LOCUS       NM_175499               4243 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus SLIT and NTRK-like family, member 6 (Slitrk6), mRNA.
ACCESSION   NM_175499
VERSION     NM_175499.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4243)
  AUTHORS   Matsumoto,Y., Miwa,H., Katayama,K.I., Watanabe,A., Yamada,K.,
            Ito,T., Nakagawa,S. and Aruga,J.
  TITLE     Slitrk4 is required for the development of inhibitory neurons in
            the fear memory circuit of the lateral amygdala
  JOURNAL   Front Mol Neurosci 17, 1386924 (2024)
   PUBMED   38736483
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4243)
  AUTHORS   Jones,M.R., Dilai,S., Lingampally,A., Chao,C.M., Danopoulos,S.,
            Carraro,G., Mukhametshina,R., Wilhelm,J., Baumgart-Vogt,E., Al
            Alam,D., Chen,C., Minoo,P., Zhang,J.S. and Bellusci,S.
  TITLE     A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b
            Signaling on Epithelial Tip Progenitor Cells During Early Mouse
            Lung Branching Morphogenesis
  JOURNAL   Front Genet 9, 746 (2019)
   PUBMED   30728831
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4243)
  AUTHORS   Quintana-Urzainqui,I., Kozic,Z., Mitra,S., Tian,T., Manuel,M.,
            Mason,J.O. and Price,D.J.
  TITLE     Tissue-Specific Actions of Pax6 on Proliferation and
            Differentiation Balance in Developing Forebrain Are Foxg1 Dependent
  JOURNAL   iScience 10, 171-191 (2018)
   PUBMED   30529950
REFERENCE   4  (bases 1 to 4243)
  AUTHORS   Memic,F., Knoflach,V., Morarach,K., Sadler,R., Laranjeira,C.,
            Hjerling-Leffler,J., Sundstrom,E., Pachnis,V. and Marklund,U.
  TITLE     Transcription and Signaling Regulators in Developing Neuronal
            Subtypes of Mouse and Human Enteric Nervous System
  JOURNAL   Gastroenterology 154 (3), 624-636 (2018)
   PUBMED   29031500
REFERENCE   5  (bases 1 to 4243)
  AUTHORS   Park,K.U., Randazzo,G., Jones,K.L. and Brzezinski,J.A. 4th.
  TITLE     Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar
            Interneurons in the Mouse Retina
  JOURNAL   Invest Ophthalmol Vis Sci 58 (2), 1137-1150 (2017)
   PUBMED   28199486
REFERENCE   6  (bases 1 to 4243)
  AUTHORS   Bird,A.D., Tan,K.H., Olsson,P.F., Zieba,M., Flecknoe,S.J.,
            Liddicoat,D.R., Mollard,R., Hooper,S.B. and Cole,T.J.
  TITLE     Identification of glucocorticoid-regulated genes that control cell
            proliferation during murine respiratory development
  JOURNAL   J Physiol 585 (Pt 1), 187-201 (2007)
   PUBMED   17901120
REFERENCE   7  (bases 1 to 4243)
  AUTHORS   Yoshida,Y., Han,B., Mendelsohn,M. and Jessell,T.M.
  TITLE     PlexinA1 signaling directs the segregation of proprioceptive
            sensory axons in the developing spinal cord
  JOURNAL   Neuron 52 (5), 775-788 (2006)
   PUBMED   17145500
REFERENCE   8  (bases 1 to 4243)
  AUTHORS   Aruga,J.
  TITLE     Slitrk6 expression profile in the mouse embryo and its relationship
            to that of Nlrr3
  JOURNAL   Gene Expr Patterns 3 (6), 727-733 (2003)
   PUBMED   14643680
  REMARK    GeneRIF: Slitrk6 gene expression profile in the mouse embryo.
REFERENCE   9  (bases 1 to 4243)
  AUTHORS   Aruga,J., Yokota,N. and Mikoshiba,K.
  TITLE     Human SLITRK family genes: genomic organization and expression
            profiling in normal brain and brain tumor tissue
  JOURNAL   Gene 315, 87-94 (2003)
   PUBMED   14557068
REFERENCE   10 (bases 1 to 4243)
  AUTHORS   Aruga,J. and Mikoshiba,K.
  TITLE     Identification and characterization of Slitrk, a novel neuronal
            transmembrane protein family controlling neurite outgrowth
  JOURNAL   Mol Cell Neurosci 24 (1), 117-129 (2003)
   PUBMED   14550773
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK044796.1, BC138664.1, AK029275.1 and BB374017.1.
            
            On Dec 12, 2009 this sequence version replaced NM_175499.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029275.1, SRR1660821.78464.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1790              AK044796.1         2-1791
            1791-3658           BC138664.1         1308-3175
            3659-4235           AK029275.1         3583-4159
            4236-4243           BB374017.1         193-200
FEATURES             Location/Qualifiers
     source          1..4243
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 57.2 cM"
     gene            1..4243
                     /gene="Slitrk6"
                     /gene_synonym="4832410J21Rik; Sltk6"
                     /note="SLIT and NTRK-like family, member 6"
                     /db_xref="GeneID:239250"
                     /db_xref="MGI:MGI:2443198"
     exon            1..522
                     /gene="Slitrk6"
                     /gene_synonym="4832410J21Rik; Sltk6"
                     /inference="alignment:Splign:2.1.0"
     exon            523..4242
                     /gene="Slitrk6"
                     /gene_synonym="4832410J21Rik; Sltk6"
                     /inference="alignment:Splign:2.1.0"
     CDS             547..3069
                     /gene="Slitrk6"
                     /gene_synonym="4832410J21Rik; Sltk6"
                     /note="slit and trk like gene 6; neuronal transmembrane
                     protein Slitrk6; SLIT and NTRK-like protein 6"
                     /codon_start=1
                     /product="SLIT and NTRK-like protein 6 precursor"
                     /protein_id="NP_780708.1"
                     /db_xref="CCDS:CCDS27326.1"
                     /db_xref="GeneID:239250"
                     /db_xref="MGI:MGI:2443198"
                     /translation="MKLWTYLLYPSLLACLSLQSQSPMPSVRGSCDTLCNCEEKDGIM
                     IINCEEKGINKLSQISVPPSRPFHLSLLNNGLTMLHTNDFSGLTNALSIHLGFNNIAD
                     IETGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITIIEPSAFSKLN
                     RLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDN
                     KWACNCELLQLKNWLENMPPQSIIGDVICYSPPPFKGSVLSRLKKESFCPTPPVYEEH
                     EDPSGSLLAITSSTSDSRLSSKNTSILKQPTKAPGLIPYLTKPSTQLPVPYCPIPCNC
                     KVLSPSGLLIHCQERNIESLSDLQPPPHNPRKLILAGNIIHTLMKSDLTDYFTLEMLH
                     LGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLNKGMFLGLHSLEYLYLEYNAVKEIL
                     PGTFNPMPKLKVLYLNNNLLQVLPAHIFLGIPLTRVNLKTNQFTHLPVSNILDDLDFL
                     IQIDLEDNPWDCSCDLVGLQQWIHKLGKGTMTDDILCTSPGHLDKKELKALNSDLLCP
                     GLVNNPSMPTQTTYVIVTSPTVAADTASTLFSSLTDAVPLSVLILGLLIVFITIVFCA
                     AGIVVFVLHRRRRYKKKKVEEQLRDNSPVHLQYSMYGHKTTHHTTERPSSSLYEQHMV
                     SPMVHVYRSPSFGPKHLEEVEERNDKEGNDAKHLQRSLLERENHSPLTGSNMKYKTTD
                     QSTDFISFQDASLLYRNILEKERELQQLGITEYLRKNLAQLQPEVEVNYPGAHEELKL
                     METLMYSRPRKVLVEQTKNEYFELKANLHAEPDYLEVLEQQT"
     regulatory      4221..4226
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slitrk6"
                     /gene_synonym="4832410J21Rik; Sltk6"
                     /note="hexamer: AATAAA"
     polyA_site      4241
                     /gene="Slitrk6"
                     /gene_synonym="4832410J21Rik; Sltk6"
                     /note="major polyA site"
ORIGIN      
        1 gtctctttat ttacgcctac ctcccagtcc ttggcaatct gactaataac aaactgagct
       61 aactagaaag actcgaccga gaggaaggag agctgtacag cagtctggat ctacaaccaa
      121 agaaagcaag agtgaacacc cccgggtctc cgcaaagcgt cttgtttatt tacagtgatc
      181 agcagcttgt caatggttaa ctatatgcaa aacaaagtca gcatagctgt gaagtatgct
      241 gtgaatatta attgggggag aaagggactc tggcttcagg atgctccagt gtgtgttctg
      301 cctgcaagac tttcaatgaa aattaagggc tcagtgtttc gccttcgacc agatgtttta
      361 actttctgaa gctatgagac ttgagaaaaa gtgatatttg aggagaaagt gcactgtggt
      421 cctgtggttg gtgttttctt tttcaataaa gaacctgatt gactttggac acttcttcca
      481 gctgggcatt tcatatcgca ccaggaagtg actgctttac agagtcagat ccaatcatat
      541 gacaaaatga agctgtggac ttatctcctt tatccatctc ttcttgcttg tctgtctcta
      601 cagtcccagt caccaatgcc ctcagtcaga ggctcttgcg acactctttg taattgtgag
      661 gagaaagatg gcataatgat aataaactgt gaagaaaaag gaatcaataa attatcccaa
      721 atcagtgtgc caccatcacg acctttccac ttaagtttat taaataatgg cttgacaatg
      781 cttcacacga acgacttttc tggacttacc aatgcccttt caatacacct tggatttaac
      841 aatatagcag acatagagac tggtgcattt aatggccttg ggcttcttaa gcaacttcat
      901 atcaatcata attctttgga aattcttaaa gaggatacct tccatggttt ggagaacctg
      961 gaattcttgc aggctgataa taatttcatt acgataattg aaccaagtgc cttcagcaag
     1021 ctcaacaggc taaaggtgtt gattttaaat gacaacgcta ttgagagtct tcctccaaac
     1081 atatttcgat ttgttccttt aacccatcta gatcttcgtg ggaaccagtt gcaaacattg
     1141 ccttatgttg gctttttaga acacattggc cggatattgg atctccaatt ggaggacaat
     1201 aagtgggcct gcaattgtga attgttgcag ctaaaaaact ggctagaaaa tatgcctcca
     1261 caatctataa ttggtgatgt gatatgctac agccctccac ctttcaaagg gagtgtactg
     1321 agtcgcctga aaaaggaatc tttttgccct actccaccag tatacgaaga gcatgaggat
     1381 ccatcaggat ctttgctggc cataacatct tcaacaagtg acagccgcct atcaagcaag
     1441 aatacatcca ttttgaaaca acctaccaaa gcaccaggtt tgataccata ccttacaaag
     1501 ccatccactc agcttccagt accttattgt cctatccctt gcaattgcaa agttctctcc
     1561 ccttcggggc ttcttatcca ctgtcaggag cgcaatatag aaagcttgtc agatctacag
     1621 cctcctccac acaaccctag aaagctgatt cttgcaggca acatcattca caccttaatg
     1681 aagtctgacc tcacagacta tttcactttg gaaatgcttc acttgggaaa caaccgcatt
     1741 gaagttctgg aagaaggatc gtttatgaat ctgacacgac tccagaagct ttatctcaat
     1801 ggcaatcatc tgaccaaact caataaaggc atgttccttg gtctccacag tctcgagtat
     1861 ttgtatcttg agtacaatgc ggtaaaggaa atattaccag ggaccttcaa cccaatgcct
     1921 aaactgaaag ttctttattt aaataacaat ctccttcaag ttttaccggc acatatcttt
     1981 ttaggtattc ctctaactag agtaaatctt aaaacaaacc aattcaccca tttacctgta
     2041 agcaacatct tagatgacct tgacttcctg atacagattg accttgagga taacccctgg
     2101 gactgctctt gtgacttggt tggattgcag caatggatcc acaagcttgg caagggcacc
     2161 atgactgatg atatcctctg cacttcccca gggcatcttg acaagaaaga attaaaagcc
     2221 ctcaacagtg atcttctttg ccctggttta gtgaataatc cttccatgcc aacccagact
     2281 acttatgtta ttgtcacttc tcccacagtg gcggcagata cagctagtac actcttcagt
     2341 tctctcactg atgctgtgcc cctgtcagtt ctaatattag gactcctgat tgtgttcata
     2401 actattgtat tctgtgccgc ggggatcgtg gtttttgtcc tccaccgtag gagaagatat
     2461 aagaagaaaa aagtagagga acaactgaga gacaacagtc ctgtacactt gcagtacagc
     2521 atgtatggtc ataaaacaac ccaccataca acggaaagac cctcttcctc tctctatgaa
     2581 caacacatgg tgagcccaat ggttcatgtc tacagaagtc catcctttgg tccaaagcat
     2641 ttggaagaag ttgaggaaag aaatgataaa gaaggaaatg atgcaaaaca tcttcaaagg
     2701 agcctgttag aacgagaaaa tcattcacca ctcacaggtt caaatatgaa atacaaaact
     2761 acagaccaat caacagattt catatccttt caggatgcaa gcttattata taggaacatt
     2821 ttggagaaag agagggaact tcagcaactt ggcatcacag agtacctaag aaaaaatctt
     2881 gctcagctcc agccagaggt ggaggttaac tatcctggag cccacgagga gctaaaatta
     2941 atggaaacgt tgatgtactc acgaccaagg aaggtgttgg tagaacagac taaaaatgaa
     3001 tactttgagc tcaaagctaa cttgcatgct gaacccgact acttagaagt cttggagcag
     3061 caaacataga ggggctgctt gtgggctttt gcagaaatgc tgggattctg acttaagttc
     3121 acacttttga aataagtgcc ttacgtgggt gttatcaatc agaattcagc acagccgtaa
     3181 tcctatgaga gatgaaagaa gaaagtgaaa ctcagggaca attgaggaag ccatggcatt
     3241 atcatcaggc aatatagcct gttccaaata aaacaagtcc ttgcatataa ctgttgcaag
     3301 gagtacgtag tattgctcca tatgcttaca agtatttcat agaatttctc ttgcacacct
     3361 aaagggttga acacataaaa agctccagtt ttcttggata ctctattcat gactaaatac
     3421 aattaaattt catcagttaa gcatatacct gtatatatat acatagtatg taaggaattt
     3481 attcataatc acatatatgt cagaaattta tactgtcaat cacactaaat tttctcacaa
     3541 aaagtgaaag gggaactgga acttaaattt aaaaagtggc aatagtaagt gaaaatgtac
     3601 aatttgtaat tacgtgcacc attaacgatt ccgaattttc aacaaagggt gccattgcta
     3661 aggtttctga attcagactc acgatggcaa atagttcctg tgggataaat aagcaaatgt
     3721 gtgagtttaa tctacacatt ttctgtggat atcttttgat gtaatgctgc tgtgaaccta
     3781 aggtatgtga tttgtgttcg acattctatt cttcttggga tatttttttt taaatgctac
     3841 tgagattcta ctgtatatat gattagagca cttagtaagt ttgcttcttt tcatagtgtt
     3901 aattatttgt acaactggat gataatgata agaaaacatg tcttttgtgg catgtaaatc
     3961 aaaggtataa aatgaatagt aaaacttatt ttatttttat tgacatacac tgataggtcg
     4021 tgtagattag tagcaagagg cgtttctaca ggtaagtgtt ctgagcttcc tcaggagagg
     4081 gacagtgtag ctttatttta caagaaggta tcactagatt tctatgaact atttattctg
     4141 tacagttttg tatatttttg gttcacaaga taattatact tgggtgcctt ttaagaaagt
     4201 ttaagattat tgctcacttc aataaaagta aaatgaaaac ata
//
