LOCUS       NM_025665                836 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus small nuclear ribonucleoprotein 27 (U4/U6.U5)
            (Snrnp27), mRNA.
ACCESSION   NM_025665
VERSION     NM_025665.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 836)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 836)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK011937.1.
            
            On Apr 5, 2007 this sequence version replaced NM_025665.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011937.1, SRR1660813.476926.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-836               AK011937.1         2-837
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 37.75 cM"
     gene            1..836
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /note="small nuclear ribonucleoprotein 27 (U4/U6.U5)"
                     /db_xref="GeneID:66618"
                     /db_xref="MGI:MGI:1913868"
     exon            1..45
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..479
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /note="putative nucleic acid binding protein RY-1;
                     U4/U6.U5-27K; U4/U6.U5 snRNP 27 kDa protein; U4/U6.U5
                     tri-snRNP-associated protein 3"
                     /codon_start=1
                     /product="U4/U6.U5 small nuclear ribonucleoprotein 27 kDa
                     protein"
                     /protein_id="NP_079941.1"
                     /db_xref="CCDS:CCDS20315.1"
                     /db_xref="GeneID:66618"
                     /db_xref="MGI:MGI:1913868"
                     /translation="MGRSRSRSPRRERRRSRSTSRDRERRRRERSRSRERDRRRSRSR
                     SPHRRRSRSPRRHRSTSPSPSRLKERRDEEKKETKEIKNKERQITEEDLEGKTEEEIE
                     MMKLMGFASFDSTKGKKVDGSVNAYAINVSQKRKYRQYMNRKGGFNRPLDFIA"
     exon            46..166
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /inference="alignment:Splign:2.1.0"
     exon            167..279
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /inference="alignment:Splign:2.1.0"
     exon            280..359
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /inference="alignment:Splign:2.1.0"
     exon            360..424
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /inference="alignment:Splign:2.1.0"
     exon            425..836
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      764..769
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /note="hexamer: AATAAA"
     polyA_site      790
                     /gene="Snrnp27"
                     /gene_synonym="2610209M04Rik; Ry1"
                     /note="major polyA site"
ORIGIN      
        1 ggaggactcc gatgggtcga agtcgtagcc gctccccgcg tagggaacgt aggcggtccc
       61 ggtccacatc tcgggatcga gaaagaagac gccgagaaag gtccaggtcc agggagagag
      121 atcgcagaag gagccgctca agatctccac accgaagacg ctccaggtct ccaagacgac
      181 atagatccac atctccctcc ccttctcgac tgaaagaaag aagagatgag gaaaagaaag
      241 aaactaaaga aataaagaac aaagaacggc agatcactga ggaagacctg gagggtaaaa
      301 cagaggaaga aatagaaatg atgaaattaa tgggatttgc ctcttttgac tccacaaaag
      361 ggaagaaggt agacggctct gtaaatgcct atgccatcaa cgtgtctcaa aagaggaagt
      421 acaggcagta catgaatcga aaaggcggat tcaacagacc tctggatttt attgcatgaa
      481 acttgaggtg ttggatggag gatttccccc accctcgtct gggtcagaga gtattttata
      541 ttttatattt aatacacatc aaaacaggat cttgattctt ccttcttata aagtaagaaa
      601 gtcttattta tgacacccag tttacttact tttcaaggca atgtccctgg gatggccacc
      661 agcccttttg tctgtccttg ttcctttgaa actgtgtgtg ctgtcttctt ggatgcttgc
      721 taggtgttct taaaaactga aagtgaattg catacatttc cccaataaaa caatgtttct
      781 acccatttta tatttatttg acaaatatct ttattactag attaaagagt ctccct
//
