LOCUS       NM_001081961             464 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus secreted Ly6/Plaur domain containing 2 (Slurp2), mRNA.
ACCESSION   NM_001081961
VERSION     NM_001081961.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Weinberg,R.L., Kim,S., Pang,Z., Awad,S., Hanback,T., Pan,B.,
            Bettin,L., Chang,D., Polydefkis,M.J., Qu,L. and Caterina,M.J.
  TITLE     Pain Hypersensitivity in SLURP1 and SLURP2 Knock-out Mouse Models
            of Hereditary Palmoplantar Keratoderma
  JOURNAL   J Neurosci 44 (28), e0260232024 (2024)
   PUBMED   38866482
  REMARK    GeneRIF: Pain Hypersensitivity in SLURP1 and SLURP2 Knock-out Mouse
            Models of Hereditary Palmoplantar Keratoderma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 464)
  AUTHORS   Allan,C.M., Procaccia,S., Tran,D., Tu,Y., Barnes,R.H. 2nd,
            Larsson,M., Allan,B.B., Young,L.C., Hong,C., Tontonoz,P.,
            Fong,L.G., Young,S.G. and Beigneux,A.P.
  TITLE     Palmoplantar Keratoderma in Slurp2-Deficient Mice
  JOURNAL   J Invest Dermatol 136 (2), 436-443 (2016)
   PUBMED   26967477
REFERENCE   4  (bases 1 to 464)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC115610.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC115610.1, BY339783.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 34.27 cM"
     gene            1..464
                     /gene="Slurp2"
                     /gene_synonym="2300005B03Rik; SLURP-2"
                     /note="secreted Ly6/Plaur domain containing 2"
                     /db_xref="GeneID:69462"
                     /db_xref="MGI:MGI:1916712"
     exon            1..64
                     /gene="Slurp2"
                     /gene_synonym="2300005B03Rik; SLURP-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..306
                     /gene="Slurp2"
                     /gene_synonym="2300005B03Rik; SLURP-2"
                     /note="secreted Ly-6/uPAR-related protein 2; secreted
                     Ly6/uPAR related protein-2; secreted Ly-6/uPAR
                     domain-containing protein 2"
                     /codon_start=1
                     /product="secreted Ly-6/uPAR domain-containing protein 2
                     precursor"
                     /protein_id="NP_001075430.1"
                     /db_xref="CCDS:CCDS37103.1"
                     /db_xref="GeneID:69462"
                     /db_xref="MGI:MGI:1916712"
                     /translation="MRLPFWFLLAVVLSMELAVTQGLQCHLCKGFGGCSRPSSCPWSS
                     THCVIIATRSPISFTDLPLVTKMCYSGCPDVSSLGLGPHVSIACCQSNLCNRD"
     exon            65..169
                     /gene="Slurp2"
                     /gene_synonym="2300005B03Rik; SLURP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            170..464
                     /gene="Slurp2"
                     /gene_synonym="2300005B03Rik; SLURP-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgcggaga acatgaggct tcccttctgg ttccttctgg ccgtggtctt gagcatggag
       61 ctagctgtaa cacagggcct gcaatgccac ctgtgcaagg gatttggagg atgctctcgc
      121 ccgtctagct gcccatggag ctccacccac tgtgtcatca ttgccacccg ttctcccatc
      181 agctttacag atctgcctct ggtgacgaag atgtgctaca gtggctgtcc tgatgtctcc
      241 agcttgggct taggtcctca tgtatccatc gcctgctgcc agtccaatct ctgcaacagg
      301 gactgaccac actcctccac tcccagctgg ctccacagaa caatgccatg ccccttggtt
      361 aggcctggtc cttggagatc actccagctt ggctatccca aagcccccac cccaactcac
      421 acttctttgg gaggttctga atgaagtcct gtgtaaatcc actg
//
