LOCUS       NM_001406731            4381 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus small nuclear RNA activating complex, polypeptide 4
            (Snapc4), transcript variant 3, mRNA.
ACCESSION   NM_001406731 XM_006497903
VERSION     NM_001406731.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4381)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4381)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4381)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 4381)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 4381)
  AUTHORS   Garcia-Frigola,C., Burgaya,F., Calbet,M., Lopez-Domenech,G., de
            Lecea,L. and Soriano,E.
  TITLE     A collection of cDNAs enriched in upper cortical layers of the
            embryonic mouse brain
  JOURNAL   Brain Res Mol Brain Res 122 (2), 133-150 (2004)
   PUBMED   15010206
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732541.11.
            
            On May 20, 2022 this sequence version replaced XM_006497903.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14777535.58925.1,
                                           SRR17253014.2187082.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                AL732541.11        145687-145776
            91-233              AL732541.11        147689-147831
            234-280             AL732541.11        148258-148304
            281-448             AL732541.11        149289-149456
            449-574             AL732541.11        149600-149725
            575-653             AL732541.11        150092-150170
            654-735             AL732541.11        150636-150717
            736-840             AL732541.11        151578-151682
            841-913             AL732541.11        151761-151833
            914-1078            AL732541.11        152140-152304
            1079-1226           AL732541.11        152859-153006
            1227-1333           AL732541.11        153245-153351
            1334-1428           AL732541.11        153500-153594
            1429-1523           AL732541.11        155445-155539
            1524-1603           AL732541.11        156334-156413
            1604-2077           AL732541.11        156713-157186
            2078-2342           AL732541.11        157917-158181
            2343-2413           AL732541.11        158520-158590
            2414-2524           AL732541.11        159024-159134
            2525-2552           AL732541.11        159889-159916
            2553-3970           AL732541.11        160288-161705
            3971-4125           AL732541.11        162533-162687
            4126-4381           AL732541.11        163305-163560
FEATURES             Location/Qualifiers
     source          1..4381
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 18.87 cM"
     gene            1..4381
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /note="small nuclear RNA activating complex, polypeptide
                     4"
                     /db_xref="GeneID:227644"
                     /db_xref="MGI:MGI:2443935"
     exon            1..90
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            91..233
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..4105
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /note="isoform 3 is encoded by transcript variant 3;
                     snRNA-activating protein complex 190 kDa subunit; SNAPc
                     subunit 4"
                     /codon_start=1
                     /product="snRNA-activating protein complex subunit 4
                     isoform 3"
                     /protein_id="NP_001393660.1"
                     /db_xref="GeneID:227644"
                     /db_xref="MGI:MGI:2443935"
                     /translation="MDIDAEREKITQEIQELERILYPGSTSVHFEVSESSLSSDSEAD
                     SLPDEDLETAGAPILEEEGSSESSNDEEDPKDKALPEDPETCLQLNMVYQEVIREKLA
                     EVSQLLAQNQEQQEEILFDLSGTKCPKVKDGRSLPSYMYIGHFLKPYFKDKVTGVGPP
                     ANEETREKATQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKLLKLEYLHEK
                     QSRVSSELERQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGARS
                     AEEIRKFWQSSEHPSISKQEWSTEEVERLKAIAATHGHLEWHLVAEELGTSRSAFQCL
                     QKFQQYNKTLKRKEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWT
                     KSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFS
                     LKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQRK
                     RGQRPRHSSQWSSSGSSSSSSEDYGSSSGSDGSSGSENSDVELEASLEKSRALTPQQY
                     RVPDIDLWVPTRLITSQSQREGTGCYPQHPAVSCCTQDASQNHHKEGSTTVSAAEKNQ
                     LQVPYETHSTVPRGDRFLHFSDTHSASLKDPACKSHTLMKERPKQPLLPSSRSGSDPG
                     NNTAGPHLRQLWHGTYQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAPRRP
                     ATVQTKADSIRMQLECARLASTPVFTLLIQLLQIDTAGCMEVVRERKSQPPALLQPGT
                     RNTQPHLLQASSNAKNNTGCLPSMTGEQTAKRASHKGRPRLGSCRTEATPFQVPVAAP
                     RGLRPKPKTVSELLREKRLRESHAKKATQALGLNSQLLVSSPVILQPPLLPVPHGSPV
                     VGPATSSVELSVPVAPVMVSSSPSGSWPVGGISATDKQPPNLQTISLNPPHKGTQVAA
                     PAAFRSLALAPGQVPTGGHLSTLGQTSTTSQKQSLPKVLPILRAAPSLTQLSVQPPVS
                     GQPLATKSSLPVNWVLTTQKLLSVQVPAVVGLPQSVMTPETIGLQAKQLPSPAKTPAF
                     LEQPPASTDTEPKGPQGQEIPPTPGPEKAALDLSLLSQESEAAIVTWLKGCQGAFVPP
                     LGSRMPYHPPSLCSLRALSSLLLQKQDLEQKASSLAASQAAGAQPDPKAGALQASLEL
                     VQRQFRDNPAYLLLKTRFLAIFSLPAFLATLPPNSIPTTLSPDVAVVSESDSEDLGDL
                     ELKDRARQLDCMACRVQASPAAPDPVQSHLVSPGQRAPSPGEVSAPSPLDASDGLDDL
                     NVLRTRRARHSRR"
     exon            234..280
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            281..448
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            449..574
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            575..653
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            654..735
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            736..840
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            841..913
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1078
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1226
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1333
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1428
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1523
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1603
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..2077
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2078..2342
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2343..2413
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2414..2524
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2552
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2553..3970
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3971..4125
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4126..4381
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4346..4351
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4381
                     /gene="Snapc4"
                     /gene_synonym="5730436L13Rik"
                     /note="major polyA site"
ORIGIN      
        1 actgacttcc gcgactgcta gaagcatgat ctgcgtgtgg tcgcccgggc gatgatgcca
       61 gctgtgaagt ttggaaggga tgcctagaag gcaggctgaa gccatggaca tagacgccga
      121 acgagagaaa ataacacagg agatccagga gcttgaaagg attttgtatc ctggatccac
      181 cagcgtccac tttgaagtct ctgaatccag tctcagttca gactctgaag cagattcgct
      241 gcctgatgag gacttggaaa ctgctggtgc ccccatcttg gaagaggaag ggtcgagtga
      301 gagcagcaat gatgaggagg accccaagga caaagctctc cctgaagacc ccgagacctg
      361 tctgcagcta aatatggtct accaggaggt gatccgggaa aagctagcag aggttagcca
      421 gttgctagcc cagaaccagg agcagcagga agagatcctg tttgatctgt ctggaaccaa
      481 atgccccaag gtgaaggatg gcagaagtct gccctcatac atgtacatag gccacttcct
      541 gaagccatac ttcaaggaca aggttactgg agtggggcct cctgccaacg aagaaacacg
      601 ggagaaggct acccagggaa tcaaggcctt tgaacagctc ttggtgacca agtggaagca
      661 ctgggagaaa gccttgctca ggaagtctgt agtgagtgac cgcctacaac gtctgcttca
      721 gcccaaattg ctgaagctgg agtacttaca cgaaaaacag agccgagtct ccagtgagtt
      781 ggaaaggcag gccctggaga agcagattaa ggaagcagag aaggagattc aggacatcaa
      841 ccagctccca gaggaagcat tgttggggaa ccggctagac agccacgact gggagaagat
      901 ttccaatatt aactttgaag gagcccgcag tgcagaggag atccggaagt tctggcagag
      961 ttctgagcat ccaagcatca gtaagcagga atggagcaca gaagaagtag agaggctgaa
     1021 ggccatcgct gccacacatg gccacctgga gtggcacttg gttgcagagg aacttgggac
     1081 aagccgcagt gcctttcagt gcctgcagaa attccagcag tacaacaaaa ccctgaaacg
     1141 caaggagtgg acagaagagg aagaccacat gctcacccag ctggtccaag agatgcgagt
     1201 tgggaaccat atcccatacc gcaagatcgt ctacttcatg gaagggagag actccatgca
     1261 gctgatctac cgttggacca agagcttaga tcccagcctg aaaaggggat tctgggcccc
     1321 agaggaagat gctaaattgc ttcaagctgt tgccaagtat ggggcgcagg actggtttaa
     1381 aatccgggaa gaggtgccag gtaggagcga tgcccaatgc agagaccgct acatcagaag
     1441 attacatttc agcttgaaaa agggacggtg gaatgcaaaa gaagaacaac agctgatcca
     1501 gctaatagag aaatatggtg ttggtcactg ggcaagaatc gcttctgaat tgccccatcg
     1561 gtcaggctcc cagtgtctga gcaagtggaa gatcttggcc aggaagaaac agcatctgca
     1621 gaggaagaga gggcagaggc cccgtcacag tagccagtgg agctctagcg gcagcagcag
     1681 cagcagcagt gaagactacg gcagcagcag tggcagcgac ggcagcagcg gcagtgaaaa
     1741 ctcagatgtg gagctggagg cgtctctgga gaagagtaga gcactgactc ctcaacagta
     1801 cagagtgcca gacattgacc tgtgggttcc taccaggctg atcaccagcc agtcacagag
     1861 agaagggaca gggtgctacc cacaacaccc tgctgtctcc tgctgcactc aggatgcctc
     1921 tcaaaatcac cacaaggaag gttctaccac cgtctctgct gctgagaaaa accagctgca
     1981 ggtgccctat gagacccaca gcactgttcc aagaggagac cggttcctac acttctcgga
     2041 cacccactca gcaagtttga aggatccggc ctgcaagagt cacacactga tgaaggaaag
     2101 accgaagcag ccactcctcc ctagttcacg ctcagggtct gaccctggca acaatacggc
     2161 tgggccccat ctgcggcagc tatggcatgg aacttaccag aataagcaga gacgcaagag
     2221 acaggctcta catcgcaggc tccttaagca caggcttttg ctggctgtga taccctgggt
     2281 gggtgacatc aacctggcct gcacacaagc tccccggaga cctgcaaccg ttcagactaa
     2341 agctgacagc atccggatgc agttagagtg tgcccgcctg gccagcactc cggtattcac
     2401 actgcttatt cagctattgc agattgatac tgcgggctgc atggaggtgg ttcgagagag
     2461 gaaaagccag ccccctgcac tgctccagcc tggcacccgg aacacccagc cgcatctcct
     2521 gcaggcatcc tctaatgcca agaacaacac aggctgcctc ccaagcatga cgggggaaca
     2581 aactgcaaag agagccagcc acaaagggcg cccacgactg gggtcatgca ggactgaggc
     2641 tacccccttc caagtccctg tagcagcccc acgtggcctc cggccaaagc ctaagactgt
     2701 ttctgagctg cttcgggaga agcggctccg tgagtcccat gccaagaagg ccactcaggc
     2761 tcttggtctc aacagccagc tgctggtctc ctcacctgtg atcctccagc cccctctgct
     2821 gccagtcccc catggttccc cagtagtagg ccctgcaacg tccagtgtag aactctctgt
     2881 acctgtggcg ccggtgatgg tcagttcaag tccttctggc tcctggccgg tgggtgggat
     2941 ctcagccaca gacaagcagc cccccaacct acagaccatt tccctaaatc ctccccacaa
     3001 agggacccag gttgcagccc ctgctgcttt taggagccta gccttagccc ccgggcaagt
     3061 ccccacaggc ggccatctga gtactctagg acagacctct accacatccc agaagcagag
     3121 cctgcccaag gtcctgccca ttcttcgagc tgctcccagc ctcactcagc tgtctgtgca
     3181 gccaccagta agtggacagc ccctggcaac caagtccagc ctgcctgtca actgggttct
     3241 cacaactcag aagttgctct ctgtccaagt gccagctgtg gtgggcctcc cccagtcagt
     3301 gatgacccct gagaccatag gactacaagc aaaacagctg ccttcccctg ccaagactcc
     3361 tgcttttctg gaacagcctc cagccagtac agacacagaa cccaagggac ctcagggcca
     3421 ggaaatacca cccacacctg ggcccgaaaa ggcagctttg gacctaagtc tcctttccca
     3481 ggaaagtgag gcagccatcg tcacatggct gaaggggtgc caaggtgctt ttgtaccccc
     3541 gctggggagc aggatgccct atcatccccc ttccctgtgc agcttgcggg cattgtccag
     3601 cctcctcctc cagaaacagg acttggagca gaaggcttcc tctctggcgg ccagccaggc
     3661 agctggggcc caacctgatc ccaaggctgg agccctacaa gcttccctgg agctggtaca
     3721 gaggcaattc cgggacaacc cagcctacct cctgctaaag acgcgtttcc tggctatctt
     3781 ctcccttcct gcattcctgg ccactctgcc ccccaacagc atccccacca ccctgtcacc
     3841 agacgtggct gtggtttctg agagtgacag tgaagacctc ggtgacttgg agctcaagga
     3901 tagggctaga cagttggact gcatggcctg cagagtgcaa gcaagcccag cagccccaga
     3961 ccctgtacag agccaccttg tctcccctgg tcagagagct ccaagtcctg gtgaggtttc
     4021 tgctccctcc cctctggatg cttctgatgg ccttgatgac cttaacgtgc tcaggactcg
     4081 acgtgctcgg cattcccgga gatagaggtt gctttgagca gcaaggacaa ggcgtcaagg
     4141 ggtccagaat ccagctctca ctaggcaaga ggcagggccc aagcctgccc agaagcagta
     4201 cacaaccctc agcaagaaga cgggaagcca gaaagctgca ggctgaggac caagctgtcg
     4261 gtagcgatct acaggctgtg gtgatagcag tggccacgtg atcacaggct acctgttaac
     4321 agacttgggg ccgtgtatgt gagggaataa aggaaatgcc taattttcac ttaaaaagca
     4381 a
//
