LOCUS       NM_001412628             943 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus synaptosomal-associated protein 23 (Snap23),
            transcript variant 6, mRNA.
ACCESSION   NM_001412628
VERSION     NM_001412628.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 943)
  AUTHORS   Huang,M., Chow,C.H., Gurdita,A., Harada,H., Pham Truong,V.Q.B.,
            Eide,S., Sun,H.S., Feng,Z.P., Monnier,P.P., Wallace,V.A. and
            Sugita,S.
  TITLE     SNAP-25, but not SNAP-23, is essential for photoreceptor
            development, survival, and function in mice
  JOURNAL   Commun Biol 7 (1), 34 (2024)
   PUBMED   38182732
  REMARK    GeneRIF: SNAP-25, but not SNAP-23, is essential for photoreceptor
            development, survival, and function in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 943)
  AUTHORS   Huang,M., Bin,N.R., Rai,J., Ma,K., Chow,C.H., Eide,S., Harada,H.,
            Xiao,J., Feng,D., Sun,H.S., Feng,Z.P., Gaisano,H.Y., Pessin,J.E.,
            Monnier,P.P., Okamoto,K., Zhang,L. and Sugita,S.
  TITLE     Neuronal SNAP-23 is critical for synaptic plasticity and spatial
            memory independently of NMDA receptor regulation
  JOURNAL   iScience 26 (5), 106664 (2023)
   PUBMED   37168570
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 943)
  AUTHORS   Gentile,G.M., Gamarra,J.R., Engels,N.M., Blue,R.E., Hoerr,I.,
            Wiedner,H.J., Hinkle,E.R., Cote,J.L., Leverence,E., Mills,C.A.,
            Herring,L.E., Tan,X. and Giudice,J.
  TITLE     The synaptosome-associated protein 23 (SNAP23) is necessary for
            proper myogenesis
  JOURNAL   FASEB J 36 (8), e22441 (2022)
   PUBMED   35816155
  REMARK    GeneRIF: The synaptosome-associated protein 23 (SNAP23) is
            necessary for proper myogenesis.
REFERENCE   5  (bases 1 to 943)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 943)
  AUTHORS   Min,J., Okada,S., Kanzaki,M., Elmendorf,J.S., Coker,K.J.,
            Ceresa,B.P., Syu,L.J., Noda,Y., Saltiel,A.R. and Pessin,J.E.
  TITLE     Synip: a novel insulin-regulated syntaxin 4-binding protein
            mediating GLUT4 translocation in adipocytes
  JOURNAL   Mol Cell 3 (6), 751-760 (1999)
   PUBMED   10394363
  REMARK    Erratum:[Mol Cell 1999 Jul;4(1):following 142]
REFERENCE   7  (bases 1 to 943)
  AUTHORS   Gerst,J.E.
  TITLE     SNAREs and SNARE regulators in membrane fusion and exocytosis
  JOURNAL   Cell Mol Life Sci 55 (5), 707-734 (1999)
   PUBMED   10379359
  REMARK    Review article
REFERENCE   8  (bases 1 to 943)
  AUTHORS   Morikawa,Y., Nishida,H., Misawa,K., Nosaka,T., Miyajima,A.,
            Senba,E. and Kitamura,T.
  TITLE     Induction of synaptosomal-associated protein-23 kD (SNAP-23) by
            various cytokines
  JOURNAL   Blood 92 (1), 129-135 (1998)
   PUBMED   9639508
REFERENCE   9  (bases 1 to 943)
  AUTHORS   Araki,S., Tamori,Y., Kawanishi,M., Shinoda,H., Masugi,J., Mori,H.,
            Niki,T., Okazawa,H., Kubota,T. and Kasuga,M.
  TITLE     Inhibition of the binding of SNAP-23 to syntaxin 4 by Munc18c
  JOURNAL   Biochem Biophys Res Commun 234 (1), 257-262 (1997)
   PUBMED   9168999
REFERENCE   10 (bases 1 to 943)
  AUTHORS   Wang,G., Witkin,J.W., Hao,G., Bankaitis,V.A., Scherer,P.E. and
            Baldini,G.
  TITLE     Syndet is a novel SNAP-25 related protein expressed in many tissues
  JOURNAL   J Cell Sci 110 (Pt 4), 505-513 (1997)
   PUBMED   9067602
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772299.10.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13862051.787699.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                AL772299.10        57653-57719
            68-164              AL772299.10        74227-74323
            165-206             AL772299.10        75109-75150
            207-255             AL772299.10        75514-75562
            256-373             AL772299.10        76117-76234
            374-529             AL772299.10        84759-84914
            530-674             AL772299.10        86601-86745
            675-943             AL772299.10        96038-96306
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.37 cM"
     gene            1..943
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="synaptosomal-associated protein 23"
                     /db_xref="GeneID:20619"
                     /db_xref="MGI:MGI:109356"
     exon            1..67
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            68..164
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..749
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="isoform d is encoded by transcript variant 6;
                     vesicle-membrane fusion protein SNAP-23;
                     synaptosomal-associated protein, 23kD"
                     /codon_start=1
                     /product="synaptosomal-associated protein 23 isoform d"
                     /protein_id="NP_001399557.1"
                     /db_xref="GeneID:20619"
                     /db_xref="MGI:MGI:109356"
                     /translation="MDNLSPEEVQLRAHQVTDESLESTRRILGLAIESQDAGIKTITM
                     LDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCICPCNRTKNFESGKNYKAT
                     WGDGGDNSPSNVVSKQPSRITNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGS
                     ILGNLKNMALDMGNEIDAQNQQIQKITEKPEDLEARTAGYLHRELRDLSTTKQ"
     exon            165..206
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            207..255
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            256..373
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            374..529
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            530..674
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     exon            675..943
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /inference="alignment:Splign:2.1.0"
     regulatory      924..929
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="hexamer: AATAAA"
     polyA_site      943
                     /gene="Snap23"
                     /gene_synonym="23kDa; SNAP-23; Sndt; Syndet"
                     /note="major polyA site"
ORIGIN      
        1 gcaccctgtc cgatcttcta gagtccgaga actgtggagg ctggagagga gtggccggag
       61 ccgccggagt atccgtattt ctgtgcccag cagtgtgacg actcaccatg gataatctgt
      121 ccccagagga agttcagctg cgggctcacc aggttactga tgagtctctg gaaagcacaa
      181 ggagaatcct gggtttagcc attgagtctc aggatgcagg aatcaagacc atcactatgc
      241 tggatgagca aggggaacaa ctaaatcgca tagaagaagg catggaccaa ataaataaag
      301 acatgagaga ggcagagaag actttaacag aactcaacaa gtgttgtggc ctctgcatct
      361 gcccttgtaa taggacaaag aactttgagt ctggaaagaa ctataaggca acatggggag
      421 atggtggcga caactcacct agcaatgtag tatctaagca accgagccgg attacaaatg
      481 gtcagcctca gcaaactaca ggagcagcca gtggtggata cattaaacgt ataactaatg
      541 atgccagaga agatgagatg gaagagaacc tgactcaagt gggcagcatc ctaggcaacc
      601 taaagaacat ggctctggat atgggcaatg aaattgatgc tcaaaaccag caaatacaga
      661 agatcacaga aaagccggag gaccttgagg cgaggacagc aggatatctt cacagagagc
      721 tgagagatct gtcaacaacc aaacagtaag aggacagaga gcataatggc cacgttacta
      781 cactgaaaca gctcttgact gtgtcctagt ttttctttta ccgcctccgt tttctcacta
      841 cctactcgca cagaagcctg taacatacct tctgttactc ctccacttcc aaattatttg
      901 aaggttacca gtagcttttc agaaataaaa accaataata aaa
//
