LOCUS       NM_027188               6878 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus SET and MYND domain containing 3 (Smyd3), mRNA.
ACCESSION   NM_027188
VERSION     NM_027188.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6878)
  AUTHORS   Sajic,T., Ferreira Gomes,C.K., Gasser,M., Caputo,T., Bararpour,N.,
            Landaluce-Iturriria,E., Augsburger,M., Walter,N., Hainard,A.,
            Lopez-Mejia,I.C., Fracasso,T., Thomas,A. and Gilardi,F.
  TITLE     SMYD3: a new regulator of adipocyte precursor proliferation at the
            early steps of differentiation
  JOURNAL   Int J Obes (Lond) 48 (4), 557-566 (2024)
   PUBMED   38148333
  REMARK    GeneRIF: SMYD3: a new regulator of adipocyte precursor
            proliferation at the early steps of differentiation.
REFERENCE   2  (bases 1 to 6878)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6878)
  AUTHORS   Williams,J.B., Cao,Q., Wang,W., Lee,Y.H., Qin,L., Zhong,P., Ren,Y.,
            Ma,K. and Yan,Z.
  TITLE     Inhibition of histone methyltransferase Smyd3 rescues NMDAR and
            cognitive deficits in a tauopathy mouse model
  JOURNAL   Nat Commun 14 (1), 91 (2023)
   PUBMED   36609445
  REMARK    GeneRIF: Inhibition of histone methyltransferase Smyd3 rescues
            NMDAR and cognitive deficits in a tauopathy mouse model.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6878)
  AUTHORS   Lukinovic,V., Hausmann,S., Roth,G.S., Oyeniran,C., Ahmad,T.,
            Tsao,N., Brickner,J.R., Casanova,A.G., Chuffart,F., Benitez,A.M.,
            Vayr,J., Rodell,R., Tardif,M., Jansen,P.W.T.C., Coute,Y.,
            Vermeulen,M., Hainaut,P., Mazur,P.K., Mosammaparast,N. and
            Reynoird,N.
  TITLE     SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation
            Damage through RNF113A Methylation-Phosphorylation Cross-talk
  JOURNAL   Cancer Discov 12 (9), 2158-2179 (2022)
   PUBMED   35819319
REFERENCE   5  (bases 1 to 6878)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6878)
  AUTHORS   Diehl,F., Brown,M.A., van Amerongen,M.J., Novoyatleva,T.,
            Wietelmann,A., Harriss,J., Ferrazzi,F., Bottger,T., Harvey,R.P.,
            Tucker,P.W. and Engel,F.B.
  TITLE     Cardiac deletion of Smyd2 is dispensable for mouse heart
            development
  JOURNAL   PLoS One 5 (3), e9748 (2010)
   PUBMED   20305823
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6878)
  AUTHORS   Brown,M.A., Sims,R.J. 3rd, Gottlieb,P.D. and Tucker,P.W.
  TITLE     Identification and characterization of Smyd2: a split SET/MYND
            domain-containing histone H3 lysine 36-specific methyltransferase
            that interacts with the Sin3 histone deacetylase complex
  JOURNAL   Mol Cancer 5, 26 (2006)
   PUBMED   16805913
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 6878)
  AUTHORS   Hamamoto,R., Furukawa,Y., Morita,M., Iimura,Y., Silva,F.P., Li,M.,
            Yagyu,R. and Nakamura,Y.
  TITLE     SMYD3 encodes a histone methyltransferase involved in the
            proliferation of cancer cells
  JOURNAL   Nat Cell Biol 6 (8), 731-740 (2004)
   PUBMED   15235609
  REMARK    GeneRIF: SMYD3 encodes a histone methyltransferase involved in the
            proliferation of cancer cells.
REFERENCE   9  (bases 1 to 6878)
  AUTHORS   Marikawa,Y., Fujita,T.C. and Alarcon,V.B.
  TITLE     An enhancer-trap LacZ transgene reveals a distinct expression
            pattern of Kinesin family 26B in mouse embryos
  JOURNAL   Dev Genes Evol 214 (2), 64-71 (2004)
   PUBMED   14727108
REFERENCE   10 (bases 1 to 6878)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130279.5, AC120870.8, AC138225.11 and AC117756.8.
            
            On Sep 28, 2017 this sequence version replaced NM_027188.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052431.1, AK010447.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-254               AC130279.5         130264-130517       c
            255-318             AC130279.5         35831-35894         c
            319-426             AC130279.5         24154-24261         c
            427-484             AC130279.5         22883-22940         c
            485-621             AC120870.8         3895-4031
            622-689             AC138225.11        172964-173031       c
            690-792             AC138225.11        171495-171597       c
            793-903             AC138225.11        164953-165063       c
            904-991             AC117756.8         172998-173085       c
            992-1166            AC117756.8         166444-166618       c
            1167-1275           AC117756.8         94895-95003         c
            1276-6878           AC117756.8         74667-80269         c
FEATURES             Location/Qualifiers
     source          1..6878
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 83.48 cM"
     gene            1..6878
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /note="SET and MYND domain containing 3"
                     /db_xref="GeneID:69726"
                     /db_xref="MGI:MGI:1916976"
     exon            1..254
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            255..318
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            319..426
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            427..484
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            485..621
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            622..689
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            690..792
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            793..903
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            904..991
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1166
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1275
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..6878
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1563..1568
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /note="hexamer: ATTAAA"
     polyA_site      1583
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /note="major polyA site"
     regulatory      1997..2002
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /note="hexamer: AATACA"
     polyA_site      2032
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
     regulatory      2759..2764
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /note="hexamer: AATACA"
     polyA_site      2776
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
     polyA_site      3688
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
     regulatory      4460..4465
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /note="hexamer: AATAAA"
     polyA_site      4479
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
     regulatory      6859..6864
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
                     /note="hexamer: AATAAA"
     polyA_site      6878
                     /gene="Smyd3"
                     /gene_synonym="2410008A19Rik; Zmynd1"
ORIGIN      
        1 cgcaagcgca ggacgcaggc gcgcagtcag aaaacacgag actcaagctg agggacgcag
       61 ttcggatctg aggtgtggat ctgaggaagg atggaggcac tgaaggtgga aaagttcacg
      121 actgccaacc ggggaaacgg gctgcgtgct gtggctccac tgcgccccgg ggagctgctc
      181 ttccgctccg accccttggc ttacactgtg tgcaagggga gtcgtggcgt agtctgtgat
      241 cgctgcctac tggggaagga gaagctgatg cgttgttctc aatgccgaat tgccaaatac
      301 tgcagtgcca agtgtcagaa aaaagcctgg ccggaccaca gacgggaatg cagttgtctt
      361 aaaagctgca agcccagata tccgcccgac tccgtgagac ttctgggcag ggttatcgtc
      421 aagctgatgg atgaaaagcc ctcagagtca gagaaacttt attcatttta tgatctggag
      481 tccaatatta gcaaactcac tgaagataag aaagagggcc tgaggcaact tgcaatgact
      541 tttcaacatt tcatgagaga ggagatccag gatgcgtctc agctgccgcc ttcttttgac
      601 ctttttgaag cctttgcaaa agtgatctgc aattcgttca ctatctgcaa cgcggagatg
      661 caggaggtcg gcgttggcct gtaccccagt atgtctttgc tgaatcacag ctgtgacccc
      721 aactgctcca tcgtattcaa cgggccccac ctcttactgc gtgcagtgcg ggaaattgaa
      781 gcaggagagg agctcaccat ctgctacctg gacatgctga tgaccagcga ggaacgccgg
      841 aagcagctga gggaccagta ctgctttgag tgtgactgca tccgatgcca aacccaggac
      901 aaggatgctg acatgctaac gggtgacgag caaatatgga aggaggttca agagtcgctg
      961 aagaaaatcg aagagctgaa ggcgcactgg aagtgggagc aggttctggc gctgtgccag
     1021 gcgatcataa acagcaattc caaccggctt cccgacatca acatctacca gctgaaggtg
     1081 ctcgactgtg ccatggatgc ctgcatcaac ctggggatgc tggaggaggc gttgttctac
     1141 gccatgcgca ccatggagcc gtaccggatt tttttccctg gaagccatcc cgtcagaggt
     1201 gtgcaagtga tgaaagttgg caagctgcag ctccatcaag gcatgtttcc tcaagccatg
     1261 aagaacctga ggctggcctt tgacattatg aaagtgaccc acggccgaga gcacagcctg
     1321 attgaagatt tgattcttct cctggaagaa tgtgatgcca acatacgagc ctcctaagga
     1381 cccccagaag gacggggaag gtggcgcgcc ctccatcgaa cgccttactg aggtcacacg
     1441 ctctgtggtg tttgctgtgt ggaccttctg tagaaattgc caatgtgttt atgtgggtaa
     1501 atgtgattct gtggcatgtc gtgagaagtc ttactcgtga tagagcagaa ccattacaat
     1561 aaattaaaaa gacgagtcca aaatgccact ggcgacttgg ctttgcctat tctcaggtgg
     1621 ttttgatggt taagatgtca acattggaag caggagcttt ccaaaagaag aatggaatcc
     1681 caggcagccc ctgaaaggca gaggcaggtg gatctccatg agttcgaggc cagttttgtc
     1741 tacacagtga attacaagac agccatagcc ttgtagagag accctgttcc agaaactgaa
     1801 aaaaaatagg gtagaatatg ttcaagtttc ctctgtgtgt gtgtgtatat agaagtaaac
     1861 ggataaaagt aataattttc acatagactt ctaaacacaa gtgtatatca agaagatttt
     1921 ttattgtact tttatcttta ttgagatgtc ttaattgtac ttattaacat ggttcactgt
     1981 gatatttcta tatctgaata cacacacatg gcgcccagtt gtcactgagg aactctggcc
     2041 tccatttatt ttcctgcctc catggatcac cgtttctctc tctctctctc tctctctctc
     2101 tctctctctc tctctctctc tcacacacac acacacacac acacacacac acaccctcct
     2161 gactcttaca catgagaggg aaaacgcagt acttgtctct gtcgtccccc cttatttctc
     2221 tttgtataat ttcctccagt tctgtccatt cggctgcagc tgacagagct tcactcttct
     2281 ttatggctga gtaatagcct gttatttgta tgtacttggt aaatgttagc aagcacctac
     2341 agtaactgca gccttggcga ttatgaatgg ctttatagta gacatgtcag gcaagtatgt
     2401 ttggggttta atttcccttt gacatacacc tagaagtggc atggctgggt cccatggtgg
     2461 tactctttta acttcttaga tgaacctcct ccatactctc cttggcttta ggttcccatc
     2521 aacagtgtat gagagttcct gttctccatg ttcacgtcag catttgttat gggttttttt
     2581 ttccttgctt tgctgttggc tttaatcgca ttttaactgg cgtacatgat atttcatcat
     2641 agtttcgatt tccctgatga ccaatggtat tgattgtgcc tcatgttttt gtgactgttc
     2701 agaacagttg ttcattttgt aatcagattc ttgccttttc aattccttac ctattataaa
     2761 tacactatgt attgtggata tgactccttc actgggagga tggttggcag acagttctct
     2821 agttctgtag attgtctttt cctctgctgt tttgtgtgct gtacagaacc tcagtgtaat
     2881 tgtttgtctt cggttctgat cccctccctt ctataatcac ataaagccat tgcttattct
     2941 ggcttctatg atactccatt gcccttactg acgtgttccc atgcatgttc ccagcttgat
     3001 cttgcatttg gtctttggtc catcgtgagc tgagatccgt ccgtcgtgaa aaggttcggt
     3061 ttccttctct tgcatgtggc tgtctgcctt ccctgcacac tttgttgaag agggagtcac
     3121 acagccttta tggtttgggc acgtttgtca agaaggagcg ggttctaggt ttgtgggctt
     3181 acttttgggc tctccgttca gtcccatggg tcccttgctc tatggccatg ccgtttctgc
     3241 tagcacggct ctgtaatatg gcttgcagtc aggtgccatg ttgcctctgg cctcactggt
     3301 ttcactcaag atgattttgt ctgtcctgag tctgttgtga agaagcagaa ttctgaaacg
     3361 ttgcctttac tcctctgcag tgaataacta cgtgttattt cctcctgaat acccctccaa
     3421 cacaggaatc atcatctcaa atcctaggtc taggccattt ccaacattac taggaaaaca
     3481 ctgtaaggct cacacaaaaa gaacaagata ctgaagtcaa ctctttgtat aaatctttgc
     3541 tgtactttat aattctttgt gtgtgttaaa actttcttaa ccccctttct tctgtaattg
     3601 ctctagtctg tgctttgctg tgctggtggg cagagcacaa agctctattg ccctgtggta
     3661 aactgtgttc tcatcctcat tcaccttagc ctggtttcct ctgcttttgt tgtcttttcc
     3721 acttccccaa ccccttggcc tgcttctcta tctttctgct ttagaaaaat aacaaaaata
     3781 tttcccttgt ccaaaaaaaa aaaaaaagtt gaaccttgta tggctcactg gtcctggaag
     3841 cagtgcggtc cttcctgttc cagtgagatt ctagtagtaa atcagaccgg tgggctgctt
     3901 cagatgaaat ggcccttaga tagtaggcta caatccactc ctctgttaca gggatacagg
     3961 gtgtgaaggc agactccaaa atagtggcct ccaagggagg gaggcagaag acactgtcag
     4021 aatgacacat ggtcgtcaga gcctgaaggg gtatacctta agttagagca aagaaagctg
     4081 acagcaagaa gctggggccc accggccgaa catctggtgc catggaaacg atgacatgtg
     4141 tagggtgtct gatgcacacc cctgagctcc aggacctttt cctaaggatg cttctgctca
     4201 tgcccagctg tcatccagcc agcacacccc taggcagtgc tgtctctgct agccacagta
     4261 gcttatagtg ggcatctgaa ggccgtttca caatgaggaa agaagtctga cgtcaggtgc
     4321 actagaaccc caccccagat ttgctaagta actctgagag gaccttgacc tcagcctttt
     4381 gaaaggccag ttctatccaa ttcaacagat atctattaaa tgattctgat gttttcagga
     4441 aacgtgcaca caaaggccaa ataaaacttg catgacctac caagtgtata ctgagagaac
     4501 ttgcatccat tagcttatgc tgtatgacaa acagccccag aacataactt ggtttagctc
     4561 atagtgctgt aggtcagcac tttgagctgg acatttctgg tttgttccgg gacttattgg
     4621 ttgtgaatcg ttgctgttat tggtaggtca cttgcagaat cagagtgact aaatgataca
     4681 gcaccttaag ttggctaacc agttatgtcc acaggccagg agagttccag gatcagtaag
     4741 tcaatcaact cccagccaac cagtgctttt caagcctgct tctatcacat tggctttagt
     4801 ccgataggtc aatgcccacc ccaaggcatg gatatgtgtt cccatctctg tagaaacagc
     4861 tacagtccct cagcaggggc atagccacag gagtggggaa tggtgccatc tgggcccttc
     4921 accatagcag ccctgaaact atctatatgc tatggaacac ttaacaaata tgatgaaata
     4981 tacactctgt acttccggta atagactaga ataatttgcc attctaatcc agattcttag
     5041 aacactccag ggcccatcgg tgaattctct gacattctca tcaaatgaaa aacaaacttc
     5101 ctacattctg gaaagatggg ggtgggggat ggaaccaaga gatgaggacc aagagaaagc
     5161 tgtattgttt gtcccccttt aactcactgg ggaaatgaaa gaccccaaga gaaagtcagg
     5221 gagtaacttc catggcccat gggcagagtt cgtagatagg atgccgtgct tgccagcttt
     5281 ctgaatgaaa tttatcagtc actgatgatc ctggattaag agatttgtct tcacgcctcc
     5341 tagagaaaat ctgatgggct ttgaaatccc tctctgccaa cttacagtgt gtgaggatga
     5401 aggcaccctg cgtggaccca gttttaatac aaagcaaaca tttaagcaaa ggtaaatatt
     5461 tacccaataa aattacagca aaataatttt ggcaaagagg gaaacggtca gagaacacaa
     5521 tttaaaatcc gtgtcgccag tgactgagga ttgattgcgg ccccagcctc tacgaagcct
     5581 tcccattaat ccatggtcat tgtagcggca ggcttttctc acgtcagtaa cttgacgcca
     5641 ttagccgctc ctctgggatg agaacacatt tgaactgaaa atgaacacgc cgggcataat
     5701 ttatagccgt gccacatgaa tgccaagagt gtgaggagga agctgcttgg gaatccactc
     5761 atggtggcta cccagacctg acttcctcta agcaagagcc agacggctgc aaaccacagg
     5821 cccccagtta gacttggctg cagggaggga gggaaattgc atacaggagc cagatgtctt
     5881 gaaaattccc tcctagtcca gccagtcagg agtggaggca aggctcccat agcagagccc
     5941 accggggttc atcagagaga gggttctgga ccttgtgaaa accgtgaaat cttcatgtca
     6001 agcagtcacg gaaggaagcc cctttcctct gaggtctgat gggagaacac ccgaatccaa
     6061 gccagaagcc tccctaagac tgggatcaga gtgaggatgc tctcggcgtg ttcaccacta
     6121 atccaaagct ctgaaagagc agccgaagca tctctcctgc ccctacattt actattcaaa
     6181 tttgctttca attggcatag aaagtgtgcc cctgcctatg gacctaacct gctattccag
     6241 agggaccagc ttcccagtcc caggcctcag cctttgtcag ggccgtgtgt gtgtgtgtgt
     6301 gtgtgtgtgt gtgtgagtgc atgcatacaa ggatgttgct gtaggatatg agagggggaa
     6361 atggaggttt gagggactgc agagagaacc taatagcata catgtgacat gaaagtgaaa
     6421 aggagagagg gggattgacc cacatatgta taaagtacat acaaatatac cacagtgaaa
     6481 cctgctacac acacacacac acacacacac atacacacac acaaattaag gacatacaaa
     6541 aataccacag tgaagcctgc tttctatgcc aagtgaaaac aaatgttaac agtcagtgta
     6601 ggggtgggag agatggttca gcagttaaga gcactggctg ctctttcaga ggtcccaact
     6661 tcaatcccca gcacttagaa cggcagctca caatcgtctg caactccagt tccaggagat
     6721 acgatgccct ctgatgccct cttctgacca tcaagggttc caggcactca cgtggtgcac
     6781 agacataaca tgcaggcaga tgcttacaca gataaaataa tttttaaaat taactgtttt
     6841 cttttcaagt gaatgtagaa taaaaactgt aaggtgca
//
