LOCUS       NM_028887               7052 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus SMC hinge domain containing 1 (Smchd1), mRNA.
ACCESSION   NM_028887
VERSION     NM_028887.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7052)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7052)
  AUTHORS   Tapia Del Fierro,A., den Hamer,B., Benetti,N., Jansz,N., Chen,K.,
            Beck,T., Vanyai,H., Gurzau,A.D., Daxinger,L., Xue,S., Ly,T.T.N.,
            Wanigasuriya,I., Iminitoff,M., Breslin,K., Oey,H., Krom,Y.D., van
            der Hoorn,D., Bouwman,L.F., Johanson,T.M., Ritchie,M.E.,
            Gouil,Q.A., Reversade,B., Prin,F., Mohun,T., van der Maarel,S.M.,
            McGlinn,E., Murphy,J.M., Keniry,A., de Greef,J.C. and Blewitt,M.E.
  TITLE     SMCHD1 has separable roles in chromatin architecture and gene
            silencing that could be targeted in disease
  JOURNAL   Nat Commun 14 (1), 5466 (2023)
   PUBMED   37749075
  REMARK    GeneRIF: SMCHD1 has separable roles in chromatin architecture and
            gene silencing that could be targeted in disease.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7052)
  AUTHORS   Ichihara,S., Nagao,K., Sakaguchi,T., Obuse,C. and Sado,T.
  TITLE     SmcHD1 underlies the formation of H3K9me3 blocks on the inactive X
            chromosome in mice
  JOURNAL   Development 149 (15) (2022)
   PUBMED   35831949
  REMARK    GeneRIF: SmcHD1 underlies the formation of H3K9me3 blocks on the
            inactive X chromosome in mice.
REFERENCE   4  (bases 1 to 7052)
  AUTHORS   Benetti,N., Gouil,Q., Tapia Del Fierro,A., Beck,T., Breslin,K.,
            Keniry,A., McGlinn,E. and Blewitt,M.E.
  TITLE     Maternal SMCHD1 regulates Hox gene expression and patterning in the
            mouse embryo
  JOURNAL   Nat Commun 13 (1), 4295 (2022)
   PUBMED   35879318
  REMARK    GeneRIF: Maternal SMCHD1 regulates Hox gene expression and
            patterning in the mouse embryo.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7052)
  AUTHORS   Wanigasuriya,I., Kinkel,S.A., Beck,T., Roper,E.A., Breslin,K.,
            Lee,H.J., Keniry,A., Ritchie,M.E., Blewitt,M.E. and Gouil,Q.
  TITLE     Maternal SMCHD1 controls both imprinted Xist expression and
            imprinted X chromosome inactivation
  JOURNAL   Epigenetics Chromatin 15 (1), 26 (2022)
   PUBMED   35843975
  REMARK    GeneRIF: Maternal SMCHD1 controls both imprinted Xist expression
            and imprinted X chromosome inactivation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7052)
  AUTHORS   Blewitt,M.E., Gendrel,A.V., Pang,Z., Sparrow,D.B., Whitelaw,N.,
            Craig,J.M., Apedaile,A., Hilton,D.J., Dunwoodie,S.L.,
            Brockdorff,N., Kay,G.F. and Whitelaw,E.
  TITLE     SmcHD1, containing a structural-maintenance-of-chromosomes hinge
            domain, has a critical role in X inactivation
  JOURNAL   Nat Genet 40 (5), 663-669 (2008)
   PUBMED   18425126
  REMARK    GeneRIF: SmcHD1 is not required for correct Xist expression, but
            localizes to the inactive X and has a role in the maintenance of X
            inactivation and the hypermethylation of CpG islands associated
            with the inactive X.
REFERENCE   7  (bases 1 to 7052)
  AUTHORS   Blewitt,M.E., Vickaryous,N.K., Hemley,S.J., Ashe,A., Bruxner,T.J.,
            Preis,J.I., Arkell,R. and Whitelaw,E.
  TITLE     An N-ethyl-N-nitrosourea screen for genes involved in variegation
            in the mouse
  JOURNAL   Proc Natl Acad Sci U S A 102 (21), 7629-7634 (2005)
   PUBMED   15890782
REFERENCE   8  (bases 1 to 7052)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   9  (bases 1 to 7052)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 7052)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107664.8 and AC126942.4.
            
            On Aug 14, 2018 this sequence version replaced NM_028887.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.239017.1,
                                           SRR14777534.658031.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-365               AC107664.8         170506-170870       c
            366-441             AC107664.8         161121-161196       c
            442-603             AC107664.8         159289-159450       c
            604-686             AC107664.8         151945-152027       c
            687-817             AC107664.8         151132-151262       c
            818-932             AC107664.8         144259-144373       c
            933-1052            AC107664.8         144040-144159       c
            1053-1219           AC107664.8         139409-139575       c
            1220-1310           AC107664.8         137403-137493       c
            1311-1521           AC107664.8         136431-136641       c
            1522-1642           AC107664.8         132233-132353       c
            1643-1826           AC107664.8         126749-126932       c
            1827-2021           AC107664.8         124989-125183       c
            2022-2135           AC107664.8         123699-123812       c
            2136-2242           AC107664.8         122964-123070       c
            2243-2325           AC107664.8         121967-122049       c
            2326-2439           AC107664.8         121682-121795       c
            2440-2517           AC107664.8         111128-111205       c
            2518-2637           AC107664.8         110562-110681       c
            2638-2782           AC107664.8         107297-107441       c
            2783-2879           AC107664.8         102694-102790       c
            2880-2952           AC107664.8         98625-98697         c
            2953-3092           AC107664.8         95586-95725         c
            3093-3230           AC107664.8         94079-94216         c
            3231-3458           AC107664.8         90244-90471         c
            3459-3607           AC107664.8         86879-87027         c
            3608-3696           AC107664.8         85954-86042         c
            3697-3815           AC107664.8         85270-85388         c
            3816-3983           AC107664.8         82472-82639         c
            3984-4109           AC107664.8         76859-76984         c
            4110-4189           AC107664.8         75656-75735         c
            4190-4347           AC107664.8         75069-75226         c
            4348-4463           AC107664.8         73675-73790         c
            4464-4528           AC107664.8         72541-72605         c
            4529-4616           AC107664.8         66436-66523         c
            4617-4748           AC107664.8         65751-65882         c
            4749-4901           AC107664.8         65335-65487         c
            4902-5028           AC107664.8         60873-60999         c
            5029-5148           AC107664.8         60616-60735         c
            5149-5234           AC126942.4         181912-181997       c
            5235-5357           AC126942.4         180733-180855       c
            5358-5548           AC126942.4         178919-179109       c
            5549-5658           AC126942.4         177240-177349       c
            5659-5729           AC126942.4         177029-177099       c
            5730-5901           AC126942.4         172278-172449       c
            5902-6060           AC126942.4         168482-168640       c
            6061-6175           AC126942.4         167778-167892       c
            6176-7052           AC126942.4         163381-164257       c
FEATURES             Location/Qualifiers
     source          1..7052
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 41.87 cM"
     gene            1..7052
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /note="SMC hinge domain containing 1"
                     /db_xref="GeneID:74355"
                     /db_xref="MGI:MGI:1921605"
     exon            1..365
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..6203
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /note="SMC hinge domain-containing protein 1"
                     /codon_start=1
                     /product="structural maintenance of chromosomes flexible
                     hinge domain-containing protein 1"
                     /protein_id="NP_083163.3"
                     /db_xref="CCDS:CCDS28958.2"
                     /db_xref="GeneID:74355"
                     /db_xref="MGI:MGI:1921605"
                     /translation="MAAEGASDPAGLSEGSGRDGAVDGCRTVYLFDRRGKDSELGDRA
                     LQVSEHADYAGFRASVCQTIGISSEEKFVITTTSRKEITCNNFDHTVKDGVTLYLLQS
                     VDQSLLTATKERIDFLPHYDTLVKSGMYEYYASEGQNPLPFALAELIDNSLSATSRNN
                     GVRRIQIKLLFDETQGKPAVAVVDNGRGMTSKQLNNWAVYRLSKFTRQGDFESDHSGY
                     VRPLPVPRSLNSDISYFGVGGKQAVFFVGQSARMISKPIDSKDVHELVLSKEDFEKKE
                     KNKEAIYSGYIRNRKPADSAHITNDDERFLHNLIEEEKEKDSFTAVVITGVQPEHIQY
                     LKNYLHLWTRQLTHIYHYYIHGPKGNEISTAKAIGPFNNIDIEISLFEKGKTPKIINL
                     REIQDDMQTLYINTASDSFEFKAHVEGDGVVEGVIRYHPFLYDRETFPDDPCFPSKLK
                     DEDDDDDCFISEKAARGKRPIFECFWNGRLIPYTSVGDFDWCAPPKKRGLVPIECFNR
                     ISGALFTNDKFQVSTNKLTFMDLELKLKDKNTLFTRILNGQEQRMKIDREFALWLKDC
                     HEKHDKQIKFTLFKGIITRPDLPTKKQGPWATFSAIEWDGKIYKAGQLVKTIKTLPLC
                     YGSIVRFFLHGDHDGEVYATGGEVQIAMEPQALYDEIKTVPIAKLDRTVAEKTIRKYV
                     EDEMARLPDRLSVTWPEGDELLPNEVRPAGTPIGALRIEILNKKGEAMQKLPGTSHGG
                     SKKLLVELKVILHTSSGNKEIISHISQHGGKWPYWFKKMENIQKLGNYTLKLQVVLNE
                     SNADTYAGRSLPSKVIKFSVKEGKPEKFSFGLLDSPFRVGVPFNIPLELQDEFGHTTQ
                     LLSDIEPVLEASGLSLHYEGITKGPNCVIQGVVAKGPVNSCQGKNFNLKVILPGLKED
                     SQILKIRLLPGPPHQLKVKPDSEVLVIENGTAFPFQVEVVDESDNITAQPKLIVHCKF
                     LGAPNLPVYTVDCSSSGTSILTGSPIQVQNIKKDQKTLTARIEIPSCKDVSPVEKTIK
                     LLPSSHAACLQIFSVEEQKAIQIKHQDEVTWVAGDVIRNLIFQMYDEGEREINITPSL
                     AEKIKVNWTPEVNKEHLVQGLLPDVQVPTSVKDVRYCHVSFQDDHVCLESAFTVRPLP
                     DDPKHLKCELKGGKTVQMGQELQGEIVVIIADQYGNQISSFSPDSLSTLSITGDGLDS
                     SNLKITLEANSQSVSVQGIRFTPGPPGPKDLCFTWREFSDFLRVQLVSGPPTKLLLMD
                     WPELKESIPVINGRQLENPLIVQLCDQWDNPALVPNVKICLIKASSLRLLPSNQQHKT
                     DDKGRANLGVFTVCAPRGEHTVQVKGVYNKSTIEGPTIKLTILPDPEKPIRLNVKYDQ
                     DASFIAGDIFTDFMVSVISESGSVIKNINPTRISMKMWKLSSGMSRPPANAETFSCNK
                     IKGNDKEDGCFYFREKTIPNKVGAYCIQFDFMIDKTNILSSQQVIVDVLPNQPMKLVP
                     DSQPATPAVSNVRSIASRTLVKDLRLSITDNYGNHTGMDLVGTVVATIKGFNEEDTDT
                     PLFIGKVRTLEFPFVKGSAEITTLVLAENSPGRDSTEYFIIFEPRLSTVSGTLESYSL
                     PFMFYNDVKKQQQMAALTKEKDELSKSITMYRSLFDANKQLVDEMKCQAEEAKLKETQ
                     LRNELKAYNIDIPATQQTTHIEALLEKKITEQNELKKRPRRLCTLPNYTKRSGDILGK
                     IAHLAQIEDDRAAMVISWHLASDMDCVVTLTTDAARAIYDETQGRQQVLPLDSIYRKT
                     LPDWKRPLPHFRNGKLHFKPFGNPVFARDLLTFPDNIEHCETVFGMLLGDTIILDNLD
                     AANHYRKEVVKITHCPTLLTRDGDRIRSNGKFGGLQNKAPPMDKLRGMVFGAPVPKQC
                     VVLGKQIDLIQQYRTALYRLSSVNEDLDNQLQYLHTPDMKKKKQELDEQEKSLKRIEQ
                     KLGMTPVRRCNESLCHSPKIEVTECPIPTKRMRRESTRQNRRPKGDVPN"
     exon            366..441
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            442..603
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            604..686
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            687..817
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            818..932
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1052
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1219
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1310
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1521
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1642
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1826
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1827..2021
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2135
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2136..2242
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2243..2325
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2439
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2440..2517
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2518..2637
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2638..2782
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2783..2879
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2880..2952
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            2953..3092
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            3093..3230
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            3231..3458
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            3459..3607
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            3608..3696
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            3697..3815
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            3816..3983
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            3984..4109
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4110..4189
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4190..4347
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4348..4463
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4464..4528
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4529..4616
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4617..4748
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4749..4901
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            4902..5028
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5029..5148
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5149..5234
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5235..5357
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5358..5548
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5549..5658
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5659..5729
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5730..5901
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            5902..6060
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            6061..6175
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     exon            6176..7052
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7019..7024
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /note="hexamer: AATAAA"
     polyA_site      7052
                     /gene="Smchd1"
                     /gene_synonym="4931400A14Rik; mKIAA0650; MommeD1"
                     /note="major polyA site"
ORIGIN      
        1 ggcagaagcg cgtttgaatc ggttcccggg ttacttcccg gccgctgccc acagtcggtg
       61 ctgcgcggcc cgctgaggct cggagccgcg gcggctggag ccgagggcac gcgcggggtc
      121 ggtgtctccg ggaagcgcgc ccgagagccg cagggccttc tctttttttc tccctcaaca
      181 tggcagcgga gggcgccagc gatcccgccg gcctctcgga gggatctggg agagatggcg
      241 ccgtcgacgg ctgtaggacg gtgtacttgt ttgaccggcg cgggaaggac tcggagctag
      301 gggatcgcgc actgcaggtc tcggagcacg cggactacgc ggggttccgc gcttctgtgt
      361 gtcagacaat tggcatttca tctgaagaaa agtttgttat tacaactaca agtaggaaag
      421 aaattacctg taataatttt gaccacactg ttaaagatgg agtcactctg tacctgctgc
      481 agtcagttga ccagtcacta ctgacggcga cgaaagaaag aattgacttt ctacctcact
      541 acgacactct agttaaaagt ggcatgtatg agtattatgc gagtgaagga cagaatcctt
      601 tgccatttgc tcttgcagag ttaatcgaca attcattgtc agctacttct cgaaataatg
      661 gtgttaggag aatacagatc aaattgcttt ttgatgaaac acaaggaaaa cctgctgtcg
      721 cagtggtaga taatggaaga ggaatgacct ctaagcagct taacaactgg gctgtgtata
      781 ggctgtcaaa atttacaaga caaggtgact ttgaaagtga tcactcaggg tatgtccggc
      841 cattaccagt accacgcagt ttgaacagtg acatttccta ttttggtgtt ggaggcaaac
      901 aggctgtttt ctttgttggg caatcagcca gaatgataag caagcctatc gactccaagg
      961 atgttcatga gctggtgctt tctaaagaag attttgagaa gaaggaaaaa aataaagagg
     1021 cgatatatag tggatatatt agaaacagaa agccagctga ttctgctcac attacaaatg
     1081 atgatgaaag attcctacac aatcttattg aggaagagaa agagaaagac agctttacag
     1141 ctgtggttat tacaggggta cagccagaac acatacagta cttgaaaaat tatttacatc
     1201 tttggacacg acagctaacg catatttatc attactatat tcatggacca aaaggaaatg
     1261 aaataagtac agccaaagcc attggacctt tcaacaatat tgatattgaa atttctttgt
     1321 ttgaaaaggg gaagacacct aagattatca acctaaggga aatacaagat gacatgcaga
     1381 cattgtatat aaacacagcg tctgatagtt ttgagttcaa ggctcacgtt gaaggagacg
     1441 gtgtagtgga aggggttatc cggtaccatc ccttcttata tgatagagaa acctttcctg
     1501 atgacccatg ctttccatca aagctaaagg atgaagacga cgatgatgac tgtttcatat
     1561 ccgagaaagc agctcgaggg aagaggccga tctttgagtg tttttggaat ggacggttaa
     1621 taccatatac atcagtagga gactttgact ggtgtgctcc tcctaagaag agagggcttg
     1681 tcccaattga gtgctttaat agaatatctg gtgcattatt cactaatgac aaatttcagg
     1741 tcagcacaaa taaactgaca tttatggatc ttgagctgaa attgaaagat aagaacaccc
     1801 tctttacaag aatcttaaat ggacaggagc agagaatgaa aattgacaga gaatttgctt
     1861 tatggctgaa ggattgtcat gaaaagcatg acaaacaaat aaaattcacg ctttttaaag
     1921 gaataattac ccgtccagat cttcccacta aaaagcaagg cccctgggca acattttcag
     1981 caatagaatg ggatgggaaa atatacaaag caggccaact ggtcaagaca atcaagacac
     2041 ttcctctctg ttatggaagc attgttagat ttttccttca tggtgatcat gatggagaag
     2101 tgtatgcgac gggaggtgaa gttcagattg ccatggaacc ccaggcactg tatgatgaaa
     2161 taaaaactgt gcccattgca aagctggata ggacagtagc cgagaaaaca attaggaaat
     2221 atgtagaaga tgaaatggca aggctccctg atagattgtc tgtaacttgg cctgaaggag
     2281 atgaattatt gccaaatgaa gttaggcctg ctggaacacc aatcggtgca ttaagaattg
     2341 aaattctaaa caaaaagggg gaagcaatgc agaaactccc agggacaagt catggagggt
     2401 caaagaagct gctggtggaa cttaaagtca tactgcacac ttcaagtgga aataaagaaa
     2461 tcatttcaca tatcagtcag catggaggga aatggcctta ctggtttaaa aaaatggaaa
     2521 atatccagaa actgggtaat tatacattga aattacaagt tgtattgaat gaaagtaatg
     2581 cagataccta tgcaggaaga tcactaccgt ccaaagtaat taaattctct gttaaagagg
     2641 gcaagccaga aaagttttcg tttggtcttc tggactctcc tttccgtgtt ggagttccat
     2701 ttaatattcc tctggagtta caggatgaat ttggtcacac tacccaacta ttgtctgata
     2761 ttgagccagt tcttgaagca agtggtctgt ctttacatta tgaaggaata accaaaggcc
     2821 cgaattgtgt aattcaaggt gtcgtagcta aaggtccagt taactcttgc cagggcaaga
     2881 attttaatct gaaggttatt cttcctggtt taaaagaaga ctcacagatt ttgaagatta
     2941 gattgctacc tggtccccct catcaactaa aggtgaaacc tgactcagaa gttctggtta
     3001 tagagaatgg aacagctttc ccatttcagg tggaagttgt ggatgagtca gacaacataa
     3061 cagcacaacc aaagctgatc gtccactgta agtttctagg tgctccaaac ctaccagtct
     3121 atactgtgga ttgcagtagc tctggaacta gcatcctaac agggtcaccc attcaagttc
     3181 agaacattaa gaaagaccag aagacactga ccgccaggat tgagatacct agctgtaaag
     3241 atgtgtcacc tgttgaaaag acgatcaagt tacttcccag tagccacgct gcttgcctgc
     3301 agatctttag tgtagaggag caaaaggcga tccagatcaa acatcaggat gaggttactt
     3361 gggtagcagg tgatgtaata cgcaatctaa tttttcaaat gtatgacgaa ggagaaagag
     3421 aaatcaatat tacaccatcc ttggcagaaa aaattaaggt taattggact cctgaggtga
     3481 acaaagaaca tttggtacaa ggtctccttc ctgatgtgca agtaccaaca tctgtgaaag
     3541 atgtccgcta ctgccatgtt tctttccaag atgaccacgt gtgtctggag agcgccttta
     3601 cagtaagacc acttcctgat gatcccaaac atttaaaatg tgaattaaaa ggaggaaaaa
     3661 cagtgcagat gggccaagag cttcaaggag aaatagttgt aataattgca gatcagtatg
     3721 gaaatcagat ttcatcattt tcacctgatt ccttatctac tttgtcgatt actggagatg
     3781 gccttgacag ctcaaacttg aaaatcacct tggaggccaa ctcacagagc gtaagtgtgc
     3841 aaggcatcag gtttactcca gggcctcctg gacccaagga tctgtgtttt acttggcgag
     3901 agttttctga ctttctgcgc gtgcaactgg tttctggacc tccaaccaag ctgctgctta
     3961 tggactggcc agagctgaaa gagtccattc ctgtgattaa tggaagacaa ttagagaacc
     4021 ctctcattgt tcaactttgt gatcagtggg ataatcctgc tttagtccca aacgttaaaa
     4081 tatgtctcat aaaagcaagc agcttaaggc tactaccttc aaaccagcag cataaaacag
     4141 atgataaggg cagagctaat ttgggggtgt tcactgtttg tgctccaagg ggagaacaca
     4201 ctgtgcaggt taaaggtgtc tataataaga gcactataga agggcctaca attaagttaa
     4261 caattcttcc agaccctgaa aagcccattc gcctcaatgt taaatatgac caagatgcct
     4321 cttttatagc aggggacata ttcactgatt ttatggttag tgtgatttct gaaagtggta
     4381 gtgtcatcaa aaatattaat ccaacacgta tttccatgaa aatgtggaag ctgtccagtg
     4441 gcatgagccg gccaccagca aatgcagaaa cctttagttg taataaaata aaaggtaacg
     4501 acaaggaaga tggctgcttc tatttcaggg agaaaactat ccctaacaag gtgggagcat
     4561 attgtatcca gtttgatttc atgattgata agacaaatat tctaagcagc caacaggtta
     4621 tagttgatgt tctccccaac cagcctatga agttggttcc tgacagccaa ccagctaccc
     4681 cagctgtttc taatgtccgt tcaattgcca gcaggacctt ggtcaaagac ctgcgcctca
     4741 gtatcacaga taattatggt aatcacactg gaatggatct ggttggcact gtagtagcaa
     4801 ccattaaagg ctttaatgag gaggacactg ataccccact cttcatcggg aaggttagga
     4861 cgcttgagtt tccctttgtg aaaggctctg ctgaaatcac gactctagtg ctggcagaaa
     4921 atagtcctgg aagggatagt actgaatact ttattatctt tgagcctcgg ctgtcaactg
     4981 tatcaggaac attagaatca tatagcctgc catttatgtt ttacaatgat gttaagaagc
     5041 agcaacaaat ggcagcgctt acgaaggaga aggacgagtt atccaagtcc atcactatgt
     5101 acagaagtct cttcgatgcc aacaagcagc ttgtggatga aatgaaatgc caagctgaag
     5161 aagcaaagtt aaaagagacc cagctacgaa atgaactaaa agcgtacaat attgatattc
     5221 ctgcgacaca acagacaact catattgaag cacttttgga aaaaaagata acagaacaga
     5281 acgagcttaa aaagaggccc agaaggttgt gtactcttcc aaactacact aaacgcagtg
     5341 gagatatttt gggaaagatt gcacatctag cacaaattga agatgatcga gctgccatgg
     5401 ttatctcttg gcatctggca agtgacatgg actgtgtggt taccctaacc actgatgccg
     5461 cacgcgctat ctatgacgaa actcaaggtc gccagcaagt gttgcccctt gattctattt
     5521 acaggaaaac tcttccagat tggaaaagac ctctacctca tttccgaaat ggtaaattac
     5581 actttaagcc ctttggaaat ccagtctttg cccgagattt gttaacattc ccagataata
     5641 ttgaacattg tgaaacagtt tttggtatgc tgttaggaga caccattatt ttggataatc
     5701 tggatgcagc caatcattat agaaaagagg ttgttaaaat cacacactgc cccacactcc
     5761 tgactagaga tggagataga attagaagta atgggaagtt tgggggcctt cagaataaag
     5821 ctccgccaat ggacaaactt cggggaatgg tcttcggagc tccagtacca aagcagtgtg
     5881 tggtcttggg gaaacaaata gatcttattc agcagtatcg cactgctctg tacaggctga
     5941 gctctgtgaa cgaggacttg gacaatcagc tgcagtacct tcacactcct gatatgaaga
     6001 agaaaaagca agaacttgat gaacaggaaa aaagtctgaa acgaatagag cagaaactcg
     6061 gaatgactcc tgtgcgcagg tgtaatgagt cactttgtca ctcaccaaag attgaggtga
     6121 cagagtgccc aatccctact aaaagaatga gaagagaatc caccagacag aatagaaggc
     6181 caaaaggtga cgtaccaaac tgagcatttc tgaagactat gataatcctg gcaagaattt
     6241 cctgttcctc caaatgggcc tggaagccat tgaagctatt caactttcag aatctcatgg
     6301 ggcagcacaa atttcctggg gtcattgcag tcgttgggcc cgtcggtggc tggcttgcaa
     6361 atgtacactt ttacccagtg gtggtcatcc cagccctggg acgtttcctg ccctgaagac
     6421 aacttcctgc tcctcagcat aatcatgaac atattagaac tgtttcttaa aaacagcctt
     6481 ttttattgcc tttttctgga cttatttaac aaacatgttt tgtcttttgt gtaaggaaaa
     6541 ttctagaact agatatttaa ctgtaaatat atgtggaaag ttgaattctg cattaaaaca
     6601 gagaaagcac aggtgtctgg gaatttaaat gttcagatac acaaaaacat tggtgagaat
     6661 aggatagcct aaagattgtg tcctgtatga gttggtgata ggacagccta aagactgtat
     6721 cctgtatata agtaagatat gcagcagcac ttggctttaa ttctacattt gcattatttt
     6781 ctaatttttt acaactattt ttaagagatt aaagaaaaca agaattcaaa gagtttgtta
     6841 gggatatgtt atataaacat ctaagctgtg catttattca aactaacata cgccgtgtgt
     6901 gtctctgtaa gtgcaagact tttgctctgt gaatttattt tgtaaggaat acttttggta
     6961 caattttctg ttccaggaaa tgtgtgtttt taatccttcc tgattatgca gcaaggttaa
     7021 taaacaacaa tcatttctcc tccccaaaaa aa
//
