LOCUS       NM_201530                918 bp    mRNA    linear   ROD 16-NOV-2021
DEFINITION  Mus musculus Sycp3 like Y-linked (Sly), mRNA.
ACCESSION   NM_201530 XM_006536368 XM_356420 XM_487005
VERSION     NM_201530.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Moretti C, Blanco M, Ialy-Radio C, Serrentino ME, Gobe C, Friedman
            R, Battail C, Leduc M, Ward MA, Vaiman D, Tores F and Cocquet J.
  TITLE     Battle of the Sex Chromosomes: Competition between X and Y
            Chromosome-Encoded Proteins for Partner Interaction and Chromatin
            Occupancy Drives Multicopy Gene Expression and Evolution in Muroid
            Rodents
  JOURNAL   Mol Biol Evol 37 (12), 3453-3468 (2020)
   PUBMED   32658962
  REMARK    GeneRIF: Battle of the Sex Chromosomes: Competition between X and Y
            Chromosome-Encoded Proteins for Partner Interaction and Chromatin
            Occupancy Drives Multicopy Gene Expression and Evolution in Muroid
            Rodents.
REFERENCE   2  (bases 1 to 918)
  AUTHORS   Moretti C, Serrentino ME, Ialy-Radio C, Delessard M, Soboleva TA,
            Tores F, Leduc M, Nitschke P, Drevet JR, Tremethick DJ, Vaiman D,
            Kocer A and Cocquet J.
  TITLE     SLY regulates genes involved in chromatin remodeling and interacts
            with TBL1XR1 during sperm differentiation
  JOURNAL   Cell Death Differ 24 (6), 1029-1044 (2017)
   PUBMED   28475176
  REMARK    GeneRIF: SLY is a regulator of sperm chromatin remodeling.
            SMRT/N-CoR repressor complex is involved in gene regulation during
            sperm differentiation since members of this complex, in particular
            TBL1XR1, interact with SLY in postmeiotic male germ cells.
REFERENCE   3  (bases 1 to 918)
  AUTHORS   Comptour A, Moretti C, Serrentino ME, Auer J, Ialy-Radio C, Ward
            MA, Toure A, Vaiman D and Cocquet J.
  TITLE     SSTY proteins co-localize with the post-meiotic sex chromatin and
            interact with regulators of its expression
  JOURNAL   FEBS J 281 (6), 1571-1584 (2014)
   PUBMED   24456183
REFERENCE   4  (bases 1 to 918)
  AUTHORS   Riel JM, Yamauchi Y, Sugawara A, Li HY, Ruthig V, Stoytcheva Z,
            Ellis PJ, Cocquet J and Ward MA.
  TITLE     Deficiency of the multi-copy mouse Y gene Sly causes sperm DNA
            damage and abnormal chromatin packaging
  JOURNAL   J Cell Sci 126 (Pt 3), 803-813 (2013)
   PUBMED   23178944
  REMARK    GeneRIF: deficiency is responsible for the sperm DNA
            damage/chromatin packaging
REFERENCE   5  (bases 1 to 918)
  AUTHORS   Cocquet J, Ellis PJ, Mahadevaiah SK, Affara NA, Vaiman D and
            Burgoyne PS.
  TITLE     A genetic basis for a postmeiotic X versus Y chromosome
            intragenomic conflict in the mouse
  JOURNAL   PLoS Genet 8 (9), e1002900 (2012)
   PUBMED   23028340
  REMARK    Erratum:[PLoS Genet. 2019 Jul 22;15(7):e1008290. PMID: 31329581]
REFERENCE   6  (bases 1 to 918)
  AUTHORS   Yao CJ, Xu WJ, Gong XL, Zhou Y, Yan ZQ, Zhu ZJ, Wang ZX, Li QL, Guo
            XB, Wang LY, Ma D and Qiao ZD.
  TITLE     The role of Dby mRNA in early development of male mouse zygotes
  JOURNAL   Asian J Androl 12 (4), 567-577 (2010)
   PUBMED   20543856
REFERENCE   7  (bases 1 to 918)
  AUTHORS   Cocquet J, Ellis PJ, Yamauchi Y, Mahadevaiah SK, Affara NA, Ward MA
            and Burgoyne PS.
  TITLE     The multicopy gene Sly represses the sex chromosomes in the male
            mouse germline after meiosis
  JOURNAL   PLoS Biol 7 (11), e1000244 (2009)
   PUBMED   19918361
  REMARK    GeneRIF: expansion of sex-linked spermatid-expressed genes in mouse
            is a consequence of the enhancement of postmeiotic sex chromatin
            repression that accompanies Sly amplification
REFERENCE   8  (bases 1 to 918)
  AUTHORS   Yamauchi Y, Riel JM, Wong SJ, Ojarikre OA, Burgoyne PS and Ward MA.
  TITLE     Live offspring from mice lacking the Y chromosome long arm gene
            complement
  JOURNAL   Biol Reprod 81 (2), 353-361 (2009)
   PUBMED   19420387
REFERENCE   9  (bases 1 to 918)
  AUTHORS   Reynard LN, Cocquet J and Burgoyne PS.
  TITLE     The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an
            abundant spermatid protein that interacts with a histone
            acetyltransferase and an acrosomal protein
  JOURNAL   Biol Reprod 81 (2), 250-257 (2009)
   PUBMED   19176879
  REMARK    GeneRIF: SLY1 interacts with acrosomal protein DKKL1, histone
            acetyltransferase KAT5 & microtubule-associated protein APPBP2;
            data suggest SLY1 may be involved in spermiogenesis processes,
            including control of gene expression & acrosome development or
            function
REFERENCE   10 (bases 1 to 918)
  AUTHORS   Toure A, Clemente EJ, Ellis P, Mahadevaiah SK, Ojarikre OA, Ball
            PA, Reynard L, Loveland KL, Burgoyne PS and Affara NA.
  TITLE     Identification of novel Y chromosome encoded transcripts by testis
            transcriptome analysis of mice with deletions of the Y chromosome
            long arm
  JOURNAL   Genome Biol 6 (12), R102 (2005)
   PUBMED   16356265
  REMARK    Erratum:[Genome Biol. 2019 Aug 9;20(1):160. PMID: 31399122]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC049626.1 and AC145567.5.
            
            On or before Jan 5, 2014 this sequence version replaced
            XM_006536368.1, NM_201530.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-913               BC049626.1         1-913
            914-918             AC145567.5         207157-207161       c
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="Y"
                     /map="Y"
     gene            1..918
                     /gene="Sly"
                     /note="Sycp3 like Y-linked"
                     /db_xref="GeneID:382301"
                     /db_xref="MGI:MGI:2687328"
     exon            1..44
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            45..176
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..727
                     /gene="Sly"
                     /codon_start=1
                     /product="Sycp3 like Y-linked"
                     /protein_id="NP_963288.2"
                     /db_xref="CCDS:CCDS81234.1"
                     /db_xref="GeneID:382301"
                     /db_xref="MGI:MGI:2687328"
                     /translation="MRRMALKKLKVIPKEGYLLLLDFDDEDDDIKVSEEALSEVKSPA
                     FDKNENISPQAEADEDMGDEVDSMLDKSEVNNPAIGKDENISPQVKGDEDMGHEVGSM
                     LDKSGDDIYKTLHIKRKWMETYVKESFKGSNQKLERFCKTNERERKNINNKFCEQYIT
                     TFQKSDMDVQKFNEEKEKSVNSCQKEQQALKLSKCSQNQTLEAVKEMHEKSMEVLMNL
                     GTKN"
     exon            177..243
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            244..278
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            279..345
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            346..380
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            381..498
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            499..598
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            599..697
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
     exon            698..918
                     /gene="Sly"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagaagggt gcggtttgga aggtgttctc ctcttagatg agctactact gagttcttat
       61 gagaagaatg gctcttaaga aattgaaggt gataccaaag gaaggttact tattactttt
      121 ggactttgat gatgaggacg atgacataaa agtttcagag gaggctcttt cggaagtaaa
      181 gagcccagca tttgataaaa atgagaatat atcgcctcaa gcagaagcag atgaagatat
      241 gggagatgaa gtagacagta tgttggataa atctgaagta aataatccag caattggtaa
      301 agatgaaaat atatcgcctc aagtaaaagg agatgaagac atgggacatg aagtaggcag
      361 tatgttggat aaatctggag atgacattta taagacgctt cacataaaga gaaaatggat
      421 ggaaacttat gtcaaagaat ctttcaaagg cagcaaccag aaattagaaa gattttgcaa
      481 aacgaacgaa cgagagagga agaacatcaa caacaaattt tgtgagcagt atataactac
      541 atttcagaag tctgatatgg atgtacagaa attcaatgaa gaaaaagaaa aatcagtgaa
      601 tagttgtcaa aaagaacaac aagcattgaa actgtccaaa tgtagtcaga accagaccct
      661 ggaagcagtt aaagaaatgc atgagaagtc catggaggtt ttgatgaact tggggaccaa
      721 gaactaagaa atgctttttg gtgtagatgg tgaactgaaa aaaaaaatgt ctatgtttga
      781 aagagccatc atggaggata atctgaagta ctcttctact ttcccatctt cagaaaaatg
      841 aagcatgaaa aattttcact tgctggtata tatataaaac aaataaaaaa atctctaact
      901 tttttgtttc ctatgaaa
//
