LOCUS       NM_019776               3482 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus staphylococcal nuclease and tudor domain containing 1
            (Snd1), mRNA.
ACCESSION   NM_019776
VERSION     NM_019776.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3482)
  AUTHORS   Su,C., Ma,J., Yao,X., Hao,W., Gan,S., Gao,Y., He,J., Ren,Y.,
            Gao,X., Zhu,Y., Yang,J. and Wei,M.
  TITLE     Tudor-SN promotes cardiomyocyte proliferation and neonatal heart
            regeneration through regulating the phosphorylation of YAP
  JOURNAL   Cell Commun Signal 22 (1), 345 (2024)
   PUBMED   38943195
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3482)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3482)
  AUTHORS   Su,C., Liu,M., Yao,X., Hao,W., Ma,J., Ren,Y., Gao,X., Xin,L.,
            Ge,L., Yu,Y., Wei,M. and Yang,J.
  TITLE     Vascular injury activates the ELK1/SND1/SRF pathway to promote
            vascular smooth muscle cell proliferative phenotype and neointimal
            hyperplasia
  JOURNAL   Cell Mol Life Sci 81 (1), 59 (2024)
   PUBMED   38279051
  REMARK    GeneRIF: Vascular injury activates the ELK1/SND1/SRF pathway to
            promote vascular smooth muscle cell proliferative phenotype and
            neointimal hyperplasia.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3482)
  AUTHORS   Wright,T., Wang,Y., Stratton,S.A., Sebastian,M., Liu,B.,
            Johnson,D.G. and Bedford,M.T.
  TITLE     Loss of the methylarginine reader function of SND1 confers
            resistance to hepatocellular carcinoma
  JOURNAL   Biochem J 480 (22), 1805-1816 (2023)
   PUBMED   37905668
  REMARK    GeneRIF: Loss of the methylarginine reader function of SND1 confers
            resistance to hepatocellular carcinoma.
REFERENCE   5  (bases 1 to 3482)
  AUTHORS   Liao,S.Y., Rudoy,D., Frank,S.B., Phan,L.T., Klezovitch,O., Kwan,J.,
            Coleman,I., Haffner,M.C., Li,D., Nelson,P.S., Emili,A. and
            Vasioukhin,V.
  TITLE     SND1 binds to ERG and promotes tumor growth in genetic mouse models
            of prostate cancer
  JOURNAL   Nat Commun 14 (1), 7435 (2023)
   PUBMED   37973913
  REMARK    GeneRIF: SND1 binds to ERG and promotes tumor growth in genetic
            mouse models of prostate cancer.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3482)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 3482)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 3482)
  AUTHORS   Paukku,K., Yang,J. and Silvennoinen,O.
  TITLE     Tudor and nuclease-like domains containing protein p100 function as
            coactivators for signal transducer and activator of transcription 5
  JOURNAL   Mol Endocrinol 17 (9), 1805-1814 (2003)
   PUBMED   12819296
REFERENCE   9  (bases 1 to 3482)
  AUTHORS   Derudder,E., Dejardin,E., Pritchard,L.L., Green,D.R., Korner,M. and
            Baud,V.
  TITLE     RelB/p50 dimers are differentially regulated by tumor necrosis
            factor-alpha and lymphotoxin-beta receptor activation: critical
            roles for p100
  JOURNAL   J Biol Chem 278 (26), 23278-23284 (2003)
   PUBMED   12709443
  REMARK    GeneRIF: p100 regulates the binding activity of RelB/p50 dimers via
            at least two distinct mechanisms depending on the signaling pathway
            involved.
REFERENCE   10 (bases 1 to 3482)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB613775.1, AK034914.1, BM944959.1, AB021491.1 and AC072048.4.
            
            On Oct 9, 2005 this sequence version replaced NM_019776.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133837.1, SRR1660819.132830.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                BB613775.1         1-54
            55-566              AK034914.1         3-514
            567-989             BM944959.1         245-667
            990-2940            AB021491.1         947-2897
            2941-3482           AC072048.4         16993-17534
FEATURES             Location/Qualifiers
     source          1..3482
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 11.99 cM"
     gene            1..3482
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /note="staphylococcal nuclease and tudor domain containing
                     1"
                     /db_xref="GeneID:56463"
                     /db_xref="MGI:MGI:1929266"
     exon            1..295
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            296..445
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            446..566
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            567..645
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            646..806
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            807..898
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1057
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1164
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1255
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1369
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1459
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1560
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1671
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1744
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1886
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..1996
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            1997..2185
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            2186..2327
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            2328..2451
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2521
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            2522..2635
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            2636..2839
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            2840..2884
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     exon            2885..3482
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3447..3452
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /note="hexamer: AATAAA"
     polyA_site      3471
                     /gene="Snd1"
                     /gene_synonym="Tudor-SN"
                     /note="major polyA site"
ORIGIN      
        1 gcttgcgcgg cgagtagaac gtgtggcggc ggcggagatc gcgtctcctc ttttgctccc
       61 agtcccgctg gtgttctagt gtgcgcctgg cgcttctgtc cagcccaccg acggtagcct
      121 gtcgcctgcc tgctccttgt cgctgcaagc gccgacaccc accctgacac ttccagtccg
      181 gccggccgcc ccactcgctg cctttccagc tccacacatg gcctcctccg cgcagagcag
      241 cggctcctcc gggggacccg cggtccccac cgtgcagcgg ggcatcgtca agatggtcct
      301 ctctgggtgc gccataattg tccgagggca gccccggggt ggtcctcctc ctgagaggca
      361 gatcaacctc agcaacattc gagctggaaa tcttgcccgt cgggcagctg ccacacaacc
      421 agatgggaag gacaccccgg atgagccctg ggcatttcct gcccgagagt tccttcgcaa
      481 gaagctgatt gggaaagaag tctgtttcac gatagaaaac aagactcccc agggacgaga
      541 gtatgggatg atctacctag gaaaagatac taatggggaa aacattgcag agtcgctagt
      601 tgcagaaggc ttggccaccc ggagagaagg catgagagcc aacaacccag agcagaaccg
      661 gctttcagaa tgcgaggaac aagcaaaggc atcgaagaaa gggatgtgga gtgagggcaa
      721 cggttcacac accatccggg acctcaagta caccattgag aacccaaggc actttgtgga
      781 ctcacaccac cagaagccag tcaatgctat cattgagcat gttcgagacg gcagtgtggt
      841 ccgggccctg ctccttccag gtcaccacct tgtcaccgtc atgctctcag ggattaagtg
      901 cccaaccttc cgtcgggaaa cagatgggag tgaaacgccg gagcccttcg ctgcagaagc
      961 caagtttttc accgagtctc gactgcttca gagagatgtt cagatcattc tggagagctg
     1021 ccacaatcag aaccttctgg gtaccatcct ccacccgaat ggtaacatca ctgaactcct
     1081 cctgaaggaa ggttttgccc gctgtgtgga ctggtcaatt gcagtttaca cccggggtgc
     1141 agaaaagctg agggcagctg agaggtttgc caaggagcgc aggctgagaa tatggagaga
     1201 ctatgtgcct cccactgcta atttggacca aaaggacaag cagttcgttg ccaaggtcat
     1261 gcaggttttg aatgctgatg ccattgttgt gaagctgaat tctggagact acaagaccat
     1321 ccacctgtca agcatccgac caccaaggtt ggagggagac aacatacagg ataagaacaa
     1381 gaagctccgg cccctgtatg acatccccta catgtttgag gcccgcgaat ttcttcgaaa
     1441 aaagctcatt gggaagaagg tcaatgtgac tgtggactac attagaccag ccagcccagc
     1501 cacagaaacg gtgcctgcct tttccgagcg tacctgtgcc actgtcacca ttggaggaat
     1561 aaacattgct gaggccctcg tcagcaaagg cctggccaca gtgatcagat accggcagga
     1621 tgacgaccag aggtcttcac actacgatga gctgctagct gcagaggcca gagctattaa
     1681 gaatggcaaa ggattacaca gcaagaagga ggtgcccatc caccgagttg cagacatttc
     1741 tggggacacc cagaaagcaa agcagttcct gccctttctt cagcgggcag gccgttctga
     1801 ggctgtggtg gagtatgtct tcagtggctc tcgcctcaag ctctatttac ctaaggagac
     1861 ctgcctcatc accttcctgc tggccggcat tgaatgtccc agaggagcac ggaatctccc
     1921 gggcttggtg caggaaggag agccattcag cgaggaggcc acacttttca ccaaggaact
     1981 agtgctgcag cgagaggtgg aggtagaggt agagagcatg gataaggctg gcaacttcat
     2041 tggctggctg cacatggatg gggctaacct gtctgtcctg ctggtggagc aagcgctgtc
     2101 caaggtccac ttcactgctg agcgcagtgc ctactacaag cctctcctgt ctgctgagga
     2161 agctgccaag cagaggaaag agaaggtctg ggcccactat gaggagcggc ctgtggagga
     2221 ggtcatgcct gtgctggagg agaaggagcg ctctgccagc tacaagccgg tgtttgtgac
     2281 cgagatcaca gatgacctgc acttctatgt gcaagatgtg gagactggca cccagctgga
     2341 aaagctgatg gagaacatgc gcaatgacat ctccagtcac cctcctgttg aggggtccta
     2401 tgccccccgc cggggagagt tctgcattgc caaatttgta gatggagaat ggtaccgcgc
     2461 ccgggtagaa aaggtggagt cccctgccaa agtgcatgtc ttctacatcg actacggcaa
     2521 cagagagatc ctgccatcca cccgcctggg caccctacca cctgccttca gcacgcgtgt
     2581 attgccagct caagccacag agtatgcctt cgccttcatc caggtgcccc aagatgagga
     2641 cgctcgcaca gatgctgtgg acagtgtggt gcgggacatc caaaacactc agtgcctgct
     2701 caacgtggag cacctgagcg ccagctgccc ccatgtcact ctgcagtttg cagattccaa
     2761 gggcgatgtg ggactgggcc tggtgaagga agggctggtc atggtggagg tgcgcaagga
     2821 gaagcagttc cagaaagtga tcacagaata cctgaatgcc caggaatcag ccaagagtgc
     2881 caggctgaac ctgtggcgct atggagactt ccgcgctgat gacgctgatg agtttggcta
     2941 cagtcgctaa ggagaacttg cctggccccc agcaccgctg atgccagacc ttctcccgct
     3001 gccaggaagc tgttgtcgac tccagacctg gttgagggag tatagattgg gtctagcttg
     3061 cttcagtgta cagaaacctc ctctgtcgtg gctagcattg aagctggggt ggagaacccg
     3121 aggttagttg ggggcagacc cgcacagtgg taatgccgtc cagtctctcc cagatgattt
     3181 tgtattttta tttggggaga gggggctggt tttttttttt tttttaattg tcttcaaatc
     3241 aggaaagaac catgaaagac tttgtgttag tgaagggtat aaccgtgaca cagaggcagc
     3301 tgtcagctgg cacccacctc gtcccccaga ccacccttct tcccaagtgt tgattatgtg
     3361 acttctgata catccgttct caaactccgg tgtgcccaca tctgcctcct caccagcctg
     3421 gtctgtattt aaagcttttg agacccaata aaatagtacc tgctgtctgc agccttactg
     3481 tc
//
