LOCUS       NM_011430                757 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus synuclein, gamma (Sncg), mRNA.
ACCESSION   NM_011430
VERSION     NM_011430.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Butts,J.C., Wu,S.R., Durham,M.A., Dhindsa,R.S., Revelli,J.P.,
            Ljungberg,M.C., Saulnier,O., McLaren,M.E., Taylor,M.D. and
            Zoghbi,H.Y.
  TITLE     A single-cell transcriptomic map of the developing Atoh1 lineage
            identifies neural fate decisions and neuronal diversity in the
            hindbrain
  JOURNAL   Dev Cell 59 (16), 2171-2188 (2024)
   PUBMED   39106860
REFERENCE   2  (bases 1 to 757)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 757)
  AUTHORS   Vargas,K.J., Colosi,P.L., Girardi,E., Park,J.M., Harmon,L.E. and
            Chandra,S.S.
  TITLE     alpha-Synuclein colocalizes with AP180 and affects the size of
            clathrin lattices
  JOURNAL   J Biol Chem 299 (9), 105091 (2023)
   PUBMED   37516240
REFERENCE   4  (bases 1 to 757)
  AUTHORS   Qu,F., Li,W., Xu,J., Zhang,R., Ke,J., Ren,X., Meng,X., Qin,L.,
            Zhang,J., Lu,F., Zhou,X., Luo,X., Zhang,Z., Wang,M., Wu,G., Pei,D.,
            Chen,J., Cui,G., Suo,S. and Peng,G.
  TITLE     Three-dimensional molecular architecture of mouse organogenesis
  JOURNAL   Nat Commun 14 (1), 4599 (2023)
   PUBMED   37524711
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 757)
  AUTHORS   Fernandez-Nogales,M., Lopez-Cascales,M.T., Murcia-Belmonte,V.,
            Escalante,A., Fernandez-Albert,J., Munoz-Viana,R., Barco,A. and
            Herrera,E.
  TITLE     Multiomic Analysis of Neurons with Divergent Projection Patterns
            Identifies Novel Regulators of Axon Pathfinding
  JOURNAL   Adv Sci (Weinh) 9 (29), e2200615 (2022)
   PUBMED   35988153
REFERENCE   6  (bases 1 to 757)
  AUTHORS   Alimova-Kost,M.V., Ninkina,N.N., Imreh,S., Gnuchev,N.V., Adu,J.,
            Davies,A.M. and Buchman,V.L.
  TITLE     Genomic structure and chromosomal localization of the mouse persyn
            gene
  JOURNAL   Genomics 56 (2), 224-227 (1999)
   PUBMED   10051410
REFERENCE   7  (bases 1 to 757)
  AUTHORS   Ninkina,N.N., Privalova,E.M., Pinon,L.G., Davies,A.M. and
            Buchman,V.L.
  TITLE     Developmentally regulated expression of persyn, a member of the
            synuclein family, in skin
  JOURNAL   Exp Cell Res 246 (2), 308-311 (1999)
   PUBMED   9925745
REFERENCE   8  (bases 1 to 757)
  AUTHORS   Buchman,V.L., Hunter,H.J., Pinon,L.G., Thompson,J., Privalova,E.M.,
            Ninkina,N.N. and Davies,A.M.
  TITLE     Persyn, a member of the synuclein family, has a distinct pattern of
            expression in the developing nervous system
  JOURNAL   J Neurosci 18 (22), 9335-9341 (1998)
   PUBMED   9801372
REFERENCE   9  (bases 1 to 757)
  AUTHORS   Lavedan,C.
  TITLE     The synuclein family
  JOURNAL   Genome Res 8 (9), 871-880 (1998)
   PUBMED   9750188
  REMARK    Review article
REFERENCE   10 (bases 1 to 757)
  AUTHORS   Buchman,V.L., Adu,J., Pinon,L.G., Ninkina,N.N. and Davies,A.M.
  TITLE     Persyn, a member of the synuclein family, influences neurofilament
            network integrity
  JOURNAL   Nat Neurosci 1 (2), 101-103 (1998)
   PUBMED   10195122
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AA690669.1 and BC028508.1.
            
            On May 16, 2009 this sequence version replaced NM_011430.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC028508.1, AF017255.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 AA690669.1         117-125
            10-757              BC028508.1         1-748
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 20.81 cM"
     gene            1..757
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /note="synuclein, gamma"
                     /db_xref="GeneID:20618"
                     /db_xref="MGI:MGI:1298397"
     exon            1..210
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..461
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /codon_start=1
                     /product="gamma-synuclein"
                     /protein_id="NP_035560.1"
                     /db_xref="CCDS:CCDS26937.1"
                     /db_xref="GeneID:20618"
                     /db_xref="MGI:MGI:1298397"
                     /translation="MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKT
                     KENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVANKTVEEAENIVVTTGVVRKEDLEP
                     PAQDQEAKEQEENEEAKSGED"
     exon            211..252
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /inference="alignment:Splign:2.1.0"
     exon            253..380
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /inference="alignment:Splign:2.1.0"
     exon            381..440
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /inference="alignment:Splign:2.1.0"
     exon            441..732
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /inference="alignment:Splign:2.1.0"
     regulatory      709..714
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /note="hexamer: AATAAA"
     polyA_site      732
                     /gene="Sncg"
                     /gene_synonym="persyn"
                     /note="major polyA site"
ORIGIN      
        1 caataagagg cagtagcagc agagacagcg gctgcggcag cactccagtc catagcttgc
       61 agcagccagg ttccatcctt gcaaacacca tggacgtctt caagaaaggc ttctccattg
      121 ccaaggaagg tgttgtgggt gctgtagaaa agaccaagca gggagtaacg gaggcagctg
      181 agaagaccaa ggagggggtt atgtatgtgg gcaccaaaac caaggagaac gtggtacaaa
      241 gtgtcacctc agtggctgag aagaccaagg agcaggccaa tgccgtgagt gaagctgtgg
      301 tcagcagcgt caacacagtg gccaacaaga ccgtggagga ggctgaaaac atcgtggtca
      361 ccaccggggt ggtgcgcaag gaggacttgg aaccccctgc acaggaccaa gaagccaaag
      421 agcaagagga gaatgaagag gccaagagtg gagaagacta gaaggctgcc agccaaccac
      481 agaggctcaa gggacacccc tctgccttgg accctgtctc aacctggcac actgaatgcc
      541 ctgcctagag tgccctgcag gttgcccaag ttctctgtcc ctagcccagt gccacaagtc
      601 cacacacgct actgccagcg ccagcacccc ctgctggctc cttttaccct atggtcctct
      661 gatcaccaat cagatgctgc tgtgatttct ttttttttaa tgattccaaa taaaacctga
      721 gccccactcc caaaaaaaaa aaaaaaaaaa aaaaaaa
//
