LOCUS       NM_198865               4829 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus SLIT and NTRK-like family, member 5 (Slitrk5),
            transcript variant 1, mRNA.
ACCESSION   NM_198865
VERSION     NM_198865.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4829)
  AUTHORS   Matsumoto,Y., Miwa,H., Katayama,K.I., Watanabe,A., Yamada,K.,
            Ito,T., Nakagawa,S. and Aruga,J.
  TITLE     Slitrk4 is required for the development of inhibitory neurons in
            the fear memory circuit of the lateral amygdala
  JOURNAL   Front Mol Neurosci 17, 1386924 (2024)
   PUBMED   38736483
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4829)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 4829)
  AUTHORS   Goodyer,W.R., Beyersdorf,B.M., Duan,L., van den Berg,N.S.,
            Mantri,S., Galdos,F.X., Puluca,N., Buikema,J.W., Lee,S., Salmi,D.,
            Robinson,E.R., Rogalla,S., Cogan,D.P., Khosla,C., Rosenthal,E.L.
            and Wu,S.M.
  TITLE     In vivo visualization and molecular targeting of the cardiac
            conduction system
  JOURNAL   J Clin Invest 132 (20), e156955 (2022)
   PUBMED   35951416
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4829)
  AUTHORS   Markenscoff-Papadimitriou,E., Binyameen,F., Whalen,S., Price,J.,
            Lim,K., Ypsilanti,A.R., Catta-Preta,R., Pai,E.L., Mu,X., Xu,D.,
            Pollard,K.S., Nord,A.S., State,M.W. and Rubenstein,J.L.
  TITLE     Autism risk gene POGZ promotes chromatin accessibility and
            expression of clustered synaptic genes
  JOURNAL   Cell Rep 37 (10), 110089 (2021)
   PUBMED   34879283
REFERENCE   5  (bases 1 to 4829)
  AUTHORS   Sun,J., Shin,D.Y., Eiseman,M., Yallowitz,A.R., Li,N., Lalani,S.,
            Li,Z., Cung,M., Bok,S., Debnath,S., Marquez,S.J., White,T.E.,
            Khan,A.G., Lorenz,I.C., Shim,J.H., Lee,F.S., Xu,R. and
            Greenblatt,M.B.
  TITLE     SLITRK5 is a negative regulator of hedgehog signaling in
            osteoblasts
  JOURNAL   Nat Commun 12 (1), 4611 (2021)
   PUBMED   34326333
  REMARK    GeneRIF: SLITRK5 is a negative regulator of hedgehog signaling in
            osteoblasts.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4829)
  AUTHORS   Beaubien,F. and Cloutier,J.F.
  TITLE     Differential expression of Slitrk family members in the mouse
            nervous system
  JOURNAL   Dev Dyn 238 (12), 3285-3296 (2009)
   PUBMED   19924824
REFERENCE   7  (bases 1 to 4829)
  AUTHORS   Yoshida,Y., Han,B., Mendelsohn,M. and Jessell,T.M.
  TITLE     PlexinA1 signaling directs the segregation of proprioceptive
            sensory axons in the developing spinal cord
  JOURNAL   Neuron 52 (5), 775-788 (2006)
   PUBMED   17145500
REFERENCE   8  (bases 1 to 4829)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   9  (bases 1 to 4829)
  AUTHORS   Aruga,J., Yokota,N. and Mikoshiba,K.
  TITLE     Human SLITRK family genes: genomic organization and expression
            profiling in normal brain and brain tumor tissue
  JOURNAL   Gene 315, 87-94 (2003)
   PUBMED   14557068
REFERENCE   10 (bases 1 to 4829)
  AUTHORS   Aruga,J. and Mikoshiba,K.
  TITLE     Identification and characterization of Slitrk, a novel neuronal
            transmembrane protein family controlling neurite outgrowth
  JOURNAL   Mol Cell Neurosci 24 (1), 117-129 (2003)
   PUBMED   14550773
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY728649.1, BY274593.1, CB526109.1, BC065107.1, BQ769394.1 and
            AK173062.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.118585.1,
                                           SRR1660811.245693.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-257               BY728649.1         19-275
            258-317             BY274593.1         73-132
            318-484             CB526109.1         374-540
            485-1075            BC065107.1         104-694
            1076-1100           BQ769394.1         469-493
            1101-2730           BC065107.1         720-2349
            2731-3014           AK173062.1         1762-2045
            3015-3965           BC065107.1         2350-3300
            3966-4390           BC065107.1         3310-3734
            4391-4829           BC065107.1         3736-4174
FEATURES             Location/Qualifiers
     source          1..4829
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 57.86 cM"
     gene            1..4829
                     /gene="Slitrk5"
                     /gene_synonym="2610019D03Rik"
                     /note="SLIT and NTRK-like family, member 5"
                     /db_xref="GeneID:75409"
                     /db_xref="MGI:MGI:2679448"
     exon            1..609
                     /gene="Slitrk5"
                     /gene_synonym="2610019D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            610..4807
                     /gene="Slitrk5"
                     /gene_synonym="2610019D03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             618..3491
                     /gene="Slitrk5"
                     /gene_synonym="2610019D03Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; slit and trk like gene 5; SLIT and NTRK-like
                     protein 5"
                     /codon_start=1
                     /product="SLIT and NTRK-like protein 5 isoform 1
                     precursor"
                     /protein_id="NP_942565.1"
                     /db_xref="CCDS:CCDS27328.1"
                     /db_xref="GeneID:75409"
                     /db_xref="MGI:MGI:2679448"
                     /translation="MHVCCPPVTLEQDLHRKMHSWMLQTLAFAVTSLVLSCAETIDYY
                     GEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLSRLYPNEFV
                     NYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQV
                     DYNYISVIEPNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYV
                     GLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLD
                     EVSKQELCPRKLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGT
                     RQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECPTACTCNLQISDLGLNVN
                     CQERKIESIAELQPKPYNPKKMYLTENYITVVRRTDFLEATGLDLLHLGNNRISMIQD
                     RAFGDLGNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQAGTFDPVPNLQ
                     LLFLNNNQLQAMPSGVFSGLTLLRLNLRGNSFTSLPVSGVLDQLTSLIQIDLHDNPWD
                     CTCDVVGMKLWIEQLKVGVLVDEVICKAPKKFAETYMRSIKSELLCPDYSDVVVSTPT
                     PSSIQVPSRTNAATPAVRLNSTGTPAGLGAGTGASSVPLSVLILSLLLVFIMSVFVAA
                     GLFVLVMKRRKKNQSDHTSTNNSDVSSFNMQYSVYGGGGGGGGGHPHAHVHHRGPALP
                     KVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQPP
                     PPPQQPQQQPPPQMQMQPGEEERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRG
                     ILEPDKHCSTTPAGSSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGESRLREPV
                     LYSPPGAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF"
ORIGIN      
        1 atagagcgtc caagctgcca ggacatgcca caggcataga gcaacgctgc tcctaccccc
       61 cttggacccc tcaaaggatg tcggagataa agagttgcaa ataatgagga tcgtgcgccg
      121 catctgggga gggatagcaa aaatccgctg caaaccccgg gagcggtgaa gccgccaaga
      181 ggatgcggga gcctttcaaa tactaattag gggccgcgat tgcaggtttg ccttggggac
      241 agaggcatcc agggtccggt ggtcctggcg tttgggggag aagagcgcag cggaggaacc
      301 gccgccgaag cagcccgggg gccagtacca ccttctctcg ccccctcact accatgtaca
      361 gtgtgcgctg caagaagaag gcgggcgatg aacgcacacc ctcgagcccc actccttctg
      421 gttcgtcctg gggcgtgcga cactgactag gggggaatgt ggtgaagacg ccgacccgga
      481 gaggctaggg gggaggggag ggcggcccgc gcgatcccag gccggagggt gccaagagcc
      541 cgaggcggct ggagggggcg gctgccatcg ctgggtcgga gaaagttgcc cccagtgcag
      601 atgggaacag aggtaaaatg cacgtttgct gccccccagt aactttggaa caggaccttc
      661 acagaaaaat gcatagctgg atgctgcaga ctctagcatt tgctgtaaca tctctcgtcc
      721 tttcctgtgc agaaaccatc gattattatg gggaaatctg tgacaatgca tgtccttgtg
      781 aggaaaagga cggcatttta actgtgagct gtgaaaaccg gggcatcatc agtctctctg
      841 aaattagccc tccccgtttc ccaatctatc acctcttgtt gtctggaaac cttctgagcc
      901 gcctctatcc caatgagttt gttaattaca caggggcttc aattttacat ctgggtagca
      961 atgttatcca agacattgag actggggctt ttcatgggct gaggggtttg aggcgactcc
     1021 atctaaacaa taataaattg gaacttctgc gagatgatac ctttcttggc ttggagaact
     1081 tagaatacct gcaggtcgat tacaattaca tcagtgtcat tgaacccaat gcttttggga
     1141 aactgcacat gctgcaggtg cttatcctca atgacaatct cttgtcaggt ttacccaaca
     1201 atcttttccg ttttgtgccc ttaacgcact tggacttgag ggggaacagg ctgaaacttc
     1261 tgccctatgt ggggctgttg caacacatgg ataaagttgt ggaattacag ctggaggaaa
     1321 acccctggaa ttgctcctgt gaactaattt ctctcaagga ttggttggac agcatctcct
     1381 actcagccct tgtgggcgat gtggtctgtg agaccccctt ccgtctacac ggcagggatt
     1441 tggacgaggt atccaagcag gaactttgtc caaggaaact catttctgac tacgagatga
     1501 ggccacagac tcctttaagc accacggggt atctacatac caccccagct tctgtaaact
     1561 ctgtggccac ttcttcctct gctgtttaca aacccccctt gaagcctcct aaggggaccc
     1621 gccagcccaa caaacccaga gtgcgcccca cttctaggca gccctctaaa gacttgggct
     1681 acagtaacta tggccccagc atagcctacc agaccaaatc cccggtgcct ttggaatgtc
     1741 ctacagcatg tacttgcaac ctgcagatct ctgatctggg tctcaatgtc aactgccaag
     1801 agcgcaagat cgagagcatc gcggagctgc agcccaagcc ctacaatccc aagaaaatgt
     1861 acctgacaga gaactatatc actgttgtgc gcagaacaga cttcctggaa gccaccggtc
     1921 tagacctcct gcacctgggt aataaccgca tctccatgat ccaggaccgg gcctttgggg
     1981 atctaggcaa cctgagacgc ctctatctga atggcaacag gattgagagg ctgagcccag
     2041 aattattcta tggcctgcag agcctgcagt atctcttcct ccagtacaat ctcatccgtg
     2101 agatccaggc tgggactttt gatcccgtcc caaacctcca gctgctattc ttgaataaca
     2161 accaactgca ggccatgcct tccggtgtct tctctggcct gacacttctc aggctgaacc
     2221 tgaggggtaa cagcttcact tccttgccag tgagtggagt tttggatcag ctgacttccc
     2281 tcattcaaat agatctacat gacaaccctt gggattgtac ctgcgacgtg gtgggcatga
     2341 agctgtggat tgagcagctc aaagtggggg tgttagtgga cgaagtgatc tgtaaggcgc
     2401 ccaagaaatt cgcagagacc tacatgcggt ccatcaagtc tgaactgcta tgcccagact
     2461 actctgatgt ggtggtttcc acgcccacgc cctcttccat ccaggtacca tccaggacga
     2521 acgcagcgac tccagctgtg aggttgaata gcactgggac ccccgcaggc ttaggagctg
     2581 ggacgggggc atcctctgtg cccttatccg tgttgatcct cagtctgctg ctggttttca
     2641 tcatgtccgt ctttgtggca gcaggccttt tcgtgctggt catgaaacgg aggaaaaaga
     2701 accagagcga ccacaccagt accaacaatt ccgacgtgag ctctttcaac atgcagtaca
     2761 gcgtgtatgg gggtggaggc ggcggcgggg gtggccaccc acacgcacac gtgcaccatc
     2821 gcgggcctgc gctgcccaag gtgaagactc ccgcgggcca cgtgtatgaa tacatccctc
     2881 accccctggg ccacatgtgc aagaacccca tctaccggtc tcgagaaggc aattccgtgg
     2941 aggattacaa agacctgcac gagctcaagg tcacttacag cagcaaccac cacctgcagc
     3001 agcagccgcc gccgccgccg caacagcccc agcagcagcc ccctccgcag atgcagatgc
     3061 agcctgggga ggaggagagg cgggaaagcc accatttgag gagccccgcc tacagcgtca
     3121 gcaccatcga gccccgagag gacctactgt cgccggtgca ggacgctgat cgcttttaca
     3181 ggggcatttt agagccagac aaacactgct ccactacccc tgcgggcagc agcctcccag
     3241 aataccctaa attcccatgc agcccggctg cttacacttt ctccccaaac tatgacctgc
     3301 gacgccccca tcagtatttg cacccgggtg caggggagag caggctgcgg gaaccggtgc
     3361 tctacagccc tccgggtgct gtctttgtag aaccgaaccg gaacgagtac ctggagttaa
     3421 aagcaaaact caatgttgag ccggactacc tcgaagtgct ggaaaaacag accacattta
     3481 gtcagttcta aaaaacaaag aaactctctt ggagcttttg cgtttagaac aagcaagcaa
     3541 gcagacacac tcggtgaacc catttgatta attgtgtcgt ttcaacattt agggcgaagt
     3601 gccttggcac gggattctca gcttcggtgg aagctaaccg aaagggtgtg caatttcctt
     3661 ttaattttac acgcgggaaa catttgtgta aactaggcac atcactttcg cttcttgtct
     3721 gtgggggaag acagaagggc tttctggagg gcgatttgca tcaagagtga cttgaaacag
     3781 gttgtggtcc ctttggcgga gctctgaagt tctgaggagg gtgctggtgg aagcagctta
     3841 gattcttctc atctttttgc tcctcttccc acactcttct ccttagagca ttggttgaga
     3901 gattagcaca ccccaacgtt ataggaagtt tgttctctct cacttctcct cccacccctc
     3961 ccaccttccc tcctcaatcc tttcctttgt ttttaaagga tgtgtttgta tgcattctgg
     4021 acgtctgaat taaaaaaaaa aatcttgtga tccagaaagg ctcactctag atgtggacaa
     4081 atcattaaaa ttacagagct atatgatcca taattgatta gtcaaaataa cttattgatg
     4141 aaatatacaa atattttatt gtagcaccta tttttatatg cacatttagc attcctcttt
     4201 ccttcactat ttagcctatg attttcacag aggcgtcgtt gcactggatt cgctgcgttc
     4261 ccaaaactag agtgatatca gaaaggccta ttaaatattt aaagacgtgg agaaataatg
     4321 gtgaaagtct ttaaaagtac ataccaccca tccaatggga cctgaaatta gaaagaaaaa
     4381 aaaaaaaaaa cacaagaaac taaaaaatga agctgtttgt atcccagtat ataaaaggag
     4441 aaaagatggg gcaatgaatt ggtttgttcc atggggaaat gtgtatacgt ttttggttgt
     4501 atcagagaag tttgaaaaat atttttatta gtgaaccaaa atgatgtatt gatttgacta
     4561 ctattgtagc cgattttttt gattgtgtaa ccaaacccag ttgcatttgt acagatccac
     4621 gtgcacttgc acttcagaag accaaatgat gggctgtaca agtctctgta tgatgtcttt
     4681 atccctctgg gcagatgcta atgacaagca ggacctctga aagacagaac tactattgtt
     4741 acagtctcat atgtatccca gcacatgtaa ttttttaaat agtttctgaa taaacacttg
     4801 ataactaaaa aaaaaaaaaa aaaaaaaaa
//
