LOCUS       NM_011422                649 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus submaxillary gland androgen regulated protein 3A
            (Smr3a), mRNA.
ACCESSION   NM_011422 XM_904494
VERSION     NM_011422.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Fu,S., Tar,M.T., Melman,A. and Davies,K.P.
  TITLE     Opiorphin is a master regulator of the hypoxic response in corporal
            smooth muscle cells
  JOURNAL   FASEB J 28 (8), 3633-3644 (2014)
   PUBMED   24803544
  REMARK    GeneRIF: In corporal smooth muscle cells from a sickle-cell-disese
            mouse, there was Smr3a up-regulation at a life stage prior to
            priapism, so the changes in gene expression are unlikely due to
            priapism, but rather due to the hypoxic conditions in SCD.
REFERENCE   2  (bases 1 to 649)
  AUTHORS   Erdreich-Epstein,A., Ganguly,A.K., Shi,X.H., Zimonjic,D.B. and
            Shackleford,G.M.
  TITLE     Androgen inducibility of Fgf8 in Shionogi carcinoma 115 cells
            correlates with an adjacent t(5;19) translocation
  JOURNAL   Genes Chromosomes Cancer 45 (2), 169-181 (2006)
   PUBMED   16252261
REFERENCE   3  (bases 1 to 649)
  AUTHORS   Tronik-Le Roux,D., Senorale-Pose,M. and Rougeon,F.
  TITLE     Three novel SMR1-related cDNAs characterized in the submaxillary
            gland of mice show extensive evolutionary divergence in the protein
            coding region
  JOURNAL   Gene 142 (2), 175-182 (1994)
   PUBMED   8194749
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154123.10.
            
            On Jul 7, 2022 this sequence version replaced NM_011422.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034553.1, BG868670.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-76                AC154123.10        86252-86327         c
            77-143              AC154123.10        84084-84150         c
            144-649             AC154123.10        80332-80837         c
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.56 cM"
     gene            1..649
                     /gene="Smr3a"
                     /gene_synonym="MSG1; MSG3; Smr1; Smr3"
                     /note="submaxillary gland androgen regulated protein 3A"
                     /db_xref="GeneID:20599"
                     /db_xref="MGI:MGI:102763"
     exon            1..76
                     /gene="Smr3a"
                     /gene_synonym="MSG1; MSG3; Smr1; Smr3"
                     /inference="alignment:Splign:2.1.0"
     exon            77..143
                     /gene="Smr3a"
                     /gene_synonym="MSG1; MSG3; Smr1; Smr3"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..533
                     /gene="Smr3a"
                     /gene_synonym="MSG1; MSG3; Smr1; Smr3"
                     /note="salivary protein MSG1; submaxillary gland
                     androgen-regulated protein 1; submaxillary gland androgen
                     regulated protein 3"
                     /codon_start=1
                     /product="submaxillary gland androgen-regulated protein 3A
                     precursor"
                     /protein_id="NP_035552.1"
                     /db_xref="CCDS:CCDS19398.1"
                     /db_xref="GeneID:20599"
                     /db_xref="MGI:MGI:102763"
                     /translation="MKPLNLVLGLCILVGCFLSCECHRGPRRHDPRGPFPPPPPPHGP
                     GIGRPHPPPFGPGIGRPPPPPFGPGIGRPPPPPPCPPVPPHPRPPSNPSPPPTPSIPP
                     TGPPTTVQATTMPAASISITTPTARDSTDIFWRLWELINSLLQQE"
     exon            144..649
                     /gene="Smr3a"
                     /gene_synonym="MSG1; MSG3; Smr1; Smr3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      621..626
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smr3a"
                     /gene_synonym="MSG1; MSG3; Smr1; Smr3"
                     /note="hexamer: AATAAA"
     polyA_site      649
                     /gene="Smr3a"
                     /gene_synonym="MSG1; MSG3; Smr1; Smr3"
                     /note="major polyA site"
ORIGIN      
        1 agtcttccac ccctcaaaaa taactgacca gaccgcttct gaccagcaca ttcaccagct
       61 aagaagtgtc tccaagaggc tgaaaaaaga tgaagccact caatttggtc ttaggcctct
      121 gcattcttgt aggatgcttc ctgtcctgtg agtgtcacag aggccctaga agacatgatc
      181 ctagaggacc attccctcct cctccccctc cccatggtcc aggaattggt agaccacacc
      241 ctccaccctt tggtccagga attggtagac caccccctcc accctttggt ccaggaattg
      301 gtcgaccacc ccctccacct ccttgtccac cagttcctcc acatcctaga cctccaagca
      361 atccgtctcc tccacctact ccaagcattc ctcctaccgg acctcctacc acagtacaag
      421 caactacaat gccagctgcc agtatctcca taactactcc tactgctaga gattccactg
      481 atattttttg gaggttgtgg gaattaataa attccctttt gcagcaagaa taaaatcaac
      541 caaagcactg tggaattttg ggagaaataa cctttaaagg cttaagaaac agtctttacc
      601 taagcattat tcaaaatgaa aataaagagc tgagcagcat tataaagca
//
