LOCUS       NM_178392               6400 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus small nuclear RNA activating complex, polypeptide 1
            (Snapc1), transcript variant 1, mRNA.
ACCESSION   NM_178392
VERSION     NM_178392.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6400)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6400)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124712.5 and AC161591.2.
            
            On Mar 15, 2023 this sequence version replaced NM_178392.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784644.1068314.1,
                                           SRR17253012.9175854.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               AC124712.5         146042-146291
            251-410             AC124712.5         149453-149612
            411-551             AC124712.5         149784-149924
            552-656             AC124712.5         151072-151176
            657-815             AC124712.5         151726-151884
            816-884             AC124712.5         153430-153498
            885-947             AC124712.5         154082-154144
            948-1098            AC124712.5         156556-156706
            1099-1200           AC124712.5         164023-164124
            1201-4925           AC124712.5         165408-169132
            4926-6400           AC161591.2         146141-147615       c
FEATURES             Location/Qualifiers
     source          1..6400
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 32.0 cM"
     gene            1..6400
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /note="small nuclear RNA activating complex, polypeptide
                     1"
                     /db_xref="GeneID:75627"
                     /db_xref="MGI:MGI:1922877"
     exon            1..250
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1235
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     snRNA-activating protein complex subunit 1; SNAPc subunit
                     1; SNAPc 43 kDa subunit; snRNA-activating protein complex
                     43 kDa subunit"
                     /codon_start=1
                     /product="snRNA-activating protein complex subunit 1
                     isoform 1"
                     /protein_id="NP_848479.1"
                     /db_xref="CCDS:CCDS25978.1"
                     /db_xref="GeneID:75627"
                     /db_xref="MGI:MGI:1922877"
                     /translation="MGTPAGAGTRPTGAGTVEGVGIPPGLQTDYETLLSRFQEMDSVR
                     FEDFTELWRSMKFATIFCGKMRNLKKNMFTKEALALAWRYFLPPHTFQIRVGALYLLY
                     GLYNTQLCQPKQKIRVALKDWDEVIRFQQDLMNAQHFDAAFVFRKLRLDRAFHFTAMP
                     KLLSCRMKKKVQQTEVTQKFKDPNDRVMKLITSDVLEEMLNVHDHYQNMKHAISADKS
                     MPDRALSLVKEDFFENIKNIVLEHQEWHKERKNPSLKPKLKDGEENGEGSSEEPERCE
                     RAVSLAKIKAKAFSAVVPVSKSRRHRQSKLDSSDSDSGSGQVQGRAAKRKRTREPAGP
                     AGRKRSSRSKGNAPNERKEEKSLHLSMPIITEEEEEDMGGVRKAEFTAPKRKRKC"
     exon            251..410
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            411..551
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            552..656
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            657..815
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            816..884
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            885..947
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1098
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1200
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..6400
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1704..1709
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1729
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /note="major polyA site"
     regulatory      6071..6076
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6094
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
     regulatory      6280..6285
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      6304
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
     regulatory      6378..6383
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      6400
                     /gene="Snapc1"
                     /gene_synonym="2700033G17Rik; 9630050P21Rik"
ORIGIN      
        1 gtgactgggg cggtgctaca gggccttctg ggcattgggg aagccgggtc cgggagagag
       61 tgagcatggg gactcctgcg ggcgccggga cccgtcccac gggcgctgga actgttgaag
      121 gcgtggggat ccctccgggc ctgcagactg actacgagac gctgctcagc cgcttccaag
      181 agatggacag cgtgcgcttc gaggacttca cggagctctg gcgcagcatg aagttcgcga
      241 ccatcttctg tggcaaaatg aggaatttaa aaaagaacat gtttacaaag gaagctttag
      301 ctttggcgtg gcgctacttt ttgcctccac acacgttcca gatcagagtt ggcgctttgt
      361 atcttctgta cgggttgtac aacacacagc tgtgccagcc gaaacaaaag atccgagttg
      421 ccttgaagga ctgggatgaa gtcatcaggt ttcagcaaga cttgatgaac gcacagcatt
      481 tcgacgcggc ttttgttttc aggaagcttc ggctggacag agccttccac ttcacagcta
      541 tgcccaagct gctttcgtgt agaatgaaga aaaaagttca acaaactgaa gtgacacaga
      601 aatttaagga cccgaatgat cgtgtaatga aacttatcac ttctgatgta ttagaggaaa
      661 tgctgaatgt tcacgatcat tatcaaaata tgaagcatgc tatttcagca gacaagtcca
      721 tgccagacag agctctcagt ctggtaaagg aggacttttt tgagaacatt aagaacatag
      781 ttttggagca tcaggagtgg cacaaggaac ggaagaatcc ctccttaaaa cccaaactta
      841 aagatggaga agagaacggt gaaggctctt cagaggagcc agagagatgt gagagagctg
      901 tgtctttagc gaaaataaaa gcgaaagcct tttcagctgt tgtcccggtg tccaagtcca
      961 ggaggcatcg ccagtccaag cttgactctt ctgactctga ctctgggtct ggacaagtgc
     1021 aaggcagagc agctaagaga aagagaacca gagaaccagc aggaccagca ggaaggaaga
     1081 gatcttccag aagcaaaggt aacgctccga atgaacgtaa ggaagagaag tcgttacacc
     1141 tgagtatgcc tattattaca gaggaggagg aggaggacat gggtggcgtc agaaaagcag
     1201 agttcactgc gcccaagagg aagagaaaat gctgaaccgg gaggctggtg gagttttaaa
     1261 ttttgagctt tccaacagaa gaaaggtgtc atgtgttcta agcaggaagt agccagtgaa
     1321 gactggatct gagaacaagc tcatttctgt gagatggaag agcatgccat aggccaagag
     1381 ttgagtaaag gtttactctg aagattaatt ttaacatttt tgttaatatt gcaattttaa
     1441 caaattacat tgtagtttgt tacagaatag attgtaaatg tgttaaactt gttagacttg
     1501 ttaggggtct gtatgagtgg agatagagtt tctattgcct tcagaatgta atagaaagaa
     1561 ttacatattt gtgagttagt actctttcct gaaagttttt gtgctgtact aatgcattta
     1621 tatataaatg attcatacct gtcacctagc aacggatttg gctggggttt ttgttgaata
     1681 ttttgtgtgt tatggttaag tgcaataaaa attttgcccc cttgttttat cttctagtgt
     1741 gtgaaatttt catggccaat aacttgactg ataccttagt aagttacggc tgccttcgtg
     1801 cttacgatgt acccttactt cctcattgat ttggacaggg tctgcctgtg tatgctaggc
     1861 tggccttgaa ctctccatgc gagtactgcc ttgctcggcc tccccactgc tgggattata
     1921 gataatgcac cgccgggcct cactccttac cctctgtagt atttgcttta aagttcccat
     1981 tggtctactg tatatgaatg cataggtacc tgtgtgtgtg tccttgtcta cacataagat
     2041 taattaatac actgtttaat gcttatgtac tgtctaatag gcccatagga gcagtcatgt
     2101 agattctgaa acgtgtcttt gacacagaac ttttgtaaat cacagaaaag atgtctctag
     2161 tcacgtgtgt gctgctgttt taatttcaca cccctggagt tttaagtgga gatggcttta
     2221 gctgtgcttg aaagctgcca acacacggcc tctgtgttgt gaggctaatg cagcctgaca
     2281 tatagttaat tattaaggct caaaggctgg cttgaagagg taatttccaa gtctgatatg
     2341 attgaaaatg tatatcttag gtatgtaata tgttaagacc aaaatactga tgttggcttg
     2401 gataatactt gacatcgtta tcctgttagc tactaaaaag cagttgtttc ctgtgtctga
     2461 cttcagctct gtccgataat gggttggaca ttacagtgtg aacatgggcc agagctgctg
     2521 ggctgcaaca ccagagcttg gttagtaata tgtagctgag tggattagca ttgtacagct
     2581 gaaacgctat gtacctgagt cgtaatctat ttttcacaaa gcgcttataa aagaccatgg
     2641 tgtcatttca cagacaaagg gatggtgagt agcaaacagt gttgtcatag taaccgaaag
     2701 tttgtgtttg cccagctccc tgagttgatc aggctaacct gtggttcact ccacagctga
     2761 agggaaccct cattaccttg tgtcaatttt aattaggtat aatgaatacc atcttctcag
     2821 actaccttgg gtatagtgaa agactggtac ctctgtctgt ttatctgtct acttacgtgt
     2881 ctacctatgt cttgagaaaa taccttaaaa acaaactttg cactgaaagt tacttttatt
     2941 tttctcaggt tagctttgga aaataactgt agttactaat gccttcctta cccttcattc
     3001 ttgaattaaa ttacagtttg aagaaggctt actttttaaa tggcttagaa agaactctgt
     3061 gggtgttaaa actattcaca ttttcattta tcttttgagc gactatgtag taattttcat
     3121 tgcacatttt tcttattctc tgtgttaata taaatgtcaa agcccagact tgaggttgta
     3181 taatcccttt tatgtgatat ttttaaatgt ctgaattatt cattctactg tgctgtgtat
     3241 tacaggtctg aatttttaag agacattcaa gcaggctcct ttcagttgca agaaacaaaa
     3301 gcatactccc actatcgtaa atgctgggag cttactggaa gattatggtt aaataagtaa
     3361 ggcactcatc aaagacagct tcctcaaggg tttgggaatt agctataggc ctctcttaac
     3421 accaaatgat gctcttagct agggtggaga tccaaatcag ttgtgtccca tgtaccagag
     3481 ggcatggcag atgacagaga aggacccatc tgtggcagct ttcctcagca aaggtgagaa
     3541 aggtcaggcc tttacagtct cacgggtttc tcagtgtagt cgtggtttga caaaatgcag
     3601 tgtcagcctt gcaccttcag gatgtagtta aagggacacg ctattccctt cacaggtaag
     3661 tcactgcaca gtggtgaagg acctcagctc tggggcaggc tgggtttgct ctggcattta
     3721 ataatttatg ccatctgtaa taatttgggg ctgcatatac tgtaacacat taatagactg
     3781 gcagaggctt caccagtgaa tgttttacac ccagtccttt gttacagttg gcaagttgcc
     3841 catgctggac ttgggattca ctgtgtagcc caggcacggc ttgaaccttc tatcctcctg
     3901 tctcactttc ccaagtaggt gggactacag actgccacct agcaacagtc ctgtgtttac
     3961 tcccgtaaat cgaacccact gctctttatt cctctgggaa agccgttggg agtagatctc
     4021 ggatggttcg ttttcagtct gaagaaatta atactgattt atttatatat atatcagcac
     4081 ggttgcagac cagttctatc atattttgtt tgtctgaaaa aatatcttca tttctgaatg
     4141 aaattgtttt tgcaagatgt agaattctag ttgtttcagc tctttccccc tttctgtcaa
     4201 cacttgcaag acttttttca ctccatcatc atcagcctgc tttgtctctg gcaggaaatt
     4261 agaatttgtt cctccagtcc ctcgtgtacc tcaatctttt tttctttgtg ttatattttt
     4321 gtctgtctgt ctgtctgtct gtctgtctgt ctgtctgtct atttgatggt gggacccatg
     4381 gccttcatat actaaccaca cgctctacca gaagttcctc caggccctcc ctggctgcct
     4441 gcaggctttg ttgtttgtta ttcagtctga tacaggtctg gtgtggttgg cttttctaac
     4501 ccatgatgca ttctgcactc tcctcacttg cttctctctc tgggacttga gccttgtttg
     4561 ctaattactt tgtactctct cttgggttgt attttgtttt ctccaataat acttcttcca
     4621 ttgcctcaga gtgccttttg atttcaagtt caccatcttt tcttctcttg tatccaatct
     4681 gctcttgatt ttctccgatg acttttcatc tggaagcacc gattgttggt tctgatttct
     4741 ccttgtcctt tccatcttca ttgaaatagt tcctttgtca ccttctctaa ccatttgtct
     4801 ttatgtagtt ggtggggtgg gggttgagac agggtccctc tgtctgtctg tctgtctgtc
     4861 tgtctaaaaa aaaactgctg ttctggaact tgctgggtag accaggctat cctgaaacag
     4921 agatccacct gtgtccagct ctgggattaa aggtgtgtgc caccacactc cgttgtcact
     4981 ttttaaaaat atggcacttt tactggaacg cagagtattt gttacatgaa tatatcctag
     5041 caggatttga actttctacg caggagcctc gtgagtctga agctgccgaa aactctgctt
     5101 ggtactttgt gatgtcagcc acttattagc cctagactca ctgtgtgatg ccagagagat
     5161 gaggggaatt tatactcagg tttggggtgg tgttgctggt ggctcttttc agagatttcc
     5221 aacccagctg ataatcagag aaagaaaact agttcataag atgacataaa ccctttcttc
     5281 caggttgctt ttgatcatga tcattattgc agtggtagaa gcaaactggg aagccttgtt
     5341 accagagaat tagagtatca tgttagcctc agcctttgag agaaggcgat gaaccggagt
     5401 tgtttatgta aatgtaattt taagtgatgt gattttgcta gagcttcagc agttgctaac
     5461 cgtttgttaa aggctttagg tggctggttt gtcttagttt cctgcaatgt ggttggtgca
     5521 tagcatccct tggtagcatc gttaggctgg caagggcttc accagtgaat gttttaaaac
     5581 cataaagcat agttagctga gcttacggtc tttgtaaact tcaactgttt ccttccacta
     5641 acagtgcaag aagatacttt gtgtattgta ttaaaaaatg aaataccctg tcttttaaaa
     5701 aacacggtat atctagaaaa tcatcttgtt tgcaatttga taggaaccaa tcaaaagatt
     5761 tcatttgtct tcagtgtgta acaaaacctt ttattaccag cgaagtgatc tatatgtatg
     5821 tgctaccagt gaataactct tattattttt ttccatgtgc tttcttagat ttacaaatat
     5881 gatttattcc cacgactgca gtctacagcg ctagaacaaa tgtctctgta atgtttctgg
     5941 gtctgtgtaa ttaggattta attgctttgg agaggaaatg ggagtgtaga ctgtctcctt
     6001 ggggctgtat tacagaattt cattttgttt tattctttgg tggatttatt ttttccctga
     6061 tattaacatt aataaagtga gcagaggatt ctaaccaatt gtgctggctg gatggctaca
     6121 ggaaatgaga cagggcaggt gtgggcttcc tgtaagacct tgtcgagccc agaacttgtg
     6181 gcaccagagg gagggtctag gtccagcagg gtcatagttc tagccactta gttttaaatt
     6241 tatattttat gtattttata tgttaatgta aaatataaaa ttaaaattta atttatattt
     6301 aaaattttgt ttttattttt gagagcttta ttaatgagat atctttgata gtgttctgtg
     6361 atcattttct gtatttcatt aaaagattca agcagaggta
//
