LOCUS       NM_007790               4851 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus structural maintenance of chromosomes 3 (Smc3), mRNA.
ACCESSION   NM_007790
VERSION     NM_007790.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4851)
  AUTHORS   Zhang,B., Zhu,Y., Zhang,Z., Wu,F., Ma,X., Sheng,W., Dai,R., Guo,Z.,
            Yan,W., Hao,L., Huang,G., Ma,D., Hao,B. and Ma,J.
  TITLE     SMC3 contributes to heart development by regulating super-enhancer
            associated genes
  JOURNAL   Exp Mol Med 56 (8), 1826-1842 (2024)
   PUBMED   39085358
  REMARK    GeneRIF: SMC3 contributes to heart development by regulating
            super-enhancer associated genes.
REFERENCE   2  (bases 1 to 4851)
  AUTHORS   Lu,Z., Wang,Y., Assumpcao,A.L.F.V., Liu,P., Kopp,A., Saka,S.,
            Mcilwain,S.J., Viny,A.D., Brand,M. and Pan,X.
  TITLE     Yin Yang 1 regulates cohesin complex protein SMC3 in mouse
            hematopoietic stem cells
  JOURNAL   Blood Adv 8 (12), 3076-3091 (2024)
   PUBMED   38531064
  REMARK    GeneRIF: Yin Yang 1 regulates cohesin complex protein SMC3 in mouse
            hematopoietic stem cells.
REFERENCE   3  (bases 1 to 4851)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 4851)
  AUTHORS   Bastos,N., Castaldo,S.A., Adem,B., Machado,J.C., Melo,C.A. and
            Melo,S.A.
  TITLE     SMC3 epigenetic silencing regulates Rab27a expression and drives
            pancreatic cancer progression
  JOURNAL   J Transl Med 21 (1), 578 (2023)
   PUBMED   37641131
  REMARK    GeneRIF: SMC3 epigenetic silencing regulates Rab27a expression and
            drives pancreatic cancer progression.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4851)
  AUTHORS   Meyer,A.E., Stelloh,C., Pulakanti,K., Burns,R., Fisher,J.B.,
            Heimbruch,K.E., Tarima,S., Furumo,Q., Brennan,J., Zheng,Y.,
            Viny,A.D., Vassiliou,G.S. and Rao,S.
  TITLE     Combinatorial genetics reveals the Dock1-Rac2 axis as a potential
            target for the treatment of NPM1;Cohesin mutated AML
  JOURNAL   Leukemia 36 (8), 2032-2041 (2022)
   PUBMED   35778533
REFERENCE   6  (bases 1 to 4851)
  AUTHORS   Prieto,I., Suja,J.A., Pezzi,N., Kremer,L., Martinez-A,C.,
            Rufas,J.S. and Barbero,J.L.
  TITLE     Mammalian STAG3 is a cohesin specific to sister chromatid arms in
            meiosis I
  JOURNAL   Nat Cell Biol 3 (8), 761-766 (2001)
   PUBMED   11483963
REFERENCE   7  (bases 1 to 4851)
  AUTHORS   Darwiche,N., Freeman,L.A. and Strunnikov,A.
  TITLE     Characterization of the components of the putative mammalian sister
            chromatid cohesion complex
  JOURNAL   Gene 233 (1-2), 39-47 (1999)
   PUBMED   10375619
REFERENCE   8  (bases 1 to 4851)
  AUTHORS   Ghiselli,G., Siracusa,L.D. and Iozzo,R.V.
  TITLE     Complete cDNA cloning, genomic organization, chromosomal
            assignment, functional characterization of the promoter, and
            expression of the murine Bamacan gene
  JOURNAL   J Biol Chem 274 (24), 17384-17393 (1999)
   PUBMED   10358101
REFERENCE   9  (bases 1 to 4851)
  AUTHORS   Uchimura,K., Kadomatsu,K., Fan,Q.W., Muramatsu,H., Kurosawa,N.,
            Kaname,T., Yamamura,K., Fukuta,M., Habuchi,O. and Muramatsu,T.
  TITLE     Mouse chondroitin 6-sulfotransferase: molecular cloning,
            characterization and chromosomal mapping
  JOURNAL   Glycobiology 8 (5), 489-496 (1998)
   PUBMED   9597547
REFERENCE   10 (bases 1 to 4851)
  AUTHORS   Gupta,K., Anand,G., Yin,X., Grove,L. and Prochownik,E.V.
  TITLE     Mmip1: a novel leucine zipper protein that reverses the suppressive
            effects of Mad family members on c-myc
  JOURNAL   Oncogene 16 (9), 1149-1159 (1998)
   PUBMED   9528857
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK165878.1, AF047601.1 and AK005647.1.
            
            On Oct 6, 2007 this sequence version replaced NM_007790.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.49071.1,
                                           SRR1660825.48889.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-657               AK165878.1         2-658
            658-4114            AF047601.1         585-4041
            4115-4851           AK005647.1         1313-2049
FEATURES             Location/Qualifiers
     source          1..4851
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 48.13 cM"
     gene            1..4851
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /note="structural maintenance of chromosomes 3"
                     /db_xref="GeneID:13006"
                     /db_xref="MGI:MGI:1339795"
     exon            1..159
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..3798
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /note="mad member-interacting protein 1; structural
                     maintenace of chromosomes 3; chromosome segregation
                     protein SmcD; basement membrane-associated chondroitin
                     proteoglycan; SMC protein 3; chondroitin sulfate
                     proteoglycan 6"
                     /codon_start=1
                     /product="structural maintenance of chromosomes protein 3"
                     /protein_id="NP_031816.2"
                     /db_xref="CCDS:CCDS38025.1"
                     /db_xref="GeneID:13006"
                     /db_xref="MGI:MGI:1339795"
                     /translation="MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYA
                     IQFVLSDEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRRVI
                     GAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSQRLKLLR
                     EVAGTRVYDERKEESISLMKETEGKREKINELLKYIEERLHTLEEEKEELAQYQKWDK
                     MRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRE
                     LKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLL
                     EKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERD
                     KWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEE
                     LDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKREDLEKKQQLLRAATGKAILNG
                     IDSINKVLEHFRRKGINQHVQNGYHGIVMNNFECEPAFYTCVEVTAGNRLFYHIVDSD
                     EVSTKILMEFNKMNLPGEVTFLPLNKLDVRDTAYPETNDAIPMISKLRYNPRFDKAFK
                     HVFGKTLICRSMEVSTQLARAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDV
                     RKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMK
                     MLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVD
                     ALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETEGG
                     TVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDA
                     INHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQC
                     NTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEELDRGYKSIMELMNVLELRKYEAIQ
                     LTFKQVSKNFSEVFQKLVPGGKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVP
                     SVDQFTGVGIRVSFTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEID
                     QALDAQHRKAVSDMIMELAVHAQFITTTFRPELLESADKFYGVKFRNKVSHIDVITAE
                     MAKDFVEDDTTHG"
     exon            160..235
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            236..274
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            275..342
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            343..414
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            415..494
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            495..573
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            574..691
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            692..867
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            868..948
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1113
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1235
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1449
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1553
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..1653
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            1654..1814
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            1815..1956
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..2107
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2260
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            2261..2412
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            2413..2571
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            2572..2679
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..2788
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            2789..3036
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            3037..3249
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            3250..3441
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            3442..3619
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            3620..3726
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     exon            3727..4851
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4153..4158
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /note="hexamer: AATACA"
     polyA_site      4170
                     /gene="Smc3"
                     /gene_synonym="Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD"
                     /note="major polyA site"
ORIGIN      
        1 gccattttgt ttggccacag ggggagcgag cgggagcgag cggagcgctg tgaggagggg
       61 gctgtcttgc tcgtcttccg agcctgcggc cgcgctgctg cggtgctgag gcgacgcctt
      121 ccccctgccg aggggcgcgg agccatgtac atcaagcagg tgatcatcca gggcttccga
      181 agttaccgag accaaacaat tgtagatccc ttcagctcca aacataatgt catcgtgggc
      241 agaaatggct ctggaaaaag caacttcttt tatgcaatcc agtttgttct cagtgatgaa
      301 ttcagccatc ttcgtccaga gcagcgattg gctttgttgc atgagggtac aggtcctcgt
      361 gttatttctg cttttgtgga aatcattttt gacaattcgg acaaccggtt accaattgat
      421 aaagaggaag tttcacttcg aagagttatt ggtgccaaaa aggatcagta tttcctagat
      481 aagaagatgg tcacgaaaaa tgatgtgatg aatctccttg aaagtgctgg gttttccaga
      541 agtaatcctt attacattgt taaacaagga aagatcaacc aaatggcaac ggcaccagat
      601 tctcagagat taaagctgtt gagagaagta gctggtacta gagtgtatga tgaacggaaa
      661 gaagaaagca tctccctgat gaaagaaaca gagggcaaac gggaaaagat caatgagttg
      721 ttgaagtaca ttgaagagcg cctgcacact ctagaggagg agaaggagga gctggcccag
      781 tatcagaagt gggataagat gaggcgcgcc ctggagtaca ccatctacaa ccaggagctc
      841 aacgagacgc gcgctaagct cgacgagctt tctgctaagc gagaaacgag tggagagaaa
      901 tccagacaac taagggatgc ccagcaggat gcaagagaca aaatggagga tattgagcgc
      961 caggttagag aactgaaaac aaaaatttca gccatgaaag aagaaaaaga acagcttagt
     1021 gctgaaagac aagagcagat taagcaaagg accaagttgg agcttaaagc caaggattta
     1081 caagatgagc tggcgggcaa cagtgaacag cggaaacgtt tattaaaaga gaggcagaag
     1141 ctgcttgaaa aaatagaaga aaagcagaaa gaactggcag aaacagaacc taaattcaac
     1201 agcgtaaaag aaaaagaaga gcgaggaatt gcgaggttgg ctcaagctac acaggaaaga
     1261 actgatcttt atgcaaagca gggtcgagga agccagttta cgtcaaaaga agaaagggat
     1321 aaatggatta aaaaggaact gaagtcttta gatcaggcaa ttaatgataa gaaaagacag
     1381 attgctgcta ttcacaagga tttggaggat accgaggcaa ataaagagaa aaatctggag
     1441 caatataata aattggatca ggatctcaat gaagtcaaag ctcgagttga agaactggac
     1501 agaaaatatt atgaagtaaa aaataagaaa gatgaactac aaagtgaaag aaattacttg
     1561 tggagagagg agaatgcaga acaacaagca cttgctgcta aaagagaaga ccttgagaag
     1621 aagcagcaac ttcttagagc ggcaacagga aaggccattt taaatggaat agatagcatt
     1681 aacaaagtgc tagaacattt tcggcgaaaa ggtataaacc agcatgttca aaatggctac
     1741 catggcatcg taatgaataa ctttgagtgt gaaccagctt tctatacttg tgtggaagtc
     1801 actgctggta acaggttatt ttatcacatt gttgattcag atgaagtcag cacgaaaatt
     1861 ttaatggagt tcaataaaat gaatcttcct ggagaggtga ctttcctgcc tcttaacaag
     1921 ttagatgtga gagatactgc ctatcctgaa actaacgatg ctattcctat gatcagtaag
     1981 ctgaggtaca atcccagatt tgacaaagct ttcaaacatg tatttggaaa gacactcatc
     2041 tgtcggagca tggaagtttc aactcagctg gcccgggcct tcactatgga ctgtattact
     2101 ttggaaggtg atcaagtcag ccatcgaggt gctctgactg gaggttatta cgacacaaga
     2161 aagtctcgac ttgagttaca gaaagacgtt aggaaggcag aggaggagct gggtgagctg
     2221 gaggctaagc tcaatgaaaa cctacgcagg aacattgaaa ggattaataa tgaaattgac
     2281 cagttgatga accaaatgca gcagatagag acccaacaaa gaaaatttaa agcatccaga
     2341 gatagcatat tatcagagat gaagatgcta aaagagaaga gacagcaatc agaaaagacc
     2401 ttcatgccaa agcaacgtag cttacaaagc ttggaggcaa gtctgcatgc tatggagtcc
     2461 accagagagt cactgaaagc ggagctagga acggatttgc tttctcaact cagtctggaa
     2521 gatcagaaaa gagtcgacgc tctgaatgat gaaatccgtc agctgcagca ggaaaacaga
     2581 cagctgctaa atgaaagaat taaactagaa ggcattatta ctcgagtaga gacttacctg
     2641 aatgagaatc tgaggaaacg cttggaccaa gtagaacagg aacttaatga actgagagag
     2701 acagaaggtg gtactgttct tactgccaca acatcagaac ttgaagctat taataaaaga
     2761 gtaaaagata ctatggcaag atcagaagat ttggacaatt ccattgacaa aacagaagct
     2821 ggaattaaag agctccagaa aagtatggag cgctggaaaa atatggagaa agaacacatg
     2881 gatgccataa atcatgatac taaagagctg gagaagatga ccaaccggca aggcatgctg
     2941 ttgaagaaga aggaggagtg tatgaagaag atccgggagc tggggtccct cccccaggaa
     3001 gcgtttgaga agtaccagac actgagcctg aagcagttgt ttcgaaaact ggagcaatgc
     3061 aacacagagt taaagaagta cagccacgtg aacaaaaagg ctctagatca gtttgtgaat
     3121 ttctctgagc agaaggaaaa gctgataaag cggcaagagg aattggatag aggctacaaa
     3181 tcaatcatgg aattgatgaa tgtacttgaa cttagaaaat atgaagctat tcagttaact
     3241 ttcaaacagg tatctaagaa cttcagtgaa gttttccaga agttggtacc tggtggcaaa
     3301 gcgactttgg tgatgaagaa aggagatgtg gagggcagcc agtctcagga cgaaggagaa
     3361 gggagtggcg agagtgagcg gggctctggg tcacagagca gtgttccatc agttgaccag
     3421 ttcacaggag ttgggatcag ggtgtcattt acagggaagc aaggggagat gagagaaatg
     3481 cagcagctct caggaggaca gaaatctctg gtagcccttg ctctcatctt tgccattcag
     3541 aaatgcgacc ctgctccttt ttacctgttt gatgagatcg accaagcttt ggatgctcag
     3601 cacagaaaag ccgtgtcaga tatgattatg gagctagccg tgcatgccca gtttattacc
     3661 actactttca ggcctgaact gcttgagtca gctgacaaat tctatggtgt aaagttcaga
     3721 aataaggtta gtcacattga tgtgatcaca gcagagatgg ccaaagattt tgtagaagac
     3781 gataccacgc atggttaact gaaggataat gcttgctgtc ttggaagatg tgtataataa
     3841 tgtggtccat acccagaact gtaaatttta aaactaaata tttggttatt attgagtttt
     3901 tagatttaga gtacacagtc cttttatact tgtctttgta ttttataagc tcccctgtaa
     3961 tgttacattt ctacatatag ctgaggaatt ttatttccta tgcggctttt tgtaaagtgt
     4021 cctcctattt taaatctttt gagatattct aaatattctt cccaattatt ttatagcttc
     4081 tattaaataa ttggtttgtg actaacttag tgtaaatgtg gcctttggtc tttgcaatgg
     4141 ttagaaacat taaatacata ttttgcataa gaaagtgttg ctttcagtta ctagaggact
     4201 aaaaagtaca gttctgtatt ctgttaatta ctcactgggt tttcaattct ggccatggtt
     4261 tataatctgt tttgaatttt ccaaagtgtc acagtgctaa agtctttcct tgggctagcc
     4321 caggcaatct taaggaagtg ctgtcccaac caccttgctt aaaagttcct caggtggtgc
     4381 agagtttgag gactgctaac agccctgctt ttactcagat gagagtcctt tgaacattct
     4441 tttctgttta catcatacac acaggtattg gatctcatgg gtctgattat agatgtttgt
     4501 gagccgccac aggaccactg gaagaacagc cagtgctcct aactgctgag ccatctccct
     4561 agaccccttc caacattgtc aatttaatat gactctctta accaaagcca tagatttaga
     4621 aaagcagttt tatgtgggat tcagatgctg ataccaaatg tgagccatgc ggtttccttg
     4681 ttggttaagc caggcagttc caggagacac ttaatacata ctgtgttcag ttctaggacc
     4741 acaaaaaaag taaggctttg ttgctgaggc cacattcacc atgaggtctt tggggcattt
     4801 tgtttgtttt taaatggttt tgccattcat gtgccataaa atttacccat g
//
