LOCUS       NM_031842               3142 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus SWI/SNF related BAF chromatin remodeling complex
            subunit D1 (Smarcd1), transcript variant 1, mRNA.
ACCESSION   NM_031842
VERSION     NM_031842.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3142)
  AUTHORS   Zhao,Y., Liu,Y., Zhao,G., Lu,H., Liu,Y., Xue,C., Chang,Z., Liu,H.,
            Deng,Y., Liang,W., Wang,H., Rom,O., Garcia-Barrio,M.T., Zhu,T.,
            Guo,Y., Chang,L., Lin,J., Chen,Y.E. and Zhang,J.
  TITLE     Myeloid BAF60a deficiency alters metabolic homeostasis and
            exacerbates atherosclerosis
  JOURNAL   Cell Rep 42 (10), 113171 (2023)
   PUBMED   37768825
REFERENCE   2  (bases 1 to 3142)
  AUTHORS   Zhao,Y., Zhao,G., Chang,Z., Zhu,T., Zhao,Y., Lu,H., Xue,C.,
            Saunders,T.L., Guo,Y., Chang,L., Chen,Y.E. and Zhang,J.
  TITLE     Generating endogenous Myh11-driven Cre mice for sex-independent
            gene deletion in smooth muscle cells
  JOURNAL   JCI Insight 8 (14), e171661 (2023)
   PUBMED   37289544
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3142)
  AUTHORS   Nguyen,H., Sokpor,G., Parichha,A., Pham,L., Saikhedkar,N., Xie,Y.,
            Ulmke,P.A., Rosenbusch,J., Pirouz,M., Behr,R., Stoykova,A.,
            Brand-Saberi,B., Nguyen,H.P., Staiger,J.F., Tole,S. and Tuoc,T.
  TITLE     BAF (mSWI/SNF) complex regulates mediolateral cortical patterning
            in the developing forebrain
  JOURNAL   Front Cell Dev Biol 10, 1011109 (2022)
   PUBMED   36263009
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3142)
  AUTHORS   Kong,Q., Zou,J., Zhang,Z., Pan,R., Zhang,Z.Y., Han,S., Xu,Y.,
            Gao,Y. and Meng,Z.X.
  TITLE     BAF60a Deficiency in Macrophage Promotes Diet-Induced Obesity and
            Metabolic Inflammation
  JOURNAL   Diabetes 71 (10), 2136-2152 (2022)
   PUBMED   35822944
  REMARK    GeneRIF: BAF60a Deficiency in Macrophage Promotes Diet-Induced
            Obesity and Metabolic Inflammation.
REFERENCE   5  (bases 1 to 3142)
  AUTHORS   El-Saafin,F., Bergamasco,M.I., Chen,Y., May,R.E., Esakky,P.,
            Hediyeh-Zadeh,S., Dixon,M., Wilcox,S., Davis,M.J., Strasser,A.,
            Smyth,G.K., Thomas,T. and Voss,A.K.
  TITLE     Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic
            neuronal cell death
  JOURNAL   Cell Death Differ 29 (5), 1013-1027 (2022)
   PUBMED   35361962
REFERENCE   6  (bases 1 to 3142)
  AUTHORS   Phelan,M.L., Sif,S., Narlikar,G.J. and Kingston,R.E.
  TITLE     Reconstitution of a core chromatin remodeling complex from SWI/SNF
            subunits
  JOURNAL   Mol Cell 3 (2), 247-253 (1999)
   PUBMED   10078207
REFERENCE   7  (bases 1 to 3142)
  AUTHORS   Reyes,J.C., Muchardt,C. and Yaniv,M.
  TITLE     Components of the human SWI/SNF complex are enriched in active
            chromatin and are associated with the nuclear matrix
  JOURNAL   J Cell Biol 137 (2), 263-274 (1997)
   PUBMED   9128241
REFERENCE   8  (bases 1 to 3142)
  AUTHORS   Wang,W., Cote,J., Xue,Y., Zhou,S., Khavari,P.A., Biggar,S.R.,
            Muchardt,C., Kalpana,G.V., Goff,S.P., Yaniv,M., Workman,J.L. and
            Crabtree,G.R.
  TITLE     Purification and biochemical heterogeneity of the mammalian SWI-SNF
            complex
  JOURNAL   EMBO J 15 (19), 5370-5382 (1996)
   PUBMED   8895581
REFERENCE   9  (bases 1 to 3142)
  AUTHORS   Wang,W., Xue,Y., Zhou,S., Kuo,A., Cairns,B.R. and Crabtree,G.R.
  TITLE     Diversity and specialization of mammalian SWI/SNF complexes
  JOURNAL   Genes Dev 10 (17), 2117-2130 (1996)
   PUBMED   8804307
REFERENCE   10 (bases 1 to 3142)
  AUTHORS   Johnston,L.A., Kotarski,M.A., Jerry,D.J. and Kozak,L.P.
  TITLE     An ubiquitously expressed gene 3.5 kilobases upstream of the
            glycerol-3-phosphate dehydrogenase gene in mice
  JOURNAL   Mol Cell Biol 9 (3), 935-945 (1989)
   PUBMED   2725507
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134548.5.
            
            On Sep 13, 2022 this sequence version replaced NM_031842.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059921.1, U66620.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-205               AC134548.5         34566-34770
            206-393             AC134548.5         35378-35565
            394-436             AC134548.5         35863-35905
            437-559             AC134548.5         36010-36132
            560-682             AC134548.5         36603-36725
            683-799             AC134548.5         37899-38015
            800-901             AC134548.5         39583-39684
            902-1063            AC134548.5         39912-40073
            1064-1161           AC134548.5         40157-40254
            1162-1297           AC134548.5         41553-41688
            1298-1420           AC134548.5         43365-43487
            1421-1522           AC134548.5         44431-44532
            1523-3142           AC134548.5         44644-46263
FEATURES             Location/Qualifiers
     source          1..3142
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 56.13 cM"
     gene            1..3142
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /note="SWI/SNF related BAF chromatin remodeling complex
                     subunit D1"
                     /db_xref="GeneID:83797"
                     /db_xref="MGI:MGI:1933623"
     exon            1..205
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1576
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     SWI/SNF-related matrix-associated actin-dependent
                     regulator of chromatin subfamily D member 1; SWI/SNF
                     related, matrix associated, actin dependent regulator of
                     chromatin, subfamily d, member 1; BRG1-associated factor
                     60A; SWI/SNF complex 60 kDa subunit; 60 kDa
                     BRG-1/Brm-associated factor subunit A"
                     /codon_start=1
                     /product="SWI/SNF-related matrix-associated
                     actin-dependent regulator of chromatin subfamily D member
                     1 isoform 1"
                     /protein_id="NP_114030.2"
                     /db_xref="CCDS:CCDS37204.1"
                     /db_xref="GeneID:83797"
                     /db_xref="MGI:MGI:1933623"
                     /translation="MAARAGFQSVAPSGGAGASGGAGVAAALGPGGTPGPPVRMGPAP
                     GQGLYRSPMPGAAYPRPGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKR
                     PAPQQIQQVQQQAVQNRNHNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQT
                     IMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLED
                     AALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPG
                     DVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHER
                     EFVLCDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACYDI
                     DVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQG
                     FINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQ
                     ALGIRNT"
     exon            206..393
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            394..436
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            437..559
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            560..682
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            683..799
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            800..901
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1063
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1161
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1297
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1420
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1522
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..3142
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3121..3126
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /note="hexamer: AATAAA"
     polyA_site      3142
                     /gene="Smarcd1"
                     /gene_synonym="Baf60a; D15Kz1"
                     /note="major polyA site"
ORIGIN      
        1 gtgcagctgc agcggcggct ccgggaagat ggcggcccgg gcgggtttcc agtctgtggc
       61 tccgagcggc ggcgcgggag cctcaggagg agcgggcgtg gcggctgctc tgggcccggg
      121 cggaactccc gggcctcccg tgcgaatggg cccggcgccg ggtcaagggc tgtaccgctc
      181 tccgatgccc ggggcggcct atccgagacc aggtatgctg ccaggtagcc gaatgacacc
      241 tcagggacct tccatgggac ctcctggcta tggggggaac ccttcagtcc gacctggtct
      301 ggcccagtca gggatggacc agtcccgcaa gagacctgca cctcaacaga tccagcaggt
      361 ccagcagcag gcggtccaaa atcgaaatca caatgcaaag aaaaagaaga tggctgacaa
      421 aatcctacct caaaggattc gggaactggt cccagaatca caggcctaca tggatctcct
      481 ggcttttgaa aggaaactgg accagactat tatgaggaag cggctagata tccaggaggc
      541 cttgaaacgt cccatcaagc aaaaacggaa gctgcgaatt ttcatttcta acacgttcaa
      601 tccggctaag tcggacgcgg aggatgggga agggacggtg gcttcctggg agctccgggt
      661 agaaggccgg ctcctggagg acgcggcctt gtccaaatat gacgccacca agcaaaagag
      721 aaagttctct tcctttttta agtccttggt gatcgaactg gacaaagacc tctatggccc
      781 agacaaccat ctggtagaat ggcacaggac cgccactacc caggagaccg atggcttcca
      841 ggtgaagcgg ccaggagatg tgaatgtacg gtgtactgtc ctgctgatgc tggactacca
      901 gcccccccag tttaaattag accctcgcct ggctcggctc ttgggcatcc atacccagac
      961 acgtccagtg atcatccaag cactgtggca gtatattaaa acacacaagc tccaggaccc
     1021 tcacgagcga gagtttgttc tctgtgacaa gtacctccag cagatctttg aatctcagcg
     1081 gatgaagttc tcagagatcc ctcagcggct ccacgccttg cttatgccac cagagcccat
     1141 catcatcaat catgtcatca gtgtggaccc aaatgaccag aaaaagaccg cgtgctatga
     1201 cattgacgtg gaggtggatg acactctgaa gacccagatg aactctttcc tgttgtccac
     1261 tgccagccag caggagatcg ccactctaga caacaagatc catgagacga tagagaccat
     1321 caaccagctg aagacccagc gagagttcat gttgagcttt gcccgagacc ctcagggttt
     1381 catcaatgat tggcttcagt cccagtgcag ggacctcaag acgatgactg atgtggtggg
     1441 taacccggaa gaggagcgtc gtgctgagtt ctacttccag ccctgggctc aggaggctgt
     1501 gtgccgatac ttctactcca aggtgcagca gaggcggcaa gagttagagc aagccctggg
     1561 aatccgaaac acatagggcc tctgtggccc tagcctggct gcaccgattc cttgggccct
     1621 gtgctgcctg cctcagtgta cctgtcttgg tcttgcttga ggcattccag gggacttggc
     1681 ttcaggacag tgtcacaatg aagagggtgt cacatttctg tctcacagtc acctgttatc
     1741 ccgtcctgta ccccagtcgt cccccgtccc gtcgtgtccc cccctcaccc caccccgcct
     1801 cagctcctcc ccatcaggct cctgtgtgcc tctacctccc tatcctacat aggacctcta
     1861 gatagtgtta gagaaccaca gagtgggggc ctcctgaggt caggtggtct tgagggagac
     1921 cagctacact gatcctgccc ttgtcaggag acctaggcct tgggagctat ccctgtctga
     1981 gcctcaggcc tagggcagtc tgtaagctag ctgaccttgg ccctcccggt agcttgactt
     2041 cttccctccc ctccgcaggt tggggcagag gctcctttac ctctggcagt aaaggagcct
     2101 gggcttcact gagccccggg ttggtcccct gccctctgga cttaacctgc tgtctcagtg
     2161 tcctctgacc ccttaggggt ccatgtcagt attggagtgt gtgttgaatt gttgctccct
     2221 cccacacact cccgtagccg cccagtttag gatttcccta cacctgccct aacccacgct
     2281 tttgggttgg ggatcttgcc tttccttgtc attcccagca gagactgttc cttcctgctg
     2341 ttagaggagt ggcttgttta ttcactccac cctgccccct cctgtaaatg gagaaacagg
     2401 cctgaaatca aacgggtaaa gccctaggcc atccctgtct tcctgtccca tgtctgccca
     2461 gttgaatccc actggtggct tcccgggcac tgaggagtaa aagcgcctag ggctggagaa
     2521 taggtctgaa atgggtttgt gactccccac cccctgccct gccctcaaag cttcagaccc
     2581 ctcagggagc agcaggatgt gggatcgagg ccccttggga cagatgcttt gaatcttcca
     2641 gggaagcctc cgattcttcc aggtttgtca cccggagtta gcatgtccca ggctcgcaga
     2701 caacactgca gggtgggaga cagctgggca cagggggatt ctgttgagca tgggctctga
     2761 acccacagaa ctgacaaagc ccctgcttcc ccacccccac ctcaggctcc tgcgagcagt
     2821 gctcctgcac ccttcccagc ctgttctgta ctggggacag cagtcttctc cctgtcctcc
     2881 catgtcctat atccacccct ccccttggaa ggtcctcccc acagtgacac tggacagccc
     2941 tggggcagct gagccccagc ctggcttctg gctggaagcg cgatgaggag acttagcact
     3001 ccacagtgtc cctggtggta actgttctta ttaactgatt gtgttttgtt ttgttttgtt
     3061 ttgttttcat ggaccaaaat tttttttgta ctgtctcctt aactgatgtc acccagtttt
     3121 aataaaagac ttctaaagag ca
//
