LOCUS       NM_138743                517 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus small integral membrane protein 11 (Smim11), mRNA.
ACCESSION   NM_138743
VERSION     NM_138743.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 517)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   4  (bases 1 to 517)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   5  (bases 1 to 517)
  AUTHORS   Reymond,A., Friedli,M., Henrichsen,C.N., Chapot,F., Deutsch,S.,
            Ucla,C., Rossier,C., Lyle,R., Guipponi,M. and Antonarakis,S.E.
  TITLE     From PREDs and open reading frames to cDNA isolation: revisiting
            the human chromosome 21 transcription map
  JOURNAL   Genomics 78 (1-2), 46-54 (2001)
   PUBMED   11707072
REFERENCE   6  (bases 1 to 517)
  AUTHORS   Verlaet,M., Deregowski,V., Denis,G., Humblet,C., Stalmans,M.T.,
            Bours,V., Castronovo,V., Boniver,J. and Defresne,M.P.
  TITLE     Genetic imbalances in preleukemic thymuses
  JOURNAL   Biochem Biophys Res Commun 283 (1), 12-18 (2001)
   PUBMED   11322760
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK004538.1 and BM932344.1.
            
            On Feb 1, 2007 this sequence version replaced NM_138743.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ175180.1, CK795223.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AK004538.1         1-52
            53-517              BM932344.1         37-501
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 53.55 cM"
     gene            1..517
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /note="small integral membrane protein 11"
                     /db_xref="GeneID:68936"
                     /db_xref="MGI:MGI:1916186"
     exon            1..41
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /inference="alignment:Splign:2.1.0"
     exon            42..151
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /inference="alignment:Splign:2.1.0"
     CDS             140..307
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /note="protein FAM165B; family with sequence similarity
                     165, member B; small integral membrane protein 11A"
                     /codon_start=1
                     /product="small integral membrane protein 11"
                     /protein_id="NP_620082.1"
                     /db_xref="CCDS:CCDS37404.1"
                     /db_xref="GeneID:68936"
                     /db_xref="MGI:MGI:1916186"
                     /translation="MNWKVLEHVPLLLYILAAKTLILCLAFAGVKMYQRRSLEGKLQA
                     EKRKQSEKKAS"
     exon            152..320
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /inference="alignment:Splign:2.1.0"
     exon            321..500
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      480..485
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /note="hexamer: AATAAA"
     polyA_site      500
                     /gene="Smim11"
                     /gene_synonym="1190017O12Rik; C21orf51; Fam165b; Smim11a"
                     /note="major polyA site"
ORIGIN      
        1 ggtttgtgag cagcaagcga ggaggccccg ccgccctgag tatcagaact tccagctcct
       61 tgggtccggc tttccagctg cctctcatgc ctgtgtgtaa caggtacatt ggtcagaagt
      121 gaatcacagc tggcccgcca tgaactggaa ggttcttgaa cacgtgcccc tgctgctgta
      181 tatcctggcg gcaaaaaccc tgatcctgtg cctggccttt gcgggcgtga aaatgtacca
      241 aaggagaagc ctggaaggaa aactgcaagc agagaagagg aagcagtcag agaagaaagc
      301 gagctgaaga gacattagag attttcctac ttaaatgtca gcttgggtgg actccagcag
      361 agaagagaga acaaagacgt cacagaagag gaccgcactc tggcctagac ctttaactta
      421 aatgattgac agagtggatt tttatatgtt tttagaagaa ccagtatttt gtttactgaa
      481 ataaagtaca ttattcttaa aaaaaaaaaa aaaaaaa
//
