LOCUS       NM_022315               2832 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus SPARC related modular calcium binding 2 (Smoc2), mRNA.
ACCESSION   NM_022315
VERSION     NM_022315.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2832)
  AUTHORS   Coren,L., Zaffryar-Eilot,S., Odeh,A., Kaganovsky,A. and Hasson,P.
  TITLE     Fibroblast diversification is an embryonic process dependent on
            muscle contraction
  JOURNAL   Cell Rep 43 (12), 115034 (2024)
   PUBMED   39636726
REFERENCE   2  (bases 1 to 2832)
  AUTHORS   Zhu,Z., Zou,Q., Wang,C., Li,D., Yang,Y., Xiao,Y., Jin,Y., Yan,J.,
            Luo,L., Sun,Y. and Liang,X.
  TITLE     Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors
            and is Required for Placenta Morphogenesis and Vasculature
            Formation
  JOURNAL   Adv Sci (Weinh) 11 (32), e2400238 (2024)
   PUBMED   38923264
REFERENCE   3  (bases 1 to 2832)
  AUTHORS   Li,H., Tang,Q., Yang,T., Wang,Z., Li,D., Wang,L., Li,L., Chen,Y.,
            Huang,H., Zhang,Y. and Chen,Y.
  TITLE     Segregation of morphogenetic regulatory function of Shox2 from its
            cell fate guardian role in sinoatrial node development
  JOURNAL   Commun Biol 7 (1), 385 (2024)
   PUBMED   38553636
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2832)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 2832)
  AUTHORS   Weiss,A.C., Blank,E., Bohnenpoll,T., Kleppa,M.J., Rivera-Reyes,R.,
            Taketo,M.M., Trowe,M.O. and Kispert,A.
  TITLE     Permissive ureter specification by TBX18-mediated repression of
            metanephric gene expression
  JOURNAL   Development 150 (6) (2023)
   PUBMED   36960826
REFERENCE   6  (bases 1 to 2832)
  AUTHORS   Mager,J., Schultz,R.M., Brunk,B.P. and Bartolomei,M.S.
  TITLE     Identification of candidate maternal-effect genes through
            comparison of multiple microarray data sets
  JOURNAL   Mamm Genome 17 (9), 941-949 (2006)
   PUBMED   16964442
REFERENCE   7  (bases 1 to 2832)
  AUTHORS   Rocnik,E.F., Liu,P., Sato,K., Walsh,K. and Vaziri,C.
  TITLE     The novel SPARC family member SMOC-2 potentiates angiogenic growth
            factor activity
  JOURNAL   J Biol Chem 281 (32), 22855-22864 (2006)
   PUBMED   16774925
  REMARK    GeneRIF: SMOC-2 is a novel angiogenic factor that potentiates
            angiogenic effects of growth factors
REFERENCE   8  (bases 1 to 2832)
  AUTHORS   Challen,G., Gardiner,B., Caruana,G., Kostoulias,X., Martinez,G.,
            Crowe,M., Taylor,D.F., Bertram,J., Little,M. and Grimmond,S.M.
  TITLE     Temporal and spatial transcriptional programs in murine kidney
            development
  JOURNAL   Physiol Genomics 23 (2), 159-171 (2005)
   PUBMED   15998744
REFERENCE   9  (bases 1 to 2832)
  AUTHORS   Vannahme,C., Gosling,S., Paulsson,M., Maurer,P. and Hartmann,U.
  TITLE     Characterization of SMOC-2, a modular extracellular calcium-binding
            protein
  JOURNAL   Biochem J 373 (Pt 3), 805-814 (2003)
   PUBMED   12741954
REFERENCE   10 (bases 1 to 2832)
  AUTHORS   Choi,J.D., Underkoffler,L.A., Collins,J.N., Marchegiani,S.M.,
            Terry,N.A., Beechey,C.V. and Oakey,R.J.
  TITLE     Microarray expression profiling of tissues from mice with
            uniparental duplications of chromosomes 7 and 11 to identify
            imprinted genes
  JOURNAL   Mamm Genome 12 (10), 758-764 (2001)
   PUBMED   11668390
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB840063.1, AK030958.1 and BY690973.1.
            
            On Nov 15, 2007 this sequence version replaced NM_022315.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159749.1, AK030958.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                BB840063.1         2-32
            32-2807             AK030958.1         1-2776
            2808-2832           BY690973.1         373-397
FEATURES             Location/Qualifiers
     source          1..2832
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 8.95 cM"
     gene            1..2832
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /note="SPARC related modular calcium binding 2"
                     /db_xref="GeneID:64074"
                     /db_xref="MGI:MGI:1929881"
     exon            1..294
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            295..466
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            467..573
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            574..673
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            674..721
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            722..772
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            773..847
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            848..1034
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1117
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1220
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1495
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1536
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..2832
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2792..2797
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /note="hexamer: ATTAAA"
     polyA_site      2810
                     /gene="Smoc2"
                     /gene_synonym="1700056C05Rik; 5430426J21Rik; Smoc2l"
                     /note="major polyA site"
ORIGIN      
        1 ggggaaacta gggctgtttg acagcagcag cggcagttcg gggagcgccg gccagagcgc
       61 acggaggggc cgtgcggtct ccaccagcgg ccataggacc gcggagcagt tctagcccgc
      121 tcgcccgcac gttcgcacac cggatcttcg ccgagtgcca gggcgcagcg cgtggggcgt
      181 ctgcctcgct tggtcccctc cagcgtcacc atgctgccgc cacagctgtg ctggctgccg
      241 ctgctcgctg ccttgctgcc gccggtgccc gcgcagaagt tctcagcgct cacgttcttg
      301 agagtcgatc aagacaaaga cagagactgc agcctggact gcccaagctc ccctcagaag
      361 ccactctgtg cctcggacgg gaggaccttc ctgtcccgat gtgagttcca gcgggccaag
      421 tgcaaagatc cacagctgga gatcgctcac cgtgggaatt gcaaagatgt gtccaggtgt
      481 gtggctgaga ggaagtatac ccaggagcag gcccggaagg agttccagca agtgttcatt
      541 ccagaatgca atgatgacgg cacctacagt caggtccagt gtcacagcta cacaggatac
      601 tgttggtgtg ttacaccaaa tggaagaccc atcagtggca ctgctgtggc ccacaagaca
      661 cccaggtgcc ccggttcaat aaatgaaaag gtgccgcagc gggaaggagc agggaaagca
      721 gatgatgctg cagccccagc attggagact cagccccaag gagatgaaga agatattgcc
      781 tcacgctacc ctacactctg gaccgagcaa gttaagagtc ggcagaacaa gaccaataaa
      841 aattcagcat cctcctgtga tcaggagcat cagtcagctc ttgaggaagc caagcagccc
      901 aagaatgaca atgtagtgat ccccgagtgt gcacatggtg gtctctacaa gccagtgcaa
      961 tgccatccat ccaccggata ctgctggtgt gtgctagtgg acactggacg gcccattccc
     1021 gggacctcca caaggtatga gcaacctaag tgtgacaaca cagcccgagc tcacccagcg
     1081 aaggcccggg acctgtacaa gaacaggcca ctgcagggtt gtcctggtgc caaaaagcac
     1141 gagtttctga caagtgtcct ggatgcgctc tccacagaca tggttcatgc cgtctctgac
     1201 ccctcttcct cttctggcag gctgtcagag ccagacccca gccacaccct ggaggagagg
     1261 gttgtacatt ggtacttcaa gctgcttgat aagaactcta gtggagacat tggcaagaag
     1321 gagatcaaac cctttaagag gttcctgcga aagaaatcca agcccaaaaa gtgtgtgaag
     1381 aagtttgtgg agtactgcga catgaacaat gacaagtcca tcaccgtgca ggagctcatg
     1441 ggctgcttgg gtgtcaccag agaggagggt aaagccaaca ccaggaagcg ccacaccccc
     1501 agaggaaatg ctgaaagttc ttcttctaat agacagccca ggaaacaagg atgaacggct
     1561 gactactcaa gacagttcct agacatgtgg gaattttccc tcaccaaaga gcaattaaaa
     1621 acaaaaaaca tatagtattt gcactttgta ctttaaatgt aaattcactt tgtagaaatg
     1681 agatatttaa acggactgtt gtgatctgtg aaaacggaag gctggcttcg ggaaattaat
     1741 cacatacaat gtatgtgtcc ttgtttgacc ttcaagatct gtgctggtgg ggtgggtttt
     1801 aaatgcattt caacttcact tcctcgtccc tctgtggagg gcctggttta ttcccttgcc
     1861 ctttcctctg cctgcagtct ccgttggctt gctctccgtg ctcttgatgc cagccagagc
     1921 ctaccgtatc cttagaagct tgcagtggtt gcctgtttca taaagttttg ctctctagag
     1981 atgtcactca caccatgggt cacacaggca ctagctcagg catagcctta acttccagta
     2041 gcccctgctt gagactatgc tgttaggctc cagttttagc ttctgcttga gccaacccta
     2101 ctgttaaatc cccggggagc tgaatggaca agcagccaga gagtcctctt tcagagagca
     2161 catctaactc tggcctgccg actccatctc attggcccag gaaggatcca gtctacctgc
     2221 ctcacttctg agtgcctggg ccatcctgct agggtccact ggaaaggaaa aatgccttct
     2281 acagagatca tggaccacat cctgaggaag gcacagctag actacatcgt cccaagagtg
     2341 ctgaacaaca ggcagctgag aatgtcaatt tcattttgtg gaggcatcgg gtttgaggga
     2401 attcacccaa ggccactatg ggatgaaggt tatgaactgg atgaccatac tgtgagagac
     2461 tgaactagat tgggtgtatg gctggctgtc actttctgac ctaggtcagt ctgtactctc
     2521 tgttctcaag gaacagtggc agatgggagg agagctgggg caattctttc agattgtggt
     2581 ttatatggga aattgttcat ggtccccagc ctctcaatgt atgtctgtag atgcattgtg
     2641 aacgcatgct gcagaaggcc tttgctcatt tgaactgtgt agaggcaaga agtgaccggc
     2701 tcatgtcaat gctgtctaca aacgagtatg atcctaactg ttttggataa tcttttatat
     2761 ttctgaactc tgaatttaat cattttatta gattaaaata tgcgattaaa ttgtgtgagt
     2821 cttcttttca gc
//
