LOCUS       NM_001412633            4287 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus synaptosomal-associated protein 23 (Snap23),
            transcript variant 11, mRNA.
ACCESSION   NM_001412633
VERSION     NM_001412633.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4287)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4287)
  AUTHORS   Huang,M., Chow,C.H., Gurdita,A., Harada,H., Pham Truong,V.Q.B.,
            Eide,S., Sun,H.S., Feng,Z.P., Monnier,P.P., Wallace,V.A. and
            Sugita,S.
  TITLE     SNAP-25, but not SNAP-23, is essential for photoreceptor
            development, survival, and function in mice
  JOURNAL   Commun Biol 7 (1), 34 (2024)
   PUBMED   38182732
  REMARK    GeneRIF: SNAP-25, but not SNAP-23, is essential for photoreceptor
            development, survival, and function in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4287)
  AUTHORS   Huang,M., Bin,N.R., Rai,J., Ma,K., Chow,C.H., Eide,S., Harada,H.,
            Xiao,J., Feng,D., Sun,H.S., Feng,Z.P., Gaisano,H.Y., Pessin,J.E.,
            Monnier,P.P., Okamoto,K., Zhang,L. and Sugita,S.
  TITLE     Neuronal SNAP-23 is critical for synaptic plasticity and spatial
            memory independently of NMDA receptor regulation
  JOURNAL   iScience 26 (5), 106664 (2023)
   PUBMED   37168570
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4287)
  AUTHORS   Gentile,G.M., Gamarra,J.R., Engels,N.M., Blue,R.E., Hoerr,I.,
            Wiedner,H.J., Hinkle,E.R., Cote,J.L., Leverence,E., Mills,C.A.,
            Herring,L.E., Tan,X. and Giudice,J.
  TITLE     The synaptosome-associated protein 23 (SNAP23) is necessary for
            proper myogenesis
  JOURNAL   FASEB J 36 (8), e22441 (2022)
   PUBMED   35816155
  REMARK    GeneRIF: The synaptosome-associated protein 23 (SNAP23) is
            necessary for proper myogenesis.
REFERENCE   5  (bases 1 to 4287)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4287)
  AUTHORS   Min,J., Okada,S., Kanzaki,M., Elmendorf,J.S., Coker,K.J.,
            Ceresa,B.P., Syu,L.J., Noda,Y., Saltiel,A.R. and Pessin,J.E.
  TITLE     Synip: a novel insulin-regulated syntaxin 4-binding protein
            mediating GLUT4 translocation in adipocytes
  JOURNAL   Mol Cell 3 (6), 751-760 (1999)
   PUBMED   10394363
  REMARK    Erratum:[Mol Cell 1999 Jul;4(1):following 142]
REFERENCE   7  (bases 1 to 4287)
  AUTHORS   Gerst,J.E.
  TITLE     SNAREs and SNARE regulators in membrane fusion and exocytosis
  JOURNAL   Cell Mol Life Sci 55 (5), 707-734 (1999)
   PUBMED   10379359
  REMARK    Review article
REFERENCE   8  (bases 1 to 4287)
  AUTHORS   Morikawa,Y., Nishida,H., Misawa,K., Nosaka,T., Miyajima,A.,
            Senba,E. and Kitamura,T.
  TITLE     Induction of synaptosomal-associated protein-23 kD (SNAP-23) by
            various cytokines
  JOURNAL   Blood 92 (1), 129-135 (1998)
   PUBMED   9639508
REFERENCE   9  (bases 1 to 4287)
  AUTHORS   Araki,S., Tamori,Y., Kawanishi,M., Shinoda,H., Masugi,J., Mori,H.,
            Niki,T., Okazawa,H., Kubota,T. and Kasuga,M.
  TITLE     Inhibition of the binding of SNAP-23 to syntaxin 4 by Munc18c
  JOURNAL   Biochem Biophys Res Commun 234 (1), 257-262 (1997)
   PUBMED   9168999
REFERENCE   10 (bases 1 to 4287)
  AUTHORS   Wang,G., Witkin,J.W., Hao,G., Bankaitis,V.A., Scherer,P.E. and
            Baldini,G.
  TITLE     Syndet is a novel SNAP-25 related protein expressed in many tissues
  JOURNAL   J Cell Sci 110 (Pt 4), 505-513 (1997)
   PUBMED   9067602
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772299.10.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12282455.1604177.1,
                                           SRR17253014.3797911.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               AL772299.10        57653-57764
            113-209             AL772299.10        74227-74323
            210-365             AL772299.10        84759-84914
            366-510             AL772299.10        86601-86745
            511-4287            AL772299.10        89234-93010
FEATURES             Location/Qualifiers
     source          1..4287
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.37 cM"
     gene            1..4287
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="synaptosomal-associated protein 23"
                     /db_xref="GeneID:20619"
                     /db_xref="MGI:MGI:109356"
     exon            1..112
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            113..209
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..576
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="isoform i is encoded by transcript variant 11;
                     vesicle-membrane fusion protein SNAP-23;
                     synaptosomal-associated protein, 23kD"
                     /codon_start=1
                     /product="synaptosomal-associated protein 23 isoform i"
                     /protein_id="NP_001399562.1"
                     /db_xref="GeneID:20619"
                     /db_xref="MGI:MGI:109356"
                     /translation="MRTKNFESGKNYKATWGDGGDNSPSNVVSKQPSRITNGQPQQTT
                     GAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEK
                     ADTNKNRIDIANTRAKKLIDS"
     exon            210..365
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            366..510
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            511..4287
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1791..1796
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="hexamer: AATAAA"
     polyA_site      1824
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="major polyA site"
     regulatory      2467..2472
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="hexamer: AATAAA"
     polyA_site      2490
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="major polyA site"
     regulatory      4218..4223
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="hexamer: AATAAA"
     polyA_site      4246
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="major polyA site"
     regulatory      4265..4270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="hexamer: ATTAAA"
     polyA_site      4287
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
ORIGIN      
        1 gcaccctgtc cgatcttcta gagtccgaga actgtggagg ctggagagga gtggccggag
       61 ccgccgggtg aggcttctgg aaagtagctg agggaactag tcagcgggac agagtatccg
      121 tatttctgtg cccagcagtg tgacgactca ccatggataa tctgtcccca gaggaagttc
      181 agctgcgggc tcaccaggtt actgatgagg acaaagaact ttgagtctgg aaagaactat
      241 aaggcaacat ggggagatgg tggcgacaac tcacctagca atgtagtatc taagcaaccg
      301 agccggatta caaatggtca gcctcagcaa actacaggag cagccagtgg tggatacatt
      361 aaacgtataa ctaatgatgc cagagaagat gagatggaag agaacctgac tcaagtgggc
      421 agcatcctag gcaacctaaa gaacatggct ctggatatgg gcaatgaaat tgatgctcaa
      481 aaccagcaaa tacagaagat cacagaaaag gctgacacca acaagaatcg tattgacatt
      541 gccaatacaa gagcaaagaa actcattgat agttaaagcc ctgctgtact tctttacctg
      601 ttaactcagt tctctagctc cgctgagtca tttcttattc agagtttgaa aggctgtgag
      661 aaggagcaga ggaggaatgc ctcgctactt tcttactttg tctttagggg gtaggttctt
      721 gctcaggctt ccttacagtc tttctcagtc actctcatag gcttctttcc atacatcacc
      781 gtctcttcat ctcttcattt agcttctttt gcgttcaaga tttggaagca ttgccaaaga
      841 gccatgaaag aagcagctgt ataagtagct tttgtcatta ttggtattgg ttggttggtt
      901 tggttttggt tttgtggtaa agagcaagag gaaggaatag gaaatgaagc tgactcatta
      961 aagaaactac aggtcacaaa aacacagacg agtgcttggg gtgggagctt tcacacatgt
     1021 gttttgttct gcatcactgt ttttcagctt ctgctccaaa ggagaataca atgagttttc
     1081 tagaagtgag cttcacttct gaacccatag tgatttgtac gtatatacat aggttcttgg
     1141 atccagtttc atattgcaca tgcaggaaca ttatataaat gagtgccttt tattctcaca
     1201 caatgagtca tggcatggtc ccattgtagg cctgttaact tcatgaagtt gacggtagcc
     1261 tttaaaagat acacacacac acacacacac acatgaaata ggagatttcc tcaaagtttt
     1321 ggggaaactt ttacagtgta tcatgtgaat tcagatttac ctcaatacta agaattatgt
     1381 ttagatatga aaaaaacttg ttttgatctc aggtagaaaa atagattgct ttgagttttg
     1441 tgtagtttta aacatttaaa aagtcataat ttgttactaa aagttgtttg gaaaattatg
     1501 cctttatatt aattattgat gaccgcactg ccattctctc tgccttatgc acagaatcaa
     1561 gtttatgtag atcctgaagt gttagggaag ctgaaatggt atttgtcaca tttgtttaaa
     1621 aattagcatc tgtacacttt agagctacta aagtagactg gtttcaccaa taaccattgc
     1681 tttattctta caattaaatt ttataattaa tgatattgtt ctttcaaata ggtaatgttt
     1741 ctatgactta tttgtggggg caatcatttt atcagcttct gttgacatta aataaagcaa
     1801 atgtccatac atcaagcact ccaatagaaa gctgtattag ctctcttcta atttttagca
     1861 gaagtgttta caggagtttc tatggtttgc tatgagtcca ttctagacat tatcttagtc
     1921 atttgtactt aaatacacta ctgagtattt ctgagtgaga attacaagtc acttattgaa
     1981 gaagataaat gtagcctacc aacattcaga gggtgaagag gacagtattt aaaacaacag
     2041 agaaatgcct ggcatggtgg cgcacacctt taatcccagc actcgggagg cagaggcagg
     2101 cagatttctg agttcgaggc cagcctggtc tacagagtga gttccagttc agccagggct
     2161 atacagagaa accctgtctc gaaaaacaaa caaaaaaatc aaagaagcac tccatgtcag
     2221 agtggttcat ttgtcaggta aagatactga atttaagagg tgtggctaag tccaaaacac
     2281 tgaattgtgc tgtacctaaa agtgctttcc ttaaaaacat gctgatttgt ctaaaggaac
     2341 ggtaccaaaa ggtggcatcc aaggtatatt tggttagaat atgcaccaaa acccctttgc
     2401 tcttgctggc tggtgtgaat gtatgctatt tctttgtctt ggtttccata tctgtaaatg
     2461 gggattaata aatcttattt tataaactta ttcacagacc agtaatgccc agaaatttct
     2521 tagaatatgc caggctcaga gtccatactg gtaatcccaa aatttgggaa cctgaggcac
     2581 aatctaccca gtgagttgtg ggccagccta aattgtgtca aaaaacagca ccccctcccc
     2641 ccaaaaaaag aatcaaccaa caaaactctt agaacagtgc ctataagatg taactgtcat
     2701 aaatgatagc tattttctct agactggagg aagctctttt tggtcaaaga tcttaggttt
     2761 ccccttctcc agagaaaaag caaagaagca gataccaagt gcctttgcct gctgaaccat
     2821 catgcgcacc acttccatta tttttgagat acgatagcaa gtaaatacaa gctggagatt
     2881 tatttttggt ctgttttcta gtatagtgat cttgaataca atacctgatt acagataaga
     2941 gctagtatct tgtaccaaac tttttgtttg ttgttttcgt ttgtttttct tgacacaggg
     3001 tttctctgtg tagccttggc tgtcctagaa atcactgtgt agaccaggct ggcctcaaac
     3061 tcagagatct acctgcctct gcctcccatg tgctgggatt aaaggtgtgt gccaccacca
     3121 cctggcaact ttttattttt ttaaactggg tctcaccatg taaagctggc tgacctcaaa
     3181 cccagagatc taccagtcgc tactccgcag atactgaaat caagtgtgcc actacaccca
     3241 acttcaaaat tttacgtttt aaaaaatttt aaagcccaaa tttcatctta acttatacgg
     3301 ctgtacctat ttcatccctt cttcagtttt aatgtattct ttggtcaatt cttttttctt
     3361 tcttttttat ttttcttttt tcttttttgg tttttcgaga cagggtttct ctgtacagcc
     3421 ttggctgtcc tggaactcac tctgtagacc aagctggcct tgaactcaga aatccgccgg
     3481 cctctgcctc ccaagtgtta ggattaaagg tgtgtgccac cactgcccgg ccttttatta
     3541 ttattattat tattattatt attattagta gtagtagtag tagtagtagt agtagtagta
     3601 cactgaaact gtcttcagac acatcagaag agggcgtcag atctcattaa gggtggttgt
     3661 gagccaccat atggttgctg ggatttgaac tcaggacctt cagaagagca gccagtgctc
     3721 ttaacctctg agccatctct ccagccctct tcagtcaatt cttaatcttt ccttatcaca
     3781 tatggattct gactcttcta ttaagttaaa catcttatta tgagcatata aagttaagtt
     3841 tctaggactg gggatgtaga accgctcagt tcatgaagtg cttgcctagt attcaaaaac
     3901 tggattcagc tctggactac cgtgtaagcc aggtgtggtg gttgccctcc aaacgcagcc
     3961 ctgggtagga ggatcagggg ctcaaggtca tcctcaggct cagttccagg acaacctgga
     4021 atatgtgaaa caccacccaa aaaccaaaat ggccaataat atggcttagc aggtaaggct
     4081 ggcaacccaa gtttgaactc ctccgggacc taaatggtag aagaagcaag ccaactccta
     4141 aaagtattct tctgacttcc acatgtgctg tagtggatgc aagcttgtgt acacatatac
     4201 ataaaaaatg taatgaaaat aaaaagcaaa agctatttga atgccatttt cctggatgct
     4261 cttaattaaa attccaagtt atcctaa
//
