LOCUS       NM_001384269            1858 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Mus musculus small integral membrane protein 43 (Smim43), mRNA.
ACCESSION   NM_001384269
VERSION     NM_001384269.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1858)
  AUTHORS   Fu,H., Wang,T., Kong,X., Yan,K., Yang,Y., Cao,J., Yuan,Y., Wang,N.,
            Kee,K., Lu,Z.J. and Xi,Q.
  TITLE     A Nodal enhanced micropeptide NEMEP regulates glucose uptake during
            mesendoderm differentiation of embryonic stem cells
  JOURNAL   Nat Commun 13 (1), 3984 (2022)
   PUBMED   35810171
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117584.11.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK043581.1, SRR5189673.241891.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: translation inferred from conservation
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-249               AC117584.11        168998-169246
            250-364             AC117584.11        169943-170057
            365-1858            AC117584.11        173290-174783
FEATURES             Location/Qualifiers
     source          1..1858
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 17.48 cM"
     gene            1..1858
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /note="small integral membrane protein 43"
                     /db_xref="GeneID:100503068"
                     /db_xref="MGI:MGI:3650339"
     exon            1..249
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..213
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /note="nodal enhanced mesendoderm micropeptide"
                     /codon_start=1
                     /product="small integral membrane protein 43"
                     /protein_id="NP_001371198.1"
                     /db_xref="GeneID:100503068"
                     /db_xref="MGI:MGI:3650339"
                     /translation="MEWKLNLLLYLALFFFLLFLLFLLLFVVIKQLKNSVANTAGTLQ
                     PGRLSLHREPWGFNNEQAV"
     exon            250..364
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /inference="alignment:Splign:2.1.0"
     exon            365..1858
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1733..1738
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /note="hexamer: AATAAA"
     polyA_site      1757
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /note="major polyA site"
     regulatory      1837..1842
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /note="hexamer: AATAAA"
     polyA_site      1858
                     /gene="Smim43"
                     /gene_synonym="Gm11549; NEMEP"
                     /note="major polyA site"
ORIGIN      
        1 accgcccggg cggcgcccag catggagtgg aagctgaatc tgctgctcta cctagcgctc
       61 ttcttctttc tgctcttcct cctgttcctc ctgctcttcg tggtcatcaa gcagctgaag
      121 aactcggtgg ccaatacggc cgggaccctg caacccgggc gcctgtccct gcaccgggag
      181 ccgtggggtt tcaataacga gcaagctgtg tgacccagct ggcagggttt cagctccgcc
      241 gggattcaga tctatgtcat cgggacccag actggtaccc ttgaccggtg acacccagga
      301 ccgaaactcc tatcacagcc taggagccct gcaaagccgg ggagtggagg agatcttgca
      361 aaagattctt atgtgatctc cgtggctccc caatagaagg aggaagcagg gaagaaaaca
      421 gaatgtgcct gtctgagtcc atcttccttc taaagagttt cccggggacc aggactacgt
      481 cacgggccac tgtcttttaa caatatggat gctgttgcct tcaatcaaaa cccaagctct
      541 ctagattagg acaaagaatc ctgggtggac aagatccaga agtctatgct ctagtacaaa
      601 gcacagttgt gcagaaagca gtgttcaaga tggaactcct ggttcccaca cagccccacc
      661 gatgtggctg agcagagtga cgatgtctcc ctagttctca agaaatattt gtcaggactg
      721 gcttcctctc tggtcagctg actcccctgt accaggattt tctaggcatg tagcctggaa
      781 gccttacatt tgtgtgtgtt gggggatctg gaggttgagg gggtcttcat aatctcctca
      841 cggaactttg gtaacagatc aacataggtt gttttctttt gctccttttt ggtcccctcc
      901 atcacgttcc agttagttca attttggtgg cagctaagtt tgtgtatttg atccctataa
      961 aggccatccc ttccatgcac aaggaaagac actctgctca gaaaggctac ctctcttcct
     1021 tccaccctcg atccaggaat atcccgggag attgcctctc gagctgcttc tactcacagc
     1081 ctacgtactg gccaagccga gggagaagaa acacttccca cacccagagc tgtgcaaaag
     1141 aactttctgt gatatgaaac tgttctatat ctgtggtgcc caatacggca actactagtc
     1201 acatgtgtct agtaaacact gaaatatggc taacggggct tagcttttat ttaatttcac
     1261 ccgagacagc cacttggggc tagtggctat tgtatgtaca gttcacacca ttctcgtgtg
     1321 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtattag agtcaaagag gggaggtggc
     1381 tgctagccat gaactccaca tcccatggtc ttcattgttt ttcttgcttt cagtttttct
     1441 ccttgatgaa aaagaaagtc agtatgttag ctctaaattg agaatgctac catctaccta
     1501 ttgcatgtct tcttgtacca aatgagatag gtttcagtga taattgacca tggtaaaaat
     1561 ggaagtgttg attcactaca tctccatatt cccagtcctt gcccctgacc aaggtcacat
     1621 tgtcctaggc actttattcc attttagttc tctttttaat attgtgaatc ccaagcaatt
     1681 attgtatatg tttttcaaaa tacctaatgg tttatatttt ttaaggctgt aaaataaaaa
     1741 ttgacaatta catgtaactc aggttttgtg tgtatgtgtg tctgtgcaat ttttagtaac
     1801 ttactaccca aactttattg tattgattag gatatgaata aatggaaagt gatattga
//
