LOCUS       NM_001253797             435 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus small integral membrane protein 22 (Smim22),
            transcript variant 3, mRNA.
ACCESSION   NM_001253797
VERSION     NM_001253797.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Tamplin OJ, Cox BJ and Rossant J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163723.3 and CJ237462.1.
            
            Transcript Variant: This variant (3) uses an alternate splice site
            in the 3' coding region, compared to variant 1. The encoded isoform
            2 is shorter than isoform 1. Both variants 3 and 4 encode the same
            isoform (2).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF382750.1, CK594508.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AC163723.3         57127-57130
            5-432               CJ237462.1         2-429
            433-435             AC163723.3         58118-58120
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 2.49 cM"
     gene            1..435
                     /gene="Smim22"
                     /gene_synonym="EG432995; Gm5480"
                     /note="small integral membrane protein 22"
                     /db_xref="GeneID:432995"
                     /db_xref="MGI:MGI:3643379"
     exon            1..103
                     /gene="Smim22"
                     /gene_synonym="EG432995; Gm5480"
                     /inference="alignment:Splign:2.1.0"
     exon            104..248
                     /gene="Smim22"
                     /gene_synonym="EG432995; Gm5480"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..373
                     /gene="Smim22"
                     /gene_synonym="EG432995; Gm5480"
                     /note="isoform 2 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="small integral membrane protein 22 isoform 2"
                     /protein_id="NP_001240726.1"
                     /db_xref="CCDS:CCDS70681.1"
                     /db_xref="GeneID:432995"
                     /db_xref="MGI:MGI:3643379"
                     /translation="MGLSDEELRQELQATAEEVLGRLRSRQLFQSEWDVAAFVVFLTF
                     VGTVLLLLLLVFVHCCCCCCCNTSPRPRKEKRNGVDNLALEP"
     exon            249..331
                     /gene="Smim22"
                     /gene_synonym="EG432995; Gm5480"
                     /inference="alignment:Splign:2.1.0"
     exon            332..435
                     /gene="Smim22"
                     /gene_synonym="EG432995; Gm5480"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaagcagt gtgagttcct aggacctacc tggcctgggg gggaaggggt gccactagag
       61 gcaggtgggg gcactggaat cagctttgct ggggagagag gaggtggctg agatggggct
      121 ttctgatgag gagctgaggc aggagctgca ggccactgca gaggaagtac tggggaggct
      181 gaggagccgg cagctcttcc agtcggaatg ggacgtcgct gcctttgtgg tctttctcac
      241 atttgtgggc actgtgctgt tgttgctgtt gctggtcttt gtccattgct gctgttgttg
      301 ctgctgcaac acctccccca ggccccggaa ggaaaagcgc aatggtgtgg ataacttggc
      361 cctggaacct taatgctaac ttgcccttgg catgggtcct gctggatgac agtaacagag
      421 ccaatgtttg ccaaa
//
