Issa,L.L., Eisman,J.A. and
            Gardiner,E.M.
  TITLE     Interactions of SKIP/NCoA-62, TFIIB, and retinoid X receptor with
            vitamin D receptor helix H10 residues
  JOURNAL   J Biol Chem 278 (10), 8224-8228 (2003)
   PUBMED   12529369
  REMARK    GeneRIF: interaction with vitamin D receptor helix H10 residues
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK166163.1, AK009218.1 and AK012384.1.
            
            On May 1, 2007 this sequence version replaced NM_025507.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164138,
                              SAMN01164140 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-645               AK166163.1         2-646
            646-1427            AK009218.1         1-782
            1428-1869           AK012384.1         783-1224
            1870-2257           AK009218.1         1225-1612
FEATURES             Location/Qualifiers
     source          1..2257
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 41.67 cM"
     gene            1..2257
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /note="SNW domain containing 1"
                     /db_xref="GeneID:66354"
                     /db_xref="MGI:MGI:1913604"
     exon            1..52
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1649
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /note="SKI interacting protein; nuclear protein SkiP;
                     ski-interacting protein"
                     /codon_start=1
                     /product="SNW domain-containing protein 1"
                     /protein_id="NP_079783.2"
                     /db_xref="CCDS:CCDS49121.1"
                     /db_xref="GeneID:66354"
                     /db_xref="MGI:MGI:1913604"
                     /translation="MALTSFLPAPTQLSQDQLEAEERARSQRSLQTSLVSSRREPPPY
                     GYRKGWIPRLLEDFGDGGAFPEIHVAQYPLDMGRKKKMSNALAIQVDPEGKIKYDAIA
                     RQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVA
                     AAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKI
                     PRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQ
                     TVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARER
                     RAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVI
                     ALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRP
                     SKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRKQRGREGPVQFEEDPFGLDKFLEEA
                     KQHGGSKRPSDSSRPKEHEHEGKKRRKE"
     exon            53..206
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            207..368
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            369..464
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            465..571
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            572..676
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            677..746
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            747..812
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            813..929
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1071
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1168
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1286
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1450
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..2257
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2233..2238
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /note="hexamer: AATAAA"
     polyA_site      2246
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /note="major polyA site"
     polyA_site      2252
                     /gene="Snw1"
                     /gene_synonym="2310008B08Rik; NCoA-62; Skiip; SKIP"
                     /note="major polyA site"
ORIGIN      
        1 ggcgacgttg tggcctgcgc aggaagaagc ggaagaagat ggcgctcacc agctttttac
       61 ctgcgcctac tcagctgtct caggaccaac ttgaagctga agaaagggca agatctcaga
      121 gatcactgca gacctctctg gtctcctctc gaagggagcc tcccccatac ggatatagga
      181 aaggctggat tccaagacta ttagaggatt ttggagatgg aggtgctttc ccagaaatcc
      241 atgtggccca gtatcctctg gatatggggc gaaagaaaaa aatgtcgaat gctctggcca
      301 ttcaggtgga tcctgaaggg aaaattaagt atgatgcaat tgctcggcag ggacagtcca
      361 aagacaaggt catttacagc aaatacactg acctggttcc taaggaggtt atgaatgcag
      421 atgacccaga cctgcaacgg cccgatgaag aggcaattaa agagataaca gaaaagacta
      481 gagttgcctt ggagaaatct gtgtcgcaga aggttgctgc agccatgcca gttcgtgcag
      541 ctgacaagct ggctcctgct cagtatatcc gctacacacc atctcagcaa ggagtagcat
      601 tcaattctgg agctaaacag agggtcattc ggatggtaga aatgcagaaa gacccaatgg
      661 agcctccaag attcaagatt aataagaaaa ttccccgggg accaccgtct cctcctgcac
      721 ctgtaatgca ctctcctagt cggaagatga ctgtaaagga acaacaagag tggaagatcc
      781 cgccttgtat ttccaactgg aagaacgcta aggggtatac gatcccatta gataaacggc
      841 tggctgctga tggaagagga cttcagactg tccacataaa tgaaaatttt gccaaactgg
      901 ctgaagcgct ctacattgct gatcggaagg ctcgtgaagc ggtggaaatg cgagcccagg
      961 tagagagaaa gatggctcaa aaagaaaagg agaaacatga agagaaactt agagaaatgg
     1021 cccagaaagc cagagaaagg agagctggaa tcaaaaccca cgtggagaaa gaggatggag
     1081 aggcccgtga gagagatgaa atccgtcatg acaggcgaaa agagagacag catgaccgga
     1141 acctttccag ggcagctcct gataagaggt caaaactaca gagaaatgaa aatcgagaca
     1201 tcagtgaagt cattgctctt ggtgtgccca atcctcgaac ttccaatgaa gttcagtatg
     1261 accaaaggct cttcaaccaa tccaagggta tggacagtgg atttgcaggt ggagaagatg
     1321 aaatttacaa tgtttatgat caagcctgga gaggtgggaa agatatggcc cagagcatct
     1381 acaggcccag taaaaatctg gacaaggaca tgtatggtga tgacctggaa gccaggataa
     1441 agaccaacag atttgttcct gataaggagt tttctggatc agaccgcaaa cagagaggcc
     1501 gagaaggacc agtgcagttt gaggaggatc cttttggttt ggacaagttt ttggaagaag
     1561 ccaaacagca cggtggttct aaaagaccct ctgatagcag tcgccccaag gaacatgagc
     1621 atgaaggcaa gaagcggagg aaagagtaga gggacctctt aaaactaaat ctgacatatg
     1681 cagcagagga ctgcctggtc tggcctcatt gtgaacagat gtccccaccc cctccagaca
     1741 cttgagactc cagggaatag ggcgtcctag tgggtggggg tggggacatc ctcttggaaa
     1801 tgggggagga ggaatgggat gaggaatcat cagagagatg accaggaggg agataaagac
     1861 tggactgtta aaaaaaaaaa aaagattaaa aaatctcgat gatagatccc agcactcctt
     1921 ttcattctgg gatgtagggg cattgattat tctatttcgg agtagttttt ttatatggaa
     1981 tggggttatg tttgtgcttc tccaatcttg cagcacttag aaataccact gccccacaca
     2041 gaattgagat tccttccttg tgtgtgacac taatccagct gtaacctttt ctgtaaacgt
     2101 tatgaataac ctcacctcaa atggtgagtg ggctaatgtt cacacactgg agctctgtca
     2161 actgcatttg ccctgtgtgc ttctccaccg cgccatgggg aactaaggtc ttgcttagtg
     2221 cacctcattt caaataaaaa cgtgtagaaa aagtctc
//
