LOCUS       NM_021335               1230 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus U2 small nuclear ribonucleoprotein B (Snrpb2), mRNA.
ACCESSION   NM_021335
VERSION     NM_021335.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1230)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1230)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   3  (bases 1 to 1230)
  AUTHORS   Matsuoka,T., Sato,M., Tokoro,M., Shin,S.W., Uenoyama,A., Ito,K.,
            Hitomi,S., Amano,T., Anzai,M., Kato,H., Mitani,T., Saeki,K.,
            Hosoi,Y., Iritani,A. and Matsumoto,K.
  TITLE     Identification of ZAG1, a novel protein expressed in mouse
            preimplantation, and its putative roles in zygotic genome
            activation
  JOURNAL   J Reprod Dev 54 (3), 192-197 (2008)
   PUBMED   18360097
REFERENCE   4  (bases 1 to 1230)
  AUTHORS   Chiu,S., Kim,K., Haus,K.A., Espinal,G.M., Millon,L.V. and
            Warden,C.H.
  TITLE     Identification of positional candidate genes for body weight and
            adiposity in subcongenic mice
  JOURNAL   Physiol Genomics 31 (1), 75-85 (2007)
   PUBMED   17536020
REFERENCE   5  (bases 1 to 1230)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1230)
  AUTHORS   Isono,K., Mizutani-Koseki,Y., Komori,T., Schmidt-Zachmann,M.S. and
            Koseki,H.
  TITLE     Mammalian polycomb-mediated repression of Hox genes requires the
            essential spliceosomal protein Sf3b1
  JOURNAL   Genes Dev 19 (5), 536-541 (2005)
   PUBMED   15741318
REFERENCE   7  (bases 1 to 1230)
  AUTHORS   Tucker,K.E., Berciano,M.T., Jacobs,E.Y., LePage,D.F.,
            Shpargel,K.B., Rossire,J.J., Chan,E.K., Lafarga,M., Conlon,R.A. and
            Matera,A.G.
  TITLE     Residual Cajal bodies in coilin knockout mice fail to recruit Sm
            snRNPs and SMN, the spinal muscular atrophy gene product
  JOURNAL   J Cell Biol 154 (2), 293-307 (2001)
   PUBMED   11470819
REFERENCE   8  (bases 1 to 1230)
  AUTHORS   Laitinen,J., Saris,P., Holtta,E. and Pettersson,I.
  TITLE     U2-snRNP B' protein gene is an early growth-inducible gene
  JOURNAL   J Cell Biochem 58 (4), 490-498 (1995)
   PUBMED   7593271
REFERENCE   9  (bases 1 to 1230)
  AUTHORS   Ferreira,J. and Carmo-Fonseca,M.
  TITLE     The biogenesis of the coiled body during early mouse development
  JOURNAL   Development 121 (2), 601-612 (1995)
   PUBMED   7768196
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK013871.1.
            
            On Apr 6, 2007 this sequence version replaced NM_021335.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013871.1, SRR1660821.6408.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1230              AK013871.1         2-1231
FEATURES             Location/Qualifiers
     source          1..1230
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 70.89 cM"
     gene            1..1230
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /note="U2 small nuclear ribonucleoprotein B"
                     /db_xref="GeneID:20639"
                     /db_xref="MGI:MGI:104805"
     exon            1..30
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            31..119
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..733
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /note="U2 snRNP B''"
                     /codon_start=1
                     /product="U2 small nuclear ribonucleoprotein B''"
                     /protein_id="NP_067310.1"
                     /db_xref="CCDS:CCDS16808.1"
                     /db_xref="GeneID:20639"
                     /db_xref="MGI:MGI:104805"
                     /translation="MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALK
                     TMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKE
                     KKKEKKKAKTMEQAAAAANKKPGQGTPNAANTQGTAAPNPQVPDYPPNYILFLNNLPE
                     ETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAM
                     KITYAKK"
     exon            120..292
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            293..433
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            434..484
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            485..573
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            574..1230
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      901..906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      918
                     /gene="Snrpb2"
                     /gene_synonym="2810052G09Rik"
                     /note="major polyA site"
ORIGIN      
        1 ttagtttcaa gcggaccgcg ccggcttcag gctattggaa gggttctacc caaacatgga
       61 tatcagacca aatcacacga tttatatcaa caacatgaat gacaaaatta aaaaagaaga
      121 attgaagaga tccctgtatg cccttttttc tcagtttgga cacgtggtag atattgtggc
      181 tttaaagacc atgaagatga ggggacaggc ttttgttata tttaaggaac tgggttcatc
      241 cacaaatgct ttgagacagt tacaaggatt tccattttat ggtaaaccaa tgagaattca
      301 gtacgcaaaa acagattctg atataatatc taaaatgcgt ggtactttcg ctgacaagga
      361 aaagaaaaag gaaaagaaga aagctaaaac catggaacag gctgcagctg ctgcaaacaa
      421 gaagcctggt cagggaacac caaatgcagc taatacccaa ggcactgcag cgccaaatcc
      481 tcaggtccct gattatcctc caaattatat cctatttctt aataacttac cagaggagac
      541 aaatgagatg atgttatcca tgctgttcaa ccagttccct ggattcaagg aagttcgctt
      601 ggtaccgggg agacatgaca ttgcatttgt agaatttgag aatgatggtc aggctggagc
      661 tgccagagat gctctgcagg ggtttaagat tacaccgtcc catgccatga agatcaccta
      721 tgccaagaag taacatgtga tgccaatgtg gaaggacttg gttatttata gtgtttgttt
      781 tgatcatatt cggtcaagtc attttaaatg gttggaagtg aaggtgaagt tttgggagaa
      841 gagttgtcta atttttttta gttttgctga actatgaaat acggagcctt aattttgtac
      901 aataaacttt tatttgtatt ctgtttactg gtttattgtc ctatcatcac ttatttttgt
      961 ataaacctga aagtgtatga aactcagtaa tggggtttag gttattttgg agcagctaat
     1021 gatacagaag ttgaagggag cagattgcag caaccagtga gcagcatgtt aatagtaaaa
     1081 tgatcgccct gctgtgagta acaagacatt tgcttctgtc caaagtgcag tgctttgctg
     1141 gatggagtag ggattgcaca gtattagtgg ccatgtgata gcagctgctt attgttgtct
     1201 agaaaaacag gaaataaaat tgctgcctgc
//
