LOCUS       NM_009227                508 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus small nuclear ribonucleoprotein E (Snrpe), mRNA.
ACCESSION   NM_009227
VERSION     NM_009227.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Weiss,J., Hurley,L.A., Harris,R.M., Finlayson,C., Tong,M.,
            Fisher,L.A., Moran,J.L., Beier,D.R., Mason,C. and Jameson,J.L.
  TITLE     ENU mutagenesis in mice identifies candidate genes for hypogonadism
  JOURNAL   Mamm Genome 23 (5-6), 346-355 (2012)
   PUBMED   22258617
REFERENCE   2  (bases 1 to 508)
  AUTHORS   Zanucco,E., Gotz,R., Potapenko,T., Carraretto,I., Ceteci,S.,
            Ceteci,F., Seeger,W., Savai,R. and Rapp,U.R.
  TITLE     Expression of B-RAF V600E in type II pneumocytes causes
            abnormalities in alveolar formation, airspace enlargement and tumor
            formation in mice
  JOURNAL   PLoS One 6 (12), e29093 (2011)
   PUBMED   22194995
REFERENCE   3  (bases 1 to 508)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 508)
  AUTHORS   Seraphin,B.
  TITLE     Sm and Sm-like proteins belong to a large family: identification of
            proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs
  JOURNAL   EMBO J 14 (9), 2089-2098 (1995)
   PUBMED   7744014
REFERENCE   5  (bases 1 to 508)
  AUTHORS   Fautsch,M.P., Thompson,M.A., Holicky,E.L., Schultz,P.J.,
            Hallett,J.B. and Wieben,E.D.
  TITLE     Conservation of coding and transcriptional control sequences within
            the snRNP E protein gene
  JOURNAL   Genomics 14 (4), 883-890 (1992)
   PUBMED   1478669
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY168551.1 and AW492281.1.
            
            On Oct 1, 2007 this sequence version replaced NM_009227.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB524101.1, BQ178246.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-360               BY168551.1         1-360
            361-508             AW492281.1         1-148               c
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 57.94 cM"
     gene            1..508
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /note="small nuclear ribonucleoprotein E"
                     /db_xref="GeneID:20643"
                     /db_xref="MGI:MGI:98346"
     exon            1..117
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..342
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /note="sm protein E"
                     /codon_start=1
                     /product="small nuclear ribonucleoprotein E"
                     /protein_id="NP_033253.1"
                     /db_xref="CCDS:CCDS48364.1"
                     /db_xref="GeneID:20643"
                     /db_xref="MGI:MGI:98346"
                     /translation="MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIE
                     GCIIGFDEYMNLVLDDAEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN"
     exon            118..144
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /inference="alignment:Splign:2.1.0"
     exon            145..207
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /inference="alignment:Splign:2.1.0"
     exon            208..286
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /inference="alignment:Splign:2.1.0"
     exon            287..492
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /inference="alignment:Splign:2.1.0"
     regulatory      458..463
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /note="hexamer: AATAAA"
     polyA_site      492
                     /gene="Snrpe"
                     /gene_synonym="sm-E; SME; snRNP-E"
                     /note="major polyA site"
ORIGIN      
        1 ttgcttccgg aagtcgcttt ccgaggcggc cttcctactc gtgtggtctt tgtgacttcc
       61 accatggcgt accgcggcca gggccaaaag gtgcagaagg tgatggtgca gcccatcaac
      121 cttatcttca gatacttgca aaatagatct cgaattcagg tgtggctgta tgaacaagtg
      181 aatatgcgga tagaaggttg tattattggc tttgatgagt acatgaacct cgtattagat
      241 gatgcagaag agattcattc taaaacaaag tcaagaaaac aactgggtcg gatcatgcta
      301 aaaggagata atattactct gctccaaagt gtttccaact agcagtgaat ggtgaagtct
      361 gtaggatgtt gagaagaccc cttgagcgtg tttaaagatg tctgctgcaa cctgcattta
      421 ctcaacttgt tttacttgca cattattatt aggtgacaat aaatgctgta ggaagttttt
      481 gttaaaattt taaaaaaaaa aaaaaaaa
//
