LOCUS       NM_133998               2444 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus SLX9 ribosome biogenesis factor (Slx9), mRNA.
ACCESSION   NM_133998
VERSION     NM_133998.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2444)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2444)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 2444)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   4  (bases 1 to 2444)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
REFERENCE   5  (bases 1 to 2444)
  AUTHORS   Reymond,A., Friedli,M., Henrichsen,C.N., Chapot,F., Deutsch,S.,
            Ucla,C., Rossier,C., Lyle,R., Guipponi,M. and Antonarakis,S.E.
  TITLE     From PREDs and open reading frames to cDNA isolation: revisiting
            the human chromosome 21 transcription map
  JOURNAL   Genomics 78 (1-2), 46-54 (2001)
   PUBMED   11707072
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB840302.1, AF391115.1, BB007527.2, BI736563.1 and AI837476.1.
            
            On Apr 23, 2009 this sequence version replaced NM_133998.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF391115.1, BC034216.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                BB840302.1         2-29
            29-1832             AF391115.1         2-1805
            1833-2146           BB007527.2         51-364
            2147-2422           BI736563.1         314-589
            2423-2444           AI837476.1         1-22                c
FEATURES             Location/Qualifiers
     source          1..2444
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..2444
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /note="SLX9 ribosome biogenesis factor"
                     /db_xref="GeneID:108707"
                     /db_xref="MGI:MGI:1916334"
     exon            1..211
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..733
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /note="protein FAM207A; family with sequence similarity
                     207, member A"
                     /codon_start=1
                     /product="ribosome biogenesis protein SLX9 homolog"
                     /protein_id="NP_598759.1"
                     /db_xref="CCDS:CCDS23955.1"
                     /db_xref="GeneID:108707"
                     /db_xref="MGI:MGI:1916334"
                     /translation="MGKVRALRARVHRAAVRPDGDSAPGPVPRAVEPALPQSPAGGAG
                     AKDWTFVHNDIFARTQIDPSALVQRLELDQRSVVSLKRGAEPKAILPKKEKLKLRRER
                     WLQKIEAIKLAEQKLREERKRKAMVVVGDLHPLRDALPELQELEAGRQRQQARRRVTS
                     KPRPVELSRMTTVQRQQLLEEERTRFQKLLASPTYRASPLLAIGQQLAHQMQLEGGKQ
                     L"
     exon            212..320
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /inference="alignment:Splign:2.1.0"
     exon            321..389
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /inference="alignment:Splign:2.1.0"
     exon            390..540
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /inference="alignment:Splign:2.1.0"
     exon            541..609
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /inference="alignment:Splign:2.1.0"
     exon            610..2428
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      879..884
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /note="hexamer: AATAAA"
     polyA_site      910
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
     regulatory      2392..2397
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /note="hexamer: AATAAA"
     polyA_site      2422
                     /gene="Slx9"
                     /gene_synonym="1810008A18Rik; Fam207a"
                     /note="major polyA site"
ORIGIN      
        1 gtctgggagc acttccggga ggctcttcca ctagtgaggc ggcgttgcta acaggcggaa
       61 acctccaggg aagatgggga aagtgagggc gctgcgggct cgtgtgcacc gggcggccgt
      121 gagacccgac ggggattctg caccgggccc tgtgccccgc gccgtggagc cggcgctccc
      181 acaatccccg gcgggcggag cgggggcgaa ggactggaca ttcgttcaca atgacatctt
      241 tgccaggaca cagatagacc ctagtgcgtt ggtgcagagg ctggagctgg accagaggag
      301 tgtggtgtcc ctaaagagag gtgcagagcc aaaggccatt ttgcctaaga aggaaaagct
      361 gaagcttcgc cgtgagcgat ggttacagaa aattgaagcc ataaagctgg cagagcagaa
      421 gctcagggag gaacgaaagc gcaaggccat ggtggtggta ggcgacctgc accccctgag
      481 ggatgcccta cctgagctgc aggaactgga ggccggccgc cagcggcagc aagccagacg
      541 cagggtgacc agcaagcccc ggccagtgga gctcagccga atgaccacag tacagaggca
      601 gcagcttctt gaagaagaaa ggacccggtt tcagaagctg ctggccagcc caacctacag
      661 agccagtccc ctgctggcca tcgggcagca gctggcacac cagatgcagc tggaaggtgg
      721 caaacagctc tgaccaagga cagtgtgtgc catgagatct agaggactca cacgtggccg
      781 gaggtgccgg cagctcttga atcccatcct gtaccttcat ggccaactag ccagccttga
      841 gacctaggga aggcgagcta gagctgccgg tgaggacaaa taaaatgact tagggactgt
      901 ggcttccata gcctgaggac catctgtggc tttacttccc acttcaagac agccaccctg
      961 ctgaccctgg aacaagccca gggtccccag ctaggggcca gagttggggt ggttgctctt
     1021 gtggggatct gcaagggctg caccagtgtg aaactagagg cctgctaagt cgctcggtcc
     1081 ctctggcctc agcactcctt cccagctgtt tgggatcctg gtcccagcag ggccctctgc
     1141 cagccacctt gtttctcgaa ctgtttgcct tcagccaagc cgcagcttct tgtggctctg
     1201 acctctctca gcccaggtta ctcactgcct ttccctgccc tgctgtgacc agagaagcag
     1261 atggtcccgc ctggaggcag aacagcccag cccaggagcc tcttggttgg gtggcaagaa
     1321 agacctgtgt tagacactag tgagttctca gagtagcacc cacaggcccc acagctcata
     1381 tggacccatg ctccacctta tatctgggcg tgcctgtggc actactcacc ctcccacccc
     1441 cttaccctct gacagtgctc ccaagccttt tacaagggtg gtccacatac tcatggctcc
     1501 ttggccctgt gagtggagag caggcagaac aggtgagccc cctaggcctg tatggacacc
     1561 cagggcactt ggtgaatgga agtgggtaag actgaatagg cctaaactgg gtgagacaga
     1621 ggcaggcaga tctccaagta caaggtcagc ctggtctaca gatggagttc taggacagcc
     1681 agagctacac agagaaacct tgtctttaat taatttaatt aattaattaa aatagtgaat
     1741 tggcctggac acagactcaa gttcccttcg tcagaggcca tttcagcaga ctgctgagac
     1801 actgcagcta ccttgcttgg ggggcaggac aggctctcat taagagagcc taaacctacc
     1861 tgtggtgcaa gcgccgtcca gtgtgcctgg cacagcttag gaagtttcca ccttccttgt
     1921 gttgtgtgta ttaagatttc tatgatgtgg cttcaagcaa ctctggtctg gccatggcga
     1981 gcaccttttc agtatgcctc tgctggggaa cgtaggccca cccttcaggg tcctacttgg
     2041 gagagcattc cacaggccag cttcatgtac gggtcagtta cagcaggtca gggggtcaca
     2101 ccaaccgagg acactaacgt gcagtgagca ggagaggagc caagcagaca tcactgggac
     2161 tacctcagaa tctgtgcaaa atgtggtccg acgtaagtta tgtgtctaag gcttggcaga
     2221 gctgcacagc tggccagagg ctagacactg ggcaggcagg gctcgcccct tctcacctga
     2281 gacaaagcgt gtgttctcat gtggacggac acaggaagca gatcccaaga aagtggtcct
     2341 ctgctggtcg gtgggagttt gctggatttg tgtatctcct gatctttata gaataaacac
     2401 gagtcacatg gtttctgtga aacgtgcaaa aaaaaaaaaa aaaa
//
