LOCUS       NM_007958               4945 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus SNF2 related chromatin remodeling ATPase with DExD box
            1 (Smarcad1), transcript variant 1, mRNA.
ACCESSION   NM_007958 XM_132597
VERSION     NM_007958.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4945)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4945)
  AUTHORS   Sachs,P., Bergmaier,P., Treutwein,K. and Mermoud,J.E.
  TITLE     The Conserved Chromatin Remodeler SMARCAD1 Interacts with TFIIIC
            and Architectural Proteins in Human and Mouse
  JOURNAL   Genes (Basel) 14 (9), 1793 (2023)
   PUBMED   37761933
  REMARK    GeneRIF: The Conserved Chromatin Remodeler SMARCAD1 Interacts with
            TFIIIC and Architectural Proteins in Human and Mouse.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4945)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4945)
  AUTHORS   Niu,Q., Wang,W., Wei,Z., Byeon,B., Das,A.B., Chen,B.S. and Wu,W.H.
  TITLE     Role of the ATP-dependent chromatin remodeling enzyme
            Fun30/Smarcad1 in the regulation of mRNA splicing
  JOURNAL   Biochem Biophys Res Commun 526 (2), 453-458 (2020)
   PUBMED   32234239
  REMARK    GeneRIF: Role of the ATP-dependent chromatin remodeling enzyme
            Fun30/Smarcad1 in the regulation of mRNA splicing.
REFERENCE   5  (bases 1 to 4945)
  AUTHORS   Kazakevych,J., Denizot,J., Liebert,A., Portovedo,M., Mosavie,M.,
            Jain,P., Stellato,C., Fraser,C., Correa,R.O., Celestine,M.,
            Mattiuz,R., Okkenhaug,H., Miller,J.R., Vinolo,M.A.R., Veldhoen,M.
            and Varga-Weisz,P.
  TITLE     Smarcad1 mediates microbiota-induced inflammation in mouse and
            coordinates gene expression in the intestinal epithelium
  JOURNAL   Genome Biol 21 (1), 64 (2020)
   PUBMED   32160911
  REMARK    GeneRIF: Smarcad1 mediates microbiota-induced inflammation in mouse
            and coordinates gene expression in the intestinal epithelium.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4945)
  AUTHORS   Ben-Arie,N., McCall,A.E., Berkman,S., Eichele,G., Bellen,H.J. and
            Zoghbi,H.Y.
  TITLE     Evolutionary conservation of sequence and expression of the bHLH
            protein Atonal suggests a conserved role in neurogenesis
  JOURNAL   Hum Mol Genet 5 (9), 1207-1216 (1996)
   PUBMED   8872459
REFERENCE   7  (bases 1 to 4945)
  AUTHORS   Villeneuve,L., Jiang,X., Turmel,C., Kozak,C.A. and Jolicoeur,P.
  TITLE     Long-range mapping of Mis-2, a common provirus integration site
            identified in murine leukemia virus-induced thymomas and located
            160 kilobase pairs downstream of Myb
  JOURNAL   J Virol 67 (10), 5733-5739 (1993)
   PUBMED   8371338
REFERENCE   8  (bases 1 to 4945)
  AUTHORS   Schoor,M., Schuster-Gossler,K. and Gossler,A.
  TITLE     The Etl-1 gene encodes a nuclear protein differentially expressed
            during early mouse development
  JOURNAL   Dev Dyn 197 (3), 227-237 (1993)
   PUBMED   8219362
REFERENCE   9  (bases 1 to 4945)
  AUTHORS   Soininen,R., Schoor,M., Henseling,U., Tepe,C., Kisters-Woike,B.,
            Rossant,J. and Gossler,A.
  TITLE     The mouse Enhancer trap locus 1 (Etl-1): a novel mammalian gene
            related to Drosophila and yeast transcriptional regulator genes
  JOURNAL   Mech Dev 39 (1-2), 111-123 (1992)
   PUBMED   1489724
REFERENCE   10 (bases 1 to 4945)
  AUTHORS   O'Kane,C.J. and Gehring,W.J.
  TITLE     Detection in situ of genomic regulatory elements in Drosophila
  JOURNAL   Proc Natl Acad Sci U S A 84 (24), 9123-9127 (1987)
   PUBMED   2827169
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138622.4 and AC143330.4.
            
            On Jul 22, 2022 this sequence version replaced NM_007958.2.
            
            Transcript Variant: This variant (1) encodes the longest protein
            (isoform 1).  Variants 1 and 5 encode the same protein (isoform 1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122454.1, X69942.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-141               AC138622.4         180348-180488
            142-381             AC138622.4         180733-180972
            382-559             AC138622.4         190147-190324
            560-725             AC138622.4         193930-194095
            726-792             AC143330.4         190882-190948       c
            793-884             AC143330.4         181876-181967       c
            885-986             AC143330.4         176928-177029       c
            987-1068            AC143330.4         175739-175820       c
            1069-1457           AC143330.4         173864-174252       c
            1458-1657           AC143330.4         165011-165210       c
            1658-1748           AC143330.4         158828-158918       c
            1749-1848           AC143330.4         156420-156519       c
            1849-1908           AC143330.4         154824-154883       c
            1909-1984           AC143330.4         154649-154724       c
            1985-2120           AC143330.4         152848-152983       c
            2121-2258           AC143330.4         152187-152324       c
            2259-2354           AC143330.4         150309-150404       c
            2355-2472           AC143330.4         150101-150218       c
            2473-2594           AC143330.4         149627-149748       c
            2595-2783           AC143330.4         141051-141239       c
            2784-2902           AC143330.4         140244-140362       c
            2903-3085           AC143330.4         138462-138644       c
            3086-3195           AC143330.4         137129-137238       c
            3196-4945           AC143330.4         132964-134713       c
FEATURES             Location/Qualifiers
     source          1..4945
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 30.11 cM"
     gene            1..4945
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /note="SNF2 related chromatin remodeling ATPase with DExD
                     box 1"
                     /db_xref="GeneID:13990"
                     /db_xref="MGI:MGI:95453"
     exon            1..141
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            142..381
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..3257
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /EC_number="3.6.4.12"
                     /note="isoform 1 is encoded by transcript variant 1;
                     SWI/SNF-related, matrix-associated actin-dependent
                     regulator of chromatin, subfamily a, containing DEAD/H box
                     1; enhancer trap locus homolog 1; ATP-dependent helicase
                     SMARCAD1; enhancer trap locus 1"
                     /codon_start=1
                     /product="SWI/SNF-related matrix-associated
                     actin-dependent regulator of chromatin subfamily A
                     containing DEAD/H box 1 isoform 1"
                     /protein_id="NP_031984.1"
                     /db_xref="CCDS:CCDS20204.1"
                     /db_xref="GeneID:13990"
                     /db_xref="MGI:MGI:95453"
                     /translation="MNLFNLDRFRFEKRSKIEEAPEAAPQPSQARPSSPISLSAEEEN
                     AEGEGSRANTPDSDVTEKTEDSSVPEPPDNERKASLSCFQNQRAIQEYIDLSSDTEDV
                     SPNCSSTVQEKKFSKDTVIIVSEPSEDEESHDLPSVTRRNDSSELEDLSELEDLKDAK
                     LQTLKELFPQRSDSDLLKLIESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEEDDV
                     NDDQSVKQPRGDRGEESNESAEASSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEW
                     MYTEALESLKVFAEDQDVQCASQSEVTNGKEVARNQNYSKNATKIKMKQKISVKPQNG
                     FNKKRKKNVFNPKKAVEDSEYDSGSDAGSSLDEDYSSCEEVMEDGYKGKILHFLQVSS
                     IAELTLIPKCSQKKAQKITELRPFNNWEALFTKMSKINGLSEDLIWNCKTVIQERDVV
                     IRLMNKCEDISNKLTKQVTMLTGNGGGWNREQPSLLNQSLSLKPYQKVGLNWLALVHK
                     HGLNGILADEMGLGKTIQAIAFLAYLFQEGNKGPHLIVVPASTIDNWLREVNLWCPSL
                     NVLCYYGSQEERKQIRFNIHNKYEDYNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDE
                     GHMLKNMGSIRYQHLMTINARNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIR
                     RMFSSKTKPADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKLLPPKKDRIELCAMSE
                     KQEQLYSGLFNRLKKSINNLEKNTEMCNVMMQLRKMANHPLLHRQYYTPEKLKEMSQL
                     MLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYQHINSYQLDMDLILDSGKFRALGC
                     ILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTD
                     MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKL
                     ISQGTIEESMLKINQQKLKLEQDMTTVDEADEGSMPADIATLLKTSMGL"
     exon            382..559
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            560..725
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            726..792
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            793..884
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            885..986
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1068
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1457
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1657
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1748
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1848
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..1908
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..1984
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2120
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            2121..2258
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            2259..2354
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            2355..2472
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2594
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            2595..2783
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            2784..2902
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            2903..3085
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..3195
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     exon            3196..4945
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4473..4478
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /note="hexamer: AATAAA"
     polyA_site      4493
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /note="major polyA site"
     regulatory      4922..4927
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /note="hexamer: AATAAA"
     polyA_site      4945
                     /gene="Smarcad1"
                     /gene_synonym="D6Pas1; etl-1; Etl1; mKIAA1122"
                     /note="major polyA site"
ORIGIN      
        1 acttccgggc ggcgcgccgc tcccgcttcg gccctttgtg ttcccgcggc ggaggctcgg
       61 gcctcgcggg ctttgtggag gcggcgggcg ctcggtgcgg gctgcgtggc gggaaggcgg
      121 gcgcgcacct ctgcggcccg gctagttcat tgaaagctgt cagccccctc agggtggtgg
      181 ttcctcccaa tatgaatctt ttcaacttgg accgttttcg ctttgagaaa aggagtaaga
      241 ttgaggaagc acccgaagca gcccctcagc cctcccaggc ccgtccttcg tcaccaattt
      301 ctcttagtgc tgaagaggag aatgctgaag gggaaggtag cagggcaaac accccagact
      361 cagatgtaac tgagaaaaca gaagattcta gtgttccaga accgccagac aatgaaagaa
      421 aagcaagttt atcatgtttc caaaatcaaa gagcaataca ggaatatatt gatttatcat
      481 ctgatactga agatgtttct ccaaattgtt ccagtacagt tcaagagaaa aaattcagca
      541 aagacacagt gattatagtt tcagagccat ctgaagatga agaatcccat gaccttcctt
      601 ctgttacacg aagaaatgac agttcagaac tggaagacct ttcagaattg gaagatctta
      661 aagatgctaa gcttcagaca ttgaaggaac tgtttccaca aagaagtgac agtgatcttc
      721 taaagttgat tgaatcaaca agcactatgg atggagccat tgctgctgcc ttgctgatgt
      781 ttggtgatgc aggtggtgga cccaggaaaa ggaaattatc ttcttcttct gaggaggatg
      841 acgttaatga tgatcagtct gtaaaacagc cgcgagggga ccgtggagaa gaatcaaatg
      901 agtctgcaga agccagcagc aactgggaaa agcaagaaag tattgtgttg aaattgcaaa
      961 aggaatttcc aaattttgat aaacaggaat taagagaagt gcttaaggag catgagtgga
     1021 tgtacacaga agccttggag tctctgaaag tgtttgcgga agatcaagac gtgcagtgtg
     1081 cttcacaaag tgaagttaca aatggaaaag aagttgcaag gaatcaaaat tattctaaaa
     1141 atgcaactaa aataaaaatg aaacagaaaa tttccgtgaa accacaaaat ggctttaaca
     1201 agaaacgtaa gaaaaatgta tttaatccta agaaagccgt agaggactct gagtacgatt
     1261 caggttctga tgctgggagc tcactggatg aggactatag cagttgtgaa gaagtgatgg
     1321 aggacggcta taaaggcaaa attcttcatt tccttcaagt ttcttcaatt gctgaactga
     1381 ctttgattcc taagtgttct cagaaaaagg ctcagaaaat aacagaactc cggcccttta
     1441 ataattggga agctctgttt acaaagatgt ctaaaatcaa tggcctatct gaagatttga
     1501 tatggaattg caaaacggta attcaagaaa gggacgtagt tataagactt atgaacaaat
     1561 gtgaggacat ttcaaataaa ctgaccaaac aagttacgat gctcaccggg aatggaggcg
     1621 gatggaacag agaacagccc tcccttctaa accaaagttt gtcactcaag ccctatcaga
     1681 aggttgggtt gaactggctg gcgttggtgc ataagcatgg acttaatggc attctggcag
     1741 acgaaatggg cctaggaaaa accattcaag ccattgcatt cctggcatac ctctttcaag
     1801 agggtaataa agggcctcat ttgattgttg ttccagcctc caccatagat aactggttaa
     1861 gagaagttaa cttatggtgc cccagtttaa atgtgctctg ttactatggt tctcaagaag
     1921 agcgtaagca aattagattc aacatccata ataagtatga ggattacaat gtaattgtta
     1981 caacgtataa ttgtgcaatc agcagctctg atgaccgcag tctctttcga cgactgaaac
     2041 tgaattatgc aatttttgat gaaggccata tgctgaagaa tatgggctct atccgctatc
     2101 aacatctaat gacaattaat gcacgtaacc gtttattgct cacaggcaca cctgtgcaga
     2161 ataatctgct agaactcatg tcattgttga attttgttat gccacacatg tttagcagta
     2221 gcaccagtga aatccgaagg atgttttctt ctaaaacgaa accagcagac gagcagagta
     2281 tatacgaaaa ggagagaata gcccacgcga agcaaatcat taagcccttc atcctcagga
     2341 gagtgaagga ggaggttctt aagctcctgc ctcccaagaa ggatcggatt gagctatgtg
     2401 cgatgtcaga gaagcaggag cagctctact cgggcctctt caacagattg aaaaagtcta
     2461 tcaacaacct ggaaaaaaac acagagatgt gcaatgtcat gatgcaattg agaaaaatgg
     2521 ccaatcaccc tttactacac cgccagtatt acacacctga gaaactgaag gagatgtctc
     2581 agctaatgct gaaggaacct acgcactgtg aggccaaccc tgacctgatc tttgaagaca
     2641 tggaagttat gacagatttt gaactacatg tactttgtaa acagtatcaa cacattaata
     2701 gttaccagtt agacatggat ttaattttag attctgggaa attccgagcc ttaggatgca
     2761 tcttgtctga gttgaaacag aagggtgata gagttgtatt attcagccag tttaccatga
     2821 tgctggatat actagaggtt ctcttaaagc atcatcaaca taggtacctc cgattagatg
     2881 gaaagactca gatttctgaa aggattcatc taattgatga gtttaataca gatatggata
     2941 tctttgtatt tctcttgtca actaaagctg gtggactagg aataaatctt acttcagcaa
     3001 atgttgttat acttcacgac attgattgca atccatacaa tgacaaacaa gcagaagaca
     3061 ggtgccatag agttggtcag actaaagaag tattagttat taaattaata agccaaggaa
     3121 ctattgaaga gtccatgcta aaaattaacc aacaaaagtt gaaactagag caagacatga
     3181 ccacagtaga tgaagctgat gaaggaagta tgccagcaga tatagccaca ttactaaaaa
     3241 catcaatggg cctgtgaagg agagcgcgga attcctgatt gatgaggaca tatcaacttg
     3301 gtgcattcaa ggacattcac atcacggtga ccatggggtt tctgagcatt tgtaattttt
     3361 tataatttca tgttgcattt cacatagtat ggacaacttt ttgccactaa ctggattctc
     3421 cagatcctca catcctgaaa atgttgacta atcatttttc aaagcagttt tctgaatggg
     3481 gttagttggt gattgtttgt aacaaatatg ctaatgcttt agaaatgtca gtatttttgt
     3541 aattatttct acctccagat atatatacat atatatatat atatatagtg tctttcactg
     3601 gataatgtgt gtagatttac atgtgcctta tttgacaatg tttatgtctt gttttgcttg
     3661 tctgatttga agtttttatt atgttaaaga atgcagctgt ataggttgtt cagtcttcat
     3721 tttattgcta tttgatgcag atgttcacca atgtcagtaa gaactcagcc tgaatcacaa
     3781 ggtggcattc catccactaa tgtccccagg tcctcttctt cctcctgtta gaacacattt
     3841 gtttggctaa gcactaagtt gttttccagt gagtaggaac tgaagccttt ctcctgctct
     3901 ggggggtcag ttccttcttt cattttctta ttgcacctct ggctcattaa ctctgccttc
     3961 gcttgtgtgt gttgctatca gcttcctctc ccgcttttgc ttctcttaac cattgcccag
     4021 tcacttctgc tccagttttc tcttacacat ttccttctgc tgaatcacca agatcagcag
     4081 atgttggtgg catatttcta gtccagcaga acagattaac ttaaagatac tttcacttca
     4141 aaggaaactg gatgtgactt cataccaagg taatgctaga tactgcatga aaataggtca
     4201 ttaactttaa attcttaaca aaatataatt taccagttcc caggatttcc aatacagaac
     4261 cacctgaaga gaagccattg ttcaattcca gttcagtgtg ggtgacaaag tgaaatttag
     4321 aagtaaaatt gtctatttgg tatttcagtc tttattaact tttcatttaa attttgcctg
     4381 tcagtctata ttgctgtttt tattatacat cagattcttt gtataacttg tgagttttat
     4441 gtgctttgtt ttataatgta aatatcatta taaataaact tatttataaa tgagagattt
     4501 gttaattatt gtagctcata cttttcaaga cacccccagt gctgaggtgc taggtaaaca
     4561 cttagatggg tgacacaatc ctacagtgct attttttttt caggtatctg agactctgaa
     4621 ctcctgactc agtagattta atattgaaga tatatgactg tatcaaattt atctccccac
     4681 tacggggctg ccaggaattt gcaggtgtta atgctacctc cttgtgatca cagtacccag
     4741 gtcgcttagt caagttgttg gaaattgtac cttttaaacc cacagtgaat ttcccttaac
     4801 ttttctgtgt gaaatgtgtc tcccacagta ggctcattgg ttgtggtgtt gttatatctg
     4861 aattttttct aatgaaatgt agttggattc tccctgtaat attttattat gtcttgggtt
     4921 taataaaaat atttgtgatc attaa
//
