LOCUS       NM_001356452            1941 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus synaptosomal-associated protein, 47 (Snap47),
            transcript variant 1, mRNA.
ACCESSION   NM_001356452 XM_006534021
VERSION     NM_001356452.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1941)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1941)
  AUTHORS   Urbina,F.L., Menon,S., Goldfarb,D., Edwards,R., Ben Major,M.,
            Brennwald,P. and Gupton,S.L.
  TITLE     TRIM67 regulates exocytic mode and neuronal morphogenesis via
            SNAP47
  JOURNAL   Cell Rep 34 (6), 108743 (2021)
   PUBMED   33567284
  REMARK    GeneRIF: TRIM67 regulates exocytic mode and neuronal morphogenesis
            via SNAP47.
REFERENCE   3  (bases 1 to 1941)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1941)
  AUTHORS   Corradini,I., Donzelli,A., Antonucci,F., Welzl,H., Loos,M.,
            Martucci,R., De Astis,S., Pattini,L., Inverardi,F., Wolfer,D.,
            Caleo,M., Bozzi,Y., Verderio,C., Frassoni,C., Braida,D.,
            Clerici,M., Lipp,H.P., Sala,M. and Matteoli,M.
  TITLE     Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice
            are normalized by antiepileptic drugs
  JOURNAL   Cereb Cortex 24 (2), 364-376 (2014)
   PUBMED   23064108
REFERENCE   5  (bases 1 to 1941)
  AUTHORS   Jurado,S., Goswami,D., Zhang,Y., Molina,A.J., Sudhof,T.C. and
            Malenka,R.C.
  TITLE     LTP requires a unique postsynaptic SNARE fusion machinery
  JOURNAL   Neuron 77 (3), 542-558 (2013)
   PUBMED   23395379
REFERENCE   6  (bases 1 to 1941)
  AUTHORS   Holt,M., Varoqueaux,F., Wiederhold,K., Takamori,S., Urlaub,H.,
            Fasshauer,D. and Jahn,R.
  TITLE     Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous
            expression
  JOURNAL   J Biol Chem 281 (25), 17076-17083 (2006)
   PUBMED   16621800
  REMARK    GeneRIF: SNAP-47 is a novel Qbc-SNARE with ubiquitous expression
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY104758.1, CD363532.1, AK049330.1 and AI842642.1.
            
            On Oct 5, 2017 this sequence version replaced XM_006534021.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoforn (1). Variants 1 and 2
            encode the same isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC029025.1, SRR5189670.125452.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-98                BY104758.1         1-98
            99-679              CD363532.1         1-581
            680-1916            AK049330.1         643-1879
            1917-1941           AI842642.1         1-25                c
FEATURES             Location/Qualifiers
     source          1..1941
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.7 cM"
     gene            1..1941
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /note="synaptosomal-associated protein, 47"
                     /db_xref="GeneID:67826"
                     /db_xref="MGI:MGI:1915076"
     exon            1..120
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /inference="alignment:Splign:2.1.0"
     exon            121..659
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..1404
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /note="isoform 1 is encoded by transcript variant 1;
                     synaptosomal-associated 47 kDa protein"
                     /codon_start=1
                     /product="synaptosomal-associated protein 47 isoform 1"
                     /protein_id="NP_001343381.1"
                     /db_xref="CCDS:CCDS24767.1"
                     /db_xref="GeneID:67826"
                     /db_xref="MGI:MGI:1915076"
                     /translation="MSSDMRVHSWSCSYYLDLEKQWVSGKLTLTPHSLKFIVEKTEEV
                     LVGLPLSSIIEIRKESSLFIFGAITVLEKGQTKHWFSSLQPSRNVVFNVIEHFWRELL
                     LSQPGTAANIPSHVTRGQELIGLMANSQKRMEDTAKDLQQQSEQLDSVLKGLEKMESD
                     LDVADRLLTELETPSWWPFGSKFWKMPAEENLKEGVSSTCEPFGKEGVVITVPAIISE
                     RAESHSKLGKLTVLVSALEIYDSCSLLLHRFEKEDVDDIKVHSPYEVSIRQRFIGKPD
                     VAYQLISAKMPEVIPILEVQFSSKIELLEDALVLRNKVFASSAERHAASRPKGCTPHR
                     ELPTGGQEGEQLQLQKNLPLFSEGEAQELTQILSKMKGLALDTEAELERQDAALDGIT
                     VAVDRATLNVDKQNRRMRKLM"
     exon            660..1132
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1257
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1927
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1898..1903
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /note="hexamer: AATAAA"
     polyA_site      1925
                     /gene="Snap47"
                     /gene_synonym="1110031B06Rik; SNAP-47"
                     /note="major polyA site"
ORIGIN      
        1 tctcgcgcag gcgtacaagc gctcgccgag tggctgacct gctccccagc tgctggcgtc
       61 tctgtctggt ggtccagtgg agcgtgccat tgcgtcttct gcgtgctcct cttgcctcag
      121 cagatactgc agcctctggg tagcccagca acctaggaac agatgagttc tgatatgcgt
      181 gtccactcct ggtcttgttc ctactatctg gaccttgaga agcaatgggt ttctggaaaa
      241 ctgaccctga ctcctcattc actgaagttc attgtggaaa aaacagaaga ggtccttgtt
      301 ggcctgcccc tctccagcat cattgagatc aggaaagagt catctctctt tatcttcggt
      361 gcgatcacag tcctggagaa gggccagacc aagcactggt tcagctcact gcagcctagt
      421 cgaaatgtgg tcttcaacgt catcgaacat ttctggaggg agctgctact gtcccagcca
      481 ggcactgctg ccaacatacc ctcccacgtg accaggggac aggagctgat aggactgatg
      541 gcaaattccc agaaacgcat ggaagacaca gcgaaggatc tccagcagca gagcgaacag
      601 ctggacagcg tcctgaaggg cctggagaag atggagtccg acctggacgt ggctgacaga
      661 ttgctgacag aattggagac accttcctgg tggccttttg gctctaagtt ttggaagatg
      721 ccggcagaag aaaatctcaa ggaaggtgtg tcttccactt gtgagccctt tggaaaggaa
      781 ggggttgtga tcacggtccc tgctattatt tctgagagag cagagtctca ttccaagctg
      841 ggaaagctca ctgtcctggt ctccgctctg gaaatctatg actcctgctc gttgctcctg
      901 cacagatttg agaaggaaga tgttgatgat atcaaggttc actctcctta tgaggtcagc
      961 atacgccagc gcttcattgg gaagccagac gtggcttacc agctgatatc tgccaagatg
     1021 ccagaggtca ttcccatctt agaagtgcag ttcagcagca agattgagct cctggaagac
     1081 gccttagtgc tcaggaacaa ggtctttgct tcctctgcag agaggcatgc agcatccaga
     1141 ccgaagggct gcactccaca ccgagagctg cccacaggag gacaggaagg cgagcagctg
     1201 cagctgcaga agaacttgcc actgttctct gagggggaag cccaggagct gacacagatc
     1261 ctgagcaaaa tgaagggact cgcactggac actgaggcag agctggaacg ccaggatgcg
     1321 gctctggatg gcatcaccgt agctgtggac cgggcaaccc tgaatgtgga caagcaaaac
     1381 cggcgtatga gaaagctgat gtagtggggc aagctgtaaa cagccacccc tggcatggct
     1441 ctgctgattc tattgctatt agcccttttc ctttcccctg agacccggga agccattctg
     1501 ggtactgtga aactatgagg ccctacctgg gaactacacc ttcctaggat gggccaggag
     1561 aggccacaat atgcatgagc atgtatgttt cccggggccc taagcatgag ggccatgtcc
     1621 tgttcaggca agaatcgcca ccgtagcgta gccatccttc ctgtccacac tgagaccccg
     1681 gcgttgagct gccattgtgg catcatgttg tcacatcata ttgtcatctt ttcaccattt
     1741 ttgccaaaca gtagagaaaa atgtcagtca ttctggtctg gctctgccat ccacttgcca
     1801 gaaacatcaa ttcccccttc aaatgctgct gtagcccctg ccaccttttc ctgatcatca
     1861 gttagagttc tgtaaccagt agcctctgtg tgtgcgtaat aaaagaatgt ttattcgatg
     1921 acttacaaaa aaaaaaaaaa a
//
