LOCUS       NM_001310445            5375 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus sarcolemma associated protein (Slmap), transcript
            variant 1, mRNA.
ACCESSION   NM_001310445 XM_006519724
VERSION     NM_001310445.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5375)
  AUTHORS   Rehmani,T., Dias,A.P., Applin,B.D., Salih,M. and Tuana,B.S.
  TITLE     SLMAP3 is essential for neurulation through mechanisms involving
            cytoskeletal elements, ABP, and PCP
  JOURNAL   Life Sci Alliance 7 (12), e202302545 (2024)
   PUBMED   39366759
  REMARK    GeneRIF: SLMAP3 is essential for neurulation through mechanisms
            involving cytoskeletal elements, ABP, and PCP.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5375)
  AUTHORS   Dias,A.P., Rehmani,T., Applin,B.D., Salih,M. and Tuana,B.
  TITLE     SLMAP3 is crucial for organogenesis through mechanisms involving
            primary cilia formation
  JOURNAL   Open Biol 14 (10), rsob240206 (2024)
   PUBMED   39417621
  REMARK    GeneRIF: SLMAP3 is crucial for organogenesis through mechanisms
            involving primary cilia formation.
REFERENCE   3  (bases 1 to 5375)
  AUTHORS   Dias,A.P., Rehmani,T., Salih,M. and Tuana,B.
  TITLE     Tail-anchored membrane protein SLMAP3 is essential for targeting
            centrosomal proteins to the nuclear envelope in skeletal myogenesis
  JOURNAL   Open Biol 14 (10), 240094 (2024)
   PUBMED   39378988
REFERENCE   4  (bases 1 to 5375)
  AUTHORS   Rehmani,T., Dias,A.P., Kamal,M., Salih,M. and Tuana,B.S.
  TITLE     Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3
            (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of
            Myocardium without Affecting Hippo Pathway
  JOURNAL   Int J Mol Sci 25 (5), 2888 (2024)
   PUBMED   38474134
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5375)
  AUTHORS   Mestres,I., Atabay,A., Escolano,J.C., Arndt,S., Schmidtke,K.,
            Einsiedel,M., Patsonis,M., Bolanos-Castro,L.A., Yun,M.,
            Bernhardt,N., Taubenberger,A. and Calegari,F.
  TITLE     Manipulation of the nuclear envelope-associated protein SLAP during
            mammalian brain development affects cortical lamination and
            exploratory behavior
  JOURNAL   Biol Open 13 (3) (2024)
   PUBMED   38466184
  REMARK    GeneRIF: Manipulation of the nuclear envelope-associated protein
            SLAP during mammalian brain development affects cortical lamination
            and exploratory behavior.
REFERENCE   6  (bases 1 to 5375)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 5375)
  AUTHORS   Sosinowski,T., Killeen,N. and Weiss,A.
  TITLE     The Src-like adaptor protein downregulates the T cell receptor on
            CD4+CD8+ thymocytes and regulates positive selection
  JOURNAL   Immunity 15 (3), 457-466 (2001)
   PUBMED   11567635
REFERENCE   8  (bases 1 to 5375)
  AUTHORS   Wielowieyski,P.A., Sevinc,S., Guzzo,R., Salih,M., Wigle,J.T. and
            Tuana,B.S.
  TITLE     Alternative splicing, expression, and genomic structure of the 3'
            region of the gene encoding the sarcolemmal-associated proteins
            (SLAPs) defines a novel class of coiled-coil tail-anchored membrane
            proteins
  JOURNAL   J Biol Chem 275 (49), 38474-38481 (2000)
   PUBMED   10986292
REFERENCE   9  (bases 1 to 5375)
  AUTHORS   Angrist,M., Wells,D.E., Chakravarti,A. and Pandey,A.
  TITLE     Chromosomal localization of the mouse Src-like adapter protein
            (Slap) gene and its putative human homolog SLA
  JOURNAL   Genomics 30 (3), 623-625 (1995)
   PUBMED   8825655
REFERENCE   10 (bases 1 to 5375)
  AUTHORS   Pandey,A., Duan,H. and Dixit,V.M.
  TITLE     Characterization of a novel Src-like adapter protein that
            associates with the Eck receptor tyrosine kinase
  JOURNAL   J Biol Chem 270 (33), 19201-19204 (1995)
   PUBMED   7543898
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK164911.1, AK141597.1, DV651439.1, DV655219.1, DV646594.1 and
            BP762661.1.
            
            On Jul 14, 2015 this sequence version replaced XM_006519724.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141597.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2146              AK164911.1         272-2417
            2147-3778           AK141597.1         2420-4051
            3779-4075           DV651439.1         430-726
            4076-4673           DV655219.1         3-600
            4674-5345           DV646594.1         20-691
            5346-5375           BP762661.1         44-73               c
FEATURES             Location/Qualifiers
     source          1..5375
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 16.09 cM"
     gene            1..5375
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /note="sarcolemma associated protein"
                     /db_xref="GeneID:83997"
                     /db_xref="MGI:MGI:1933549"
     exon            1..1297
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     CDS             1100..3637
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /note="isoform 1 is encoded by transcript variant 1;
                     sarcolemmal membrane-associated protein;
                     sarcolemmal-associated protein"
                     /codon_start=1
                     /product="sarcolemmal membrane-associated protein isoform
                     1"
                     /protein_id="NP_001297374.1"
                     /db_xref="CCDS:CCDS79284.1"
                     /db_xref="GeneID:83997"
                     /db_xref="MGI:MGI:1933549"
                     /translation="MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNA
                     TFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDI
                     IQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSM
                     YSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLE
                     VMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVE
                     RSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQK
                     GQAEKKELQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKEC
                     SSLGIQVDDFLPKINGSTEKEHLLSKSGGDCTFIHQFLECQKKLMVQGHLTKVVEESK
                     LSKENQAKAKESDLSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGTQS
                     ETEAKQDIQHLRKELVEAQELARTSKQKCFELQALLEEERKAYRNQVEESAKQIQVLQ
                     VQLQKLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLRQAAAEAVSERDTDFVSLQE
                     ELKKVRAELEGWRKAASEYENEIRSLQSSFQLRCQQCEDQQREEATRLQGELEKLKKE
                     WDVLETECHSLKKENVLLSSELQRQEKELHNSQKQSFELTSDLSILQMTRKELEKQVG
                     SLKEQHLRDAADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDE
                     LKQCKDNLKLLREKGNNKPWPWMPMLAALVAVTAMVLYVPGLARASP"
     exon            1298..1445
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1518
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1555
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1618
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1714
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1786
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1927
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2065
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2234
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2235..2285
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2286..2336
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2337..2399
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2400..2459
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2460..2540
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2541..2600
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2601..2723
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2798
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            2799..3119
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            3120..3237
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            3238..3409
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            3410..3544
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     exon            3545..5365
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5338..5343
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /note="hexamer: AATAAA"
     polyA_site      5358
                     /gene="Slmap"
                     /gene_synonym="D330001L02Rik; Miranda; mKIAA1601; Slap"
                     /note="major polyA site"
ORIGIN      
        1 gtcggaaagt ttcctgcctc gtccgccacc gcctgagctt gccgcactgg ctgcgagtgg
       61 aggaggctgc ggcggaccca gccccggcct ccaggcctct ccctccacct ccgggccagc
      121 ctccctcccc caccccgtcg tcctgcggga gccgccagtc cctgcgatgc gaccctcgcg
      181 aggacgctcc tgaggggagg tggcccatgt gctgagcagc agagcccgag agctccgaga
      241 aaccaacttc ccgccggccc gcccgtcggc ccgctcgccc gcccggtcgc ccgagcctcc
      301 ccggggtagc tcctcgctct gtccgcaccg gcctgcagag ccgggtcccc gccctggtcg
      361 cggggacacc cgtcaggtgc ccgggactcg cgacccagac gccgcccgtg ccccggcagc
      421 cctcccacgc ctccagcccg ggatcgcagc ctcggctcac gctgggccgg ggacccctgc
      481 cactcccggg cggcctcggc gcagcagggc aatgcagccc ggcccgctgg ccctctagtc
      541 ctcctcgtcc gtccccgcac ctcttctcag ccccgaggcc ccgcggtggc tgcccggagg
      601 tcctccgcgc ctcttccttg agccccgaag gaccttcctg gctgcgcgag tcaaccctct
      661 tcatgctgca gtgctgcacc gtttccgcta ccgaagggga caagcggccg ggatctcaaa
      721 caaaacacaa gaactggtgt gtgactcatc tgctcggata cctcctgtcc ccaaactgtc
      781 ttccaggagt tttcttggcc gaagctgccc aatgtttgag ccttttcttc ctagggaaga
      841 tggactgaaa gctgctagtt ggggactttt tttggtcaag gtgcctctgt attttaaagg
      901 aggtgatggg gcttgcgctg gcttgtcctc ctgcccaatt gaagagttgt tgatgttcac
      961 tggttatgct tagacaatgc gcagtttgtt ttaatttaaa aattttgggg ggttaggggg
     1021 tgtaggcttg agaagagcat tccgaacctg gaggagctcc tcattgtccc tggtccagac
     1081 accccccagc ctgtcctcga tgccgtcagc cttggccatc ttcacttgcc gcccgaactc
     1141 gcacccgttt caggagcgtc atgtctacct ggacgagccc atcaagatcg gccgctcggt
     1201 ggcacgctgt cgaccagcgc agaataatgc cacctttgat tgcaaagtgc tgtcaaggaa
     1261 ccatgccctc gtctggtttg atcacaagac gagcaagttc tatctccaag acactaaaag
     1321 tagtaatggt acctttataa atagccagag attgagtcga ggctctgaag aaagtccgcc
     1381 atgcgaaatt ctttctggtg acatcatcca gtttggggtg gatgtgacgg agaatacccg
     1441 gaaagttacc catgggtgta ttgtttccac aataaaactt tttctaccag atggtatgga
     1501 agcccgactt cgttcagatg tcatccatgc tccattaccg agtcctgtag acaaagttgc
     1561 tgctaacact ccaagtatgt actctcagga actattccaa ctttctcagt atctacagga
     1621 ggccttacat cgggaacaga tgttggaaca gaagttagcc acacttcagc ggctactagc
     1681 catcacccaa gaggcttcag atactagttg gcaggcttta atagatgaag atagactctt
     1741 atcacggtta gaagttatgg gaaaccagtt gcaggcatgc tccaaaaatc aaacagaaga
     1801 cagtttacgg aaggagctga ttgcactgca ggaggataaa cacagctatg aaaccacagc
     1861 caaagagtcc ctgaggcggg ttcttcagga gaaaatcgaa gtggttagaa aactttcaga
     1921 agttgagcga agtctgagta atactgaaga tgaatgtacc cacctgaaag agatgaatga
     1981 gcgcactcag gaagagttga gagaattagc caataaatat aatggagcag ttaatgaaat
     2041 taaagattta tctgataaat taaaggtagc agagggaaaa caagaggaaa tccaacagaa
     2101 gggacaagct gagaagaagg aattacagac gaaaattgat gaaatggaag aaaaagaaca
     2161 agagctccag gcaaaaatcg aagctttgca agctgataac gacttcacca atgaaaggct
     2221 gacagctctg caagtacggt tagaacacct gcaggagaaa acccttaaag aatgcagcag
     2281 cttagggata caagttgatg acttcttacc taaaataaat gggagcacag aaaaagagca
     2341 cttgctttca aagagtggcg gggactgcac ttttattcat caattcctag agtgccagaa
     2401 gaagctgatg gtccaagggc atctaaccaa agtggtagaa gaatcaaagc tttcaaaaga
     2461 aaatcaggca aaagcaaagg aatccgactt atcagacact ctgagtccaa gcaaggaaaa
     2521 aagcagcgac gacactacag acgcccagat ggatgagcaa gacctaaatg aaccccttgc
     2581 taaggtgtct ctattaaaag atgacttaca gggtacccag tcagaaactg aggccaaaca
     2641 agacattcag catcttcgca aagaattggt ggaagcccag gagctagcta gaacaagtaa
     2701 acaaaaatgc tttgaacttc aagctctttt ggaagaagaa cgaaaagcct atcgaaatca
     2761 agttgaagaa tcagctaaac aaatacaggt tcttcaagtc cagctgcaga agttacacat
     2821 ggacatggag aatctccagg aggaaaagga cacggaaatc tccagcacaa gagataaatt
     2881 gcttagtgcc caagatgaga ttttgctcct tcgtcaagca gcagcagagg ctgtgtctga
     2941 gcgggacact gactttgttt ctttgcaaga agagcttaag aaggtcagag cggagcttga
     3001 gggctggagg aaagcagcgt ctgaatacga gaatgaaatc agaagtctgc agagcagctt
     3061 ccagcttaga tgtcagcagt gtgaagacca gcaaagggag gaggcaacaa ggttgcaagg
     3121 tgagctggag aagttgaaga aggagtggga tgtactggaa acggaatgcc attctctaaa
     3181 aaaggagaac gtgttgttgt cttcagaact gcagcgacaa gagaaagaat tgcacaattc
     3241 tcagaagcag agttttgaac tcacgagtga cctcagcatc cttcagatga ctaggaaaga
     3301 gctggagaag caagtgggat ccttgaaaga acaacacctt cgggatgcag ctgacctaaa
     3361 aactctcctc agtaaggctg aaaaccaagc aaaggatgta cagaaagagt atgaaaagac
     3421 acagactgtt ctctcagaac tgaagttgaa gtttgaaatg actgagcagg aaaagcaatc
     3481 aatcacagat gagctcaaac agtgtaaaga caacctgaag ctgctgcgag agaaaggaaa
     3541 taataaaccc tggccctgga tgcccatgtt ggcggccctg gttgcggtga cagctatggt
     3601 gctgtatgta ccaggtctgg ccagagcttc tccatgacag tgtgtcttga gtctgtacac
     3661 cgtcctccct ctagaagccg gcagcacact catgctgggg acaagcagaa ccattctctt
     3721 cctttttacc tcttaaaaca gcaaagtgca agaatacagc tggagggtca ttgctttaat
     3781 ttatataaaa tatatctgtc tatagagagg atagaaagtt gtgaatttat tcggttttac
     3841 atgtaatttt taaattagta tgttgagatt ctgaatatta tggtggccta aagtacgctt
     3901 cttagtgcac caaattattt ataccataaa tttatagata ttttactctg aattctaatg
     3961 gccacacaat tcatttttct gattcgataa ctactcaaac cgaacaacca atacatacat
     4021 gggaatagag gccctgtgtg ctcagtgcct atcagtttga atatatacac acacacatat
     4081 atatattttt tttacatatt tacgccattt ttacttgtta taaaaccact gagctattgg
     4141 gaacaagact tagacaatta tttgtgtgga tttttttttt aaaggaaaac tacatttgaa
     4201 aaatattctc ttataataat tatttgggga atacatacgt gtttgttcag ccttaatgtg
     4261 acttgaagat gtgaaggaca tcagctttga aaactttcca tgagagtttg tattttcttg
     4321 agcaaactga aatattactg ggagcaaaaa cataagtgca taatttcaat gcaatcaacc
     4381 aaactgttga gtgaattgga atgtaactta ctaaacctca tgtatttaag aaatgttttc
     4441 tttaaaagcc aagttacctt ctcatataca gcagtttaga aagcatgatt tttttttctg
     4501 tcatctgttc ctccaagcat gtttaattga aagaagaatt atatctgttt agataagctt
     4561 ttattgactt aatttggtta tgatgtggag ctaattcaca ttcaaggtga actgatgttc
     4621 tctgctagca gatttcttgg ttgggtatac aaatggttat tctctttttg ttgttaattg
     4681 gaacagcctg tcaattagta gcactattcc caagattggc attgttccac acacagtgac
     4741 acacctcagc actgcttggc attatacatt taaacacaga ggttaaagtt tagctgtggt
     4801 tttgtgcagc accatagtga tgtcaatgtc ctaaagtatc acgtgcttag gttttcttca
     4861 gtcagggaag actggaaggg aaggccagtg agttggtttg aatgttgtat gagaacaccc
     4921 agatctagcc agatattgaa aaaggacttt aggatataat ttgtctgtga tgtttggcag
     4981 tcattatttt tactttaaaa gttgtattta aagctatttg ggattgttgc cgggagaatc
     5041 actatattca tggaggaatt agccacaaat gacttgtaga aaatactgtc gtatagttca
     5101 ttttaccatt ctctgttgca ggaagccacc ccaccacaga atgctgatat gccagtggta
     5161 cccagtacct cttgtatata gttattgcaa atactgttat gaaatgcata acttcaaaat
     5221 tacctttttt aaagtaaata attgtttgaa atctattttg taaagataaa acgtacaata
     5281 gaatttctgg agtacagatt aaactatttg cactaacaca cgtgatgtgc atgatttaat
     5341 aaaataactt taatctccct ttgcaaaaaa aaaaa
//
