LOCUS       NM_029532               1133 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus small nuclear ribonucleoprotein 35 (U11/U12)
            (Snrnp35), mRNA.
ACCESSION   NM_029532
VERSION     NM_029532.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Doktor,T.K., Hua,Y., Andersen,H.S., Broner,S., Liu,Y.H.,
            Wieckowska,A., Dembic,M., Bruun,G.H., Krainer,A.R. and
            Andresen,B.S.
  TITLE     RNA-sequencing of a mouse-model of spinal muscular atrophy reveals
            tissue-wide changes in splicing of U12-dependent introns
  JOURNAL   Nucleic Acids Res 45 (1), 395-416 (2017)
   PUBMED   27557711
  REMARK    GeneRIF: Elevated U12-intron retention has been demonstrated in all
            examined tissues from spinal muscular atrophy mice.
REFERENCE   2  (bases 1 to 1133)
  AUTHORS   Jerome-Majewska,L.A., Achkar,T., Luo,L., Lupu,F. and Lacy,E.
  TITLE     The trafficking protein Tmed2/p24beta(1) is required for
            morphogenesis of the mouse embryo and placenta
  JOURNAL   Dev Biol 341 (1), 154-166 (2010)
   PUBMED   20178780
REFERENCE   3  (bases 1 to 1133)
  AUTHORS   Pessa,H.K., Will,C.L., Meng,X., Schneider,C., Watkins,N.J.,
            Perala,N., Nymark,M., Turunen,J.J., Luhrmann,R. and Frilander,M.J.
  TITLE     Minor spliceosome components are predominantly localized in the
            nucleus
  JOURNAL   Proc Natl Acad Sci U S A 105 (25), 8655-8660 (2008)
   PUBMED   18559850
REFERENCE   4  (bases 1 to 1133)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC043031.1.
            
            On Jun 19, 2003 this sequence version replaced NM_029532.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC043031.1, AK018232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 63.61 cM"
     gene            1..1133
                     /gene="Snrnp35"
                     /gene_synonym="6330548G22Rik"
                     /note="small nuclear ribonucleoprotein 35 (U11/U12)"
                     /db_xref="GeneID:76167"
                     /db_xref="MGI:MGI:1923417"
     exon            1..92
                     /gene="Snrnp35"
                     /gene_synonym="6330548G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            93..1092
                     /gene="Snrnp35"
                     /gene_synonym="6330548G22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..830
                     /gene="Snrnp35"
                     /gene_synonym="6330548G22Rik"
                     /note="U11/U12 snRNP 35 kDa protein; U1 snRNP-binding
                     protein homolog"
                     /codon_start=1
                     /product="U11/U12 small nuclear ribonucleoprotein 35 kDa
                     protein"
                     /protein_id="NP_083808.1"
                     /db_xref="CCDS:CCDS19677.1"
                     /db_xref="GeneID:76167"
                     /db_xref="MGI:MGI:1923417"
                     /translation="MSDWMPIAKEYDPLKAGSIDGTDEDPHDRAVWRAMLARYVPNKG
                     VTGDPLLTLFVARLNLQTKEEKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEE
                     RALMKAYRDADGLVIDQHEIFVDYELERTLRGWIPRRLGGGLGGKKESGQLRFGGRDR
                     PFRKPINLPVVKNEPHREGKRERRERSRSRDRHWDPRPRERDHDRGREKHWQERARVW
                     PENDWEREREFREERVKSRDKRDRSK"
ORIGIN      
        1 tggaggtcgg cgtgtggaat ctgcagtttc tggtaaacgg gcggtggaaa cggtttttct
       61 cgcggtgcgg aaagaacccc aaatttgtcg agagcatgag cgactggatg cccattgcca
      121 aggaatatga cccgcttaaa gctggcagca tcgatggtac agatgaagac ccacatgacc
      181 gagctgtgtg gagggccatg ctggcccgct atgtccccaa caaaggagtc accggagacc
      241 ccctccttac cctgtttgtg gcacgactga acttgcagac caaagaggaa aagttaaagg
      301 aagtcttctc ccggtatggt gacattcggc ggctgaggct ggttcgggac ctggtgacag
      361 gcttctccaa gggctacgcc ttcattgagt acaaggagga gagggccctg atgaaggcct
      421 acagagatgc tgatggcctg gtcattgacc agcacgagat attcgtggac tatgagctag
      481 agaggactct ccgtggctgg atccctcggc ggctgggtgg cggattgggt gggaaaaagg
      541 aatctgggca gctgaggttc ggtgggcgag atcggccttt ccgaaaaccc attaacttgc
      601 cagttgtcaa gaatgagcca catagagaag ggaaaaggga aaggagggag cgatctcgat
      661 ctagggacag acactgggac cccaggccca gggaacggga tcatgacagg ggccgagaga
      721 agcactggca agagagggcc agggtgtggc ctgagaatga ttgggaaaga gagagggagt
      781 tcagggagga gagggtcaaa agccgggaca agagggacag aagtaagtag aggcagcagc
      841 aggcagcctc cgtcaggctg gggcagtgcc tttagcagta ctggggattg aactagagag
      901 tgcggcatgt caggcaagcg ctccaaccac agccacatag gatgagaggg agaaacaagt
      961 gtgtaagaag aaatgtccag ctcctgtgga aatagaagag ttttcacatg ctgtcaaccc
     1021 agcacttggg agttggaggc agaaggatgg aaagagagag gggataataa agaatctgtc
     1081 ttccctttct caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
